84 research outputs found
The Architecture of Contemporary Healthcare Reform and Effective Marginal Tax Rates
- Author
- Publication venue
- MC Law Digital Commons
- Publication date
- 01/01/2010
- Field of study
Symposiu
Regulation by Calculator: Experience Under the Affordable Care Act
- Author
- Publication venue
- Digital Commons at Michigan State University College of Law
- Publication date
- 01/01/2016
- Field of study
Article published in the Michigan State Law Review
Accelerated evolution of SARS-CoV-2 in free-ranging white-tailed deer
- Author
- Bevins Sarah N.
- Bowman Andrew S.
- Chandler Jeffrey C.
- DeLiberto Thomas J.
- Faith Seth A.
- Franks John
- Garushyants Sofya K.
- Genders J. Tyler
- Huey Devra
- Jeevan Trushar
- Kandeil Ahmed
- Kasnyik Kevin
- Koonin Eugene V.
- Lemey Philippe
- Lenoch Julianna B.
- Linder Timothy J.
- Magee Andrew F.
- McBride Dillon S.
- Miller Lance
- Montoney Andrew J.
- Nelson Martha I.
- Nolting Jacqueline M.
- Overend Steven H.
- Patel Anami
- Suchard Marc A.
- Tonkovich Michael J.
- Trifkovic Sanja
- Webby Richard J.
- Williams Amanda M.
- Publication venue
- DigitalCommons@University of Nebraska - Lincoln
- Publication date
- 01/12/2023
- Field of study
The zoonotic origin of the COVID-19 pandemic virus highlights the need to fill the vast gaps in our knowledge of SARS-CoV-2 ecology and evolution in non-human hosts. Here, we detected that SARS-CoV-2 was introduced from humans into white-tailed deer more than 30 times in Ohio, USA during November 2021-March 2022. Subsequently, deer-to-deer transmission persisted for 2–8 months, disseminating across hundreds of kilometers. Newly developed Bayesian phylogenetic methods quantified how SARS-CoV-2 evolution is not only three-times faster in white-tailed deer compared to the rate observed in humans but also driven by different mutational biases and selection pressures. The long-term effect of this accelerated evolutionary rate remains to be seen as no critical phenotypic changes were observed in our animal models using white-tailed deer origin viruses. Still, SARS-CoV-2 has transmitted in white-tailed deer populations for a relatively short duration, and the risk of future changes may have serious consequences for humans and livestock
Recommended from our members
Redirecting research efforts on the diversification-performance linkage: The search for synergy
- Author
- Aggarwal R. K.
- Ahuja G.
- Ahuja G.
- Ahuja G.
- Amihud Y.
- Amit R.
- Amit R.
- Anand J.
- Anjos F.
- Argyres N.
- Argyres N. S.
- Arikan A. M.
- Arrow K. E.
- Baldwin C. Y.
- Barney J. B.
- Barroso A.
- Barton S. L.
- Baum J. A.
- Bens D. A.
- Berger P. G.
- Berger P. G.
- Bergh D. D.
- Berry C. H.
- Bettis R. A.
- Bettis R. A.
- Bettis R. A.
- Busija E. C.
- Calvo G. A.
- Campa J. M.
- Capon N.
- Capron L.
- Cardinal L. B.
- Cardinal L. B.
- Cardinal L. B.
- Cardinal L. B.
- Caves R. E.
- Chandler A. D.
- Chang S. J.
- Chang S. J.
- Chang Y.
- Chari M. D.
- Chatterjee S.
- Chatterjee S.
- Chatterjee S.
- Chatterjee S.
- Chavas J. P.
- Chittoor R.
- Christensen H. K.
- Clark J. R.
- Coase R. H.
- Custodio C.
- David P.
- Davis G. F.
- Davis P. S.
- Davis R.
- Davis R.
- de Figueiredo R. J.
- Denis D. J.
- Denis D. J.
- Dimitrov V.
- Dittmar A.
- Dubofsky P.
- Edwards C. D.
- Elena Novelli
- Erdorf S.
- Farjoun M.
- Farjoun M.
- Feldman E. R.
- Feldman E. R.
- Fligstein N.
- Franco F.
- Galbraith J. R.
- Gartenberg C.
- Gary M. S.
- Gautam Ahuja
- Ghemawat P.
- Gomes J.
- Gomez-Mejia L. R.
- Gopalan R.
- Gort M.
- Graham J. R.
- Grant R. M.
- Grant R. M.
- Greenwood R.
- Greve H. R.
- Hall B. H.
- Hall E. H.
- Hamel G.
- Harris M.
- Harrison J. S.
- Hart O.
- Hashai N.
- Haveman H. A.
- Hayn C.
- Helfat C. E.
- Hill C. W.
- Hill C. W.
- Hill C. W.
- Hill C. W.
- Hill C. W.
- Hoskisson R. E.
- Hoskisson R. E.
- Hoskisson R. E.
- Hoskisson R. E.
- Hoskisson R. E.
- Hoskisson R. E.
- Hoskisson R. E.
- Hyland D. C.
- Ilinitch A. Y.
- Jacobides M. G.
- Jacquemin A. P.
- Jensen M. C.
- Jensen M. C.
- Jensen M. C.
- Jensen M. C.
- Jensen M. C.
- Johnson G.
- Jones G. R.
- Kang J.
- Kaplan S.
- Karim S.
- Karnani A.
- Kay N. M.
- Kay N. M.
- Kazanjian R. K.
- Keats B. W.
- Keren M.
- Khanna T.
- Khanna T.
- Khanna T.
- Kim S. K.
- Klein B.
- Klein P. G.
- Klein P. G.
- Kogut B.
- Kumar M. S.
- Kumar M. V.
- Kuppuswamy V.
- Lamont B. T.
- Lamont O. A.
- Lane P. J.
- Lane P. J.
- Lang L. H. P.
- Lange D.
- Lecraw D. J.
- Leonard‐Barton D.
- Levinthal D. A.
- Levinthal D. A.
- Levy H.
- Lewellen W. G.
- Li S. X.
- Lintner J.
- Litov L. P.
- Lubatkin M.
- Lubatkin M.
- Lubatkin M.
- Lubatkin M.
- Lubatkin M.
- Lubatkin M.
- Lyandres E.
- Mahoney J. T.
- Maksimovic V.
- Mansi S. A.
- Markham J. W.
- Markides C. C.
- Markides C. C.
- Markides C. C.
- Markides C. C.
- Martin J. D.
- Matusik S. F.
- May D. O.
- Mayer M.
- McDougal F. M.
- McWilliams A.
- Melicher R. W.
- Meyer M.
- Michel A.
- Milgrom P.
- Milgrom P.
- Miller C. C.
- Miller D. J.
- Miller D. J.
- Miller D. J.
- Mitchell W.
- Montgomery C. A.
- Montgomery C. A.
- Montgomery C. A.
- Montgomery C. A.
- Myerson R. B.
- Natividad G.
- Nelson R. R.
- Nguyen T. H.
