La filosofía de Julio Ramón Ribeyro en Prosas apátridas y Dichos de Luder: entre el escepticismo y el pesimismo.

En la presente tesis establezco una lectura desde la filosofía de Prosas Apátridas y Dichos de Luder, obras escritas por Julio Ramón Ribeyro. Propongo que ambos libros traslucen una mirada escéptica y pesimista, que además recorre toda la producción de Ribeyro. El escepticismo está presente desde la forma fragmentaria de los textos, que refleja la visión que Ribeyro tiene de la realidad: múltiple y contradictoria. Asimismo, el escepticismo de Ribeyro está emparentado con la versión de la antigüedad, cuyo énfasis es práctico, y se basa en la imposibilidad de decidir entre opciones y sensaciones contrapuestas para encontrar la verdad. En este sentido, resulta provechoso comentar su escepticismo desde los planteamientos de Sexto Empírico y Montaigne. Por otro lado, tanto en Prosas Apátridas como en Dichos de Luder hay una visión pesimista, que se fundamenta en la discrepancia entre las aspiraciones humanas y sus nulas posibilidades de realización. Ribeyro hace hincapié en la inestabilidad que el paso del tiempo trae consigo para los seres humanos y también hace referencia al tópico de la muerte: destino compartido que matiza todos los afanes humanos. Finalmente, explico como el malestar que Ribeyro manifiesta en ambas obras, se puede explicar mediante los conceptos del absurdo y el ennui

Produção de carne nos trópicos secos de Tamaulipas, México: cruzamento de Bos taurus e Bos indicus

The objective of this study was evaluated the productive performance in Charolais (CH), Simmental (SM) and Braunvieh (BR) sires and Zebu, (ZE), Suiss (SU) x ZE and CH x ZE dams, among birth and weaning calves weights. The environment is dry tropical with summer rains. The livestock grassing in a introducing grasses Star grass (Cynodon nlemfuensis) y Guinea (Panicum maximun). The reproduction was artificial insemination with CH, SM and BR semen and natural insemination with CH sires after insemination. The calves were identificated at birth with the mother number and were weighted in the first 24 ours. The data were analyzed with minimum squares method to determinate, season (SE), calf sex (SX) and dam age (DE). The average for birth weight (BW) was 34.6 kg and only the SE were statistical significant (P < 0.05) for this characteristic. For weaning weight (WW) the mean was 165.7 kg and SE and DE and were statistical significant (P < 0.05). The conclusion is that the environmental effects in this study was more important than genetics effects both BW and WW variables.El objetivo del presente estudio fue evaluar la productividad de toros Charoláis (CH), Simmental (SM) y Pardo Suizo (PS) con vacas Cebú (CE), PS x CE y CH x CE a través del peso al nacimiento y al destete de los becerros. El rancho contaba con praderas de Estrella de África (Cynodon nlemfuensis) y Guinea (Panicum maximun), utilizadas con pastoreo rotacional. La reproducción de las vacas fue a través de inseminación artificial con semen de SM, CH y PS y fueron repasadas por toros CH. Los becerros fueron tatuados en la oreja con el número de la madre y se pesaron en las primeras 24 h después del nacimiento. Los datos fueron analizados por el método de cuadrados mínimos para determinar los efectos de año (AN) y estación de nacimiento (EN), sexo de la cría (SX) y edad de la vaca (EV). La media general para peso al nacimiento fue 34.6 kg, solo los efectos de AN y EN influenciaron (P < 0.05) el peso al nacimiento. El mayor peso se observó en los becerros nacidos en 1994 durante la época de lluvias. Para el caso del PD la media fue de 165.7 kg, los efectos de AN, EN, EV y la correlación de AN x EN fueron estadísticamente significativos (P < 0.05), donde los mayores pesos fueron de los becerros nacidos en el año 1994 durante la época de sequía. Se puede concluir que en este trabajo los factores medioambientales fueron más importantes que los factores genéticos para ambas variables.Resumo. O objetivo deste trabalho foi avaliar a produtividade de touros Charolês (CH), Simental (SM) e Pardo Suíço (PS) com vacas Zebu (CE), PS x CE e CH x CE através dos pesos ao nascimento e à desmama dos bezerros. A fazenda possuía pastagens African Star (Cynodon nlemfuensis) e Guinea (Panicum maximun), utilizadas com pastejo rotacionado. As vacas foram cruzadas por inseminação artificial com sêmen de SM, CH e PS e foram cruzadas com touros CH. Os bezerros foram tatuados na orelha com o número da mãe e pesados nas primeiras 24 horas após o nascimento. Os dados foram analisados pelo método dos mínimos quadrados para determinar os efeitos da estação de nascimento (EN), sexo do bezerro (SX) e idade da vaca (EV). A média geral para os pesos ao desmame dos bezerros foi de 34,6 kg, apenas os efeitos da EN influenciaram (P < 0,05) o peso ao nascer. Os maiores pesos foram observados nos bezerros nascidos na estação chuvosa. Para PD a média foi de 165,7 kg, os efeitos de EN e EV foram estatisticamente significativos (P < 0,05), onde os maiores pesos foram dos bezerros nascidos na estação seca. Pode-se concluir que neste trabalho os fatores ambientais foram mais importantes que os fatores genéticos para ambas as variáveis

