1,310 research outputs found
Food System Sustainability across Scales: A Proposed Local-To-Global Approach to Community Planning and Assessment
Interest in food systems sustainability is growing, but progress toward them is slow. This research focuses on three interrelated challenges that hinder progress. First, prevailing visions lack a concrete definition of sustainability. Second, global level conceptions fail to guide responses at the local level. Third, these deficiencies may lead to conflicting initiatives for addressing sustainable food systems at the community level that slow collective progress. The purpose of this article is to (1) describe the development of a framework for assessing food system sustainability which accommodates local-level measurement in the context of broader national and global scale measures; and (2) to propose a process that supports community determinacy over localized progress toward sustainable food systems. Using a modified Delphi Inquiry process, we engaged a diverse, global panel of experts in describing “success” with respect to sustainable food systems, today’s reality, and identifying key indicators for tracking progress towards success. They were asked to consider scale during the process in order to explore locally relevant themes. Data were analyzed using the Framework for Strategic Sustainable Development (FSSD) to facilitate a comprehensive and systematic exploration of key themes and indicators. Key results include a framework of indicator themes that are anchored in a concrete definition of sustainability, stable at national and global scales while remaining flexible at the local scale to accommodate contextual needs. We also propose a process for facilitating community-level planning for food system sustainability that utilizes this indicator framework. The proposed process is based on insights from the research results, as well as from previous research and experience applying the FSSD at a community level; it bears promise for future work to support communities to determine their own pathways, while contributing to a more coordinated whole
qtl.outbred: Interfacing outbred line cross data with the R/qtl mapping software
<p>Abstract</p> <p>Background</p> <p><b>qtl.outbred </b>is an extendible interface in the statistical environment, R, for combining quantitative trait loci (QTL) mapping tools. It is built as an umbrella package that enables outbred genotype probabilities to be calculated and/or imported into the software package R/<b>qtl</b>.</p> <p>Findings</p> <p>Using <b>qtl.outbred</b>, the genotype probabilities from outbred line cross data can be calculated by interfacing with a new and efficient algorithm developed for analyzing arbitrarily large datasets (included in the package) or imported from other sources such as the web-based tool, GridQTL.</p> <p>Conclusion</p> <p><b>qtl.outbred </b>will improve the speed for calculating probabilities and the ability to analyse large future datasets. This package enables the user to analyse outbred line cross data accurately, but with similar effort than inbred line cross data.</p
Физическая и функциональная подготовленность студентов, занимающихся в секции мини-футбола
ФИЗИЧЕСКАЯ ПОДГОТОВЛЕННОСТЬМИНИ-ФУТБОЛДВИГАТЕЛЬНАЯ НАГРУЗКА, МЕТОДЫ ИССЛЕДОВАНИЯОЦЕНОЧНЫЕ ИССЛЕДОВАНИЯСТУДЕНТЫ МЕДИЦИНСКИХ УЧЕБНЫХ ЗАВЕДЕНИЙБЕГСКОРОСТНО-СИЛОВЫЕ КАЧЕСТВ
Taxometric Investigation of PTSD: Data From Two Nationally Representative Samples
Current psychiatric nosology depicts posttraumatic stress disorder (PTSD) as a discrete diagnostic category. However, only one study has examined the latent structure of PTSD, and this study suggested that PTSD may be more accurately conceptualized as an extreme reaction to traumatic life events rather than a discrete clinical syndrome. To build on the existing literature base, the present research examined the latent structure of posttraumatic stress reactions by applying three taxometric procedures (MAXEIG, MAMBAC, and L-Mode) to data collected from large nationally representative samples of women (ns = 2684 and 3033) and adolescents (n = 3775). Results consistently provided evidence for a dimensional PTSD solution across samples and statistical procedures. These findings have important implications for the theory, assessment, and investigation of posttraumatic stress reactions
Undersøkelser for å styrke modeller knyttet til beslutningsstøtte for tiltak mot forurensede sedimenter i Grenlandsfjordene
Årsliste 2009I forbindelse med problemstillingene om sedimenttiltak i Grenlandsfjordene, er undersøkelser utført for å styrke beslutningsgrunnlaget for eventuelle tiltak mot dioksinforurensede sedimenter i fjordområdet. Dette arbeidet har bestått i en avansert kalibrering av den såkalte SedFlex-modellen for å styrke usikkerhetsestimatene i modellsimuleringene. Betydningen av skipsoppvirvling ved Herøya for dioksinutviklingen i Frierfjorden er modellert. Videre er tykkelsen på det aktive, bioturberte overflatelaget på 39 stasjoner i Grenlandsfjordene bestemt ved hjelp av SPI-sedimentkameraet. Tre stasjoner for ”overvåket naturlig forbedring” er blitt opprettet hvor den feltmessige variansen er beskrevet og utsagnskraften i et overvåkingsprogram beregnet. Transport av dioksiner fra Frierfjorden til fjordområdet utenfor er beregnet både gjennom direkte målinger ved bruk av passive prøvetakere og ved simuleringer i SedFlex-modellen.Norsk Hydr
Genetic dissection of a model complex trait using the Drosophila Synthetic Population Resource
