Evidence for Distinct Components of the Galactic Stellar Halo from 838 RR Lyrae Stars Discovered in the LONEOS-I Survey

We present 838 ab-type RR Lyrae stars from the Lowell Observatory Near Earth Objects Survey Phase I (LONEOS-I). These objects cover 1430 deg^2 and span distances ranging from 3-30 kpc from the Galactic Center. Object selection is based on phased, photometric data with 28-50 epochs. We use this large sample to explore the bulk properties of the stellar halo, including the spatial distribution. The period-amplitude distribution of this sample shows that the majority of these RR Lyrae stars resemble Oosterhoff type I, but there is a significant fraction (26 %) which have longer periods and appear to be Oosterhoff type II. We find that the radial distributions of these two populations have significantly different profiles (rho_{OoI} ~ R^(-2.26 +- 0.07) and rho_{OoII} ~ R^(-2.88 +- 0.11). This suggests that the stellar halo was formed by at least two distinct accretion processes and supports dual-halo models.Comment: 18 pages, 28 figures, apjemulated, minor corrections and clarifications. Accepted to ApJ on Jan 21, 200

Single-strand selective monofunctional uracil-DNA glycosylase (SMUG1) deficiency is linked to aggressive breast cancer and predicts response to adjuvant therapy

Uracil in DNA is an important cause of mutagenesis. SMUG1 is a uracil DNA glycosylase that removes uracil through base excision repair. SMUG1 also processes radiation induced oxidative base damage as well as 5-fluorouracil incorporated into DNA during chemotherapy. We investigated SMUG1 mRNA expression in 249 primary breast cancers. SMUG1 protein expression was investigated in 1165 breast tumours randomised into two cohorts [training set (n=583) and test set (n=582)]. SMUG1 and chemotherapy response was also investigated in a series of 315 ER negative tumours (n=315). For mechanistic insights, SMUG1 was correlated to biomarkers of aggressive phenotype, DNA repair, cell cycle and apoptosis. Low SMUG1 mRNA expression was associated with adverse disease specific survival (p=0.008) and disease free survival (p=0.008). Low SMUG1 protein expression (25%) was associated with high histological grade (p<0.0001), high mitotic index (p<0.0001), pleomorphism (p<0.0001), glandular de-differentiation (p=0.0001), absence of hormonal receptors (ER-/PgR-/AR) (p<0.0001), presence of basal-like (p<0.0001) and triple negative phenotypes (p<0.0001). Low SMUG1 protein expression was associated with loss of BRCA1 (p<0.0001), ATM (p<0.0001) and XRCC1 (p<0.0001). Low p27 (p<0.0001), low p21 (p=0.023), mutant p53 (p=0.037), low MDM2 (p<0.0001), low MDM4 (p=0.004), low Bcl-2 (p=0.001), low Bax (p=0.003) and high MIB1 (p<0.0001) were likely in low SMUG1 tumours. Low SMUG1 protein expression was associated with poor prognosis in univariate (p<0.001) and multivariate analysis (p<0.01). In ER+ cohort that received adjuvant endocrine therapy, low SMUG1 protein expression remains associated with poor survival (p<0.01). In ER- cohort that received adjuvant chemotherapy, low SMUG1 protein expression is associated with improved survival (p=0.043). Our study suggests that low SMUG1 expression may correlate to adverse clinicopathological features and predict response to adjuvant therapy in breast cancer

Heating of near-Earth objects and meteoroids due to close approaches to the Sun

It is known that near-Earth objects (NEOs) during their orbital evolution may often undergo close approaches to the Sun. Indeed it is estimated that up to ~70% of them end their orbital evolution colliding with the Sun. Starting from the present orbital properties, it is possible to compute the most likely past evolution for every NEO, and to trace its distance from the Sun. We find that a large fraction of the population may have experienced in the past frequent close approaches, and thus, as a consequence, a considerable Sun-driven heating, not trivially correlated to the present orbits. The detailed dynamical behaviour, the rotational and the thermal properties of NEOs determine the exact amount of the resulting heating due to the Sun. In the present paper we discuss the general features of the process, providing estimates of the surface temperature reached by NEOs during their evolution. Moreover, we investigate the effects of this process on meteor-size bodies, analyzing possible differences with the NEO population. We also discuss some possible effects of the heating which can be observed through remote sensing by ground-based surveys or space missions.Comment: 8 pages, 5 figures, accepted by MNRA

Determination of the Nature of the Tetragonal to Orthorhombic Phase Transition in SrFe_2As_2 by Measurement of the Local Order Parameter

SrFe2As2 is the end-member for a series of iron-pnictide superconductors and has a tetragonal-to-orthorhombic phase transition near 200 K. Previous macroscopic measurements to determine the nature of the transition gave seemingly inconsistent results so we use electron microscopy to monitor the local order parameter showing that the transformation is first order and that the orthorhombic phase grows as needle domains. This suggests the transition occurs via the passage of transformation dislocations, explaining the apparent inconsistencies. This mechanism may be common to similar transitions.Comment: 4 pages, 4 figures submitted to Physical Review Letters. Supplementary information can be found at http://cook.msm.cam.ac.uk/~supp_info/ An extra sentence in the second last paragraph and reference 16 has been adde

Spin density wave induced disordering of the vortex lattice in superconducting La2−x_{2-x}Srx_xCuO4_4

We use small angle neutron scattering to study the superconducting vortex lattice in La$_{2-x}$Sr$_x$CuO$_4$ as a function of doping and magnetic field. We show that near optimally doping the vortex lattice coordination and the superconducting coherence length $\xi$ are controlled by a van-Hove singularity crossing the Fermi level near the Brillouin zone boundary. The vortex lattice properties change dramatically as a spin-density-wave instability is approached upon underdoping. The Bragg glass paradigm provides a good description of this regime and suggests that SDW order acts as a novel source of disorder on the vortex lattice.Comment: Accepted in Phys. Rev.

