183 research outputs found
The Ursinus Weekly, November 1, 1954
MSGA buys record player • Pre-medical society tours medical college • Mayberry completes course • Deltas present Greditzia Moraine to college • Stardust top song • The Monkey\u27s Paw Group I production • U.S. Naval Reserve to visit Ursinus on November 17 • Naval aviation cadet program here, Nov. 15 • Dr. Lionel Mapp to speak on Trinidad: Medical and ethnic • Rabbi Schorsch speaks on religion • Wood sweeps Ursinus election by 64% • High school groups see campus, slides • Unique features in Night of Jan. 16th • Earle elected president of U.C. Canterbury Club • Beardwood meeting tonight; Dr. A.G. Oblad to speak • Sororities change rushing schedule because of holiday • Rushee cooling off period • Does college life promote maturity? • Junior class to sponsor Harvest moon ball dance • Editorial: Sanctuary of silence? • Bears maul shaky Wagner eleven 34-7: Famous counters 2 Td\u27s; Walker sparks UC assault • UC whitewashed 1-0 at Swarthmorehttps://digitalcommons.ursinus.edu/weekly/1458/thumbnail.jp
The Ursinus Weekly, October 18, 1954
Hazel invades Y-retreat but festivities continue • Juniors next for pictures • Intramural debate to be held Friday • B.A. admission tests • Sorority rushing schedule set up by I-S Council • Guilty or not guilty answer to Jan. 16th • Old Timers\u27 Day big day for alumni and students • Carl Smith FTAVP • Pre-legal to hold meeting • Politics and humor mix at first Ursinus Forum • MSGA holds open meeting • Political situation in France topic at French Club meeting • New Weekly series to start • Students attend Chi Alpha meeting: Aregood presides • Fraternities view prospects • Lantern adds 13 members • Abstractly speaking • Cheers for the substitutes • Dinner opens Canterbury year • Belles blank Garnet by 3-0 • Curtis captures title by downing Brodbeck • Weekly sponsors music poll • Gridmen rebound to stall Haverford, 12-0 • Booters remain undefeated; Zartman, Dawkins, Burger star • Supply Store reveals policyhttps://digitalcommons.ursinus.edu/weekly/1456/thumbnail.jp
Nycteribiid bat flies (Arthropoda, Insecta, Diptera, Nycteribiidae) of Kenya
Bat flies (Diptera: Nycteribiidae and Streblidae) are hematophagous ectoparasites of bats characterized by viviparous pupiparity and generally high host specificity. Nycteribiid bat flies are wingless, morphologically constrained, and are most diverse in the Eastern Hemisphere. Africa hosts approximately 22% of global bat biodiversity and nearly one-third of all African bat species occur in Kenya, one of Africa’s most bat-rich countries. However, records of nycteribiid bat fly diversity in Kenya remain sparse and unconsolidated. This paper combines all past species records of nycteribiid bat flies with records from a survey of 4,255 Kenyan bats across 157 localities between 2006 and 2015. A total of seven nycteribiid genera and 17 species are recorded, with seven species from the recent ‘Bats of Kenya’ surveys representing previously undocumented country records. Host associations and geographic distributions based on all available records are also described. This comprehensive species catalog addresses and further emphasizes the need for similar investigations of nycteribiid biodiversity across Africa
The Ursinus Weekly, November 8, 1954
Dr. Lionel Mapp to speak at Ursinus forum Nov. 10 • WSGA announces party, election of representatives • Mr. T. Allen Glenn will speak at FTA meeting • Fraternity row • Seniors to elect Lord and Lady • KDK, Deltas plan clothing drive • Frosh elect class officers; Choose executive committee • Fantasy in fire theme of Friday night soph dance • WRC group plans trip to UN and Brooklyn College • Curtain Club cast seeks realism for annual Fall play • Jurors picked from audience for Night of January 16th • Newman Club members commune at St. Eleanor\u27s • Looking and listening • Know your college • Deep passion • Student Union badly needed • Were you caught too? • Unleashed Greyhounds gnaw Bruins: Moravian 47-6 victor as mud, injuries plague UC • Basketball squad drills nightly • Heller, Bauser named to first team all-college • Girls whitewash Rosemont 5-0; Lose close Temple game 3-2https://digitalcommons.ursinus.edu/weekly/1459/thumbnail.jp
