100 research outputs found

    Inteligencia emocional y estilos de crianza en padres de familia de una Institución Educativa Inicial de Piura

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    La investigación tuvo como propósito determinar la relación entre la inteligencia emocional y los estilos de crianza en padres de familia de una institución educativa inicial de Piura. El estudio fue de tipo correlacional y de diseño no experimental - transversal. La muestra la conformaron 119 padres de ambos sexos, por muestreo no probabilístico por conveniencia. Para la recolección de los datos se utilizó el Trait MetaMood Scale (TMMS- 24) y la Escala de Comportamiento para madres y padres con niños pequeños (ECMP). Se demostró que existe una relación significativa entre la inteligencia emocional y los estilos de crianza, con un valor X2 de 25,562 y una significación estadística de 0,000.Tesi

    Aplicación móvil para mejorar la gestión de incidencias delictivas en el distrito de Víctor Larco, 2023

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    La presente tesis tiene como objetivo principal de mejorar la gestión de incidencias delictivas. Se realizó un estudio experimental puro teniendo un total de 30 datos como muestra de incidencias delictivas, utilizando la metodología Mobile-D. Como también las herramientas de diseño y codificación Android Studio y Visual Code, además de la base de datos Firebase. Como también los lenguajes de codificación que se usaron como JavaScript, Java, Kotlin, Php .Con los resultados se realizaron pruebas no paramétricas, donde el primer indicador de tiempo promedio de registro se pudo mejorar un 53%, el segundo indicador de tiempo promedio de búsqueda de incidencias donde se pudo mejorar un 63%, el tercer indicador de tiempo promedio de derivación se pudo reducir en un 56%, el cuarto indicador de tiempo de reporte de incidencias se mejoró un 56% y por último el indicador de porcentajes resueltos se pudo mejorar en un 56%.Con estos resultados se pudo comprobar que la implementación de una aplicación móvil para mejorar la gestión de incidencias delictivas dentro de una central de monitoreo, es efectiva y puede tener un impacto positivo en la seguridad ciudadana

    Antioxidant and hypoglycemic effects of watercress (Nasturtium officinale) extracts in diabetic rats

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    Background: Watercress is a semi-aquatic plant used in traditional medicine to treat various ailments, such as flu, cough, avitaminosis, and anorexia; it is also used as a diuretic and for hypoglycemia treatment in diabetes. In this study, we report the antioxidant and hypoglycemic activity of orally administered aqueous (WAQE), acetonic (WAE), and alcoholic (WOHE) watercress extracts. The effect of subchronic administration of watercress extracts on oxidative stress was also studied.Materials and Methods: WAQE, WAE, and WOHE were obtained and administered orally. Alloxan (200 mg/kg) and streptozotocin (60 mg/kg) were applied to induce hyperglycemia in male Wistar rats. Phenolic and flavonoid content, as well as antioxidant activity of the extracts were measured. The acute and subchronic effects (8 weeks) of WAQE were evaluated. The activity of antioxidant enzymes levels of malondialdehyde, hepatic enzyme markers in the serum, and renal function markers, were assessed. Histopathological evaluation of the pancreas, kidney, and liver was performed using hematoxylin-eosin staining.Results: Watercress extracts have high concentrations of phenols, polyphenols, and flavonoids, in addition to a very high antioxidant effect. The hypoglycemic effect of WAQE upon acute administration was 76.6% higher than that of insulin. When administered chronically, glucose levels were normalized on the third week up to the eighth week. Furthermore, the antioxidant enzymes and biochemical parameters improved.Conclusion: WAQE administration to diabetic rats reduced oxidative stress damage and decreased glucose levels. This study supports the use of this plant for the treatment of diabetes.Keywords: Antioxidant, Diabetes, Watercress (Nasturtium officinale), Oxidative stress, Pancrea

    Respuestas funcionales de Novius punicus (Gordon) y Novius cardinalis (Mulsant) (Coleoptera: Coccinellidae) a Crypticerya multicicatrices Kondo and Unruh (Hemiptera: Monophlebidae)

