Continuous Queries and Real-time Analysis of Social Semantic Data with C-SPARQL

Abstract. Social semantic data are becoming a reality, but apparently their streaming nature has been ignored so far. Streams, being unbounded sequences of time-varying data elements, should not be treated as persistent data to be stored “forever ” and queried on demand, but rather as transient data to be consumed on the fly by queries which are registered once and for all and keep analyzing such streams, producing answers triggered by the streaming data and not by explicit invocation. In this paper, we propose an approach to continuous queries and realtime analysis of social semantic data with C-SPARQL, an extension of SPARQL for querying RDF streams

Influence Of Stimulus Frequency On Blockade Induced By Pancuronium And Rocuronium: Study On Rats Phrenic Nerve-diaphragm Preparation.

To evaluate the influence of two stimulation frequencies on the installation of neuromuscular blockade produced by pancuronium and rocuronium on the rat diaphragm. Diaphragms were submitted to an indirect frequency stimulation of 0.1 and 1 Hz (Groups I and II, respectively). Subgroups were formed (n=5) according to the neuromuscular blocker employed (pancuronium-2 microg/ml and rocuronium-4 microg/ml). The twitch height depression was evaluated at 5, 15 and 30 minutes after adding the neuromuscular blocker. The decrease in twitch height was greater (p<0.01) with a frequency of 1 Hz at all time periods studied both in preparations that are blocked with pancuronium and in those that are blocked with rocuronium. The frequency of stimulation interferes significantly with the installation of neuromuscular blockade produced by pancuronium and rocuronium, since the reduction in amplitude of the rat diaphragm response was greater for 1 Hz frequencies, at all periods studied.22446-5

Influência da freqüência de estímulos no bloqueio neuromuscular produzido pelo pancurônio e rocurônio: estudo em preparação nervo frênico-diafragma de ratos

PURPOSE: To evaluate the influence of two stimulation frequencies on the installation of neuromuscular blockade produced by pancuronium and rocuronium on the rat diaphragm. METHODS: Diaphragms were submitted to an indirect frequency stimulation of 0.1 and 1Hz (Groups I and II, respectively). Subgroups were formed (n=5) according to the neuromuscular blocker employed (pancuronium-2µg/ml and rocuronium-4µg/ml). The twitch height depression was evaluated at 5, 15 and 30 minutes after adding the neuromuscular blocker. RESULTS: The decrease in twitch height was greater (p<0.01) with a frequency of 1Hz at all time periods studied both in preparations that are blocked with pancuronium and in those that are blocked with rocuronium. CONCLUSION: The frequency of stimulation interferes significantly with the installation of neuromuscular blockade produced by pancuronium and rocuronium, since the reduction in amplitude of the rat diaphragm response was greater for 1Hz frequencies, at all periods studied.OBJETIVO: Avaliar a influência de duas freqüências de estimulação na instalação do bloqueio neuromuscular induzido por pancurônio e rocurônio em diafragma de ratos. MÉTODOS: Os diafragmas foram submetidos a uma freqüência de estimulação indireta de 0.1 e 1Hz (Grupos I e II, respectivamente). Os animais foram divididos em subgrupos (n=5) de acordo com o bloqueador neuromuscular a ser utilizado (pancurônio-2µg/mL e rocurônio-4µg/mL). A amplitude das respostas musculares foi avaliada 5, 15 e 30 minutos após a adição do bloqueador neuromuscular à preparação. RESULTS: A redução na intensidade da contração foi maior (p<0.01) com a freqüência de 1Hz em todos os tempos avaliados para as preparações contendo pancurônio e rocurônio CONCLUSION: A freqüência de estímulo interfere significativamente na instalação do bloquio neuromuscular produzido por pancurônio e rocurônio, uma vez que a redução na amplitude da resposta do diafragma foi maior para a freqüência de 1Hz em todos os períodos estudados.44645

