201 research outputs found
Recent Advances Concerning Certain Class of Geophysical Flows
This paper is devoted to reviewing several recent developments concerning
certain class of geophysical models, including the primitive equations (PEs) of
atmospheric and oceanic dynamics and a tropical atmosphere model. The PEs for
large-scale oceanic and atmospheric dynamics are derived from the Navier-Stokes
equations coupled to the heat convection by adopting the Boussinesq and
hydrostatic approximations, while the tropical atmosphere model considered here
is a nonlinear interaction system between the barotropic mode and the first
baroclinic mode of the tropical atmosphere with moisture.
We are mainly concerned with the global well-posedness of strong solutions to
these systems, with full or partial viscosity, as well as certain singular
perturbation small parameter limits related to these systems, including the
small aspect ratio limit from the Navier-Stokes equations to the PEs, and a
small relaxation-parameter in the tropical atmosphere model. These limits
provide a rigorous justification to the hydrostatic balance in the PEs, and to
the relaxation limit of the tropical atmosphere model, respectively. Some
conditional uniqueness of weak solutions, and the global well-posedness of weak
solutions with certain class of discontinuous initial data, to the PEs are also
presented.Comment: arXiv admin note: text overlap with arXiv:1507.0523
Delayed baroclinic response of the Antarctic circumpolar current to surface wind stress
Author Posting. © Science in China Press, 2008. This is the author's version of the work. It is posted here by permission of Springer for personal use, not for redistribution. The definitive version was published in Science in China Series D: Earth Sciences 51 (2008): 1036-1043, doi:10.1007/s11430-008-0074-8.Antarctic Circumpolar Current (ACC) responds to the surface windstress via two processes, i.e., instant barotropic process and delayed baroclinic process. This study focuses on the baroclinic instability mechanism in ACC. That is, the strengthening of surface zonal windstress causes the enhanced tilting of the isopycnal surface, which leads to the intense baroclinic instability. Simultaneously, the mesoscale eddies resulting from the baroclinic instability facilitate the transformation of mean potential energy to eddy energy, which causes the remarkable decrease of the ACC volume transport with the 2-year lag time. This delayed negative correlation between the ACC transport and the zonal windstress may account for the steadiness of the ACC transport in these two decades.Supported by NSCF Outstanding Young Scientist Award (Grant No. 40625017) and the National Basic Research Program of China (Grant No. 2006CB403604). The research was also supported by W. Alan Clark Chair from Woods Hole Oceanographic Institution for RXH and NOAA GLERL contribution No. 1462 for J
Rotating Shallow Water Dynamics: Extra Invariant and the Formation of Zonal Jets
We show that rotating shallow water dynamics possesses an approximate
(adiabatic-type) positive quadratic invariant, which exists not only at
mid-latitudes (where its analogue in the quasigeostrophic equation has been
previously investigated), but near the equator as well (where the
quasigeostrophic equation is inapplicable). Deriving the extra invariant, we
find "small denominators" of two kinds: (1) due to the triad resonances (as in
the case of the quasigeostrophic equation) and (2) due to the equatorial limit,
when the Rossby radius of deformation becomes infinite. We show that the "small
denominators" of both kinds can be canceled. The presence of the extra
invariant can lead to the generation of zonal jets. We find that this tendency
should be especially pronounced near the equator. Similar invariant occurs in
magnetically confined fusion plasmas and can lead to the emergence of zonal
flows.Comment: 29 pages, 4 figure
Assembly of Protein Building Blocks Using a Short Synthetic Peptide
Combining proteins or their defined domains offers new enhanced functions. Conventionally, two proteins are either fused into a single polypeptide chain by recombinant means or chemically cross-linked. However, these strategies can have drawbacks such as poor expression (recombinant fusions) or aggregation and inactivation (chemical cross-linking), especially in the case of large multifunctional proteins. We developed a new linking method which allows site-oriented, noncovalent, yet irreversible stapling of modified proteins at neutral pH and ambient temperature. This method is based on two distinct polypeptide linkers which self-assemble in the presence of a specific peptide staple allowing on-demand and irreversible combination of protein domains. Here we show that linkers can either be expressed or be chemically conjugated to proteins of interest, depending on the source of the proteins. We also show that the peptide staple can be shortened to 24 amino acids still permitting an irreversible combination of functional proteins. The versatility of this modular technique is demonstrated by stapling a variety of proteins either in solution or to surfaces
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Increased light, moderate, and severe clear-air turbulence in response to climate change
Anthropogenic climate change is expected to strengthen the vertical wind shears at aircraft cruising altitudes
within the atmospheric jet streams. Such a strengthening would increase the prevalence of shear instabilities, which generate clear-air turbulence. Climate modelling studies have indicated that the amount of moderate-or-greater clear-air turbulence on transatlantic flight routes in winter will increase significantly in future as the climate changes. However, the individual responses of light, moderate, and severe clear-air turbulence have not previously been studied, despite their importance for aircraft operations.