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    The functional responses of Novius punicus (Gordon) and N. cardinalis (Mulsant) (Coleoptera: Coccinellidae) were investigated using eggs and first-instar nymphs of Crypticerya multicicatrices Kondo and Unruh (Hemiptera: Monophlebidae), respectively, as prey. Ten-day-old laboratory-reared adult individuals of each coccinellid species were placed individually in Petri dishes, and each one was offered a different prey density for a 24-hour period. For N. cardinalis, prey densities of 10, 20, 50, 100, and 150 first-instar nymphs of C. multicicatrices were evaluated. With N. punicus, densities of 10, 25, 50, 100, and 200 eggs of the fluted scale were evaluated. Using the proportion of prey consumed, a logistic regression was performed, which allowed the identification of the type of functional response described by the data. The random predator equation was then used to describe the functional response, using the R software v. 3.4.1. For the two species of coccinellids, a type II functional response was found, which describes a decrease in the proportion of prey consumed as the density of the prey increases. The estimated parameters of the random predator equation, attack rate (α) and handling time (in hours) (Th) were as follows: N. punicus: α = 0.12, Th = 0.64; N. cardinalis: α = 0.05; Th = 0.34. These results represent an advance in the evaluation of the potential of these predators to be used in a pest management program for C. multicicatrices.El objetivo de este trabajo fue determinar la respuesta funcional de Novius punicus (Gordon) y N. cardinalis (Mulsant) (Coleoptera: Coccinellidae) utilizando, como presa, huevos y ninfas del primer estadio de Crypticerya multicicatrices Kondo and Unruh (Hemiptera: Monophlebidae), respectivamente. Se individualizaron, en cajas Petri, especímenes adultos de 10 días de edad de cada especie de coccinélido, criados en laboratorio, y a cada uno se le ofreció por un periodo de 24 horas una densidad de presa diferente. Para N. cardinalis, se evaluaron las densidades de presa de 10, 20, 50, 100 y 150 ninfas del primer estadio de C. multicicatrices. Con N. punicus se evaluaron densidades de 10, 25, 50, 100 y 200 huevos de esta cochinilla acanalada. Con la proporción de presas consumidas se realizó una regresión logística, que permitió identificar la forma de la respuesta funcional que describen los datos. Se utilizó la ecuación de depredador aleatorio para la descripción de la respuesta funcional, mediante el uso del software R v. 3.4.1. Para las dos especies de coccinélidos se encontró una respuesta funcional tipo II, la cual describe una disminución en la proporción de presas consumidas a medida que la densidad de la presa incrementa. Los parámetros estimados de la ecuación del depredador aleatorio, tasa de ataque (α) y tiempo de manipulación (en horas) (Th) fueron los siguientes: N. punicus: α = 0.12, Th= 0.64; N. cardinalis: α = 0.05; Th = 0.34. Estos resultados representan un avance en la evaluación del potencial que tienen estos depredadores para usarse en un programa de manejo de plagas para C. multicicatrices

    ANTIOXIDANT AND HYPOGLYCEMIC EFFECTS OF WATERCRESS (NASTURTIUM OFFICINALE) EXTRACTS IN DIABETIC RATS

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    Background: Watercress is a semi-aquatic plant used in traditional medicine to treat various ailments, such as flu, cough, avitaminosis, and anorexia; it is also used as a diuretic and for hypoglycemia treatment in diabetes. In this study, we report the antioxidant and hypoglycemic activity of orally administered aqueous (WAQE), acetonic (WAE), and alcoholic (WOHE) watercress extracts. The effect of subchronic administration of watercress extracts on oxidative stress was also studied. Materials and Methods: WAQE, WAE, and WOHE were obtained and administered orally. Alloxan (200 mg/kg) and streptozotocin (60 mg/kg) were applied to induce hyperglycemia in male Wistar rats. Phenolic and flavonoid content, as well as antioxidant activity of the extracts were measured. The acute and subchronic effects (8 weeks) of WAQE were evaluated. The activity of antioxidant enzymes levels of malondialdehyde, hepatic enzyme markers in the serum, and renal function markers, were assessed. Histopathological evaluation of the pancreas, kidney, and liver was performed using hematoxylin-eosin staining. Results: Watercress extracts have high concentrations of phenols, polyphenols, and flavonoids, in addition to a very high antioxidant effect. The hypoglycemic effect of WAQE upon acute administration was 76.6% higher than that of insulin. When administered chronically, glucose levels were normalized on the third week up to the eighth week. Furthermore, the antioxidant enzymes and biochemical parameters improved. Conclusion: WAQE administration to diabetic rats reduced oxidative stress damage and decreased glucose levels. This study supports the use of this plant for the treatment of diabetes

    Study and prevalence of post-transplant diabetes mellitus; analysis on a group of kidney transplant recipients

