267 research outputs found

    Descripcions i notícies del gabinet Salvador en llibres de viatges, guies i altres documents impresos (1713-1895)

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    Between the beginning of the 18th century and the mid-19th century the Salvador cabinet was a must for all those interested in natural history or simply curious people or scholars who passed through the city of Barcelona. Not all of these visitors have left written testimony of its passage by the cabinet, nor even less printed testimony, but the half a hundred of notices, descriptions or opinions that we have been able to locate cover virtually the whole of this period (even exceed it) and constitute a valuable witness to the transformations of the cabinet along time and of the evolution in the appraisal of the cabinet and its contents by the successive visitors. An Appendix includes texts and bibliographic references of this notices, descriptions or opinions about the Salvador cabinet.Entre comienzos del siglo XVIII y mediados del siglo XIX el gabinete de los Salvador era de visita obligada para cuantos interesados por la historia natural o simplemente curiosos o eruditos que pasaban por la ciudad de Barcelona. No todos aquellos visitantes han dejado testimonio escrito de su paso por el gabinete, ni menos aún testimonio publicado, pero el medio centenar de noticias, descripciones o juicios que hemos podido localizar cubren prácticamente la totalidad de este período (incluso lo superan) y constituyen un valioso testimonio de las transformaciones del gabinete y de la evolución en la valoración de éste y de su contenido por parte de los sucesivos visitantes. En el apéndice se incluyen los textos y las referencias de estas noticias, descripciones y juicios acerca del gabinete Salvador. [ca] Entre començaments del segle XVIII i mitjan segle XIX el gabinet dels Salvador va ser de visita obligada per a tots els interessats per la història natural o simplement curiosos o erudits que passaven per la ciutat de Barcelona. No tots aquells visitants han deixat testimoni escrit del seu pas pel gabinet ni encara menys testimoni imprès però el mig centenar de notícies, descripcions o judicis que hem pogut localitzar cobreixen pràcticament la totalitat d’aquest període (fins i tot l’ultrapassen) i constitueixen un valuós testimoni de les transformacions del gabinet i de l’evolució en la valoració del gabinet mateix i del seu contingut per part dels successius visitants. En l’apèndix s’inclouen els textos i les referències d’aquestes notícies, descripcions i judicis sobre el gabinet Salvador

    Mapping temporally-variable exposure to flooding in small Mediterranean basins using land-use indicators

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    This article deals with mapping exposure (or external vulnerability) to flood risk in two typical Mediterranean ephemeral streams: the Barranco de Carraixet and the Rambla de Poyo. The floodplains of both streams are within the metropolitan area of the city of Valencia (Spain"s third largest city). Following the Mediterranean model, they are very fertile areas (with intense periurban and highly productive agriculture) which have recently absorbed the great urban expansion of the metropolis. Hydrologically these basins remain dry for most of the year, but become particularly dangerous during flash-flood events. They generate a risk pattern highly dependent on exposure since, in general, the hazard factor is very difficult to map, given the unpredictable nature of flash-floods. This work constitutes a proof of concept based on simple estimators obtained from land uses. External vulnerability or exposure is evaluated as a function of economic land value and human exposure to hazard. Land value is directly taken from the cadastre whilst human exposure is indirectly estimated from the location of population in relation to timeeactivity profiles. The temporal dimension is introduced and three exposure scenarios have been mapped, related to different time periods: working days, nights, weekends and holidays. The results show different patterns of exposure for each plain. In Carraixet floodplain exposure is greater at night and on weekends and holidays than during working hours, on account of the dominant agricultural and residential land uses. In the Poyo plain there are no major contrasts in absolute terms between day and night time, although spatial patterns of exposure vary from day to night: during the day, exposure is higher in industrial and commercial areas (around communication routes) whilst at night residential areas show more exposure

    1,3,5-Triazines with aromatic amino acids: Exploring their potential as lectin mimetics

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    VII Escuela de verano de la SEQT, Sociedad Española de Química Terapeútica, Barcelona, 19-21 Julio, 202

