Climatology and ranking of hazardous precipitation events in the western Mediterranean area

The western Mediterranean region often suffers from the devastating effects of flooding, caused by enormous rain accumulations that sometimes resemble the values produced by tropical systems. Despite the climatic and social relevancy of this type of episodes, there are some fundamental questions that would still be difficult to answer today, for example: where within the region are more cases recorded? or, which were the most potentially dangerous episodes? In this study, we identify, and then gather and unify information from, all the daily events occurred from 1980 to 2015. Using the MESCAN high-resolution gridded rainfall dataset, events are detected and for each case, the date and affected regions are recorded. Subsequently, events are ranked according to their magnitude and classified by weather type. In addition, flood data from the FLOODHYMEX and EM-DAT databases are used to check whether the precipitation episodes resulted in flooding. All this information is collected into a publicly available single database. Results show that the highest number of events per year is recorded in the Languedoc-Roussillon region (France) and in the Valencian Community (Spain). The cases of greatest magnitude, which are associated with a larger number of floods, present a very marked seasonality, with about 80% of them occurring in September, October and November. Finally, we show that only four weather types are present in most of the days with hazardous rainfall in the western Mediterranean. The most hazardous situation is characterized by a low-pressure area at all tropospheric levels in the eastern Atlantic, forming a block pattern with an anticyclonic ridge that tends to extend from the Central Mediterranean to Central Europe. About 40% of the most extraordinary cases are associated with this configuration. As an example, the infamous Piedmont (Italy) 1994 episode, in the top 10 of the ranking, was produced by an atmospheric pattern of this typeFunding comes from the Spanish Ministerio de Economia y Competitividad OPERMO (CGL2017-89859-R to GMM and DIC), CLICES (CGL2017-83866-C3-2-R to MLC) and M-CostAdapt (CTM2017-83655-C2-2-R to MCLL) projects, the European Union Interreg V POCTEFA project (EFA210/16 PIRAGUA to MCLL) and the CRETUS strategic partnership (AGRUP2015/02 to GMM and DIC). All these programs are co-funded by the European Union ERDF. DIC and MLC were awarded a pre-doctoral FPI (PRE2018-084425) and FPU (FPU2017/02166) grant, respectively, both from the Spanish Ministry of Science, Innovation and UniversitiesS

Visions of the World by Pepper and its application to Health Education

INTRODUCCIÓN: Las metáforas impregnan nuestra vida cotidiana y no sólo el lenguaje también el pensamiento y la acción. La enfermera usa las metáforas como recurso didáctico para facilitar la comunicación y la comprensión de conceptos abstractos. Los usuarios expresan sus vivencias de salud o enfermedad a través de metáforas de su ámbito personal y cotidiano. La comprensión del uso de las metáforas en Educación para la Salud (EpS) requiere examinar también los paradigmas dentro de los cuales las metáforas son construidas. Este estudio pretende conocer las metáforas básicas o “visones del mundo” que utilizan la enfermera en la consulta de atención primaria en sus intervenciones educativas-asistenciales con usuarios afectados enfermedades crónicas

Aproximaciones metabolómica y transcriptómica a la gestión del metabolismo en las acículas de Pinus pinaster L. aiton

Aproximaciones metabolómica y transcriptómica a la gestión del metabolismo en las acículas de Pinus pinaster L. Aiton Rafael A. Cañas1, Javier Canales1, Carmen Muñoz2, Jose M. Granados1, Ma Belén Pascual1, Concepción Ávila1, María L. García-Martín2, Francisco M. Cánovas1. 1Departamento de Biología Molecular y Bioquímica, Facultad de Ciencias, Instituto Andaluz de Biotecnología, Universidad de Málaga, Campus Universitario de Teatinos s/n, 29071, MÁLAGA. [email protected] 2Unidad de Nanoimagen, Centro Andaluz de Nanomedicina y Biotecnología (BIONAND), Parque Tecnológico de Andalucía, C/ Severo Ochoa 35, 29590 Campanillas (MÁLAGA) El pino marítimo (Pinus pinaster L. Aiton) es una conífera de hoja perenne con un ciclo de vida largo y cuyas acículas pueden permanecer activas en el árbol varios años. Las coníferas y, en concreto, P. pinaster son especies modelo en el contexto de la producción de madera o de la síntesis de los flavonoides y terpenoides, componentes de la resina. A pesar de ello, el metabolismo y la biología molecular de las hojas (acículas) de las coníferas han sido escasamente estudiados por lo que las relaciones entre los tejidos productores o fuentes y los tejidos consumidores o sumideros no son bien conocidas en este grupo de plantas. En este trabajo nos proponemos el estudio de las acículas desde dos aproximaciones distintas: la metabolómica y la transcriptómica. Para ello se han obtenido muestras de acículas de P. pinaster en condiciones naturales a lo largo de un año completo separando las acículas por su edad. El estudio metabolómico se ha desarrollado mediante H1-NMR para lo que se ha desarrollado una librería de espectros de referencia de 70 metabolitos diferentes. Para el estudio transcriptómico se ha empleado un microarray de cDNA con 8.000 puntos de hibridación (PINARRAY2) y que ha sido desarrollado por nuestro grupo de investigación. Para el estudio de los datos obtenidos se ha empleado un análisis de redes de co-expresión (WGCNA).Universidad de Málaga. Campus de Excelencia Internacional Andalucía Tech

DISPERSE, a trait database to assess the dispersal potential of European aquatic macroinvertebrates