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    Introducción: La aparición de la diabetes mellitus pos - trasplante (DMPT) entre los receptores renales se asocia con un mayor riesgo de fracaso del injerto y altas tasas de morbimortalidad. Minimizar el riesgo de DMPT es una prioridad para la mejora a largo plazo de las tasas de su - pervivencia. Objetivos: Este estudio tiene como objetivo evaluar la prevalencia de DMPT en una población de paciente tras - plantados renales, para identificar los factores de riesgo y evaluar el injerto y supervivencia de los pacientes. Métodos: La muestras estuvo formada por 112 pacientes trasplantados renales, 69 hombres y 43 mujeres, trasplan - tados renales, que asistieron durante cinco años a la con - sulta postrasplante. Se analizaron como posibles factores de riesgo para DMPT: edad, sexo, índice de masa corporal (IMC), sobrepeso, hepatitis C, hipertensión, dislipemia, co - lesterol total (CT), triglicéridos en suero y terapia inmuno - supresora (Ciclosporina, tacrolimus, micofenolato mofetil y sirolimus), también se evaluó la prevalencia de episodios de rechazo agudo. Resultados: La prevalencia de PTDM fue del 24,2%, frente a 85 pacientes (75,8%) con glucosa normalizada (PGN). Los pacientes con DMPT mostraron un IMC ma - yor, un porcentaje mayor de sobrepeso, dislipemias, niveles colesterol total, triglicéridos y se presento un mayor por - centaje de pacientes con PDMPT entre los que se adminis - traron Micofenolato mofetil. Conclusiones: Existe una alta incidencia de DMPT en receptores renales, la importancia del control de peso y de un seguimiento estricto para todos los factores de riesgo identificados, asi como una minimización en las dosis de tratamientos inmunosupresores para prevenir la aparición de DMPT.Introduction: The onset of post-transplant diabetes mellitus (PTDM) among kidney recipients is associated with an increased risk of graft failure and high rates of morbidity and mortality. Minimize the risk of PTDM is a priority for improving long-term survival rates. Aims. This study aims to assess the prevalence of PTDM in a re - nal transplant patient population, to identify risk factors and assess the graft and patient survival. Methods: The sample consisted of 112 renal transplant patients , 69 men and 43 women , renal transplant , who attended for five years post-transplant consultation. Were analyzed as potential risk factors for PTDM : age , sex, body mass index (BMI ) , obesity , VHC , hyperten - sion, dyslipidemia , total cholesterol (TC) , serum trigly - ceride and immunosuppressive therapy ( cyclosporine , tacrolimus , mycophenolate mofetil and sirolimus ), also the prevalence of acute rejection episodes was evaluated. Results: The prevalence of PTDM was 24.2 %, com - pared with 85 patients (75.8%) with standard glucose (PGN) . PTDM patients showed a higher BMI , a higher percentage of overweight , dyslipidemia , total cholesterol levels , triglycerides and performed a greater percentage of patients with PDMPT including Mycophenolate mofe - til was administered. Conclusions: There is a high incidence of PTDM in kidney recipients , the importance of weight control and strict adherence to all identified risk factors , as well as in minimizing the doses of immunosuppressive therapies to prevent the onset of PTDM

    Exploring the Diversity of Plant DNA Viruses and Their Satellites Using Vector-Enabled Metagenomics on Whiteflies

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    Current knowledge of plant virus diversity is biased towards agents of visible and economically important diseases. Less is known about viruses that have not caused major diseases in crops, or viruses from native vegetation, which are a reservoir of biodiversity that can contribute to viral emergence. Discovery of these plant viruses is hindered by the traditional approach of sampling individual symptomatic plants. Since many damaging plant viruses are transmitted by insect vectors, we have developed “vector-enabled metagenomics” (VEM) to investigate the diversity of plant viruses. VEM involves sampling of insect vectors (in this case, whiteflies) from plants, followed by purification of viral particles and metagenomic sequencing. The VEM approach exploits the natural ability of highly mobile adult whiteflies to integrate viruses from many plants over time and space, and leverages the capability of metagenomics for discovering novel viruses. This study utilized VEM to describe the DNA viral community from whiteflies (Bemisia tabaci) collected from two important agricultural regions in Florida, USA. VEM successfully characterized the active and abundant viruses that produce disease symptoms in crops, as well as the less abundant viruses infecting adjacent native vegetation. PCR assays designed from the metagenomic sequences enabled the complete sequencing of four novel begomovirus genome components, as well as the first discovery of plant virus satellites in North America. One of the novel begomoviruses was subsequently identified in symptomatic Chenopodium ambrosiodes from the same field site, validating VEM as an effective method for proactive monitoring of plant viruses without a priori knowledge of the pathogens. This study demonstrates the power of VEM for describing the circulating viral community in a given region, which will enhance our understanding of plant viral diversity, and facilitate emerging plant virus surveillance and management of viral diseases

    Why Are Outcomes Different for Registry Patients Enrolled Prospectively and Retrospectively? Insights from the Global Anticoagulant Registry in the FIELD-Atrial Fibrillation (GARFIELD-AF).