ANÁLISE DAS PROPRIEDADES DO CONCRETO ESTRUTURAL UTILIZANDO A CINZA PESADA DO BAGAÇO DA CANA-DE AÇÚCAR

O Brasil lidera hoje como o maior produtor de etanol e açúcar no mundo, sendo consequentemente o maior produtor de cana-de-açúcar. Com isso, para tamanha produção, são gerados grandes volumes de resíduos que se buscam empregá-los para a redução do volume de descarte no meio ambiente. O bagaço é o resíduo da produção de etanol e açúcar, em que é empregado para a cogeração de energia elétrica, resultando em um resíduo final: as cinzas. As mesmas são descartadas em aterros ocupando um grande volume e gerando um maior impacto ambiental. Este projeto teve como objetivo confeccionar o concreto com substituição parcial de agregado miúdo pelas cinzas pesadas do bagaço da cana-de-açúcar, com diferentes teores de substituição (0%, 10%, 20%, 30% e 40%), em massa. Os concretos foram caracterizados no estado fresco quanto à consistência, e no estado endurecido quanto a resistência à compressão e absorção de água. Os resultados constatam que a substituição da areia por CBC foram satisfatórios visto que, quanto maior quantidade de CBC mais resistência foi apresentada

ANÁLISE DAS PROPRIEDADES DO CONCRETO ESTRUTURAL UTILIZANDO A CINZA PESADA DO BAGAÇO DA CANA-DE AÇÚCAR

O Brasil lidera hoje como o maior produtor de etanol e açúcar no mundo, sendo consequentemente o maior produtor de cana-de-açúcar. Com isso, para tamanha produção, são gerados grandes volumes de resíduos que se buscam empregá-los para a redução do volume de descarte no meio ambiente. O bagaço é o resíduo da produção de etanol e açúcar, em que é empregado para a cogeração de energia elétrica, resultando em um resíduo final: as cinzas. As mesmas são descartadas em aterros ocupando um grande volume e gerando um maior impacto ambiental. Este projeto teve como objetivo confeccionar o concreto com substituição parcial de agregado miúdo pelas cinzas pesadas do bagaço da cana-de-açúcar, com diferentes teores de substituição (0%, 10%, 20%, 30% e 40%), em massa. Os concretos foram caracterizados no estado fresco quanto à consistência, e no estado endurecido quanto a resistência à compressão e absorção de água. Os resultados constatam que a substituição da areia por CBC foram satisfatórios visto que, quanto maior quantidade de CBC mais resistência foi apresentada

Effect of the gelatin extraction method from tilapia skin and its application as a coating

The objective of this study was to analyze gelatins extracted from tilapia (Oreochromis niloticus) skin and evaluate its effect as a coating on fish fillets of the same species. Four gelatin extractions from tilapia skins were prepared in acidic and alkaline conditions, followed by filtration and freeze drying. The samples were analyzed for moisture, lipids, ash, proteins, color parameters, viscosity, spectrophotometry and the coatings made with fish gelatin (FG) and commercial gelatin (CG) were sensorially tested. The protein content and the viscosity of the FG were influenced by the extraction method. The fillets coated with FG showed less moisture than those coated with CG. The sensorial acceptance of the fillets was not influenced by the use of the coatings. Therefore, the use of fish gelatin appears as a sustainable alternative to use tilapia skin after disposal in industrial processing

Trabalho de enfermagem no centro de atenção psicossocial: estresse e estratégias de coping