- Nocker E.
- Normann R.
- Normann R.
- North D. C.
- Novelli E.
- Oestreicher-Singer G.
- O’Brien J. P.
- Palepu K.
- Palich L. E.
- Park C.
- Penrose E. T.
- Peteraf M. A.
- Pitts R. A.
- Porter M. E.
- Porter M. E.
- Prahalad C. K.
- Puranam P.
- Rajan R.
- Rawley E.
- Rawley E.
- Ray G.
- Roberts E. B.
- Robins J.
- Robins J. A.
- Rosen S.
- Rumelt R.
- Rumelt R. P.
- Sakhartov A. V.
- Santalo J.
- Scharfstein D. S.
- Scharfstein D. S.
- Scott J. H.
- Servaes H.
- Seth A.
- Sharpe W. F.
- Shin H. H.
- Shleifer A.
- Siggelkow N.
- Silhan P. A.
- Silverman B. S.
- Simmonds P. G.
- Slater M.
- St. John C. H.
- Stephen A. T.
- Stern I.
- Stimpert J. L.
- Stulz R. M.
- Su W.
- Sutherland J. W.
- Tanriverdi H.
- Tanriverdi H.
- Teece D. J.
- Teece D. J.
- Teece D. J.
- Treynor J. L.
- Varadarajan P. R.
- Villalonga B.
- Wan W. P.
- Wernerfelt B.
- Wernerfelt B.
- Wernerfelt B.
- Wernerfelt B.
- Weston J. F.
- Whited T. M.
- Williamson O. E.
- Wu B.
- Ye G.
- Zahavi T.
- Zenger T.
- Zhou Y. M.
- Zuckerman E. W.
- Zuckerman E. W.
- Publication venue
- 'Academy of Management'
- Publication date
- 01/01/2017
- Field of study
We review the literature on the diversification-performance (D-P) relationship to a) propose that the time is ripe for a renewed attack on understanding the relationship between diversification and firm performance, and b) outline a new approach to attacking the question. Our paper makes four main contributions. First, through a review of the literature we establish the inherent complexities in the D-P relationship and the methodological challenges confronted by the literature in reaching its current conclusion of a non-linear relationship between diversification and performance. Second, we argue that to better guide managers the literature needs to develop along a complementary path – whereas past research has often focused on answering the big question of does diversification affect firm performance, this second path would focus more on identifying the precise micro-mechanisms through which diversification adds or subtracts value. Third, we outline a new approach to the investigation of this topic, based on (a) identifying the precise underlying mechanisms through which diversification affects performance; (b) identifying performance outcomes that are “proximate” to the mechanism that the researcher is studying, and (c) identifying an appropriate research design that can enable a causal claim. Finally, we outline a set of directions for future research
Prognostic model to predict postoperative acute kidney injury in patients undergoing major gastrointestinal surgery based on a national prospective observational cohort study.
- Author
- Aamir A
- Abbas J
- Abbas N
- Abbott TEF
- Abdalla M
- Abdikadir H
- Abuhussein N
- Acquaah F
- Adamson R
- Adeleye O
- Adeogun A
- Adlan A
- Aftab R
- Afzal Z
- Agarwal M
- Aglan H
- Agnew CJF
- Agrawal R
- Ahern D
- Ahluwalia J
- Ahluwalia V
- Ahmad A
- Ahmad K
- Ahmed H
- Ahmed I
- Ahmed L
- Ahmed N
- Ahmed P
- Ainger E
- Ainsworth P
- Aishwarya G
- Ajibola-Taylor O
- Akhbari M
- Akhtar A
- Akhtar R
- Akpenyi O
- Al-Ausi M
- Al-Huneidi R
- Al-Khudairi R
- Al-Masri S
- Al-Mousawi A
- Al-Saadi N
- Alagappan A
- Alberts J
- Alfa-Wali M
- Ali A
- Ali B
- Ali I
- Ali M
- Ali Q
- Ali S
- Alturki N
- Alwandi A
- Amani L
- Amarnath T
- Amer M
- Amin H
- Amin MN
- Amoah R
- Amoah-Arko A
- Anandarajah C
- Ananthavarathan P
- Andah EJE
- Andrew K
- Andrews H
- Ang A
- Ang HL
- Ang JJ
- Ani C
- Anilkumar A
- Anto N
- Anwar S
- Apperley H
- Appleton S
- Aquilina T
- Archer M
- Arif T
- Arneill M
- Arnell S
- Arnold TJ
- Arshad A
- Arthur J
- Arulkumaran N
- Arya J
- Asad M
- Asemota N
- Ashaye T
- Ashdown T
- Ashour R
- Ashraf MR
- Ashwood J
- Asif U
- Atkin G
- Atkins B
- Attalla M
- Aubrey-Jones D
- Auckburally S
- Auld F
- Auluck I
- Azam S
- Aziz R
- Azizi A
- Azmi F
- Babatunde F
- Babu VS
- Bachi A
- Bagga R
- Bains H
- Bajwa DS
- Baker A
- Baker C
- Balai E
- Balian V
- Ball M
- Bamford M
- Bana R
- Banfield DA
- Bannard-Smith J
- Barai I
- Barclay J
- Barfi L
- Barker C
- Barker M
- Barmayehvar B
- Barnfield J
- Barnor-Ahiaku E
- Baron C
- Barr CJ
- Barraclough J
- Baryan HK
- Basra M
- Bassam N
- Bath MF
- Battle J
- Beasley W
- Beattie G
- Beattie S
- Beatty M
- Beghal G
- Begum F
- Behranwala K
- Belchos J
- Belgaid DR
- Belgaumkar A
- Bell S
- Ben-Gal O
- Benchetrit S
- Bennett M
- Benons N
- Bernal TL
- Bertelli M
- Berthaume-Hawkins SD
- Best R
- Betts A
- Bevan K
- Bews-Hair M
- Bhambra R
- Bhamra N
- Bhangu A
- Bhatte S
- Bhatti A
- Bhide I
- Bhome R
- Bhudia R
- Bhullar S
- Bienias A
- Billyard C
- Bird C
- Birkinshaw F
- Black J
- Blake E
- Blazeby JM
- Bleakley A
- Bloom I
- Bogle R
- Bolton W
- Borakati A
- Boraluwe-Rallage H
- Borg CM
- Botha A
- Boualbanat Y
- Boulton APR
- Bountra K
- Bowley D
- Boyd G
- Boyles L
- Bradley P
- Brannick S
- Brayley J
- Brecher J
- Breen H
- Bristow S
- Britton N
- Broad J
- Brobbey P
- Brock E
- Brooke M
- Brown A
- Brown B
- Brown F
- Brown FS
- Brown H
- Brown K
- Brown LR
- Brown M
- Brown N
- Brown R
- Brown S
- Brown T
- Bruce C
- Bruce P
- Budd E
- Bull K
- Burgin A
- Burke D
- Burke J
- Burnage S
- Burns N
- Burrows A
- Busti S
- Butler A
- Cabdi NMO
- Cadden F
- Cairns C
- Calabria C
- Calciu A
- Campbell A
- Campbell B
- Campbell G
- Campbell HS
- Cannon SP
- Cant M
- Capella S
- Cardus C
- Cardwell A
- Cargill Z
- Caroll P
- Carr G
- Carr R
- Carr W
- Carse S
- Carter N
- Carter R
- Castle A
- Cato L
- Cave D
- Cecil E
- Chadwick H
- Chadwick M
- Chan F
- Chan L
- Chan M
- Chan SSN
- Chan-lam N
- Chandler E