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    Background: Retrospective and prospective observational studies are designed to reflect real-world evidence on clinical practice, but can yield conflicting results. The GARFIELD-AF Registry includes both methods of enrolment and allows analysis of differences in patient characteristics and outcomes that may result. Methods and Results: Patients with atrial fibrillation (AF) and ≥1 risk factor for stroke at diagnosis of AF were recruited either retrospectively (n = 5069) or prospectively (n = 5501) from 19 countries and then followed prospectively. The retrospectively enrolled cohort comprised patients with established AF (for a least 6, and up to 24 months before enrolment), who were identified retrospectively (and baseline and partial follow-up data were collected from the emedical records) and then followed prospectively between 0-18 months (such that the total time of follow-up was 24 months; data collection Dec-2009 and Oct-2010). In the prospectively enrolled cohort, patients with newly diagnosed AF (≤6 weeks after diagnosis) were recruited between Mar-2010 and Oct-2011 and were followed for 24 months after enrolment. Differences between the cohorts were observed in clinical characteristics, including type of AF, stroke prevention strategies, and event rates. More patients in the retrospectively identified cohort received vitamin K antagonists (62.1% vs. 53.2%) and fewer received non-vitamin K oral anticoagulants (1.8% vs . 4.2%). All-cause mortality rates per 100 person-years during the prospective follow-up (starting the first study visit up to 1 year) were significantly lower in the retrospective than prospectively identified cohort (3.04 [95% CI 2.51 to 3.67] vs . 4.05 [95% CI 3.53 to 4.63]; p = 0.016). Conclusions: Interpretations of data from registries that aim to evaluate the characteristics and outcomes of patients with AF must take account of differences in registry design and the impact of recall bias and survivorship bias that is incurred with retrospective enrolment. Clinical Trial Registration: - URL: http://www.clinicaltrials.gov . Unique identifier for GARFIELD-AF (NCT01090362)

    Risk profiles and one-year outcomes of patients with newly diagnosed atrial fibrillation in India: Insights from the GARFIELD-AF Registry.

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    BACKGROUND: The Global Anticoagulant Registry in the FIELD-Atrial Fibrillation (GARFIELD-AF) is an ongoing prospective noninterventional registry, which is providing important information on the baseline characteristics, treatment patterns, and 1-year outcomes in patients with newly diagnosed non-valvular atrial fibrillation (NVAF). This report describes data from Indian patients recruited in this registry. METHODS AND RESULTS: A total of 52,014 patients with newly diagnosed AF were enrolled globally; of these, 1388 patients were recruited from 26 sites within India (2012-2016). In India, the mean age was 65.8 years at diagnosis of NVAF. Hypertension was the most prevalent risk factor for AF, present in 68.5% of patients from India and in 76.3% of patients globally (P < 0.001). Diabetes and coronary artery disease (CAD) were prevalent in 36.2% and 28.1% of patients as compared with global prevalence of 22.2% and 21.6%, respectively (P < 0.001 for both). Antiplatelet therapy was the most common antithrombotic treatment in India. With increasing stroke risk, however, patients were more likely to receive oral anticoagulant therapy [mainly vitamin K antagonist (VKA)], but average international normalized ratio (INR) was lower among Indian patients [median INR value 1.6 (interquartile range {IQR}: 1.3-2.3) versus 2.3 (IQR 1.8-2.8) (P < 0.001)]. Compared with other countries, patients from India had markedly higher rates of all-cause mortality [7.68 per 100 person-years (95% confidence interval 6.32-9.35) vs 4.34 (4.16-4.53), P < 0.0001], while rates of stroke/systemic embolism and major bleeding were lower after 1 year of follow-up. CONCLUSION: Compared to previously published registries from India, the GARFIELD-AF registry describes clinical profiles and outcomes in Indian patients with AF of a different etiology. The registry data show that compared to the rest of the world, Indian AF patients are younger in age and have more diabetes and CAD. Patients with a higher stroke risk are more likely to receive anticoagulation therapy with VKA but are underdosed compared with the global average in the GARFIELD-AF. CLINICAL TRIAL REGISTRATION-URL: http://www.clinicaltrials.gov. Unique identifier: NCT01090362
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