Here we use climate model simulations to analyse the transatlantic wintertime clear-air turbulence response
to climate change in five aviation-relevant turbulence strength categories. We find that the probability distributions for an ensemble of 21 clear-air turbulence diagnostics generally gain probability in their right-hand tails when the atmospheric carbon dioxide concentration is doubled. By converting the diagnostics into equivalent eddy dissipation rates, we find that the ensemble-average airspace volume containing light clear-air turbulence increases by 59% (with an intra-ensemble range of 43–68%), light-to-moderate by 75% (39–96%), moderate by 94% (37–118%), moderate-to-severe by 127% (30–170%), and severe by 149% (36–188%). These results suggest that the prevalence of transatlantic wintertime clear-air turbulence will increase significantly in all aviation-relevant strength categories as the climate changes
A brief early intervention for adolescent depression that targets emotional mental images and memories: protocol for a feasibility randomised controlled trial (IMAGINE trial)
This is the final version of the article. Available from BioMed Central via the DOI in this record.Background: Adolescent depression is common and impairing. There is an urgent need to develop early interventions to prevent depression becoming entrenched. However, current psychological interventions are difficult to access and show limited evidence of effectiveness. Schools offer a promising setting to enhance access to interventions, including reducing common barriers such as time away from education. Distressing negative mental images and a deficit in positive future images, alongside overgeneral autobiographical memories, have been implicated in depression across the lifespan, and interventions targeting them in adults have shown promise. Here, we combine techniques targeting these cognitive processes into a novel, brief psychological intervention for adolescent depression. This feasibility randomised controlled trial will test the feasibility and acceptability of delivering this imagery-based cognitive behavioural intervention in schools. Methods/design: Fifty-six adolescents (aged 16-18) with high symptoms of depression will be recruited from schools. Participants will be randomly allocated to the imagery-based cognitive behavioural intervention (ICBI) or the control intervention, non-directive supportive therapy (NDST). Data on feasibility and acceptability will be recorded throughout, including data on recruitment, retention and adherence rates as well as adverse events. In addition, symptom assessment will take place pre-intervention, post-intervention and at 3-month follow-up. Primarily, the trial aims to establish whether it is feasible and acceptable to carry out this project in a school setting. Secondary objectives include collecting data on clinical measures, including depression and anxiety, and measures of the mechanisms proposed to be targeted by the intervention. The acceptability of using technology in assessment and treatment will also be evaluated. Discussion: Feasibility, acceptability and symptom data for this brief intervention will inform whether an efficacy randomised controlled trial is warranted and aid planning of this trial. If this intervention is shown in a subsequent definitive trial to be safe, clinically effective and cost-effective, it has potential to be rolled out as an intervention and so would significantly extend the range of therapies available for adolescent depression. This psychological intervention draws on cognitive mechanism research suggesting a powerful relationship between emotion and memory and uses imagery as a cognitive target in an attempt to improve interventions for adolescent depression. Trial registration: ISRCTN85369879.This study represents independent research from a Clinical Doctoral Research Fellowship (Dr Victoria Pile, ICA-CDRF-2015-01-007) supported by the National Institute for Health Research and Health Education England
Para-aortic irradiation for stage I testicular seminoma: results of a prospective study in 675 patients. A trial of the German testicular cancer study group (GTCSG)
Online prediction of others’ actions: the contribution of the target object, action context and movement kinematics
Previous research investigated the contributions of target objects, situational context and movement kinematics to action prediction separately. The current study addresses how these three factors combine in the prediction of observed actions. Participants observed an actor whose movements were constrained by the situational context or not, and object-directed or not. After several steps, participants had to indicate how the action would continue. Experiment 1 shows that predictions were most accurate when the action was constrained and object-directed. Experiments 2A and 2B investigated whether these predictions relied more on the presence of a target object or cues in the actor’s movement kinematics. The target object was artificially moved to another location or occluded. Results suggest a crucial role for kinematics. In sum, observers predict actions based on target objects and situational constraints, and they exploit subtle movement cues of the observed actor rather than the direct visual information about target objects and context
Stratosphere‐troposphere coupling and annular mode variability in chemistry‐climate models
The internal variability and coupling between the stratosphere and troposphere in CCMVal‐2 chemistry‐climate models are evaluated through analysis of the annular mode patterns of variability. Computation of the annular modes in long data sets with secular trends requires refinement of the standard definition of the annular mode, and a more robust procedure that allows for slowly varying trends is established and verified. The spatial and temporal structure of the models’ annular modes is then compared with that of reanalyses. As a whole, the models capture the key features of observed intraseasonal variability, including the sharp vertical gradients in structure between stratosphere and troposphere, the asymmetries in the seasonal cycle between the Northern and Southern hemispheres, and the coupling between the polar stratospheric vortices and tropospheric midlatitude jets. It is also found that the annular mode variability changes little in time throughout simulations of the 21st century. There are, however, both common biases and significant differences in performance in the models. In the troposphere, the annular mode in models is generally too persistent, particularly in the Southern Hemisphere summer, a bias similar to that found in CMIP3 coupled climate models. In the stratosphere, the periods of peak variance and coupling with the troposphere are delayed by about a month in both hemispheres. The relationship between increased variability of the stratosphere and increased persistence in the troposphere suggests that some tropospheric biases may be related to stratospheric biases and that a well‐simulated stratosphere can improve simulation of tropospheric intraseasonal variability
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