Doi: 10.5902/2179769214163 Objectives: to identify the feelings experienced at work in mental health; learn coping strategies reported by nursing professionals. Method: this is an exploratory-descriptive qualitative study conducted by semi-structured interviews with 12 nursing professionals of CAPS III, in Campina Grande-PB. The analysis was based on Bardin content technique, which resulted in the creation of two categories: Feelings and stress on mental health work; Coping strategies. Results: feelings of insecurity, frustration and emotional exhaustion acted as triggers of stress of professionals working at CAPS. Therefore, some strategies were mentioned as possibilities of alleviating stress, such as social support, music and listening spaces. Conclusions: there was the need for psychological support to nursing professionals, for facing stress factors in their daily lives, demanding a better-conducted strategic planning by managers and the interdisciplinary team working in these services.Objetivos: identificar los sentimientos experimentados en trabajo en salud mental; conocer estrategias de afrontamiento citadas por los profesionales de enfermería. Método: estudio cualitativo exploratorio-descriptivo, entrevistas semi-estructuradas con 12 enfermeros CAPSIII, en Campina Grande (PB, Brasil). El análisis se basó en la técnica de contenido de Bardin, creando dos categorías: sentimientos y el estrés laboral en el trabajo en salud mental; estrategias de afrontamiento. Resultados: sentimientos como inseguridad, frustración y agotamiento emocional actuaron como desencadenantes del estrés de los profesionales que trabajan en el CAPS. Por ello, algunas estrategias fueron mencionados como posibilidades de aliviar el estrés, como el apoyo social, la música y espacios de escucha. Conclusiones: se verificó la necesidad de apoyo psicológico a los profesionales de enfermería, que enfrentan factores de estrés en su vida cotidiana, exigiendo una mejor planificación estratégica dirigida por gerentes y el equipo interdisciplinar que trabaja en ellos.Doi: 10.5902/2179769214163Objetivo: identificar os motivos causadores de estresse e as possibilidades de enfrentamento que os profissionais de enfermagem encontram ao trabalhar com o portador de sofrimento psíquico. Método: trata-se de um estudo exploratório-descritivo de abordagem qualitativa realizado com 12 profissionais de enfermagem do CAPS III - Reviver. A análise dos dados ocorreu a partir da análise de conteúdo. O estudo foi submetido ao comitê de ética em pesquisa nº CAAE0115.0.000.405-10.Resultados: aponta-se fatores como o medo, tensão e esgotamento emocional como desencadeadores do estresse em profissionais que atuam em serviços de saúde mental. Para tanto, estratégias benéficas e maléficas foram citadas como estratégia de enfrentamento a exemplo da bebida alcoólica e musicoterapia. Conclusões: verificou-se a necessidade de apoio psicológico aos profissionais de enfermagem, por enfrentam fatores estressores em seu cotidiano, exigindo um planejamento estratégico melhor direcionado por parte dos gestores e equipe interdisciplinar que atuam nesses serviços

Presumed Normal Hemodynamic Values of the Arteries in the Final Third Period of Gestation in Bitches