- Chandler S
- Chandramoorthy L
- Chandramoorthy S
- Chang A
- Chang LH
- Chang M
- Chappelow I
- Chapple K
- Charnley R
- Chaudhry A
- Chaudhry S
- Chauhan P
- Chavan A
- Chean CS
- Chen L
- Chen Y
- Chenciner L
- Cheng J
- Chesner R
- Cheung W
- Chin YR
- China Z
- Chitsabesan P
- Chohan K
- Choi JE
- Chong A
- Chong P
- Choo S
- Chopada A
- Chouari T
- Choudhary Y
- Choudhry M
- Choy CH
- Christie S
- Christopher E
- Chudek D
- Chui J
- Church M
- Church R
- Cipparrone M
- Claireaux HA
- Clark K
- Clarke B
- Clement KD
- Clements B
- Clements SE
- Cobley H
- Coe P
- Cohen J
- Coldicutt O
- Cole A
- Coleman M
- Collaborative S
- Collins J
- Collishaw A
- Common M
- Concannon K
- Conchie H
- Connelly A
- Connor M
- Cookson P
- Cope EA
- Cope T
- Copeland M
- Copley HC
- Coppel J
- Corbridge O
- Cotter M
- Courquin GR
- Court J
- Cox L
- Craig ARJ
- Craig N
- Crane E
- Cremen S
- Cresswell B
- Crewe A
- Crilly C
- Crilly L
- Croghan N
- Croitoru C
- Cromwell D
- Cronbach P
- Crook H
- Crozier L
- Cruddas L
- Cullum R
- Cumber E
- Cumming S
- Cummings D
- Cunliffe L
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- Curtis A
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- D'Auria M
- D'Souza F
- Dada J
- Dalal F
- Dalrymple J
- Daly D
- Daniels J
- Das E
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- Datta U
- Davies E
- Davies G
- Davies J
- Davies P
- Davis H
- Davison C
- Dawe V
- Dawood S
- Day L
- De Cates C
- De Freitas M
- Dean S
- Debnath D
- Deekonda P
- Deepak S
- Deery L
- Delvi A
- Denley S
- Dennahy IS
- Dennis R
- Dennis Y
- Desai H
- Desai K
- Devalia S
- Dhaliwal R
- Dhillon AK
- Dhillon P
- Dhir T
- Dhuna S
- Diamond J
- Dib NP
- Dickson G
- Dietrich A
- Dindyal S
- Dixon O
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- Dobrzynska M
- Doherty C
- Donaldson G
- Donohoe C
- Doshi A
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- Downes C
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- Drake TM
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- Dudley B
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- Duggal A
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- Dupaguntla YS
- Durand C
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- Durham-Hall A
- Durno J
- Durrigan T
- Duthie F
- Dutta A
- Dyal A
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- Easby S
- Easdon S
- Eastwood M
- Ebhogiaye O
- Eccles L
- Ecclestone T
- Eddama M
- Edgerton K
- Edozie F
- Edwin C
- Egan E
- Eiben I
- Eiben P
- Eilon T
- El Matary R
- El Tokhy O
- El-Sawy D
- El-Taji O
- Elangovan S
- Elbuzidi M
- Elder P
- Elias J
- Ellerby N
- Elliot J
- Elliott J
- Elsaddig M
- Elseedawy E
- Emberton J
- En BNW
- Engledow A
- English W
- Epanomeritakis E
- Episkopos C
- Epstein J
- Esmail R
- Evans D
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- Evans R
- Ezzat A
- Fafemi O
- Falamarzi A
- Fam M
- Faraj A
- Farhan-Alanie MMH
- Farmer N
- Farooq M
- Farooqi M
- Farrar E
- Farwana M
- Faulkner S
- Fawole A
- Fearnhead N
- Feldman M
- Fenton K
- Ferris B
- Filipescu T
- Finch E
- Fitzgerald I
- Fitzgerald JE
- Fitzpatrick H
- Flack V
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- Foley MP
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- Fowler AJ
- Fox H
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- Freeman SK
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- Friend C
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- Gaddah M
- Gadsby C
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- Galea M
- Gallogly P
- Galloway F
- Gammeri E
- Gani A
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- Gao C
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- Garsaa T
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- Ghailan N
- Gharatya A
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- Gidwani A
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- Gnanappiragasam D
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- Goodson R
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- Gordon J
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- Gower T
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- Gravell R
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- Greenan E
- Greenhalgh S
- Gregoriou K
- Gregory C
- Gresly J
- Grey A
- Gribbon C
- Griffith J
- Griffiths B
- Griffiths H
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- Gruhn A
- Guevel B
- Guillotte C
- Gulzar I
- Gundogan B
- Gunwa T
- Gupta A
- Gupta R
- Gurjar S
- Gurung E
- Guy C
- Gwilym B
- Gwozdz AM
- Hack J
- Hackney E
- Haddad S
- Hague M
- Hair J
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- Hallan R
- Hamdan K
- Hamid H
- Hammad A
- Hanson M
- Haq T
- Haque A
- Haray P
- Hare L
- Harinath G
- Harlinska A
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- Harris S
- Harrison E
- Harrison EM
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- Hart SJ
- Harte J
- Hartley J
- Hartley M
- Harty M
- Hashemi R
- Hassanin K
- Hathaway C
- Haughey B
- Hawthorne T
- Hayashi E
- Hayat A
- Hayat F
- Hayes JDB
- Haynes K
- Haynes S
- Hayward J
- Haywood E
- Hazeldine P
- He YY
- Hedley C
- Helliwell R
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- Henry J
- Henshaw V
- Herman A
- Hernon J
- Heywood E
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- Hill N
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- Hodgson B
- Hodgson S
- Hogg G
- Holdsworth R
- Hole J
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- Holmes D
- Holt F
- Hopkins M
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- Horseman C
