671 research outputs found
The Behavioral Analysis Interview: Clarifying the Practice, Theory and Understanding of its Use and Effectiveness
The Behavioral Analysis Interview (BAI) is the only questioning method that has been developed
specifically to help investigators sort those who are likely to be âguiltyâ from those who are
not. In its typical application the BAI is a pre-interrogation interview that is used to focus interrogational
effort; however, it also can be used independently in order to circumscribe investigative
efforts in those cases in which there is a fixed and relatively large number of âsuspectsâ. In this
paper an overview of the BAI process is provided and the findings and limitations of the extant
bodies of field and laboratory research on the BAI are discussed. The paper concludes with suggestions
to guide future research on the BAI
Variation in the quality of meat from Irish steers at the time of slaughter.
End of Project ReportThere is no information on the variation in quality, in particular
tenderness, that exists in Irish Beef nor is there information on the
variation that would remain if optimum practices were imposed at
all stages of the beef production chain. Evaluation of the success of
measures to improve beef consistency requires information on
existing variation and the minimum variation achievable.The objectives
of this project were (i) to establish the variation that exists in
the quality of meat from Irish cattle, (ii) to quantify the minimum
variation in meat quality that can be achieved in a practical beef production
system, (iii) to determine the effects and mechanisms of
additional sources of variation.
The conclusions from this project are:
⢠The M. longissimus dorsi (loin) was found to be more variable
than the M. semimembranosus (topside) for most quality
attributes examined (tenderness, sarcomere length and pH).
The scale of variation within the loin was similar to that
reported by the other research groups within the EU and US.
Heifers were more variable than steers for most attributes,
while there was no consistent classification effect on the
variability of meat quality attributes.
⢠Tenderness was equally variable in meat from genetically similar
steers, managed similarly, compared to commercial steers
randomly selected from a factory lairage but matched for
weight and grade.This was likely a result of both groups being
crossbred beef cattle of similar age, fat score, carcass weight
and managed identically post-mortem. However, variation in
tenderness of both groups was less than that observed in
a survey of commercial throughput (experiment 1). This
decrease is attributed to better pre-and-post-slaughter handling
practices.
⢠The data suggest that selection of sires (within a breed) with
better than average conformation has no deleterious effect on the eating quality of beef of their progeny.A more comprehensive
comparison of sires within a breed and between
breeds is required to confirm the generality of this conclusion.
⢠In a comparison of genotypes, gender and slaughter weights,
there was no evidence that variation around the mean value
for tenderness differed between breeds or liveweights after
14 days ageing. Bulls were more variable than steers for some
quality traits but the variation in tenderness was similar for
bulls and steers after 14 days ageing.
⢠While optimising the management of animals during the pre
and post-slaughter period reduced variation in tenderness,
some residual variation remained. A large percentage of the
residual variation in tenderness (Warner Bratzler shear force)
after 2 and 7 days post-mortem was explained by proteolysis
(breakdown of myofibrillar proteins).Variation in tenderness
(Warner Bratzler shear force) after 2 days post-mortem was
largely explained by phosphates (energy) and proteolysis,
while sensory tenderness was largely explained by phosphates
and glycolytic potential.
⢠Further work is required to reduce residual variation in Irish
beef and to determine the causes of this variation
Studies on Pre-slaughter Handling of Pigs and its Relationship to Meat Quality
End of Project ReportsTwo quality defects of pork which are affected by preslaughter
handling are PSE (Pale Soft Exudative) and DFD (Dark
Firm Dry) meat.
The incidence of PSE pork is mainly a function of the breed of
pig but short-term stressful handling before slaughter and feeding
too close to slaughter are also involved. DFD meat is a result of
prolonged stressful handling. PSE meat is pale and uneven in
colour and exudes fluid making it unattractive in the retail display
while dark meat appears stale and is prone to bacterial spoilage.
After slaughter muscle metabolism continues and muscle glycogen
is converted to lactic acid reducing meat pH. Prolonged stress
results in glycogen depletion, pre-slaughter feeding results in
elevated levels. Colour may be assessed subjectively by eye or
objectively by a meter colour but pH of the meat is closely related
to colour and measurement of pH at 45 minutes post-slaughter is
frequently used to predict ultimate colour and pH.
The objective of this study was to examine pre-slaughter handling
practices and their relationship with meat quality (pH, colour).
In the first trial, a survey of the amounts of stomach contents in
pigs at slaughter in two factories found similar amounts to
comparable surveys in France and the UK. It was concluded that
most pigs had been fasted for an adequate time before delivery.
The relationship between the amount of stomach contents and
meat quality in this survey was poor.
In the second trial, pigs from the Moorepark herd fed by either a
computerised wet feeding system or an ad libitum dry feed system
were slaughtered after overnight fasting or with feed available up
to loading for transport to the factory, two to three hours before
slaughter. There was no difference between feeding systems in
meat colour or pH but fasted pigs, on both feeding systems, had
darker meat and meat of a higher pH.
