366 research outputs found

    Micro language planning for multilingual education : agency in local contexts

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    This paper overviews some of the domains of application of micro-level language planning approaches to foster multilingual education. It examines the language planning of local agents and the contexts in which their work contributes to multilingual education, either to expand or limit educational possibilities. It identifies four broad contexts of language planning activity in which local agents work: the local implementation of macro-level policy, contestation of macro-level policy, addressing local needs in the absence of macro-level policy and opening new possibilities for developing multilingualism. These contexts provide a way of framing the contribution that micro language planning work and local agents can make to multilingual education

    Controllo climatico sull'accumulo di sedimenti di margine Olocenici e Pleistocenici del Mar Tirreno Orientale

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    Dati di paleovariazioni secolari (PSV) del campo geomagnetico sono stati ottenuti negli ultimi 25.000 anni da diverse carote recuperate nel Golfo di Salerno (Mar Tirreno orientale). Le curve composte di PSV, sono comparate con le “ PSV Master Curves” britanniche e francesi. La comparazione fornisce uno strumento cronologico per determinare un trend di accrescimento del tasso di sedimentazione nell’ Olocene superiore e di variazione ad intervalli di circa 1000 anni nell’ Olocene medio della piattaforma. Inoltre durante i due principali episodi caldi del Mediterraneo a circa 3.3 e tra 6-9 ka sia la piattaforma che la scarpata superiore registrano un aumento con successiva diminuzione del tasso di sedimentazione, mentre ulteriori diminuzioni si registrano, in scarpata superiore, durante l’ ultimo picco Glaciale (LGM) e l’interstadio Bþlling-Allerþd, suggerendo cosi un’ influenza climatica sui processi di accumulo dei sedimenti del margine del Golfo di Salerno

    Vertical stratification in urban green space aerobiomes

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    Background: Exposure to a diverse environmental microbiome is thought to play an important role in “educating” the immune system and facilitating competitive exclusion of pathogens to maintain human health. Vegetation and soil are key sources of airborne microbiota––the aerobiome. A limited number of studies have attempted to characterize the dynamics of near surface green space aerobiomes, and no studies to date have investigated these dynamics from a vertical perspective. Vertical stratification in the aerobiome could have important implications for public health and for the design, engineering, and management of urban green spaces. Objectives: The primary objectives of this study were to: a) assess whether significant vertical stratification in bacterial species richness and evenness (alpha diversity) of the aerobiome occurred in a parkland habitat in Adelaide, South Australia; b) assess whether significant compositional differences (beta diversity) between sampling heights occurred; and c) to preliminarily assess whether there were significant altitudinal differences in potentially pathogenic and beneficial bacterial taxa. Methods: We combined an innovative columnar sampling method at soil level, 0.0, 0.5, 1.0, and 2.0m, using passive petri dish sampling to collect airborne bacteria. We used a geographic information system (GIS) to select study sites, and we used high-throughput sequencing of the bacterial 16S rRNA gene to assess whether significant vertical stratification of the aerobiome occurred. Results: Our results provide evidence of vertical stratification in both alpha and beta (compositional) diversity of airborne bacterial communities, with diversity decreasing roughly with height. We also found significant vertical stratification in potentially pathogenic and beneficial bacterial taxa. Discussion: Although additional research is needed, our preliminary findings point to potentially different exposure attributes that may be contingent on human height and activity type. Our results lay the foundations for further research into the vertical characteristics of urban green space aerobiomes and their implications for public health and urban planning