- Hosamuddin H
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- Houlton J
- Howlader M
- Hrvacic N
- Hubert J
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- Hughes EJ
- Hughes J
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- Huisman L
- Hull K
- Hung YMA
- Hungwe C
- Hunt C
- Huppatz IW
- Huq T
- Hurst P
- Hussain A
- Hussain M
- Hussain SF
- Hussain ST
- Hussein N
- Hutchinson S
- Ibrahim B
- Ibrahim I
- Ijeomah A
- Ikogho O
- Ikram B
- Ilenkovan N
- Imam SZ
- Imran H
- Ingleton R
- Ingram H
- Innes R
- Iqbal F
- Iqbal S
- Iroegbu U
- Ishaq H
- Islam Y
- Ismail O
- Ito G
- Ivo T
- Jackman T
- Jackson CES
- Jacob-Ramsdale B
- Jain D
- Jain P
- Jamal S
- James F
- Javaid NR
- Jawad L
- Jawad ZAR
- Jebakumar R
- Jeffreys N
- Jeyabaladevan S
- Ji C
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- Jiao LR
- John I
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- Jordan P
- Joseph R
- Joyce H
- Joyner C
- Jull P
- Kale A
- Kamarajah S
- Kambasha C
- Kaminski F
- Kanabar S
- Kanapeckaite L
- Kandage D
- Kandhari N
- Kandiah K
- Kane D
- Kane L
- Kapp J
- Kaptanis S
- Karaj J
- Karam E
- Karbowiak M
- Karim MA
- Karim MJ
- Karmarkar A
- Karsan RB
- Karunatilleke AS
- Katira A
- Katsaiti I
- Kaur G
- Kausar A
- Kazmi Z
- Keane K
- Kee JY
- Keelan G
- Kelkar A
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- Kennedy ED
- Keogh C
- Kerin M
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- Kerrigan K
- Kersey T
- Kershaw S
- Keshvala C
- Kethees A
- Keyte A
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- Khalil M
- Khaliq M
- Khan A
- Khan H
- Khan K
- Khan M
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- Khatri C
- Khaw J
- Khawaja H
- Khawar H
- Khawari S
- Khodatars K
- Khoo E
- Kiandee M
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- STARSurg Collaborative Writing Committee, Data analysis, Steering committee, Advisory group, Regional leads, Collaborators and validators
- STARSurg Collaborative Writing Committee, Data analysis, Steering committee, Advisory group, Regional leads, Collaborators and validators, Nepogodiev, D
- Stechman M
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- Zubikarai G
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- Publication venue
- 'Wiley'
- Publication date
- 18/05/2018
- Field of study
Background: Acute illness, existing co-morbidities and surgical stress response can all contribute to postoperative acute kidney injury (AKI) in patients undergoing major gastrointestinal surgery. The aim of this study was prospectively to develop a pragmatic prognostic model to stratify patients according to risk of developing AKI after major gastrointestinal surgery. Methods: This prospective multicentre cohort study included consecutive adults undergoing elective or emergency gastrointestinal resection, liver resection or stoma reversal in 2-week blocks over a continuous 3-month period. The primary outcome was the rate of AKI within 7 days of surgery. Bootstrap stability was used to select clinically plausible risk factors into the model. Internal model validation was carried out by bootstrap validation. Results: A total of 4544 patients were included across 173 centres in the UK and Ireland. The overall rate of AKI was 14·2 per cent (646 of 4544) and the 30-day mortality rate was 1·8 per cent (84 of 4544). Stage 1 AKI was significantly associated with 30-day mortality (unadjusted odds ratio 7·61, 95 per cent c.i. 4·49 to 12·90; P < 0·001), with increasing odds of death with each AKI stage. Six variables were selected for inclusion in the prognostic model: age, sex, ASA grade, preoperative estimated glomerular filtration rate, planned open surgery and preoperative use of either an angiotensin-converting enzyme inhibitor or an angiotensin receptor blocker. Internal validation demonstrated good model discrimination (c-statistic 0·65). Discussion: Following major gastrointestinal surgery, AKI occurred in one in seven patients. This preoperative prognostic model identified patients at high risk of postoperative AKI. Validation in an independent data set is required to ensure generalizability
ICAR: endoscopic skull‐base surgery
- Author
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- American Academy of Pediatrics Steering Committee on Quality Improvement and Management
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- Publication venue
- Publication date
- 01/07/2019
- Field of study
n/
Improving the first-line treatment of febrile illnesses in Ghana: willingness to pay for malaria rapid diagnostic tests at licensed chemical shops in the Kintampo area
- Author
- A Freeman
- A Ofosu
- AC Noordam
- Anthony Kwarteng
- B Genton
- B Uzochukwu
- B Uzochukwu
- CI Chandler
- Constance Bart-Plange
- D Baudon
- GHS
- GW Torrance
- H Reyburn
- H White
- J Akazili
- Keziah Malam
- Konrad Obermann
- KP Asante
- KS Hansen
- Kwaku Poku Asante
- Lawrence Febir
- LD Howe
- M Amexo
- M Mayxay
- P Bloland
- REM Mota
- S Owusu-Agyei
- S Tougher
- S Vyas
- Seth Owusu-Agyei
- T Tawiah
- TA Houweling
- Theresa Tawiah
- Vivian Aubyn
- W Asenso-Okyere
- W Rennie
- WHO
- WHO
- World Health Organization
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
Repensando redes estratégicas
- Author
- Ackroyd S
- Albert M
- Alexandre Faria
- Altvater E
- Alvesson M
- Arbix G
- Arbix G
- Axelsson B
- Barney J
- Bedê M
- Benko G
- Benson K
- Bertero C
- Best M
- Bettis R
- Bhaskar R
- Bhaskar R
- Bhaskar R
- Bignetti L
- Blaikie N
- Boisot M
- Brahm R
- Broad R
- Böhm S
- Carter C
- Chandler A
- Chandler A
- Chandler A. D
- Clark T
- Clegg S
- Clegg S
