71 research outputs found
A new variety of purple tomato as a rich source of bioactive carotenoids and its potential health benefits
Carotenoid-rich fractions (CRF) from pulp and peel of a new variety of purple tomato were investigated in
comparison to a Red Cherry variety regarding carotenoids characterization, antioxidant capacity, and inhibition
of proliferation of four tumor cell lines. CRF from peel of Purple tomato contains lutein, lycopene, and β-carotene
up to 6, 1.5, and 2.5 times more than that of Red Cherry and it exhibited the highest antioxidant activity at 400
μg/mL, reaching 82% and 97% in DPPH and ABTS þ assays, respectively. Besides that, the Purple peel showed the
highest scavenging lipoperoxides capacity as well as displayed the highest ferric reducing antioxidant power
compared to the other CRF. In turn, the Red Cherry pulp CRF showed the highest antiproliferative activity against
four tumor cell lines (MCF-7, NCI-H460, HeLa, and HepG2) at non-toxic concentrations. High concentration of
neurosporene, and lycopene in Red Cherry pulp CRF show to be related to the good antiproliferative activity
found on it. Therefore, this new variety of nutrient-rich purple tomato could be explored as well as the commercial
variety Red Cherry, since both are good sources of dietary carotenoids with health-promoting properties.This work was supported by Fundação de Amparo à Pesquisa do
Estado de São Paulo (FAPESP) [grant number 2014/11150-6]; and
Conselho Nacional de Desenvolvimento CientÃfico e Tecnológico (CNPq)
[grant numbers 306722/2012-7, 307040/2014-3, and 150015/2018-6)
from Brazil; and Fundação para a Ciência e a Tecnologia (FCT) for CIMO
[grant numbers Pest OE/AGR/UI0690/2014; SFRH/BPD/68344/2010]
from Portugal.info:eu-repo/semantics/publishedVersio
Ten years-snapshot of the occurrence of emerging contaminants in drinking, surface and ground waters and wastewaters from São Paulo state, Brazil
Emerging contaminants have been considered one of the main concerns for ensuring the quality of water around the world. This work presents the results of 10 years of analyses carried out in the state of São Paulo (Brazil) that has the high population density and intense agricultural and industrial activities. In this work 58 compounds (9 hormones, 14 pharmaceuticals and personal care products, 8 industrial compounds, 17 pesticides and 10 illicit drugs) were determined from 2006 to 2015 in 708 samples including raw and treated sewage, surface and ground and drinking waters. A preliminary risk assessment for aquatic life protection identified potential risks for caffeine, paracetamol, diclofenac, 17α-ethynylestradiol, 17β-estradiol, estriol, estrone, testosterone, triclosan, 4-n-nonylphenol, bisphenol A, atrazine, azoxystrobin, carbendazim, fipronil, imidacloprid, malathion and tebuconazole. Drinking water criteria were available only for 22 compounds and for them no adverse effects were expected at the concentrations found, except for 17β-estradiol
Carbohydrate-derived iminium salt organocatalysts for the asymmetric epoxidation of alkenes
A new family of carbohydrate-based dihydroisoquinolinium salts has been prepared and tested for potential as asymmetric catalysts for the epoxidation of unfunctionalized alkene substrates, providing up to 57% ee in the product epoxides
Preparation and Anti-Corrosive Properties of Cerium Oxide Conversion Coatings on Steel X52
Atropo- and Diastereoselective Construction of Tetracyclic Biphenylazepinium Salts Derived from Aminoalcohols: Use as Catalysts in Enantioselective Asymmetric Epoxidation
Utilizando técnicas de ensino participativas como instrumento de aprendizagem e sensibilização do manejo da lactação para profissionais de enfermagem de uma maternidade
New biphenyl iminium salt catalysts for highly enantioselective asymmetric epoxidation: role of additional substitution and dihedral angle
New biaryl iminium salt catalysts for enantioselective alkene epoxidation containing additional substitution in the heterocyclic ring are reported. The effects upon conformation and enantioselectivity of this additional substitution, and the influence of dihedral angle in these systems, has been investigated using a synthetic approach supported by density functional theory. Enantioselectivities of up to 97% ee were observed
Bovine meat and bone meal is an economically viable alternative in quail feeding in the initial phase
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