454 research outputs found

    Standardized Symbology for MSP, delivered Styled Layer Descriptor for MSP INSPIRE Data model

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    Es una presentación oral sobre los trabajos realizados por personal del IEO, en relación a la elaboración de una "Style Layer Descriptor" SLD, que permite asociar una simbología común a los objetos existentes en el MSP INSPIRE Data model, desarrollado por ECOACUA.Se trata de una comunicación oral presentada en el Workshop MS11: Ready to use MSP products, enmarcado en el proyecto MSP-OR. Advancing Maritime Spatial Planning in Outermost Regions. En este workshop se muestras productos generados en otros proyectos de MSP que son de utilidad. En esta presentación se exponen los trabajos de elaboración de una SLD (Style Layer Descriptor) con el objetivo de estandarizar la simbología para el MSP INSPIRE Data model, realizados en el proyecto MARSP.MINISTERIO DE CIENCIA E INNOVACIÓN. CSIC. CN INSTITUTO ESPAÑOL DE OCEANOGRAFÍA. UNION EUROPEA

    Maritime Spatial Planning INSPIRE data model

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    Poster para CongresoThe Maritime Spatial Planning (MSP) INSPIRE data model concept has been developing from 2014, applying Infrastructure for spatial information in Europe Directive 2007/2/EC (INSPIRE) data management concepts for marine planning, through the Marine Pilot project (EC Joint Research Centre 2014-2016) and continuing with the PLASMAR project (INTERREG–V 2017-2020). The results and findings delivered have been published in the paper “Maritime spatial planning supported by infrastructure for spatial information in Europe (INSPIRE)” (Abramic et al., 2018). Currently, there are difficulties in harmonising products, visions, maps and frameworks of maritime spatial plans delivered by countries sharing the same marine (sub)region. This is mainly due to the fact that maritime plans do not use a common symbology and data structure to describe maritime activities. A solution for this issue is to apply on a marine spatial plans, INSPIRE standards for data sets, layers and portrayals. The MarSP project was a perfect opportunity to finalise conceptual data model development and, what is more important, to test results applying it on the real use cases, developed in the Macaronesia (Azores, Madeira, Canaries) MSP process. Initially, the INSPIRE data model for terrestrial planning (Planned Land Use, Figure 1) was tested to see if it could be applied for MSP. Tests pointed out that the terrestrial data model is robust, and can map MSP’s, but it tends to lose detail and specific information on marine uses. To be applied for MSP, the Planned Land Use data model needs to be adapted for planning of the maritime activities in the marine space. Conceptual model was analyzed, adapted, applying data modeling techniques, adjusting for MSP requirements: 1. Developed conceptual MSP data model, extending Planned Land use, using Unified Model Language (Figure 2); 2. Extending spatial scope of the data model - from two-dimensional land planning to the three dimensions planning. Extended structure includes maritime activities within the sea surface, water column, seabed and subsoil, when land model consists mainly of land surface planning; 3. Developed specific maritime uses classification (including register), extending Hierarchical INSPIRE Land Use classification (HILUCS); 4. Developed MSP data model templates, using simplified and feature complex spatial data architectures. Different type of codification templates, for advanced, standard and rookie GIS users (gml, GeoPackage, Shapfile, available at Canaries MSP platform); 5. Styled Layer Descriptor (color & simbology layout) for MSP, based on International Hydrographic Organization standards. 6. Data specification document v1.0 for Maritime Spatial Planning INSPIRE data model MarSP 2nd capacity building workshop was a great opportunity to test MSP data model results. Participants were trained on how to apply MSP data model on selected use case (Madeira MSP draft), during the “hands on” session, discussing potential issues and technical solutions.MarS

    Promoting FAIRness in marine data at Centro Nacional Instituto Español de Oceanografía

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    The Spanish Institute of Oceanography is responsible, among other aspects, for scienti c and technical advice for the Government's sheries policy as well as for the protection and sustainability of the marine environment. In this task, it generates a large amount of oceanographic data characterized by its spatial dispersion during acquisition as well as by its di erent typology. The purpose of both the National Oceanographic Data Center and the GIS team is to safeguard data and to disclose what data exists and where, how and when it has been acquired and, in addition, to provide access to that data through the collaboration with di erent international data infrastructures like EMODnet or SeaDataNet. To this end, the data and metadata are subjected to quality control and formatted for integration into a national Spatial Data Infrastructure (SDI). This SDI has a GeoNetwork catalogue with ~ 1750 oceanographic campaigns, together with (meta)data and services that are continuously being revised and incorporated. All this with the ultimate goal of making the data increasingly FAIR