Genetic dissection of complex, polygenic trait variation is a key goal of medical and evolutionary genetics. Attempts to identify genetic variants underlying complex traits have been plagued by low mapping resolution in traditional linkage studies, and an inability to identify variants that cumulatively explain the bulk of standing genetic variation in genome-wide association studies (GWAS). Thus, much of the heritability remains unexplained for most complex traits. Here we describe a novel, freely available resource for the Drosophila community consisting of two sets of recombinant inbred lines (RILs), each derived from an advanced generation cross between a different set of eight highly inbred, completely resequenced founders. The Drosophila Synthetic Population Resource (DSPR) has been designed to combine the high mapping resolution offered by multiple generations of recombination, with the high statistical power afforded by a linkage-based design. Here, we detail the properties of the mapping panel of >1600 genotyped RILs, and provide an empirical demonstration of the utility of the approach by genetically dissecting alcohol dehydrogenase (ADH) enzyme activity. We confirm that a large fraction of the variation in this classic quantitative trait is due to allelic variation at the Adh locus, and additionally identify several previously unknown modest-effect trans-acting QTL (quantitative trait loci). Using a unique property of multiparental linkage mapping designs, for each QTL we highlight a relatively small set of candidate causative variants for follow-up work. The DSPR represents an important step toward the ultimate goal of a complete understanding of the genetics of complex traits in the Drosophila model system.This work was supported by the following NIH R01 grants: RR024862 to S.J.M. and A.D.L., GM085260 to S.J.M., GM085251 to A.D.L., GM078338 to S.S., and GM074244 to K.W.B
Child developmental delay and socio-economic disadvantage in Australia: A longitudinal study
Socio-economic inequalities in adult and child health in Australia have been an issue of national concern. While a large body of data has discussed adult health, there have been relatively few Australian reports of socioeconomic inequalities in child health. This occurs in a context where there have been increases in the proportion of Australian children living in poverty and where there has been an increased interest in child developmental delay as an indicator of child health status. This paper reports the result of a longitudinal study of pregnancy outcomes and one indicator of child health, namely child developmental delay. Three indicators of socio-economic status (chronic socio-economic disadvantage, mother's education, family income) were used to predict child developmental delays observed some 5: years after the study commenced. Mothers who had the lowest socio-economic status (using any of the indicators) had substantially higher rates of children manifesting developmental delays
The point of maximum curvature as a marker for physiological time series
We present a geometric analysis of the model of Stirling. In particular we analyze the curvature of a heart rate time series in response to a step like increment in the exercise intensity. We present solutions for the point of maximum curvature which can be used as a marker of physiological interest. This marker defines the point after which the heart rate no longer continues to rapidly rise and instead follows either a steady state or slow rise. These methods are then applied to find analytic solutions for a mono exponential model which is commonly used in the literature to model the response to a moderate exercise intensity. Numerical solutions are then found for the full model and parameter values presented in Stirling
A demonstration of an affinity between pyrite and organic matter in a hydrothermal setting
One of the key-principles of the iron-sulphur world theory is to bring organic molecules close enough to interact with each other, using the surface of pyrite as a substrate in a hydrothermal setting. The present paper explores the relationship of pyrite and organic matter in a hydrothermal setting from the geological record; in hydrothermal calcite veins from Carboniferous limestones in central Ireland. Here, the organic matter is accumulated as coatings around, and through, pyrite grains. Most of the pyrite grains are euhedral-subhedral crystals, ranging in size from ca 0.1-0.5 mm in diameter, and they are scattered throughout the matrix of the vein calcite. The organic matter was deposited from a hydrothermal fluid at a temperature of at least 200°C, and gives a Raman signature of disordered carbon. This study points to an example from a hydrothermal setting in the geological record, demonstrating that pyrite can have a high potential for the concentration and accumulation of organic materials
Oxygen-deficient water zones in the Baltic Sea promote uncharacterized Hg methylating microorganisms in underlying sediments
Human-induced expansion of oxygen-deficient zones can have dramatic impacts on marine systems and its resident biota. One example is the formation of the potent neurotoxic methylmercury (MeHg) that is mediated by microbial methylation of inorganic divalent Hg (Hg-II) under oxygen-deficient conditions. A negative consequence of the expansion of oxygen-deficient zones could be an increase in MeHg production due to shifts in microbial communities in favor of microorganisms methylating Hg. There is, however, limited knowledge about Hg-methylating microbes, i.e., those carrying hgc genes critical for mediating the process, from marine sediments. Here, we aim to study the presence of hgc genes and transcripts in metagenomes and metatranscriptomes from four surface sediments with contrasting concentrations of oxygen and sulfide in the Baltic Sea. We show that potential Hg methylators differed among sediments depending on redox conditions. Sediments with an oxygenated surface featured hgc-like genes and transcripts predominantly associated with uncultured Desulfobacterota (OalgD group) and Desulfobacterales (including Desulfobacula sp.) while sediments with a hypoxic-anoxic surface included hgc-carrying Verrucomicrobia, unclassified Desulfobacterales, Desulfatiglandales, and uncharacterized microbes. Our data suggest that the expansion of oxygen-deficient zones in marine systems may lead to a compositional change of Hg-methylating microbial groups in the sediments, where Hg methylators whose metabolism and biology have not yet been characterized will be promoted and expand
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