9 research outputs found

    Métastases cutanées révélant un adénocarcinome bronchique

    Get PDF
    Nous rapportons le cas d’un cancer bronchique rĂ©vĂ©lĂ© par des nodules cutanĂ©s mĂ©tastatiques du cuir chevelu. Ce mode de dĂ©couverte assez frĂ©quent est souvent associĂ© Ă  un mauvais pronostic. Cette observation souligne l’intĂ©rĂȘt de rechercher un cancer primitif pulmonaire en cas de localisation secondaire cutanĂ©e.English abstractWe report the case of bronchial carcinoma revealed by metastatic skin nodules on the scalp. This fairly common mode of discovery is often associated with poor prognosis. This study aims to underline the importance of directing the search for a primary lung cancer in cases of secondary skin involvement.Key words: Cutaneous metastases, bronchial adenocarcinoma, excisional biops

    Textilome abdominal: Ă  propos d'un cas

    Get PDF
    Le textilome est une complication postopĂ©ratoire trĂšs rare mais bien connue. Il peut s'agir d'un corps Ă©tranger composĂ© de compresse(s) ou champ(s) chirurgicaux laissĂ©s au niveau d'un foyer opĂ©ratoire. La dĂ©couverte du textilome abdominale est gĂ©nĂ©ralement tardive. L'anamnĂšse est donc essentielle pour diagnostic vu que la clinique n'est pas concluante. La clinique associe des troubles chroniques du transit Ă  des syndromes sub-occlusifs, le clichĂ© d'abdomen sans prĂ©paration est peu contributif. L’échographie est fiable. La tomodensitomĂ©trie permet un diagnostic topographique prĂ©cis. Certaines Ă©quipes proposent des explorations par IRM. Nous rapportons un cas de textilome intra abdominale, chez une patiente opĂ©rĂ©e 6 mois auparavant d'un fibrome utĂ©rin

    Bee venom: a case of effectiveness on skin varicosities veins with review of its dermatological benefits

    No full text
    Bee venom is a very rich and varied biochemical complex, which explains the multitude of its physiological effects as well as its medical indications. In dermatology, apart from psoriasis, few studies have been conducted concerning its interest and effectiveness; however the preliminary results remain so promising and encouraging. We present a clinical case illustrating the efficacy of bee venom in cutaneous varicosities, with a review of the literature of its main dermatological indications

    Hepatic Metastasis Revealing a Melanoma of the Penis: Case Report

    No full text
    Melanoma of the penis is a rare tumor with a poor prognosis. We report the case of a 73-year-old patient with no significant medical history, admitted for deterioration of the general condition and bilateral inguinal lymph nodes. An abdominal ultrasound and thoraco-abdomino-pelvic CT (computed tomography) scan revealed metastatic liver nodules, the tumoral nature of which was confirmed by an anatomopathological examination. Further clinical examination revealed papular and ulcerated lesions of the penis located at the urethral meatus and glans penis. These lesions were biopsied and histologically assessed as melanoma. The contribution of imaging in penile tumors is generally not useful for diagnosis as clinical examination is key. However, it has its place in the assessment of locoregional and distant extension. In our case, it was the distant lesions that helped orient the diagnosis. The patient underwent immunotherapical treatment and is still alive 19 months after the diagnosis