    GAA Deficiency in Pompe Disease Is Alleviated by Exon Inclusion in iPSC-Derived Skeletal Muscle Cells

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    Pompe disease is a metabolic myopathy caused by deficiency of the acid α-glucosidase (GAA) enzyme and results in progressive wasting of skeletal muscle cells. The c.-32-13T>G (IVS1) GAA variant promotes exon 2 skipping during pre-mRNA splicing and is the most common variant for the childhood/adult disease form. We previously identified antisense oligonucleotides (AONs) that promoted GAA exon 2 inclusion in patient-derived fibroblasts. It was unknown how these AONs would affect GAA splicing in skeletal muscle cells. To test this, we expanded induced pluripotent stem cell (iPSC)-derived myogenic progenitors and differentiated these to multinucleated myotubes. AONs restored splicing in myotubes to a similar extent as in fibroblasts, suggesting that they act by modulating the action of shared splicing regulators. AONs targeted the putative polypyrimidine tract of a cryptic splice acceptor site that was part of a pseudo exon in GAA intron 1. Blocking of the cryptic splice donor of the pseudo exon with AONs likewise promoted GAA exon 2 inclusion. The simultaneous blocking of the cryptic acceptor and cryptic donor sites restored the majority of canonical splicing and alleviated GAA enzyme deficiency. These results highlight the relevance of cryptic splicing in human disease and its potential as therapeutic target for splicing modulation using AONs

    Learning difficulties : a portuguese perspective of a universal issue

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    In this article we present findings of a study that was conducted with the purpose of deepening the knowledge about the field of learning difficulties in Portugal. Therefore, within these findings we will discuss across several cultural boundaries, themes related with the existence of learning difficulties as a construct, the terminology, the political, social and scientific influences on the field, and the models of identification and of ongoing school support for students. While addressing the above-mentioned themes we will draw attention to the different, yet converging, international understandings of learning difficulties

    How does neighbourhood socio-economic status affect the interrelationships between functioning dimensions in first episode of psychosis? A network analysis approach

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    The links between psychosis and socio-economic disadvantage have been widely studied. No previous study has analysed the interrelationships and mutual influences between functioning dimensions in first episode of psychosis (FEP) according to their neighbourhood household income, using a multidimensional and transdiagnostic perspective. 170 patients and 129 controls, participants in an observational study (AGES-CM), comprised the study sample. The WHO Disability Assessment Schedule (WHODAS 2.0) was used to assess functioning, whereas participants' postcodes were used to obtain the average household income for each neighbourhood, collected by the Spanish National Statistics Institute (INE). Network analyses were conducted with the aim of defining the interrelationships between the different dimensions of functioning according to the neighbourhood household income. Our results show that lower neighbourhood socioeconomic level is associated with lower functioning in patients with FEP. Moreover, our findings suggest that “household responsibilities” plays a central role in the disability of patients who live in low-income neighbourhoods, whereas “dealing with strangers” is the most important node in the network of patients who live in high-income neighbourhoods. These results could help to personalize treatments, by allowing the identification of potential functioning areas to be prioritized in the treatment of FEP according to the patient's neighbourhood characteristic

    Update on the correlation of the highest energy cosmic rays with nearby extragalactic matter

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    Data collected by the Pierre Auger Observatory through 31 August 2007 showed evidence for anisotropy in the arrival directions of cosmic rays above the Greisen-Zatsepin-Kuz'min energy threshold, \nobreak{6×10196\times 10^{19}eV}. The anisotropy was measured by the fraction of arrival directions that are less than 3.13.1^\circ from the position of an active galactic nucleus within 75 Mpc (using the V\'eron-Cetty and V\'eron 12th12^{\rm th} catalog). An updated measurement of this fraction is reported here using the arrival directions of cosmic rays recorded above the same energy threshold through 31 December 2009. The number of arrival directions has increased from 27 to 69, allowing a more precise measurement. The correlating fraction is (386+7)(38^{+7}_{-6})%, compared with 2121% expected for isotropic cosmic rays. This is down from the early estimate of (6913+11)(69^{+11}_{-13})%. The enlarged set of arrival directions is examined also in relation to other populations of nearby extragalactic objects: galaxies in the 2 Microns All Sky Survey and active galactic nuclei detected in hard X-rays by the Swift Burst Alert Telescope. A celestial region around the position of the radiogalaxy Cen A has the largest excess of arrival directions relative to isotropic expectations. The 2-point autocorrelation function is shown for the enlarged set of arrival directions and compared to the isotropic expectation.Comment: Accepted for publication in Astroparticle Physics on 31 August 201
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