Cyclic AMP metabolism and adenylate cyclase concentration in patients with advanced hepatic cirrhosis

Glucagon was tested for its effect on plasma adenosine 3′,5′-cyclic monophosphate (cyclic AMP), insulin, and glucose in healthy subjects and in patients with advanced cirrhosis of the liver. In the normal subjects, intravenous infusion of glucagon caused a significant increase in plasma cyclic AMP, glucose, and insulin. In advanced cirrhotics, plasma cyclic AMP, glucose, and insulin did not increase. Adenylate cyclase concentration was measured in liver tissue from end stage cirrhotic patients and from brain-dead organ donors whose cardiovascular function was maintained in a stable state. Basal and total adenylate cyclase concentration were not different in the two groups. Adenylate cyclase from the livers of advanced cirrhotics was, however, significantly less responsive to glucagon stimulation than was that from donor livers. Hepatocytes in advanced cirrhosis have abnormal metabolic behavior characterized by abnormal adenylate cyclase-cyclic AMP response to hormonal stimulation. © 1978

EELV Incorporates GPS Metric Tracking as a Range Tracking Source

ITC/USA 2012 Conference Proceedings / The Forty-Eighth Annual International Telemetering Conference and Technical Exhibition / October 22-25, 2012 / Town and Country Resort & Convention Center, San Diego, CaliforniaCurrently, the Evolved Expendable Launch Vehicle (EELV) utilizes a communications, tracking, and control system that was developed at the inception of the space launch industry. The current system operation and large ground footprint have driven the United States Air Force (USAF) to embark on an initiative known as the Future Flight Safety System (FFSS) that will lead into a Space Based Range Concept. An important phase of FFSS is the implementation of Global Positioning System Metric Tracking (GPS MT) on all launch vehicles. Working in partnership, United Launch Alliance (ULA) and their USAF EELV customer have developed a common GPS MT solution for both the Atlas V and Delta IV Launch Vehicles.International Foundation for TelemeteringProceedings from the International Telemetering Conference are made available by the International Foundation for Telemetering and the University of Arizona Libraries. Visit http://www.telemetry.org/index.php/contact-us if you have questions about items in this collection

A treatise on the preparation and delivery of sermons,: by John A. Broadus ...

xv, 17-514 p ; 20 cm.Electronic text and image data. Ann Arbor, Mich. : University of Michigan, Digital Library Initiatives, 1996. Includes both TIFF files and keyword searchable text. [Making of America] This volume is made possible by a grant from the Andrew W. Mellon Foundation