Near infrared spectroscopy of the type IIn SN 2010jl: evidence for high velocity ejecta

The Type IIn supernova SN 2010jl was relatively nearby and luminous, allowing detailed studies of the near-infrared (NIR) emission. We present 1 - 2.4 micron spectroscopy over the age range of 36 - 565 days from the earliest detection of the supernova. On day 36, the H lines show an unresolved narrow emission component along with a symmetric broad component that can be modeled as the result of electron scattering by a thermal distribution of electrons. Over the next hundreds of days, the broad components of the H lines shift to the blue by 700 km/s, as is also observed in optical lines. The narrow lines do not show a shift, indicating they originate in a different region. He I 1.0830 and 2.0587 micron lines both show an asymmetric broad emission component, with a shoulder on the blue side that varies in prominence and velocity from -5500 km/s on day 108 to -4000 km/s on day 219. This component may be associated with the higher velocity flow indicated by X-ray observations of the supernova. The absence of the feature in the H lines suggests that this is from a He rich ejecta flow. The He I 1.0830 micron feature has a narrow P Cygni line, with absorption extending to ~100 km/s and strengthening over the first 200 days, and an emission component which weakens with time. At day 403, the continuum emission becomes dominated by a blackbody spectrum with a temperature of ~1900 K, suggestive of dust emission.Comment: 17 pages, 18 figure

Hubble Space Telescope WFPC2 Imaging of SN 1979C and Its Environment

The locations of supernovae in the local stellar and gaseous environment in galaxies contain important clues to their progenitor stars. As part of a program to study the environments of supernovae using Hubble Space Telescope (HST) imaging data, we have examined the environment of the Type II-L SN 1979C in NGC 4321 (M100). We place more rigorous constraints on the mass of the SN progenitor, which may have had a mass M \approx 17--18 M_sun. Moreover, we have recovered and measured the brightness of SN 1979C, m=23.37 in F439W (~B; m_B(max) = 11.6), 17 years after explosion. .Comment: 18 pages, 8 figures, submitted to PAS

A Synthetic Genetic Edge Detection Program

SummaryEdge detection is a signal processing algorithm common in artificial intelligence and image recognition programs. We have constructed a genetically encoded edge detection algorithm that programs an isogenic community of E. coli to sense an image of light, communicate to identify the light-dark edges, and visually present the result of the computation. The algorithm is implemented using multiple genetic circuits. An engineered light sensor enables cells to distinguish between light and dark regions. In the dark, cells produce a diffusible chemical signal that diffuses into light regions. Genetic logic gates are used so that only cells that sense light and the diffusible signal produce a positive output. A mathematical model constructed from first principles and parameterized with experimental measurements of the component circuits predicts the performance of the complete program. Quantitatively accurate models will facilitate the engineering of more complex biological behaviors and inform bottom-up studies of natural genetic regulatory networks

Optical and Ultraviolet Spectroscopy of SN 1995N: Evidence for Strong Circumstellar Interaction

Optical and ultraviolet observations of the Type IIn supernova SN 1995N at epochs between 321 and 1799 days after the explosion show three distinct velocity components. The narrow lines come from circumstellar gas and show both low and high ionization. This component has a low filling factor and is photoionized by X-rays from the shock. The intermediate component, which is dominated by newly processed oxygen, originates in a shell with velocity of 2500-5000 km s-1 and most likely comes from the ejecta. The hydrogen- and helium-dominated gas has a low ionization, a high density, and velocities that extend out to 10,000 km s-1. Strong signatures of Lyα-pumped fluorescence lines of Fe II are seen in the near-infrared and ultraviolet. The He/H ratio, ~0.3 by number, and the nitrogen overabundance provide strong evidence for CNO-burning products. The fluxes of the broad hydrogen and helium lines decrease considerably faster than the oxygen lines. The Hα line profile shows strong evolution, with the red wing decreasing faster than the blue. Possible scenarios, involving either a clumpy circumstellar medium or an aspherical distribution of the surrounding gas, are discussed based on the line profiles and physical conditions. Finally, we propose that Type IIn supernovae have their origin in red supergiants in a superwind phase

Detailed Analysis of Early to Late-Time Spectra of Supernova 1993J

We present a detailed study of line structure in early to late-time spectra of Supernova (SN) 1993J. Spectra during the nebular phase, but within the first two years after explosion, exhibit small-scale structure in the emission lines of some species, notably oxygen and magnesium, showing that the ejecta of SN 1993J are clumpy. On the other hand, a lack of structure in emission lines of calcium implies that the source of calcium emission is uniformly distributed throughout the ejecta. These results are interpreted as evidence that oxygen emission originates in clumpy, newly synthesized material, while calcium emission arises from material pre-existing in the atmosphere of the progenitor. Spectra spanning the range 433-2454 days after the explosion show box-like profiles for the emission lines, clearly indicating circumstellar interaction in a roughly spherical shell. This is interpreted within the Chevalier & Fransson (1994) model for SNe interacting with mass lost during prior stellar winds. At very late times, the emission lines have a two-horned profile, implying the formation of a somewhat flattened or disk-like structure that is a significant source of emission. The very high signal-to-noise ratio spectra are used to demonstrate the potential significance of misinterpretation of telluric absorption lines in the spectra of bright SNe.Comment: 34 pages, 16 figures, AASTeX V5.0. Accepted for publication in A