Comportamiento productivo de corderas de diferente genotipo bajo un sistema de engorda intensivo

El objetivo fue evaluar el efecto del genotipo de las corderas sobre la finalización en corral en las condiciones del noroeste de la provincia de Corrientes, Argentina. El experimento se realizó en la Estación Experimental Agropecuaria (EEA) del Instituto Nacional de Tecnología Agropecuaria (INTA) Corrientes, Argentina. Se utilizaron 30 corderas [12 = Santa Inés (SI = pelo); 12 cruzadas Dorper x Romney (DR = pelo-lana); y 6 = Criollas (CR = lana)], con un promedio de peso vivo de 20,1 kg, distribuidas en cinco corrales. Las corderas recibieron una dieta basada en 40% expeler de girasol – 60% grano de maíz entero y la fibra fue aportada por heno de zacate Rhodes. Además, tuvieron libre acceso al agua y sal mineral. Se utilizó un diseño completamente al azar donde el genotipo de las corderas fue la variable independiente. Se estudió la ganancia diaria de peso vivo (GDPV), la ganancia total de peso vivo (GTPV), el consumo de alimento diario por corral (CDC) y la conversión alimenticia (CAC) por corral. Los grupos raciales presentaron diferencias significativas (P<0,05) en GDPV, GTPV, CDC y CAC. Las medias generales fueron 0,14 kg.día-1, 9,62 kg, 7,19 kg MS.día-1y 8,62 kg MS.kg carne-1para GDPV, GTPV, CDC y CAC, respectivamente. Se concluye que los genotipos de pelo (SI y DR) fueron más eficientes.The objective was to evaluate the effect of the genotype of lambs on the stockyard finalization in the Northwest of the province of Corrientes, Argentina conditions. The experiment was carried out at the Experimental Station Farming (EEA) of the Institute National Agricultural Technology (INTA) Corrientes, Argentina. Used 30 lambs (Santa Inés = 12; Dorper x Romney = 12; and Creole = 6), with an average live weight of 20,1 kg, distributed in five pens. The lambs received a diet based on 40% expel sunflower -60% whole corn grain and fiber was provided by Rhodes grass hay. In addition, they had water and mineral salt ad libitum. We used a completely randomized design; we studied daily gain of live weight (GDPV), the total gain of live weight (GTPV), daily consumption by pen (CDC) and feed conversion (CAC) for pen. The genotypes were significantly different (P<0,05) in GDPV, GTPV, CDC and CAC. The average general were 0,14 kg.day-1, 9,62 kg, 7,19 kg MS-1and 8,62 kg MS.meat-1kg for GDPV, GTPV, CDC, and CAC, respectively. It is concluded that hair breeds (SI and DR) were more efficient.EEA CorrientesFil: Cardozo, Julio César. Universidad Nacional del Nordeste. Facultad de Ciencias Agrarias; ArgentinaFil: Verdoljak, Juan Jose. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Corrientes; ArgentinaFil: Martínez-González, Juan Carlos. Universidad Autónoma de Tamaulipas. Facultad de Ingeniería y Ciencias; MéxicoFil: Castillo-Rodríguez, Sonia Patricia. Universidad Autónoma de Tamaulipas. Facultad de Ingeniería y Ciencias; MéxicoFil: Hernández-Meléndez, Javier. Universidad Autónoma de Tamaulipas. Facultad de Ingeniería y Ciencias; MéxicoFil: Parra-Bracamonte, Gaspar Manuel. Instituto Politécnico Nacional. Centro de Biotecnología Genómica; Méxic