In the third and fourth trials a survey of transport vehicles was
carried out and meat quality of pigs delivered in modern and old-type vehicles was compared. Most trucks examined (78%) were
four years old or more. Few had modern hydraulic lifting gear for
the top decks. Space allowances during transportation were
generally adequate but delays in unloading could, in warm weather,
cause stress on pigs. There was little evidence for an effect of
vehicle on meat quality parameters but day to day variation in
carcass temperature and pH suggested a need for further research
on factory influences on meat quality.
Feeding of Magneium Aspartate to pigs for the last 5 days prior
to slaughter has been shown, in Australia, to have a beneficial
effect on meat colour and drip loss. In the final trial in this study
Mg Asp had no effect on meat quality parameters.European Union Structural Funds (EAGGF
Questions, conjectures, and data about multiplicity lists for trees
We review and discuss a number of questions and conjectures about multiplicity lists occurring among real symmetric matrices whose graph is a tree. Our investigation is aided by a new electronic database containing all multiplicity lists for trees on fewer than 12 vertices. Some questions and conjectures are familiar and some are new, and new information is given about several. (C) 2016 Elsevier Inc. All rights reserved
The wellâworn route revisited: Striatal and hippocampal system contributions to familiar route navigation
Classic research has shown a division in the neuroanatomical structures that support flexible (e.g., shortâcutting) and habitual (e.g., familiar route following) navigational behavior, with hippocampalâcaudate systems associated with the former and putamen systems with the latter. There is, however, disagreement about whether the neural structures involved in navigation process particular forms of spatial information, such as associations between constellations of cues forming a cognitive map, versus single landmarkâaction associations, or alternatively, perform particular reinforcement learning algorithms that allow the use of different spatial strategies, soâcalled modelâbased (flexible) or modelâfree (habitual) forms of learning. We sought to test these theories by asking participants (N = 24) to navigate within a virtual environment through a previously learned, 9âjunction route with distinctive landmarks at each junction while undergoing functional magnetic resonance imaging (fMRI). In a series of probe trials, we distinguished knowledge of individual landmarkâaction associations along the route versus knowledge of the correct sequence of landmarkâaction associations, either by having absent landmarks, or âoutâofâsequenceâ landmarks. Under a mapâbased perspective, sequence knowledge would not require hippocampal systems, because there are no constellations of cues available for cognitive map formation. Within a learningâbased model, however, responding based on knowledge of sequence would require hippocampal systems because prior context has to be utilized. We found that hippocampalâcaudate systems were more active in probes requiring sequence knowledge, supporting the learningâbased model. However, we also found greater putamen activation in probes where navigation based purely on sequence memory could be planned, supporting models of putamen function that emphasize its role in action sequencing
New Class of Precision Antimicrobials Redefines Role of Clostridium difficile S-layer in Virulence and Viability
There is a medical need for antibacterial agents that do not damage the resident gut microbiota or promote the spread of antibiotic resistance. We recently described a prototypic precision bactericidal agent, Av-CD291.2, which selectively kills specific Clostridium difficile strains and prevents them from colonizing mice. We have since selected two Av-CD291.2âresistant mutants that have a surface (S)-layerânull phenotype due to distinct point mutations in the slpA gene. Using newly identified bacteriophage receptor binding proteins for targeting, we constructed a panel of Avidocin-CDs that kills diverse C. difficile isolates in an S-layer sequence-dependent manner. In addition to bacteriophage receptor recognition, characterization of the mutants also uncovered important roles for S-layer protein A (SlpA) in sporulation, resistance to innate immunity effectors, and toxin production. Surprisingly, S-layerânull mutants were found to persist in the hamster gut despite a complete attenuation of virulence. These findings suggest antimicrobials targeting virulence factors dispensable for fitness in the host force pathogens to trade virulence for viability and would have clear clinical advantages should resistance emerge. Given their exquisite specificity for the pathogen, Avidocin-CDs have substantial therapeutic potential for the treatment and prevention of C. difficile infections
Pre- and postnatal exposure to secondhand tobacco smoke and body composition at 12âyears: periods of susceptibility