(1173) Anchises - Thermophysical and Dynamical Studies of a Dynamically Unstable Jovian Trojan

We have performed detailed thermophysical and dynamical modelling of Jovian Trojan (1173) Anchises. Our results reveal a most unusual object. By examining observational data taken by IRAS, Akari and WISE between 11.5 and 60 microns, along with variations in its optical lightcurve, we find Anchises is most likely an elongated body, with an axes-ratio of ~1.4. This yields calculated best-fit dimensions of 170x121x121km (an equivalent diameter of 136+18/-11km). We find the observations are best fit by Anchises having a retrograde sense of rotation, and an unusually high thermal inertia (25 to 100 Jm-2s-0.5K-1). The geometric albedo is found to be 0.027 (+0.006/-0.007). Anchises therefore has one of the highest published thermal inertias of any object larger than 100km in diameter, at such large heliocentric distances, and is one of the lowest albedo objects ever observed. More observations are needed to see if there is a link between the very shallow phase curve, with almost no opposition effect, and the derived thermal properties for this large Trojan asteroid. Our dynamical investigation of Anchises' orbit has revealed it to be dynamically unstable on timescales of hundreds of Myr, similar to the unstable Neptunian Trojans 2001 QR322 and 2008 LC18. Unlike those objects, we find that Anchises' dynamical stability is not a function of its initial orbital elements, the result of the exceptional precision with which its orbit is known. This is the first time that a Jovian Trojan has been shown to be dynamically unstable, and adds weight to the idea that planetary Trojans represent a significant ongoing contribution to the Centaur population, the parents of the short-period comets. The observed instability does not rule out a primordial origin for Anchises, but when taken in concert with the result of our thermophysical analysis, suggest that it would be a fascinating target for future study.Comment: 5 figures, 3 tables, accepted for publication in Monthly Notices of the Royal Astronomical Societ

The diameter of 88 Thisbe from its occultation of SAO 187124

The 7 October, 1981 occultation of SAO 187124 by 88 Thisbe was observed at twelve sites. The occultation observations, together with information about the asteroid's light curve, gives a mean diameter for Thisbe of 232 + or - 10 km. This value is 10 percent larger than the previously published radiometric diameter of Thisbe

WISE/NEOWISE Observations of the Jovian Trojans: Preliminary Results

We present the preliminary analysis of over 1739 known and 349 candidate Jovian Trojans observed by the NEOWISE component of the Wide-field Infrared Survey Explorer (WISE). With this survey the available diameters, albedos and beaming parameters for the Jovian Trojans have been increased by more than an order of magnitude compared to previous surveys. We find that the Jovian Trojan population is very homogenous for sizes larger than $\sim10$km (close to the detection limit of WISE for these objects). The observed sample consists almost exclusively of low albedo objects, having a mean albedo value of $0.07\pm0.03$. The beaming parameter was also derived for a large fraction of the observed sample, and it is also very homogenous with an observed mean value of $0.88\pm0.13$. Preliminary debiasing of the survey shows our observed sample is consistent with the leading cloud containing more objects than the trailing cloud. We estimate the fraction to be N(leading)/N(trailing) $\sim 1.4 \pm 0.2$, lower than the $1.6 \pm 0.1$ value derived by others.Comment: Accepted for publication in Astrophysical Journal. Electronic table will be available at the publishers websit

Ultraviolet and visible photometry of asteroid (21) Lutetia using the Hubble Space Telescope

The asteroid (21) Lutetia is the target of a planned close encounter by the Rosetta spacecraft in July 2010. To prepare for that flyby, Lutetia has been extensively observed by a variety of astronomical facilities. We used the Hubble Space Telescope (HST) to determine the albedo of Lutetia over a wide wavelength range, extending from ~150 nm to ~700 nm. Using data from a variety of HST filters and a ground-based visible light spectrum, we employed synthetic photometry techniques to derive absolute fluxes for Lutetia. New results from ground-based measurements of Lutetia's size and shape were used to convert the absolute fluxes into albedos. We present our best model for the spectral energy distribution of Lutetia over the wavelength range 120-800 nm. There appears to be a steep drop in the albedo (by a factor of ~2) for wavelengths shorter than ~300 nm. Nevertheless, the far ultraviolet albedo of Lutetia (~10%) is considerably larger than that of typical C-chondrite material (~4%). The geometric albedo at 550 nm is 16.5 +/- 1%. Lutetia's reflectivity is not consistent with a metal-dominated surface at infrared or radar wavelengths, and its albedo at all wavelengths (UV-visibile-IR-radar) is larger than observed for typical primitive, chondritic material. We derive a relatively high FUV albedo of ~10%, a result that will be tested by observations with the Alice spectrograph during the Rosetta flyby of Lutetia in July 2010.Comment: 14 pages, 2 tables, 8 figure