Treatment with tocilizumab or corticosteroids for COVID-19 patients with hyperinflammatory state: a multicentre cohort study (SAM-COVID-19)

Objectives: The objective of this study was to estimate the association between tocilizumab or corticosteroids and the risk of intubation or death in patients with coronavirus disease 19 (COVID-19) with a hyperinflammatory state according to clinical and laboratory parameters. Methods: A cohort study was performed in 60 Spanish hospitals including 778 patients with COVID-19 and clinical and laboratory data indicative of a hyperinflammatory state. Treatment was mainly with tocilizumab, an intermediate-high dose of corticosteroids (IHDC), a pulse dose of corticosteroids (PDC), combination therapy, or no treatment. Primary outcome was intubation or death; follow-up was 21 days. Propensity score-adjusted estimations using Cox regression (logistic regression if needed) were calculated. Propensity scores were used as confounders, matching variables and for the inverse probability of treatment weights (IPTWs). Results: In all, 88, 117, 78 and 151 patients treated with tocilizumab, IHDC, PDC, and combination therapy, respectively, were compared with 344 untreated patients. The primary endpoint occurred in 10 (11.4%), 27 (23.1%), 12 (15.4%), 40 (25.6%) and 69 (21.1%), respectively. The IPTW-based hazard ratios (odds ratio for combination therapy) for the primary endpoint were 0.32 (95%CI 0.22-0.47; p < 0.001) for tocilizumab, 0.82 (0.71-1.30; p 0.82) for IHDC, 0.61 (0.43-0.86; p 0.006) for PDC, and 1.17 (0.86-1.58; p 0.30) for combination therapy. Other applications of the propensity score provided similar results, but were not significant for PDC. Tocilizumab was also associated with lower hazard of death alone in IPTW analysis (0.07; 0.02-0.17; p < 0.001). Conclusions: Tocilizumab might be useful in COVID-19 patients with a hyperinflammatory state and should be prioritized for randomized trials in this situatio

75 años como referente de la investigación agraria y medioambiental española en condiciones de clima mediterráneo [Sitio Web]