Dispersal is an essential process in population and community dynamics, but is difficult to measure in the field. In freshwater ecosystems, information on biological traits related to organisms’ morphology, life history and behaviour provides useful dispersal proxies, but information remains scattered or unpublished for many taxa. We compiled information on multiple dispersal-related biological traits of European aquatic macroinvertebrates in a unique resource, the DISPERSE database. DISPERSE includes nine dispersal-related traits subdivided into 39 trait categories for 480 taxa, including Annelida, Mollusca, Platyhelminthes, and Arthropoda such as Crustacea and Insecta, generally at the genus level. Information within DISPERSE can be used to address fundamental research questions in metapopulation ecology, metacommunity ecology, macroecology and evolutionary ecology. Information on dispersal proxies can be applied to improve predictions of ecological responses to global change, and to inform improvements to biomonitoring, conservation and management strategies. The diverse sources used in DISPERSE complement existing trait databases by providing new information on dispersal traits, most of which would not otherwise be accessible to the scientific community. Measurement(s): dispersal • movement quality • morphological feature • behavioral quality Technology Type(s): digital curation Factor Type(s): taxon Sample Characteristic - Organism: Arthropoda • Mollusca • Annelida Sample Characteristic - Environment: aquatic biome • freshwater biome Sample Characteristic - Location: Europe Machine-accessible metadata file describing the reported data: https://doi.org/10.6084/m9.figshare.1314833

Pla funcional del Programa d’incorporació de fisioterapeutes a l’atenció primària i comunitària: programa d’incorporació de fisioterapeutes per a la promoció del funcionament i la prevenció de la discapacitat a l’atenció primària i comunitària

Fisioterapeutes; Atenció primària; IncorporacióFisioterapeutas; Atención primaria; IncorporaciónPhysiotherapists; Primary care; IncorporationEl present pla funcional és una eina de suport per a l’acollida i la incorporació dels nous fisioterapeutes1 d’atenció primària i comunitària (FisioAPiC) als equips d’atenció primària (EAP) d’arreu de Catalunya. Aquest és un document dinàmic que requerirà les aportacions dels professionals dels EAP que han incorporat aquest nou rol per tal de fer-lo evolucionar i enriquir-lo en les versions següents

From corneal shape to ocular wavefront in eyes with aspheric IOLs:the feasibility of IOL customisation

Purpose: To determine if it is possible to predict the ocular wavefront aberrations of eyes with an aspheric IOL from the corneal shape and other readily available eye characteristics. A reliable prediction is a prerequisite for future IOL customisation. Methods: Sixty pseudophakic eyes with aspheric IOLs of 60 patients were included. The corneal shape and the ocular wavefront aberrations were measured postoperatively with a Scheimpflug camera and an aberrometer, respectively. The elevation data of the anterior corneal surface were fitted by Zernike polynomials. Linear regression models for the Zernike coefficients describing the ocular wavefront aberrations up till the fourth order were determined, with as independent variables the Zernike coefficients describing the corneal shape, the eye (right/left), IOL power, and axial length. Results: Linear regression equations with an explained variance (adjusted R-square) above 0.50 were found for five Zernike aberration terms: defocus (z (2,0); adjusted R-square 0.90), the astigmatism terms (0.81 for oblique astigmatism [z(2,-2)] and 0.88 for regular astigmatism [z(2,2)]), vertical coma (z(3,-1); 0.52), and spherical aberration (z(4,0); 0.71). Conclusion: The defocus, astigmatism, vertical coma, and spherical aberration terms of the ocular wavefront are strongly associated with the corneal shape in pseudophakic eyes and may thus be predicted from the corneal shape and other eye characteristics

A sustainable amperometric biosensor for the analysis of ascorbic, benzoic, gallic and kojic acids through catechol detection. Innovation and signal processing

In this work, we present a new catechol amperometric biosensor fabricated on the basis of naturally available enzymes in common mushrooms. The biosensor response mechanism comprises the reduction of the quinone exclusively produced in the oxidation of the catechol present in the sample, which is catalyzed by tyrosinase enzyme. The new catechol biosensor has demonstrated excellent analytical performance at increasing catechol concentrations in the sample solution, which includes superior reproducibility for several electrodes and long-term stability. On top of that, the biosensing element used in the fabrication is a sustainable material, of low-cost and presents an excellent lifetime of years. Whether the catechol biosensor is operating in the presence of a compound influencing the reactions underlying the amperometric response (such as ascorbic, benzoic, gallic and kojic acids), this serves as an analytical platform to detect these compounds in real samples. Particularly, we introduce herein for the first time different treatments to process the current signal of the biosensor pursuing the linearity needed for the analytical application in real samples. In this sense, the catechol biosensor has been successfully applied to the detection of benzoic, gallic and kojic acids in juices, teas and cosmetic products, respectively.QC 20211129</p

Discrimination between Alternative Substrates and Inhibitors of Tyrosinase

Many phenolic compounds have been described in the scientific literature as inhibitors of tyrosinase. In this work a test is proposed that allows us to distinguish whether a molecule is an enzyme inhibitor or substrate. The test has several stages. First, the degree of inhibition of the studied molecule is determined on the monophenolase activity (<i>i</i>_M) and on the diphenolase activity (<i>i</i>_D). If <i>i</i>_M = <i>i</i>_D, it is an inhibitor. If <i>i</i>_M ≠ <i>i</i>_D, the molecule could be substrate or inhibitor. Several additional stages are proposed to solve this ambiguity. The study described herein was carried out using the following molecules: benzoic acid, cinnamic acid, guaiacol, isoeugenol, carvacrol, 4-<i>tert</i>-butylphenol, eugenol, and arbutin