- Combe I
- Courpasson D
- Cummings S
- Dicken P
- Dicken P
- Fleetwood S
- Gaddis P
- Gereffi G
- Gereffi G
- Ghemawat P
- Ghoshal S
- Godfrey P
- Grandy G
- Gulati R
- Gulati R
- Haley G
- Hambrick D
- Harvey D
- Henderson J
- Hoskisson R
- Humphrey J
- Ibarra-Colado E
- Ikenberry G
- Kaplinski R
- Kay J
- Khurana R
- Kils U
- Knights D
- Koniordos S
- Kwan K
- Lamming R
- Laplane M
- Lecraw D
- Levy D
- Lorenzoni G
- Lowendahl B
- Machado-da-Silva C
- Marsden R
- Mattsson L.-G
- Mills C
- Mintzberg H
- Mir R
- Murtha T
- Ohmae K
- Oliver N
- Outhwaite W
- Outhwaite W
- Peng M
- Peng M
- Pettigrew A
- Phelan S
- Ramamurti R
- Ricart J
- Rodrígues-Pose A
- Ruigrok W
- Rumelt R
- Saraiva E
- Sayer A
- Schelhase M
- Schendel D
- Seth M
- Shrivastava P
- Sklair L
- Snow C
- Steger M
- Teece D
- Tsoukas H
- Tsoukas H
- Vergara S
- Walsh J
- Welch C
- Westwood R
- Whittington R
- Whittington R
- Whittington R
- Wilson D
- Womack J
- Yeung H
- Publication venue
- 'FapUNIFESP (SciELO)'
- Publication date
- Field of study
The Law and Economics of Liability Insurance: A Theoretical and Empirical Review
- Author
- Abraham L Wickelgren
- Alan O Sykes
- Albert Choi
- Albert Yoon
- Albert Yoon
- Alma &
- Alma Cohen
- Alma Cohen
- Andre Tunc
- Angela Hawken
- Anne Gron
- Anne Gron
- Bernard &
- Bernard S Black
- Brian Glenn
- Carol Heimer
- Catherine Sharkey
- Chris M Robinson
- Christian Lahnstein
- D&apos
- Daniel P Asmat
- David &
- David &
- David A Hyman
- David A Hyman
- David M Studdert
- Dwight M Jaffe
- Eric &
- Eric D Beal
- Francis J Mootz
- Frank Dobbin
- Froot
- Gary Schwartz
- George M Cohen
- George Priest
- Goran Skogh
- Guido Calabresi
- Guo
- H I R A Weisberg
- Hans-Werner Sinn
- Ian &
- J L Wang
- Jaap H Abbring
- Jaap H Abbring
- Jennifer Arlen
- Jennifer Arlen
- Jennifer Arlen
- Joan Gabel
- Joanna L Grossman
- John Core
- John E Calfee
- Jon &
- Jonathan Simon
- Joni Hersch
- Kathryn Zeiler
- Ken Dornstein
- Kenneth J Arrow
- Kenneth S Abraham
- Kenneth S Abraham
- Kenneth S Abraham
- Kent Syverud
- Kent Syverud
- Kyle D Logue
- Lori B Andrews
- Louis Carron
- Mark F Grady
- Mark Geistfeld
- Mark Israel
- Mary Mcneely
- Michael E Staten
- Michael Rothschild
- Nancy H Van Der Veer
- Neil Vidmar
- Patricia Born
- Patrick L Brockett
- Peter Siegelman
- Philip J Cook
- Pierre Picard
- Ralph A
- Richard &
- Richard &
- Richard A Epstein
- Richard Abel
- Richard J Butler
- Richard Macminn
- Robert &
- Robert D Cooter
- Robert E Hoyt
- Ronen
- Sachin Pandya
- Scott E Harrington
- Scott Harringon
- Scott Harrington
- Sean Fitzpatrick
- Sean W Gallagher
- Seth J Chandler
- Sharon Tennyson
- Sharon Tennyson
- Sharon Tennyson
- Stephen Carroll
- Stephen Gilles
- Steven Shavell
- Steven Shavell
- Steven Shavell
- Steven Shavell
- Tom
- Tom &
- Tom Baker
- Tom Baker
- Tom Baker
- Tom Baker
- Tom Baker
- Tom Baker
- Tom Baker
- Tom Baker
- Tom Baker
- Tom Baker
- Victor P Goldberg
- Publication venue
- 'Elsevier BV'
- Publication date
- 01/01/2011
- Field of study
Evaluation of appendicitis risk prediction models in adults with suspected appendicitis
- Author
- Abbas Sh
- Abbas Sh
- Abbassi Oa
- Abbott T
- Abdelgadir Am
- Abdelrahman A
- Abdelrahman M
- Abdelrahman M
- Abdelwahed A
- Abellan M
- Abellán Am
- Abellán Am
- Abulafi M
- Acharya A
- Acosta A
- Adam Me
- Adams Re
- Adegbola So
- Adegbola So
- Adimonye A
- Adnan M
- Afshar S
- Agresta F
- Agua Ia
- Aguayo Jl
- Agudo Ar
- Ahad A
- Ahel J
- Ahern Dp
- Ahmad A
- Ahmed B
- Ahmed G
- Ahmed Os
- Ahmed Os
- Ahmed S
- Ainsworth P
- Ais G
- Ais G
- Aisoni F
- Akbari K
- Akhtar K
- Akinsola O
- Akram F
- Al-Faham Z
- Al-Khafaji N
- Al-Khyatt W
- Al-Musawi S
- Al-Sarireh B
- Al-Sheikh M
- Alagna V
- Alani M
- Alberca-Paramo A
- Aldrey I
- Alexander R
- Alhammali T
- Alhammali T
- Ali M
- Aljorfi A
- Allen M
- Allington J
- Alonzo A
- Alshafei A
- Altomare Ma
- Alvarez Cm
- Alvarez E
- Alvarez-Gallego M
- Amaducci E
- Amarasinghe R
- Amayo A
- Ambrona-Zafra D
- Amin V
- Ammendola M
- Amtul N
- Amtul N
- Amuthalingam T
- Anandan L
- Anania G
- Anania M
- Anderson Dj
- Anderson O
- Andolfi E
- Andreani Sm
- Andreani Sm
- Andrews B
- Ang A
- Ang A
- Angelieri D
- Angelini M
- Angrisani M
- Anguita F
- Ansaloni L
- Ansari A
- Aravind B
- Archer Je
- Arcuri Ga
- Arcuri Ga
- Aremu Ma
- Arenal-Vera Jj
- Aresu S
- Aresu S
- Argenio G
- Argenti F
- Armellini A
- Arnau M
- Arredondo J
- Arroyo A
- Arshad F
- Arunachalam S
- Arunachalam S
- Arunachalam S
- Aruparayil N
- Asensio-Gomez L
- Ashmore Dl
- Ashmore Dl
- Ashour O
- Ashraf N
- Asmadi Aa
- Assaf N
- Assaf N
- Assaf N
- Athersmith Mj
- Atzeni J
- Avalapati H
- Avanzolini A
- Avanzolini A
- Awokoya Oo
- Ayllón-Gámez S
- Ayube-Brown J
- Azabdaftari A
- Azevedo J
- Azevedo Jm
- Baddams Ts
- Badenoch T
- Badii B
- Badran A
- Baeza-Murcia M
- Bagga R
- Baginski A
- Bailey Ja
- Bailey S
- Bailey S
- Bailon-Cuadrado M
- Baird C
- Bairos F
- Baker B
- Balai Ej
- Balasubramaniam A
- Balestra F
- Ball A
- Ball A
- Ball A.
- Ballabio M
- Ballester Mm
- Bandyopadhyay Sk
- Banks A
- Bansal H
- Baraghini M
- Barbosa L
- Barker T
- Barker T
- Barnieh W
- Baronio G
- Baronio G
- Barrie A
- Barter Ca
- Bartoli A
- Bascuas-Rodrigo B
- Baseggio M
- Bastianpillai J
- Bawa S
- Baz-Figueroa C
- Bazán-Hinojo Mc
- Bazán-Hinojo Mc
- Beasley Wd
- Bedoya S
- Beggs A
- Bell Cr
- Bell J
- Bellochi R
- Beltran-De-Heredia J
- Beltran-De-Heredia J
- Belvedere A
- Benevento A
- Bennett Jm
- Beral D
- Beral D
- Bernal-Sprekelsen Jc
- Berry B
- Berti S
- Bevan Ke
- Bevan V
- Beverstock A
- Bhanderi S
- Bhanderi S
- Bhanderi S
- Bhanderi S
- Bhanderi S.