    La acústica submarina y su desarrollo desde la creación del Instituto de Acústica

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    PACS: 43.30.Xm; 43.30.Yj; 43.30.Vh; 43.30.Nb; 43.30.Ma.-- Publicado en el Vol. XXXI, núm. 3-4, tercer y cuarto trimestre 2000 de la Revista de Acústica: Número especial dedicado al XXV Aniversario del Instituto de Acústica del C.S.I.C.[ES] La Acústica Submarina fue una de las líneas de la Acústica que se desarrollan en el Instituto desde los primeros tiempos. Este trabajo describe como se inició, cómo se desarrolló y el estado actual de este campo.[EN] Underwater Acoustics was one line of Acoustics first developped at the Instituto de Acústica. This paper presents a description of the activities in the underwater field, done since 1969, when the Underwater Tank was installed, up to the present times.Peer reviewe

    Organic synthesis in a modular robotic system driven by a chemical programming language

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    The synthesis of complex organic compounds is largely a manual process that is often incompletely documented. To address these shortcomings, we developed an abstraction that maps commonly reported methodological instructions into discrete steps amenable to automation. These unit operations were implemented in a modular robotic platform using a chemical programming language which formalizes and controls the assembly of the molecules. We validated the concept by directing the automated system to synthesize three pharmaceutical compounds, Nytol, rufinamide, and sildenafil, without any human intervention. Yields and purities of products and intermediates were comparable to or better than those achieved manually. The syntheses are captured as digital code that can be published, versioned, and transferred flexibly between platforms with no modification, thereby greatly enhancing reproducibility and reliable access to complex molecules

    A multi-component flood risk assessment in the Maresme coast (NW Mediterranean)

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    Coastal regions are the areas most threatened by natural hazards, with floods being the most frequent and significant threat in terms of their induced impacts, and therefore, any management scheme requires their evaluation. In coastal areas, flooding is a hazard associated with various processes acting at different scales: coastal storms, flash floods, and sea level rise (SLR). In order to address the problem as a whole, this study presents a methodology to undertake a preliminary integrated risk assessment that determines the magnitude of the different flood processes (flash flood, marine storm, SLR) and their associated consequences, taking into account their temporal and spatial scales. The risk is quantified using specific indicators to assess the magnitude of the hazard (for each component) and the consequences in a common scale. This allows for a robust comparison of the spatial risk distribution along the coast in order to identify both the areas at greatest risk and the risk components that have the greatest impact. This methodology is applied on the Maresme coast (NW Mediterranean, Spain), which can be considered representative of developed areas of the Spanish Mediterranean coast. The results obtained characterise this coastline as an area of relatively low overall risk, although some hot spots have been identified with high-risk values, with flash flooding being the principal risk process

    Multivalent Tryptophan- and Tyrosine-Containing [60]Fullerene Hexa-Adducts as Dual HIV and Enterovirus A71 Entry Inhibitors

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    Unprecedented 3D hexa-adducts of [60]fullerene peripherally decorated with twelve tryptophan (Trp) or tyrosine (Tyr) residues have been synthesized. Studies on the antiviral activity of these novel compounds against HIV and EV71 reveal that they are much more potent against HIV and equally active against EV71 than the previously described dendrimer prototypes AL-385 and AL-463, which possess the same number of Trp/Tyr residues on the periphery but attached to a smaller and more flexible pentaerythritol core. These results demonstrate the relevance of the globular 3D presentation of the peripheral groups (Trp/Tyr) as well as the length of the spacer connecting them to the central core to interact with the viral envelopes, particularly in the case of HIV, and support the hypothesis that [60]fullerene can be an alternative and attractive biocompatible carbon-based scaffold for this type of highly symmetrical dendrimers. In addition, the functionalized fullerenes here described, which display twelve peripheral negatively charged indole moieties on their globular surface, define a new and versatile class of compounds with a promising potential in biomedical applications.status: publishe
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