Background: Doppler ultrasonography enables the investigation of vascular blood flow indexes in gestational assessment, being able to detect vascular resistances that can affect fetal and maternal circulation, such as cases of placental insufficiency, associated with fetal cerebral oxygenation deficit and fetal distress. The study aims to assume hemodynamically normal values in the final third of gestation in bitches, of the umbilical, uteroplacental, middle cerebral and internal carotid arteries, correlating the obtained Doppler velocimetric indexes, for the assessment of the feto-placental circulation, and prediction of fetal viability indexes, fetal centralization and probable date of delivery.Materials, Methods & Results: Thirty healthy bitches were examined in the final third of gestation (40-60 days). These were evaluated by Doppler ultrasonography at 2 times (T): T1: between 40-50 days; T2: between 51-60 of gestation. At each time point, the peak systolic velocities (PSV) and end-diastolic velocities (EDV) used to obtain the pulsatility (IP) and resistivity (IR) indexes of the umbilical, uteroplacental, middle cerebral and internal carotid arteries of fetuses were evaluated. Also, the systole/diastole (S/D) ratio of these vessels was evaluated. The data obtained were subjected to analysis of variance and Tukey test, using a P value equal to 5%. A significant difference was observed between velocities and Doppler velocimetric indexes between the 2 phases of the gestational final third in all studied vessels. There was an increase in the values of PSV and EDV and a decrease in the indexes, as the probable date of delivery approached. The analysis of the umbilical cord IR showed an increase from P1 to P2 (P < 0.05), while the IP decreased at the same time. For all studied variables there was a statistically significant difference (P < 0.05). In the uteroplacental artery, similarly to the umbilical artery, the PSV and EDV values showed an increase between P1 and P2, while the S/D ratio decreased up to 60 days of gestation (P2). The IR and IP of these vessels decreased during the study interval in pregnant bitches. The studied variables showed a statistically significant difference when analyzed comparatively between P1 and P2 (P < 0.05). As for the middle cerebral artery and internal carotid artery, the PSV and EDV values increased until the end of pregnancy. Likewise, the Doppler velocimetric values and the S/D ratio decreased until the end of pregnancy (P2).Discussion: The hemodynamic values obtained for the umbilical artery and uterine artery were significantly different between 40 and 50 days of gestation (P1) and 50 and 60 days of gestation (P2), with a decrease in vascular resistance and an increase in velocities. It can be related to a greater association of maternal-fetal blood perfusion, due to the increased demand for the development of the fetus. The Middle Cerebral Artery (MCA) also showed changes between P1 and P2, with an increase in PSV and EDV in the final third of pregnancy, and the S/D ratio was reduced, differing significantly between P1 and P2. The systolic (PSV) and diastolic (EDV) flow velocities of the internal carotid artery increased progressively, while the IR, IP and the S/D ratio decreased, between the evaluated periods (P1 and P2), providing greater flow in canine fetuses, maintaining normal heart rate, indicating positive fetal viability. Keywords: Doppler, gestational ultrasound, bitches, fetal circulation, umbilical artery, internal carotid, fetal middle cerebral artery

Lactobacillus paracasei CNCM I-5220-derived postbiotic protects from the leaky-gut

The maintenance of intestinal barrier function is essential for preventing different pathologies, such as the leaky gut syndrome (LGS), which is characterized by the passage of harmful agents, like bacteria, toxins, and viruses, into the bloodstream. Intestinal barrier integrity is controlled by several players, including the gut microbiota. Various molecules, called postbiotics, are released during the natural metabolic activity of the microbiota. Postbiotics can regulate host–microbe interactions, epithelial homeostasis, and have overall benefits for our health. In this work, we used in vitro and in vivo systems to demonstrate the role of Lactobacillus paracasei CNCM I-5220-derived postbiotic (LP-PBF) in preserving intestinal barrier integrity. We demonstrated in vitro that LP-PBF restored the morphology of tight junctions (TJs) that were altered upon Salmonella typhimurium exposure. In vivo, LP-PBF protected the gut vascular barrier and blocked S. typhimurium dissemination into the bloodstream. Interestingly, we found that LP-PBF interacts not only with the host cells, but also directly with S. typhimurium blocking its biofilm formation, partially due to the presence of biosurfactants. This study highlights that LP-PBF is beneficial in maintaining gut homeostasis due to the synergistic effect of its different components. These results suggest that LP-PBF could be utilized in managing several pathologies displaying an impaired intestinal barrier function

Data-driven optimization of search service composition for answering multi-domain queries

Answering multi-domain queries requires the combination of knowledge from various domains. Such queries are inadequately answered by general-purpose search engines, because domain- specific systems typically exhibit sophisticated knowledge about their own fields of expertise. Moreover, multi-domain queries typically require combining in the result domain knowledge possibly coming from multiple web resources, therefore conventional crawling and indexing techniques, based on individual pages, are not adequate. In this paper we present a conceptual framework for addressing the composition of search services for solving multi-domain queries. The approach consists in building an infrastructure for search service composition that leaves within each search system the responsibility of maintaining and improving its domain knowledge, and whose main challenge is to provide the “glue” between them; such glue is expressed in the format of joins upon search service results, and for this feature we regard our approach as “data-driven”. We present an overall architecture, and the work that has been done so far in the development of some of the main modules.publishe