- Bhangu A. Nepogodiev D
- Bhangu A
- Bhangu A
- Bhangu A
- Bhangu A
- Bhargava A
- Biancafarina A
- Biancafarina A
- Bianchi Cl
- Bianchi Cl
- Bianco A
- Bilku D
- Birindelli A
- Birindelli A
- Birindelli A
- Blackford Od
- Blackwell J
- Blake L
- Blanco F
- Blanco-Colino R
- Blanco-Colino R
- Blanco-Colino R
- Blanco-Colino R
- Blanco-Colino R.
- Blazeby Jm
- Blencowe N. S.
- Blencowe Ns
- Blencowe Ns
- Blencowe Ns
- Blencowe Ns
- Boddy Ap
- Boereboom C
- Bogdan M
- Bohra P
- Boland M
- Boland M
- Bolger Jc
- Bolger Jc
- Bolton W
- Bolzon S
- Bond S
- Bond-Smith G
- Bondurri A
- Bonfante P
- Bonomo M
- Borg Cm
- Borges Fc
- Borghi F
- Borghol K
- Boshier Pr
- Botelho P
- Bowen J
- Bowerman H
- Bowley D
- Bowman Cr
- Bowman Cr
- Boyd-Carson H
- Boza K
- Bradshaw Cj
- Branagan G
- Bravo-Gutiérrez Af
- Bravo-Gutiérrez Af
- Brennan S
- Brett M
- Brewer H
- Brewer Hk
- Brewer Hk
- Brews R
- Brien Jo
- Bronder C
- Brown A
- Brown Ag
- Brown Ce
- Brown Ce
- Brown Ce
- Brown M
- Brown M
- Brown Od
- Brown R
- Bruce Js
- Brunelli Db
- Bryan Es
- Buckley-Jones S
- Bukhari W
- Bull C
- Bullivant Jk
- Burke J
- Burns Km
- Burnside D
- Busuttil A
- Byrne Be
- Byrnes Ck
- Caballero A
- Caldeira Ab
- Caldwell M
- Callan R
- Calussi M
- Calvo H
- Calvo M
- Cameron Fc
- Campagnaro T
- Campagnaro T
- Campbell U
- Campbell Um
- Campbell W
- Cannata G
- Cannavò M
- Cantafio S
- Capelli P
- Carcoforo P
- Carden Ca
- Carder C
- Cardona R
- Cardoso D
- Carlucci M
- Carney K
- Caro A
- Carral-Freire M
- Carrano Fm
- Carrano Fm
- Cartwright H
- Carvalho Lc
- Carvalho N
- Casimiro C
- Castagnoli G
- Castagnoli G
- Caula C
- Caula C
- Cavallo D
- Cavero A
- Cay P
- Ceccarelli G
- Cerdán-Santacruz C
- Cerdán-Santacruz C
- Cerdán-Santacruz C
- Cerdán-Santacruz C
- Cervellera M
- Cesari Mc
- Chalk A
- Chambers B
- Chan D
- Chan T
- Chan Wh
- Chandler Sb
- Chandratreya N
- Chandratreya N
- Chapman J
- Chapman Sj
- Chapple Ks
- Charalabopoulos A
- Charalambous Mp
- Chasty B
- Chatzikonstantinou M
- Chatzikonstantinou M
- Chauhan P
- Chauhan P
- Chauhan P.
- Cheah Wl
- Chean Cs
- Chean Cs
- Checcacci P
- Cheng Sa
- Cheruvu M
- Chessa A
- Chessa A
- Chetta G
- Chetta N
- Chianese G
- Chillitupa Cz
- Chimetto A
- Chin My
- Chishti Ia
- Chitsabesan P
- Chng S
- Choi S
- Chok Sm
- Chok Sm
- Chong B
- Choolani-Bhojwani E
- Choong Jh
- Choong Jh
- Choong Jh
- Chowdhary M
- Chowdhury F
- Chowdhury F
- Choy Ch
- Choy Ch
- Chrastek D
- Christian L
- Christides A
- Christopoulos P
- Chudek D
- Chui K
- Cianchi F
- Cidoncha A
- Cillara N
- Cillara N
- Cillara N
- Cipparrone M
- Cirillo B
- Clark Gl
- Clark S
- Clement Kd
- Clement Kd
- Clements B
- Clements C
- Clements J
- Clements J.
- Clements Ja
- Clements Jd
- Clements Jm
- Clements Jm
- Clements Js
- Clerici F
- Clingan R
- Cloney L
- Clough E
- Coccolini F
- Coccolini F
- Cocorullo G
- Coe Po
- Cohen Ja
- Colangelo E
- Coletta D
- Coletta D
- Coletti M
- Collado-Roura F
- Collier-Wakefield O
- Colombo F
- Colombo F
- Colvin Da
- Colvin Da
- Compagnoni B
- Conci S
- Connelly Tm
- Connor Kl
- Connor Kl
- Connor Mj
- Connor Mj
- Conti D
- Contine Ac
- Contreras Rg
- Contreras-Saiz E
- Cook V
- Cooke F
- Coppola M
- Coratti F
- Corbellini C
- Cordoba E
- Cordoba E
- Cormenzana Ob
- Correia D
- Correia J
- Cortés Gv
- Cosci M
- Cossu F
- Costa Sd
- Costamagna D
- Cotton Ae
- Couch Dg
- Cousins L
- Couso Jr
- Cox M
- Coyle D
- Creasy W
- Cremades P
- Criado Adc
- Crone A
- Crozier J
- Cruccu A
- Cruickshank N
- Cuadrado Mm
- Cucinotta E
- Cuello-Guzmán E
- Cunha P
- Currow C
- Curti R
- Curtis Nj
- Curtis-Martínez C
- Cynthia G
- Cánovas-Moreno G
- D'Ambra L
- D'Amico Fe
- D'Amico Fe
- D'Amico Fe
- D'Auria M
- D'Auria M
- D'Souza N
- Daga O
- Dalmia S
- Dandy R
- Daniels I
- Danquah-Boateng D
- Dar Fa
- Dar Fa
- Dart K
- Das A
- Daureeawoo R
- Davidson Jr
- Davidson S
- Davies Pl
- Davis S
- De Andres U
- De Burgos Cb
- De Chaves-Rodríguez Pg
- De Freitas S
- De Luca E
- De Marchi F
- De Marco P
- De Nardi P
- De Nardi P
- De Nisco C
- De Padua C
- De Prizio M
- De-La-Herranz-Guerrero P
- De-Manzoni-Garberini A
- De-Manzoni-Garberini A
- De-Manzoni-Garberini A
- De-Marchi Ja
- De-Marchi Ja
- De-Soto-Cardenal B
- Dean Ea
- Dean S
- Del Basso C
- Del Pozo E
- Del-Valle-Ruiz Sr
- Delgado-Plasencia Lj
- Delimpalta C
- Delimpalta C
- Delogu D
- Denley S
- Dennison G
- Depalma N
- Deserra A
- Desiderio J
- Devezas V
- Devine Aa
- Dhar M
- Dharamavaram S
- Dhari Aa
- Dhesi S
- Di Cintio A
- Di Franco F
- Di Gioia P
- Di Saverio S
- Di Zitti L
- Diaz A
- Dickson Ea
- Divekar Ga
- Dixon F
- Dobbs S
- Dobson C
- Docherty Ja
- Doherty C
- Dominguez-Sanchez C
- Donaldson G
- Donaldson G
- Donohoe No
- Donohoe No
- Douka E
- Doulias T
- Dova L
- Downey M
- Doyle C
- Doyle C
- Drake T. M.