    Landscape biodiversity correlates with respiratory health in Australia

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    Megatrends of urbanisation and reducing contact with natural environments may pose a largely unappreciated risk to human health, particularly in children, through declining normal (healthy) immunomodulatory environmental exposures. On the other hand, building knowledge of connections between environments, biodiversity and human health may offer new integrated ways of addressing global challenges of rising population health costs and declining biodiversity. In this study we are motivated to build insight and provide context and priority for emerging research into potential protective (e.g. immunomodulatory) environmental exposures. We use respiratory health as a test case to explore whether some types and qualities of environment may be more beneficial than others, and how such exposures may compare to known respiratory health influences, via a cross-sectional ecological epidemiology study for the continent of Australia. Using Lasso penalized regression (to interpret key predictors from many candidate variables) and 10-fold cross-validation modelling (to indicate reproducibility and uncertainty), within different socio-geographic settings, our results show surrogate measures of landscape biodiversity correlate with respiratory health, and rank amongst known predictors. A range of possible drivers for this relationship are discussed. Perhaps most novel and interesting of these is the possibility of protective immunomodulatory influence from microbial diversity (suggested by the understudied ‘biodiversity hypothesis’) and other bioactive agents associated with biodiverse environments. If beneficial influences can be demonstrated from biodiverse environments on immunomodulation and human health, there may be potential to design new cost-effective nature-based health intervention programs to reduce the risk of immune-related disease at a population level. Our approach and findings are also likely to have use in the evaluation of environment and health associations elsewhere.Craig Liddicoat, Peng Bi, Michelle Waycott, John Glover, Andrew J. Lowe, Philip Weinstei

    Compatible fossil fuel CO2 emissions in the CMIP6 earth system models' historical and shared socioeconomic pathway experiments of the twenty-first century

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    We present the compatible CO2 emissions from fossil fuel (FF) burning and industry, calculated from the historical and Shared Socioeconomic Pathway (SSP) experiments of nine Earth system models (ESMs) participating in phase 6 of the Coupled Model Intercomparison Project (CMIP6). The multimodel mean FF emissions match the historical record well and are close to the data-based estimate of cumulative emissions (394 6 59 GtC vs 400 6 20 GtC, respectively). Only two models fall inside the observed uncertainty range; while two exceed the upper bound, five fall slightly below the lower bound, due primarily to the plateau in CO2 concentration in the 1940s. The ESMs' diagnosed FF emission rates are consistent with those generated by the integrated assessment models (IAMs) from which the SSPs' CO2 concentration pathways were constructed; the simpler IAMs' emissions lie within the ESMs' spread for seven of the eight SSP experiments, the other being only marginally lower, providing confidence in the relationship between the IAMs' FF emission rates and concentration pathways. The ESMs require fossil fuel emissions to reduce to zero and subsequently become negative in SSP1-1.9, SSP1-2.6, SSP4-3.4, and SSP5-3.4over. We also present the ocean and land carbon cycle responses of the ESMs in the historical and SSP scenarios. The models' ocean carbon cycle responses are in close agreement, but there is considerable spread in their land carbon cycle responses. Land-use and land-cover change emissions have a strong influence over the magnitude of diagnosed fossil fuel emissions, with the suggestion of an inverse relationship between the two. © 2021 American Meteorological Society. For information regarding reuse of this content and general copyright information, consult the AMS Copyright Policy (www.ametsoc.org/PUBSReuseLicenses)

    Twenty-first-century compatible co2 emissions and airborne fraction simulated by cmip5 earth system models under four representative concentration pathways