The Ursinus Weekly, October 11, 1954
The Night of January 16th to be Curtain Club Fall play • Gayle Livingstone wins essay award • History Department starts Bible study group • Fraternity row • IRC invites students • Beemer, Ramsey get NR commission • WSGA classified Bermuda shorts • God, our help in ages past theme for weekend retreat • Chem. society opens term • Y \u27s plan for \u2754-\u2755 • FTA to hold first meeting • Forum on October 31st • Maples and Lynnewood have new preceptresses • Editorials • Cub and Key celebrate 15th anniversary • Debators campaign • Paolone sets \u2754-\u2755 MSGA in motion • P-T day • Band lays plans for Old Timers\u27 Day • Maintenance men active • French Club to meet Tues. • Continental observer • Price of originality • Volume XXII of The Lantern • Captain Stadler, hockey gals out to beat 1-loss 1953 mark • Ehlers\u27 passing nets Curtis lead in grid campaign • Don\u27t buy your spirit, we have it for free! • Conti, Carver break away to blank Crusaders, 12-0 • Fall volleyball replaces hockey in intramurals • Fumble, blocked kicks aid Drexel win: Dragons maul Bears 41-13; Hart, Campiglia big guns • Booters down Hill School in 5-1 opener; Four back • Stick gals bow to Beaver 5-3 after injury to Ruth Heller • Emerald gals use teamwork in 7-0 victory • Chess Club elects Scheirer new prexy • Aregood to preside over first Chi Alpha meeting • Frosh united? • Want an activity? Join the Y • Robert Sutton new librarianhttps://digitalcommons.ursinus.edu/weekly/1455/thumbnail.jp
A genome-wide association study of anorexia nervosa.
Anorexia nervosa (AN) is a complex and heritable eating disorder characterized by dangerously low body weight. Neither candidate gene studies nor an initial genome-wide association study (GWAS) have yielded significant and replicated results. We performed a GWAS in 2907 cases with AN from 14 countries (15 sites) and 14 860 ancestrally matched controls as part of the Genetic Consortium for AN (GCAN) and the Wellcome Trust Case Control Consortium 3 (WTCCC3). Individual association analyses were conducted in each stratum and meta-analyzed across all 15 discovery data sets. Seventy-six (72 independent) single nucleotide polymorphisms were taken forward for in silico (two data sets) or de novo (13 data sets) replication genotyping in 2677 independent AN cases and 8629 European ancestry controls along with 458 AN cases and 421 controls from Japan. The final global meta-analysis across discovery and replication data sets comprised 5551 AN cases and 21 080 controls. AN subtype analyses (1606 AN restricting; 1445 AN binge-purge) were performed. No findings reached genome-wide significance. Two intronic variants were suggestively associated: rs9839776 (P=3.01 × 10(-7)) in SOX2OT and rs17030795 (P=5.84 × 10(-6)) in PPP3CA. Two additional signals were specific to Europeans: rs1523921 (P=5.76 × 10(-)(6)) between CUL3 and FAM124B and rs1886797 (P=8.05 × 10(-)(6)) near SPATA13. Comparing discovery with replication results, 76% of the effects were in the same direction, an observation highly unlikely to be due to chance (P=4 × 10(-6)), strongly suggesting that true findings exist but our sample, the largest yet reported, was underpowered for their detection. The accrual of large genotyped AN case-control samples should be an immediate priority for the field
Large-scale analysis of structural brain asymmetries in schizophrenia via the ENIGMA consortium
Left-right asymmetry is an important organizing feature of the healthy brain that may be altered in schizophrenia, but most studies have used relatively small samples and heterogeneous approaches, resulting in equivocal findings. We carried out the largest case-control study of structural brain asymmetries in schizophrenia, using MRI data from 5,080 affected individuals and 6,015 controls across 46 datasets in the ENIGMA consortium, using a single image analysis protocol. Asymmetry indexes were calculated for global and regional cortical thickness, surface area, and subcortical volume measures. Differences of asymmetry were calculated between affected individuals and controls per dataset, and effect sizes were meta-analyzed across datasets. Small average case-control