- Drake Tm
- Drye N
- Du Dt
- Dubois As
- Dubois As
- Dudek Jg
- Dujovne P
- Dujovne P
- Dunning Pg
- Duran-Muñoz-Cruzado Vm.
- Durbacz M
- Dyal A
- Dyson S
- Díaz-Vico T
- Eardley Nj
- Earnshaw L
- Easdon S
- Ebied H
- Echazarreta E
- Edwards Se
- Egan Rj
- Egan Rj
- Eguaras I
- Eiben I
- Eiben Ie
- Eiben P
- El-Masry S
- El-Tayar O
- El-Tayar O
- Elbetti C
- Elgaddal S
- Elia M
- Ellis B
- Elseedawy M
- Elshaer M
- Elshaer M
- Emslie Km
- Engall N
- Engall N
- Engall N
- English Wj
- Ercolani G
- Erdas E
- Erdas E
- Eretta Co
- Escoll-Rufino J
- Escuder J
- Esmail Hd
- Espin-Basany E
- Espin-Basany E
- Espina B
- Espinosa J
- Esteves Mb
- Ettles C
- Evans J
- Evans Jd
- Everden A
- Evoli Le
- Ezerska E
- Fadel M
- Fahmy Se
- Fahmy Se
- Fairfield Cj
- Falaschi F
- Falco N
- Fanibi Bf
- Fareleira A
- Farhan-Alanie M
- Farina V
- Faris Ar
- Farrell Sm
- Farrow Ez
- Farrow Ez
- Farrés R
- Fasuyi Ja
- Faulkner G
- Fawzi F
- Fehervari M
- Feleppa C
- Feliu F
- Feo Cv
- Ferguson N
- Fermiñán A
- Fernandes C
- Fernández Ec
- Fernández Md
- Fernández-Candela A
- Fernández-Martínez D
- Fernández-Martínez D
- Fernández-Martínez D
- Feroci F
- Ferrara F
- Ferrara F
- Ferreira Js
- Ferreira Ms
- Ferrer-Vilela I
- Fijo Lm
- Finch Jg
- Finlayson H
- Finotti E
- Fiore L
- Fiorot A
- Flack T
- Fleming Ta
- Fleres F
- Foers W
- Foley Nm
- Foley Nm
- Fontaine C
- Fontana T
- Fontani A
- Fooks P
- Foppa C
- Forgie A
- Fornasier C
- Fornell-Ariza M
- Forouzanfar A
- Foschi D
- Foster A
- Fox A
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- Franco M
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- Franklin D
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- Frasson M
- Frasson M
- Frasson M.
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- Fueyo J
- Fung E
- Gabbianelli C
- Gaines E
- Gallo G
- Gallo G
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- Gammeri E
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- García M
- García M
- García Na
- García V
- García-Carrero M
- García-Catalá L
- García-Catalá L
- García-Granero A
- García-Granero A
- García-Gutierrez C
- García-Novoa A
- García-Novoa A
- García-Pérez Jm
- García-Rivera Co
- García-Santos E
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- Garg Ag
- Garnham J
- Garrido L
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- Garvin J
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- Gatti M
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- Gee O
- Gemini A
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- Genzor S
- Geretto P
- Ghaffari I
- Ghatorae S
- Ghazala R
- Ghazanfar Ma
- Giaccari S
- Giani I
- Gidwani Al
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- Giraudo G
- Giubilo C
- Giudicissi R
- Giuffrida Mc
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- Gjoni E
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- Glasbey Jc
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- Golda T
- Golder Am
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- Gomes Ap
- Gomez Cj
- Gomez-Carmona Z
- Gomez-Facundo H
- Gomez-Rosado Jc
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- González-Nicolás T
- Gonzálvez-Guardiola P
- Gonçalves D
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- Gopalswamy S
- Gopinath S
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- Gormely R
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- Gosal A
- Govind G
- Gracia-Roman R
- Grandi S
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- Grassia M
- Gravante G
- Graveston J
- Graveston J
- Gray J
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- Grifell Ms
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- Griffith Jp
- Griffiths E
- Griffiths Ea
- Griffiths Np
- Griffiths Np
- Griffiths Sn
- Griggs R
- Grimaldo Eg
- Groppo G
- Grosvenor S
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- Guerra F
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- Guglielmi A
- Guimarães Jm
- Gulamhussein M
- Guliani J
- Gummaraju A
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- Gurung S
- Gusai Gp
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- Hackney L
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- Hagger R
- Haines S
- Hajibandeh S
- Halkias C
- Halmer S
- Hamelmann Rn
- Hanif Z
- Hanley C
- Hann Aj
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- Hanna T
- Hannan E
- Hannay J
- Harder G
- Hardy E
- Harlinska A
- Harper F
- Harries Rl
- Harris G
- Harris Mp
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- Hasan R
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- Haveliwala Z
- Hawkins W
- Hayat Z
- Hayes C
- Hebbar K
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- Henderson L
- Henderson L
- Hernaez A
- Hernandez-Gimenez L
- Hernando A
- Herrod P
- Herrod P
- Herrod P
- Herrod P. J. J.