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    PublishedJournal ArticleThe carbon cycle is a crucial Earth system component affecting climate and atmospheric composition. The response of natural carbon uptake to CO2 and climate change will determine anthropogenic emissions compatible with a target CO2 pathway. For phase 5 of the Coupled Model Intercomparison Project (CMIP5), four future representative concentration pathways (RCPs) have been generated by integrated assessment models (IAMs) and used as scenarios by state-of-the-art climate models, enabling quantification of compatible carbon emissions for the four scenarios by complex, process-based models. Here, the authors present results from 15 such Earth system GCMs for future changes in land and ocean carbon storage and the implications for anthropogenic emissions. The results are consistent with the underlying scenarios but show substantial model spread. Uncertainty in land carbon uptake due to differences among models is comparable with the spread across scenarios. Model estimates of historical fossil-fuel emissions agree well with reconstructions, and future projections for representative concentration pathway 2.6 (RCP2.6) and RCP4.5 are consistent with the IAMs. For high-end scenarios (RCP6.0 and RCP8.5), GCMs simulate smaller compatible emissions than the IAMs, indicating a larger climate-carbon cycle feedback in the GCMs in these scenarios. For the RCP2.6 mitigation scenario, an average reduction of 50% in emissions by 2050 from 1990 levels is required but with very large model spread (14%-96%). The models also disagree on both the requirement for sustained negative emissions to achieve the RCP2.6 CO2 concentration and the success of this scenario to restrict global warming below 28C. All models agree that the future airborne fraction depends strongly on the emissions profile with higher airborne fraction for higher emissions scenarios. ©2013 American Meteorological Society.MOHC authors were supported by the JointDECC/Defra MetOffice Hadley Centre Climate Programme (GA01101), and work to performHadGEM2- ES and MPI-ESM CMIP5 simulations was supported by the EU-FP7 COMBINE project (Grant 226520). JS was supported by the EU-FP7 CARBOCHANGE project (Grant 284679). We acknowledge the World Climate Research Programme’s Working Group on Coupled Modelling, which is responsible for CMIP, and we thank the climate modeling groups (listed in Table 1 of this paper) for producing and making available their model output. For CMIP, the U.S. Department of Energy’s Program for Climate Model Diagnosis and Intercomparison provides coordinating support and led development of software infrastructure in partnership with the Global Organization for Earth System Science Portals. JT and CR were supported by the Research Council of Norway through the EarthClim (207711/E10) project

    Exposure to airborne bacteria depends upon vertical stratification and vegetation complexity

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    Exposure to biodiverse aerobiomes supports human health, but it is unclear which ecological factors influence exposure. Few studies have investigated near-surface green space aerobiome dynamics, and no studies have reported aerobiome vertical stratification in different urban green spaces. We used columnar sampling and next generation sequencing of the bacterial 16S rRNA gene, combined with geospatial and network analyses to investigate urban green space aerobiome spatio-compositional dynamics. We show a strong effect of habitat on bacterial diversity and network complexity. We observed aerobiome vertical stratification and network complexity that was contingent on habitat type. Tree density, closer proximity, and canopy coverage associated with greater aerobiome alpha diversity. Grassland aerobiomes exhibited greater proportions of putative pathogens compared to scrub, and also stratified vertically. We provide novel insights into the urban ecosystem with potential importance for public health, whereby the possibility of differential aerobiome exposures appears to depend on habitat type and height in the airspace. This has important implications for managing urban landscapes for the regulation of aerobiome exposure

    RNA editing signature during myeloid leukemia cell differentiation

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    Adenosine deaminases acting on RNA (ADARs) are key proteins for hematopoietic stem cell self-renewal and for survival of differentiating progenitor cells. However, their specific role in myeloid cell maturation has been poorly investigated. Here we show that ADAR1 is present at basal level in the primary myeloid leukemia cells obtained from patients at diagnosis as well as in myeloid U-937 and THP1 cell lines and its expression correlates with the editing levels. Upon phorbol-myristate acetate or Vitamin D3/granulocyte macrophage colony-stimulating factor (GM-CSF)-driven differentiation, both ADAR1 and ADAR2 enzymes are upregulated, with a concomitant global increase of A-to-I RNA editing. ADAR1 silencing caused an editing decrease at specific ADAR1 target genes, without, however, interfering with cell differentiation or with ADAR2 activity. Remarkably, ADAR2 is absent in the undifferentiated cell stage, due to its elimination through the ubiquitin–proteasome pathway, being strongly upregulated at the end of the differentiation process. Of note, peripheral blood monocytes display editing events at the selected targets similar to those found in differentiated cell lines. Taken together, the data indicate that ADAR enzymes play important and distinct roles in myeloid cells
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