1 .pdf con imagen de acceso al “website”, su url y los créditos relacionados con su creación y diseño.-- Créditos: Organización, Estación Experimental de Aula Dei (EEAD-CSIC); Dirección, Jesús Val Falcón; Coordinación, Ana Álvarez-Fernandez, Jorge Álvaro-Fuentes, Ernesto Igartua; Contenido, Anunciación Abadía, Javier Abadía, Carlos Albiñana, Miguel Alfonso, Arancha Arbeloa, Raúl Arbués, Isabel Armillas, Manuel Becana, Santiago Beguería, Carmen Castañeda, Ana Castillo, José Cavero, Bruno Contreras, Azahara Díaz, Edgar García, Elena García, Juan Manuel Gascuñana, Leticia Gaspar, Yolanda Gogorcena, Juan Herrero, Victoria Lafuente, María Victoria López, Juan Antonio Marín, José Martínez, José Carlos Martínez-Giménez, Ana Pilar Mata, Manuel Matamoros, Pierre Mignard, María Ángeles Moreno, Paula Murillo, Ana Navas, Antonio Pérez, Rafael Picorel, María Pilar Vallés, Irene Villar, Inmaculada Yruela, Nery Zapata, Isabel Zarazaga; Diseño y programación: DigitalWorks (Juanjo Ascaso y Asun Dieste); Vídeo, Delegación del CSIC en Aragón (Sara Gutiérrez y Yolanda Hernáiz); Fotografía, Archivo EEAD-CSIC, Anunciación Abadía, Jorge Álvaro-Fuentes, Arancha Arbeloa, Juanjo Ascaso, Santiago Beguería, Elena García, Ernesto Igartua, Ignasi Iglesias, José Manuel Lasa, José Carlos Martínez-Giménez, Pierre Mignard, María Ángeles Moreno, Rubén Sancho, Kosana Suvocarev, María Pilar Vallés, Nery Zapata."Sitio web" de nueva creación y conmemorativo del 75 Aniversario de la EEAD-CSIC que contiene: 1) Foto esférica de su personal en activo; 2) Recopilación de sus hitos históricos más destacados, en orden cronológico; 3) Un vídeo con participación de su personal y muestra de algunas de sus instalaciones; 4) Un mapa con la distribución geográfica de los egresado del Instituto; 5) Algunas fotos, destacando las tomadas a su personal en las celebraciones del 25 y 50 Aniversarios de la EEAD-CSIC.Presentado durante la "Jornada. 75 Aniversario EEAD-CSIC (Zaragoza, Patio de la Infanta. 30 octubre 2019)".Financiación: CSIC, Vicepresidencia Adjunta de Organización y Cultura Científica.N

Les droits disciplinaires des fonctions publiques : « unification », « harmonisation » ou « distanciation ». A propos de la loi du 26 avril 2016 relative à la déontologie et aux droits et obligations des fonctionnaires

The production of tt‾ , W+bb‾ and W+cc‾ is studied in the forward region of proton–proton collisions collected at a centre-of-mass energy of 8 TeV by the LHCb experiment, corresponding to an integrated luminosity of 1.98±0.02 fb−1 . The W bosons are reconstructed in the decays W→ℓν , where ℓ denotes muon or electron, while the b and c quarks are reconstructed as jets. All measured cross-sections are in agreement with next-to-leading-order Standard Model predictions.The production of $t\overline{t}$, $W+b\overline{b}$ and $W+c\overline{c}$ is studied in the forward region of proton-proton collisions collected at a centre-of-mass energy of 8 TeV by the LHCb experiment, corresponding to an integrated luminosity of 1.98 $\pm$ 0.02 \mbox{fb}^{-1}. The $W$ bosons are reconstructed in the decays $W\rightarrow\ell\nu$, where $\ell$ denotes muon or electron, while the $b$ and $c$ quarks are reconstructed as jets. All measured cross-sections are in agreement with next-to-leading-order Standard Model predictions

Robust estimation of bacterial cell count from optical density

Optical density (OD) is widely used to estimate the density of cells in liquid culture, but cannot be compared between instruments without a standardized calibration protocol and is challenging to relate to actual cell count. We address this with an interlaboratory study comparing three simple, low-cost, and highly accessible OD calibration protocols across 244 laboratories, applied to eight strains of constitutive GFP-expressing E. coli. Based on our results, we recommend calibrating OD to estimated cell count using serial dilution of silica microspheres, which produces highly precise calibration (95.5% of residuals &lt;1.2-fold), is easily assessed for quality control, also assesses instrument effective linear range, and can be combined with fluorescence calibration to obtain units of Molecules of Equivalent Fluorescein (MEFL) per cell, allowing direct comparison and data fusion with flow cytometry measurements: in our study, fluorescence per cell measurements showed only a 1.07-fold mean difference between plate reader and flow cytometry data

Measurement of the (eta c)(1S) production cross-section in proton-proton collisions via the decay (eta c)(1S) -&gt; p(p)over-bar