- Hever P
- Hickey Lm
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- Hicks G
- Hicks G
- Hidalgo-Rosas Jm
- Hill Ad
- Hill Ad
- Hill J
- Hobson Bm
- Hodgson Jm
- Hoff M
- Hollingsworth A
- Hollyman M
- Hollyman M
- Hontoria Ms
- Hook A
- Hornby St
- Hornby St
- Horsfield E
- Howie Ee
- Hraishawi I
- Huang J
- Hudson-Peacock Nj
- Hudson-Peacock Nj
- Hunter I
- Hureibi Ka
- Hureibi Ka
- Hussain A
- Hussain N
- Hussaini Sa
- Hussein A
- Hussein A
- Hutchinson B
- Iannone I
- Ibrahim Y
- Ikram S
- Ilozue T
- Imperatore M
- Inama M
- Inama M
- Infante H
- Iosif E
- Iqbal Mr
- Iqbal Mr
- Irukulla S
- Irwin R
- Isherwood Jd
- Islam N
- Islam S
- Isolani Sm
- Issa E
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- Ivey P
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- Jackson Nj
- Jah S
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- Jamieson Nb
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- Julià D
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- Kamande Iw
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- Kanakala V
- Kannegieser-Bailey M
- Kaptanis S
- Kara A
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- Kaubrys M
- Kaur G
- Kay Oh
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- Keegan R
- Kelly M
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- Khan K
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- Khan S
- Khasria A
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- Kho H
- Kilkenny J
- Kinross J
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- Kirkham En
- Knight B
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- Kosti A
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- Kouli O
- Kouroumpas E
- Krishnamoorthy A
- Krivan S
- Kumar K
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- Kung V
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- Ladwa N
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- Lai Cw
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- Landaluce-Olavarria A
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- Lara Mc
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- Lau E
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- Law Jj
- Lawday S
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- Layman S
- Layton Gr
- Lazzari G
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- Lecky-Thompson L
- Lee Ka
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- Leon C
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- Pata G
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- Patel H
- Patel Mm
- Patel N
- Patel Pk
- Patel Rt
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- Payá-Llorente C
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- Pearce J
- Pearce J
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- Peirce Cb
- Peiris Gb
- Peixoto R
- Peleki A
- Peleki A
- Pellegrino L
- Pellicanò Ga
- Pellicer-Franco E
- Pellino G
- Pento V
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- Perera Mi
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- Perin A
- Pertile D
- Pertile D
- Peña-Barturen C
- Phelan L
- Photiou D
- Pierre R
- Pietrabissa A
- Pigem A
- Pila U
- Pilkington Jp
- Pineño-Flores C
- Pinillos-Somalo A
- Pinkney Td
- Pinkney Td
- Pinkney Td
- Pinna E
- Pino-Perez O
- Pirari Pf
- Pisanu A
- Piu F
- Planellas P
- Plua-Muniz Kt
- Poacher A
- Podda F
- Podda M
- Podda M
- Podda M
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- Pollard H
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- Popova D
- Poudevigne M
- Prats Ma
- Prideaux A
- Prieto-Nieto Mi
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- Pronin S
- Provenza G
- Puerta E
- Pulighe F
- Pullabatla-Venkata Up
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- Quinn Em
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- Rabie Ma
- Rabie Mr
- Radwan Rw
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- Rahman M
- Rahmani Ls
- Rajagopal S
- Rajaram R
- Rajaretnam N
- Rajjoub Y
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- Ramcharan S
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- Ramos Xh
- Ramos-Bernado Mi
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- Ranathunga S
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- Rashid M
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- Ravindran R
- Raymond M
- Raza Ss
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- Redondo-Calvo Fj
- Reese G
- Regina G
- Rehman S
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- Renzi Cr
- Resende Fm
- Rezacova M
- Rezvani S
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- Ridaura N
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- Rodriguez-Lopez M
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- Roncero Ls
- Ronda Rn
- Roomi S
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- Roscio F
- Roscio F
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- Roth N
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- Rudland I
- Ruffolo C
- Rufo E
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- Ruiz-Marín M
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- Rupasinghe Sn
- Rutherford Dg
- Ruzvidzo F
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- Saad M
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- Saavedra-Chacón M
- Saba A
- Sabia D
- Sacco R
- Sacks R
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- Saha A
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- Sahnan K
- Sahnan K
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- Salama Y
- Salamone G
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- Salandini Mc
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- Salim S
- Salva Ab
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- Samuel M
- Sana S
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- Sanchez-Martinez A
- Sancho-Muriel J
- Sandu L
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- Santurro L
- Sanz-Navarro S
- Sarmah P
- Sarmah P
- Sarmah P
- Sarveswaran J
- Sasia D
- Sasia D
- Saunders S
- Savill A
- Savino G
- Savino G
- Savioli F
- Scabini S
- Scabini S
- Scabini S
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- Scanlon K
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- Scialandrone G
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- Serventi F
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- Shah Sm
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- Sooriyamoorthy T
- Soria-Aledo V
- Soria-Aledo V
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- Sparta C
- Spaziani A
- Speake D
- Speake D
- Springate El
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- Stecca T
- Stella M
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- Stevenson R
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- Strachan E
- Strange Ja
- Stubbs Bm
- Stupalkowska W
- Stupalkowska W
- Suarez-Cabrera A
- Suero Ca
- Sultana A
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- Sunter H
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- Symons N
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- Szucs A
- Szucs A
- Sánchez-Cifuentes A
- Sánchez-Fuentes Mn
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- Tabain V
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- Tague Le
- Tahir W
- Tailor K
- Tallon-Aguilar L
- Tallon-Aguilar L
- Tamayo-López Mj
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- Vallve-Bernal M
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- Vescio G
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- Vigorita V
- Vijay V
- Vila-Zarate C
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- Vulcano I
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- Wilkin R
- Wilkin R
- Wilkin R
- Wilkin R. J. W.
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- Williams M
- Williams R
- Williams S
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- Woodrow C
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- Wright Hl
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- Yalamarthi S
- Yang P
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- Yardimci E
- Yasin T
- Yen Sk
- Yeung K
- Yeung K
- Yoganathan S
- Yoong S
- Youssef H
- Yow L
- Yow L
- Zaborowski A
- Zadi Az
- Zalla T
- Zarka Za
- Zarka Za
- Zarog Ma
- Zelazek M
- Zerpa C
- Zhang Ay
- Zhou S
- Zorrilla L
- Zuin M
- Zurleni Tz
- Publication venue
- 'Wiley'
- Publication date
- 01/01/2019
- Field of study
Background
Appendicitis is the most common general surgical emergency worldwide, but its diagnosis remains challenging. The aim of this study was to determine whether existing risk prediction models can reliably identify patients presenting to hospital in the UK with acute right iliac fossa (RIF) pain who are at low risk of appendicitis.
Methods
A systematic search was completed to identify all existing appendicitis risk prediction models. Models were validated using UK data from an international prospective cohort study that captured consecutive patients aged 16–45 years presenting to hospital with acute RIF in March to June 2017. The main outcome was best achievable model specificity (proportion of patients who did not have appendicitis correctly classified as low risk) whilst maintaining a failure rate below 5 per cent (proportion of patients identified as low risk who actually had appendicitis).
Results
Some 5345 patients across 154 UK hospitals were identified, of which two‐thirds (3613 of 5345, 67·6 per cent) were women. Women were more than twice as likely to undergo surgery with removal of a histologically normal appendix (272 of 964, 28·2 per cent) than men (120 of 993, 12·1 per cent) (relative risk 2·33, 95 per cent c.i. 1·92 to 2·84; P < 0·001). Of 15 validated risk prediction models, the Adult Appendicitis Score performed best (cut‐off score 8 or less, specificity 63·1 per cent, failure rate 3·7 per cent). The Appendicitis Inflammatory Response Score performed best for men (cut‐off score 2 or less, specificity 24·7 per cent, failure rate 2·4 per cent).
Conclusion
Women in the UK had a disproportionate risk of admission without surgical intervention and had high rates of normal appendicectomy. Risk prediction models to support shared decision‐making by identifying adults in the UK at low risk of appendicitis were identified
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