    Le condylome acuminĂ© isolĂ© de la cavitĂ© buccale : Ă  propos d’un cas clinique

    No full text
    Introduction : Le condylome acuminĂ© est une tumeur Ă©pithĂ©liale bĂ©nigne classĂ©e parmi les infections sexuellement transmissibles. Les virus responsables des condylomes sont Ă  90 % les papillomavirus muqueux de type 6 et 11 rĂ©putĂ©s Ă  bas risque de cancĂ©risation. Le but de ce travail est de rappeler les aspects cliniques, histologiques et thĂ©rapeutiques du condylome acuminĂ© de la cavitĂ© buccale et de mettre la lumiĂšre sur ses voies de transmission non sexuelle. Observation : Il s’agissait d’un patient ĂągĂ© de trente ans, sans notion de pratique sexuelle bucco-gĂ©nitale, qui prĂ©sentait des lĂ©sions blanchĂątres millimĂ©triques au niveau du palais et de la commissure labiale gauche Ă©voluant depuis un an. L’exĂ©rĂšse des deux lĂ©sions palatines avait Ă©tĂ© rĂ©alisĂ©e ainsi qu’une biopsie des lĂ©sions de la commissure labiale gauche complĂ©tĂ©e par une Ă©lectrocoagulation. L’examen histologique confirmait le diagnostic de condylome. Le suivi postopĂ©ratoire ne montrait aucune rĂ©cidive aprĂšs dix mois de surveillance. Discussion : Les condylomes buccaux sont exceptionnels et sont souvent secondaires Ă  une contamination par contact sexuel direct. Cependant d’autres voies de transmission non liĂ©es aux relations sexuelles sont dĂ©crites. Le diagnostic est suspectĂ© cliniquement et confirmĂ© par l’étude histologique. Un traitement radical basĂ© sur l’exĂ©rĂšse chirurgicale avec excision ou Ă©lectrocoagulation s’impose vu le caractĂšre hautement contagieux des lĂ©sions. Conclusion : Le condylome acuminĂ© est rarement de localisation buccale. Son diagnostic procĂšde conjointement d’un entretien mĂ©dical soigneux et de l’examen histologique

    Mucocele apendicular: a propĂłsito de un caso

    No full text
    Resumen: El mucocele apendicular es una entidad patológica rara, pero potencialmente peligrosa, se presenta en diferentes formas clínicas. Presentamos el caso de un paciente de 47 años, sin antecedentes particulares, que consulta por dolor crónico en fosa ilíaca derecha y cuya tomografía computarizada abdomino-pélvica muestra una masa quística del apéndice que evoca un mucocele apendicular. El paciente se sometió a una apendicectomía. El anålisis histológico de este confirmó el diagnóstico de mucocele apendicular sin células malignas. El seguimiento postoperatorio fue sencillo. Abstract: Appendiceal mucocele is a rare pathological entity, but potentially dangerous, it presents in different clinical forms. We present the case of a 47-year-old patient, with no particular history, who consulted for chronic pain in the right iliac fossa and whose abdominal-pelvic computed tomography showed a cystic mass in the appendix that evokes an appendiceal mucocele. The patient underwent an appendectomy. Histological analysis of this confirmed the diagnosis of appendiceal mucocele without malignant cells. Postoperative follow-up was easy

    Prevalence of resistance to integrase strand-transfer inhibitors (INSTIs) among untreated HIV-1 infected patients in Morocco

    No full text
    Abstract Objective The integrase strand-transfer inhibitors (INSTIs) are an important class in the arsenal of antiretroviral drugs designed to block the integration of HIV-1 cDNA into the host DNA through the inhibition of DNA strand transfer. In this study for the first time in Morocco, the complete HIV-1 integrase gene was analysed from newly diagnosed patients to evaluate the prevalence of natural polymorphisms and INSTIs resistance-associated mutations in the integrase gene. Results The 864pb IN coding region was successfully sequenced from plasma sample for 77 among 80 antiretroviral naĂŻve patients. The sequences were interpreted for drug resistance according to the Stanford algorithm. Sixty samples were HIV-1 subtype B (78%), fourteen CRF02_AG (18%), two subtype C and one subtype A. Overall 81 of 288 (28%) amino acid IN positions presented at least one polymorphism each. We found 18 (36.73%), 42 (25.76%) and 21 (27.27%) of polymorphic residues assigned to the N-Terminal Domain, Catalytic Core Domaine and the C-Terminal Domain positions respectively. Primary INSTIs resistance mutation were absent, however secondary mutations L74IM, T97A were detected in four samples (5.2%). These results demonstrate that untreated HIV-1 infected Moroccans will be susceptible to INSTIs

    MOESM1 of Prevalence of resistance to integrase strand-transfer inhibitors (INSTIs) among untreated HIV-1 infected patients in Morocco

    No full text
    Additional file 1. Distribution of IN mutations in subtypes B and non-B in therapy-naĂƻve patients. Secondary and additional mutations screened in 17 positions (V72I, T112I, S119PRTG, T124A, T125K, A128T, Q146K, M154I, K156N, V165I, V201I, I203M, T206S, S230N, D232N, V249I and C280Y) using the Stanford HIV Drug Resistance Program (Version September 23, 2016), all mutations identified in this study are likely natural polymorphisms

    Side-effects of henna and semi-permanent ‘black henna’ tattoos: a full review

    No full text
    corecore