The production of the $\eta_c (1S)$ state in proton-proton collisions is probed via its decay to the $p \bar{p}$ final state with the LHCb detector, in the rapidity range $2.0 6.5$ GeV/c. The cross-section for prompt production of $\eta_c (1S)$ mesons relative to the prompt $J/\psi$ cross-section is measured, for the first time, to be $\sigma_{\eta_c (1S)}/\sigma_{J/\psi} = 1.74 \pm 0.29 \pm 0.28 \pm 0.18 _{B}$ at a centre-of-mass energy $\sqrt{s} = 7$ TeV using data corresponding to an integrated luminosity of 0.7 fb$^{-1}$, and $\sigma_{\eta_c (1S)}/\sigma_{J/\psi} = 1.60 \pm 0.29 \pm 0.25 \pm 0.17 _{B}$ at $\sqrt{s} = 8$ TeV using 2.0 fb$^{-1}$. The uncertainties quoted are, in order, statistical, systematic, and that on the ratio of branching fractions of the $\eta_c (1S)$ and $J/\psi$ decays to the $p \bar{p}$ final state. In addition, the inclusive branching fraction of $b$-hadron decays into $\eta_c (1S)$ mesons is measured, for the first time, to be $B ( b \rightarrow \eta_c X ) = (4.88 \pm 0.64 \pm 0.25 \pm 0.67 _{B}) \times 10^{-3}$, where the third uncertainty includes also the uncertainty on the $J/\psi$ inclusive branching fraction from $b$-hadron decays. The difference between the $J/\psi$ and $\eta_c (1S)$ meson masses is determined to be $114.7 \pm 1.5 \pm 0.1$ MeV/c$^2$.The production of the $\eta _c (1S)$ state in proton-proton collisions is probed via its decay to the $p\overline{p}$ final state with the LHCb detector, in the rapidity range $2.0 6.5 \mathrm{{\,GeV/}{ c}}$ . The cross-section for prompt production of $\eta _c (1S)$ mesons relative to the prompt ${{ J}}/{\psi }$ cross-section is measured, for the first time, to be $\sigma _{\eta _c (1S)}/\sigma _{{{{ J}}/{\psi }}} = 1.74\, \pm \,0.29\, \pm \, 0.28\, \pm \,0.18 _{{\mathcal{B}}}$ at a centre-of-mass energy ${\sqrt{s}} = 7 {~\mathrm{TeV}}$ using data corresponding to an integrated luminosity of 0.7 fb$^{-1}$ , and $\sigma _{\eta _c (1S)}/\sigma _{{{{ J}}/{\psi }}} = 1.60 \pm 0.29 \pm 0.25 \pm 0.17 _{{\mathcal{B}}}$ at ${\sqrt{s}} = 8 {~\mathrm{TeV}}$ using 2.0 fb$^{-1}$ . The uncertainties quoted are, in order, statistical, systematic, and that on the ratio of branching fractions of the $\eta _c (1S)$ and ${{ J}}/{\psi }$ decays to the $p\overline{p}$ final state. In addition, the inclusive branching fraction of ${b}$ -hadron decays into $\eta _c (1S)$ mesons is measured, for the first time, to be ${\mathcal{B}}( b {\rightarrow } \eta _c X ) = (4.88\, \pm \,0.64\, \pm \,0.29\, \pm \, 0.67 _{{\mathcal{B}}}) \times 10^{-3}$ , where the third uncertainty includes also the uncertainty on the ${{ J}}/{\psi }$ inclusive branching fraction from ${b}$ -hadron decays. The difference between the ${{ J}}/{\psi }$ and $\eta _c (1S)$ meson masses is determined to be $114.7 \pm 1.5 \pm 0.1 {\mathrm {\,MeV\!/}c^2}$ .The production of the $\eta_c (1S)$ state in proton-proton collisions is probed via its decay to the $p \bar{p}$ final state with the LHCb detector, in the rapidity range $2.0 6.5$ GeV/c. The cross-section for prompt production of $\eta_c (1S)$ mesons relative to the prompt $J/\psi$ cross-section is measured, for the first time, to be $\sigma_{\eta_c (1S)}/\sigma_{J/\psi} = 1.74 \pm 0.29 \pm 0.28 \pm 0.18 _{B}$ at a centre-of-mass energy $\sqrt{s} = 7$ TeV using data corresponding to an integrated luminosity of 0.7 fb$^{-1}$, and $\sigma_{\eta_c (1S)}/\sigma_{J/\psi} = 1.60 \pm 0.29 \pm 0.25 \pm 0.17 _{B}$ at $\sqrt{s} = 8$ TeV using 2.0 fb$^{-1}$. The uncertainties quoted are, in order, statistical, systematic, and that on the ratio of branching fractions of the $\eta_c (1S)$ and $J/\psi$ decays to the $p \bar{p}$ final state. In addition, the inclusive branching fraction of $b$-hadron decays into $\eta_c (1S)$ mesons is measured, for the first time, to be $B ( b \rightarrow \eta_c X ) = (4.88 \pm 0.64 \pm 0.29 \pm 0.67 _{B}) \times 10^{-3}$, where the third uncertainty includes also the uncertainty on the $J/\psi$ inclusive branching fraction from $b$-hadron decays. The difference between the $J/\psi$ and $\eta_c (1S)$ meson masses is determined to be $114.7 \pm 1.5 \pm 0.1$ MeV/c$^2$