Objective: The study aimed to identify periods of heightened susceptibility to the effects of pre- and postnatal secondhand tobacco smoke (SHS) exposure on body composition at age 12âyears. Methods: The study used data from 217 children from the Health Outcomes and Measures of the Environment (HOME) Study, a prospective cohort in Cincinnati, Ohio. Using multiple informant models, the study estimated associations of maternal serum cotinine (16 and 26 weeks of pregnancy) and child serum cotinine concentrations (at age 12, 24, 36, and 48 months) with measures of body composition obtained with anthropometry and dual-energy x-ray absorptiometry at 12âyears. We examined whether there were differences between these associations for pre- and postnatal exposure periods and potential effect measure modification by sex.Results: Postnatal cotinine concentrations were associated with higher weight, BMI, body fat and lean mass, waist circumference, and visceral, android, and gynoid fat. Each 10-fold increase in postnatal cotinine was associated with 76% increased risk of overweight or obesity (95% CI: 1.13-2.75). Associations between prenatal concentrations and measures of body composition at 12âyears were generally null.Conclusions: Postnatal exposure to SHS may increase adolescent adiposity and lean mass. Future studies should determine whether early-life exposures to SHS are associated with other cardiometabolic risk markers.Objective: The study aimed to identify periods of heightened susceptibility to the effects of pre- and postnatal secondhand tobacco smoke (SHS) exposure on body composition at age 12âyears. Methods: The study used data from 217 children from the Health Outcomes and Measures of the Environment (HOME) Study, a prospective cohort in Cincinnati, Ohio. Using multiple informant models, the study estimated associations of maternal serum cotinine (16 and 26 weeks of pregnancy) and child serum cotinine concentrations (at age 12, 24, 36, and 48 months) with measures of body composition obtained with anthropometry and dual-energy x-ray absorptiometry at 12âyears. We examined whether there were differences between these associations for pre- and postnatal exposure periods and potential effect measure modification by sex.Results: Postnatal cotinine concentrations were associated with higher weight, BMI, body fat and lean mass, waist circumference, and visceral, android, and gynoid fat. Each 10-fold increase in postnatal cotinine was associated with 76% increased risk of overweight or obesity (95% CI: 1.13-2.75). Associations between prenatal concentrations and measures of body composition at 12âyears were generally null.Conclusions: Postnatal exposure to SHS may increase adolescent adiposity and lean mass. Future studies should determine whether early-life exposures to SHS are associated with other cardiometabolic risk markers.National Institute of Environmental Health Sciences. Grant Numbers: P01 ES011261, R01 ES014575, R01 ES015517National Institute of Environmental Health Sciences. Grant Numbers: P01 ES011261, R01 ES014575, R01 ES015517SIS
Prenatal Phthalate Exposures and Body Mass Index Among 4- to 7-Year-old Children: A Pooled Analysis
Phthalates are hypothesized to cause obesity, but few studies have assessed whether prenatal phthalate exposures are related to childhood body mass index (BMI)
A comparison of two cases of low-latitude thundersnow
http://solberg.snr.missouri.edu/gcc/Two cases of low-latitude snow with lightning are studied to determine their characteristics. Both cases had synoptic-scale origins, but also featured smaller-scale influences (e. g. orographic lift and elevated instability).The first event occurred in the Southern Hemisphere and was a late winter case that developed under the influence of underlying orography. Lightning was plentiful in that event (94 cloud-to-ground flashes in the region), but snow accumulations were not significant. Lightning flashes of negative polarity dominated this case, with a mean peak amplitude of -43.2 kA. The second event was a Northern Hemisphere case of elevated convection, with frontogenesis beneath an extended layer of potential instability. Appreciable lightning occurred with this event as well (706 cloud-to-ground flashes in the region), and snow accumulations were significant over a broad area. Lightning flashes of negative polarity dominated this case also, with a mean peak amplitude of -23.7 kA. Each of these events is worthy of further scrutiny, as studies of such storms do not appear often in the literature. Indeed, such warm, subtropical regions are often unprepared for the effects of just a little snow or ice accumulation. Future forecasters can anticipate better such anomalous events by looking for these broad features: 1) significant and well-defined synoptic-scale weather systems at low latitudes, 2) a strong baroclinic zone with a well-defined (âĽ60 ms-1) jet structure aloft, 3) cold air of appreciable depth and areal extent drawn much closer to the equator than is typical, and 4) a moist neutral to conditionally unstable layer above the frontal zone
Trees Grow on Money: Urban Tree Canopy Cover and Environmental Justice
This study examines the distributional equity of urban tree canopy (UTC) cover for Baltimore, MD, Los Angeles, CA, New York, NY, Philadelphia, PA, Raleigh, NC, Sacramento, CA, and Washington, D.C. using high spatial resolution land cover data and census data. Data are analyzed at the Census Block Group levels using Spearman\u27s correlation, ordinary least squares regression (OLS), and a spatial autoregressive model (SAR). Across all cities there is a strong positive correlation between UTC cover and median household income. Negative correlations between race and UTC cover exist in bivariate models for some cities, but they are generally not observed using multivariate regressions that include additional variables on income, education, and housing age. SAR models result in higher r-square values compared to the OLS models across all cities, suggesting that spatial autocorrelation is an important feature of our data. Similarities among cities can be found based on shared characteristics of climate, race/ethnicity, and size. Our findings suggest that a suite of variables, including income, contribute to the distribution of UTC cover. These findings can help target simultaneous strategies for UTC goals and environmental justice concerns
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