differences were observed for thickness asymmetries of the rostral anterior cingulate and the middle temporal gyrus, both driven by thinner left-hemispheric cortices in schizophrenia. Analyses of these asymmetries with respect to the use of antipsychotic medication and other clinical variables did not show any significant associations. Assessment of age- and sex-specific effects revealed a stronger average leftward asymmetry of pallidum volume between older cases and controls. Case-control differences in a multivariate context were assessed in a subset of the data (N = 2,029), which revealed that 7% of the variance across all structural asymmetries was explained by case-control status. Subtle case-control differences of brain macro-structural asymmetry may reflect differences at the molecular, cytoarchitectonic or circuit levels that have functional relevance for the disorder. Reduced left middle temporal cortical thickness is consistent with altered left-hemisphere language network organization in schizophrenia
Multiple novel prostate cancer susceptibility signals identified by fine-mapping of known risk loci among Europeans
Genome-wide association studies (GWAS) have identified numerous common prostate cancer (PrCa) susceptibility loci. We have
fine-mapped 64 GWAS regions known at the conclusion of the iCOGS study using large-scale genotyping and imputation in
25 723 PrCa cases and 26 274 controls of European ancestry. We detected evidence for multiple independent signals at 16
regions, 12 of which contained additional newly identified significant associations. A single signal comprising a spectrum of
correlated variation was observed at 39 regions; 35 of which are now described by a novel more significantly associated lead SNP,
while the originally reported variant remained as the lead SNP only in 4 regions. We also confirmed two association signals in
Europeans that had been previously reported only in East-Asian GWAS. Based on statistical evidence and linkage disequilibrium
(LD) structure, we have curated and narrowed down the list of the most likely candidate causal variants for each region.
Functional annotation using data from ENCODE filtered for PrCa cell lines and eQTL analysis demonstrated significant
enrichment for overlap with bio-features within this set. By incorporating the novel risk variants identified here alongside the
refined data for existing association signals, we estimate that these loci now explain ∼38.9% of the familial relative risk of PrCa,
an 8.9% improvement over the previously reported GWAS tag SNPs. This suggests that a significant fraction of the heritability of
PrCa may have been hidden during the discovery phase of GWAS, in particular due to the presence of multiple independent
signals within the same regio
Mammal collections of the Western Hemisphere: A survey and directory of collections
As a periodic assessment of the mammal collection resource, the Systematic Collections Committee (SCC) of the American Society of Mammalogists undertakes decadal surveys of the collections held in the Western Hemisphere. The SCC surveyed 429 collections and compiled a directory of 395 active collections containing 5,275,155 catalogued specimens. Over the past decade, 43 collections have been lost or transferred and 38 new or unsurveyed collections were added. Growth in number of total specimens, expansion of genomic resource collections, and substantial gains in digitization and web accessibility were documented, as well as slight shifts in proportional representation of taxonomic groups owing to increasingly balanced geographic representation of collections relative to previous surveys. While we find the overall health of Western Hemisphere collections to be adequate in some areas, gaps in spatial and temporal coverage and clear threats to long-term growth and vitality of these resources have also been identified. Major expansion of the collective mammal collection resource along with a recommitment to appropriate levels of funding will be required to meet the challenges ahead for mammalogists and other users, and to ensure samples are broad and varied enough that unanticipated future needs can be powerfully addressed. © 2018 The Author(s)
- …