Search for the lepton flavour violating decay tau(-) -&gt; mu(-)mu(+)mu(-)

A search for the lepton flavour violating decay $\tau^-\rightarrow\mu^-\mu^+\mu^-$ is performed with the LHCb experiment. The data sample corresponds to an integrated luminosity of 1.0 fb$^{−1}$ of proton-proton collisions at a centre-of-mass energy of 7 TeV and 2.0 fb$^{−1}$ at 8 TeV. No evidence is found for a signal, and a limit is set at 90% confidence level on the branching fraction, $\mathcal{B}(\tau^-\rightarrow\mu^-\mu^+\mu^-)<4.6\times10^{−8}$.A search for the lepton flavour violating decay τ$^{−}$ → μ$^{−}$ μ$^{+}$ μ$^{−}$ is performed with the LHCb experiment. The data sample corresponds to an integrated luminosity of 1.0 fb$^{−1}$ of proton-proton collisions at a centre-of-mass energy of 7 TeV and 2.0 fb$^{−1}$ at 8 TeV. No evidence is found for a signal, and a limit is set at 90% confidence level on the branching fraction, $\mathrm{\mathcal{B}}\left({\tau}^{-}\to {\mu}^{-}{\mu}^{+}{\mu}^{-}\right)<4.6\times {10}^{-8}$ .A search for the lepton flavour violating decay $\tau^-\to \mu^-\mu^+\mu^-$ is performed with the LHCb experiment. The data sample corresponds to an integrated luminosity of $1.0\mathrm{\,fb}^{-1}$ of proton-proton collisions at a centre-of-mass energy of $7\mathrm{\,Te\kern -0.1em V}$ and $2.0\mathrm{\,fb}^{-1}$ at $8\mathrm{\,Te\kern -0.1em V}$. No evidence is found for a signal, and a limit is set at $90\%$ confidence level on the branching fraction, $\mathcal{B}(\tau^-\to \mu^-\mu^+\mu^-) < 4.6 \times 10^{-8}$

Observation of the B0 → ρ0ρ0 decay from an amplitude analysis of B0 → (π+π−)(π+π−) decays

Proton–proton collision data recorded in 2011 and 2012 by the LHCb experiment, corresponding to an integrated luminosity of 3.0 fb−1 , are analysed to search for the charmless B0→ρ0ρ0 decay. More than 600 B0→(π+π−)(π+π−) signal decays are selected and used to perform an amplitude analysis, under the assumption of no CP violation in the decay, from which the B0→ρ0ρ0 decay is observed for the first time with 7.1 standard deviations significance. The fraction of B0→ρ0ρ0 decays yielding a longitudinally polarised final state is measured to be fL=0.745−0.058+0.048(stat)±0.034(syst) . The B0→ρ0ρ0 branching fraction, using the B0→ϕK⁎(892)0 decay as reference, is also reported as B(B0→ρ0ρ0)=(0.94±0.17(stat)±0.09(syst)±0.06(BF))×10−6