Measurement of three-jet differential cross sections d sigma-3jet / d M-3jet in p anti-p collisions at sqrt(s)=1.96 TeV

We present the first measurement of the inclusive three-jet differential cross section as a function of the invariant mass of the three jets with the largest transverse momenta in an event in p anti-p collisions at sqrt(s) = 1.96 TeV. The measurement is made in different rapidity regions and for different jet transverse momentum requirements and is based on a data set corresponding to an integrated luminosity of 0.7 fb^{-1} collected with the D0 detector at the Fermilab Tevatron Collider. The results are used to test the three-jet matrix elements in perturbative QCD calculations at next-to-leading order in the strong coupling constant. The data allow discrimination between parametrizations of the parton distribution functions of the proton.Comment: 10 pages, 4 figures, 2 tables, submitted to Phys. Lett. B, corrected chi2 values for NNPD

Measurement of the production of a W boson in association with a charm quark in pp collisions at √s = 7 TeV with the ATLAS detector

The production of a W boson in association with a single charm quark is studied using 4.6 fb−1 of pp collision data at s√ = 7 TeV collected with the ATLAS detector at the Large Hadron Collider. In events in which a W boson decays to an electron or muon, the charm quark is tagged either by its semileptonic decay to a muon or by the presence of a charmed meson. The integrated and differential cross sections as a function of the pseudorapidity of the lepton from the W-boson decay are measured. Results are compared to the predictions of next-to-leading-order QCD calculations obtained from various parton distribution function parameterisations. The ratio of the strange-to-down sea-quark distributions is determined to be 0.96+0.26−0.30 at Q 2 = 1.9 GeV2, which supports the hypothesis of an SU(3)-symmetric composition of the light-quark sea. Additionally, the cross-section ratio σ(W + +c¯¯)/σ(W − + c) is compared to the predictions obtained using parton distribution function parameterisations with different assumptions about the s−s¯¯¯ quark asymmetry

Pan-Cancer Analysis of lncRNA Regulation Supports Their Targeting of Cancer Genes in Each Tumor Context

Long noncoding RNAs (lncRNAs) are commonly dys-regulated in tumors, but only a handful are known toplay pathophysiological roles in cancer. We inferredlncRNAs that dysregulate cancer pathways, onco-genes, and tumor suppressors (cancer genes) bymodeling their effects on the activity of transcriptionfactors, RNA-binding proteins, and microRNAs in5,185 TCGA tumors and 1,019 ENCODE assays.Our predictions included hundreds of candidateonco- and tumor-suppressor lncRNAs (cancerlncRNAs) whose somatic alterations account for thedysregulation of dozens of cancer genes and path-ways in each of 14 tumor contexts. To demonstrateproof of concept, we showed that perturbations tar-geting OIP5-AS1 (an inferred tumor suppressor) andTUG1 and WT1-AS (inferred onco-lncRNAs) dysre-gulated cancer genes and altered proliferation ofbreast and gynecologic cancer cells. Our analysis in-dicates that, although most lncRNAs are dysregu-lated in a tumor-specific manner, some, includingOIP5-AS1, TUG1, NEAT1, MEG3, and TSIX, synergis-tically dysregulate cancer pathways in multiple tumorcontexts

Genomic, Pathway Network, and Immunologic Features Distinguishing Squamous Carcinomas

This integrated, multiplatform PanCancer Atlas study co-mapped and identified distinguishing molecular features of squamous cell carcinomas (SCCs) from five sites associated with smokin

Pan-cancer Alterations of the MYC Oncogene and Its Proximal Network across the Cancer Genome Atlas

Although theMYConcogene has been implicated incancer, a systematic assessment of alterations ofMYC, related transcription factors, and co-regulatoryproteins, forming the proximal MYC network (PMN),across human cancers is lacking. Using computa-tional approaches, we define genomic and proteo-mic features associated with MYC and the PMNacross the 33 cancers of The Cancer Genome Atlas.Pan-cancer, 28% of all samples had at least one ofthe MYC paralogs amplified. In contrast, the MYCantagonists MGA and MNT were the most frequentlymutated or deleted members, proposing a roleas tumor suppressors.MYCalterations were mutu-ally exclusive withPIK3CA,PTEN,APC,orBRAFalterations, suggesting that MYC is a distinct onco-genic driver. Expression analysis revealed MYC-associated pathways in tumor subtypes, such asimmune response and growth factor signaling; chro-matin, translation, and DNA replication/repair wereconserved pan-cancer. This analysis reveals insightsinto MYC biology and is a reference for biomarkersand therapeutics for cancers with alterations ofMYC or the PMN