From Self-Legislation to Self-Determination: Democracy and the New Circumstances of Politics

It is a distinctive feature of recent political order that democracy is no longer confined to the nation state. Democracy is now applied in complex, pluralist, and globalized settings. These settings are characterized by extensive, multiple and overlapping constituencies. Here we might think of the significance of these developments for self-determining individuals, who are able to influence those interdependencies that are problematic, such as domination and other ways in which self-determination can be undermined. Democracy serves to delegate power to higher and more complex units of decision-making organized around self-determination. Some of these units have generative properties, in the sense that they make it possible for deliberation to occur, without undermining self-determination. Contestability is part of self-determination, where this goes along with forums with the purpose of determining binding norms. In this way, forms of politics emerge based on the rights and powers of self-determining democratic citizens

The Coming of Age of Deliberative Democracy

Reviso tres maneras diferentes como los ideales de la democracia deliberativa han cambiado a la luz de las preocupaciones prácticas sobre su viabilidad, es decir, haciendo cada vez más importante el problema de cómo este ideal puede acercarse a sociedades caracterizadas por profundos desacuerdos, problemas sociales de enorme complejidad e instrumentos inoperantes en sus instituciones existentes. En primer lugar, las teorías de la democracia deliberativa enfatizan el proceso mismo de la deliberación, y no sus condiciones y procedimientos ideales y contrafácticos. En segundo lugar, los demócratas deliberativos se interesan cada vez más en los problemas de la institucionalización, en hacer del voto, la regla de mayorías, la representación, los tribunales y el derecho constitucional, instituciones más deliberativas, en pro de una mayor democracia directa. En tercer lugar, los deliberativistas se ocupan de examinar y comparar los diferentes escenarios y procedimientos de la deliberación, señalando problemas empíricos y obstáculos que no siempre pueden anticiparse al recurrir únicamente a argumentos conceptuales.I will be reviewing three different ways in which the ideals of deliberative democracy have changed in light of practical concerns of feasibility, that is, by making the problem of how this ideal would be approximated increasingly central in societies characterized by deep disagreements, social problems of enormous complexity and also consider the blunt instruments of available institutions. First, theories of deliberative democracy have come to emphasize the process of deliberation itself, rather than its ideal and counterfactual conditions and procedures. Second, deliberative democrats have become increasingly interested in the problems of institutionalization, of making institutions such as voting and majority rule, representation, courts and constitutional law more deliberative rather than rejecting them for more direct democracy. Third, these aforementioned democrats are concerned with examining and comparing different settings and procedures of deliberation, pointing out empirical problems and obstacles that cannot always be anticipated by conceptual argument alone

Development of in vitro methods to model the impact of vaginal lactobacilli on Staphylococcus aureus biofilm formation on menstrual cups as well as validation of recommended cleaning directions

IntroductionMenstrual cups (MC) are a reusable feminine hygiene product. A recent publication suggested that Staphylococcus aureus (S. aureus) biofilms can form on MCs which may lead to increased risk of menstrual Toxic Shock Syndrome (mTSS). Additionally, there is concern that buildup of residual menses may contribute to microbial growth and biofilm formation further increasing mTSS risk. Quantitative and qualitative analysis of in vitro tests were utilized to determine if S. aureus biofilm could form on MC in the presence of the keystone species Lactobacillus after 12 h of incubation. The methodology was based on a modification of an anaerobic in vitro method that harnesses the keystone species hypothesis by including a representative of vaginal lactic acid bacteria.MethodsMCs were incubated anaerobically for 12 h in Vaginal Defined Media (VDM) with the two morphologically distinct bacteria, Lactobacillus gasseri (L. gasseri) and S. aureus. Colony Forming Units (CFU) for each organism from the VDM broth and sonicated MC were estimated. In addition, a separate experiment was conducted where S. aureus was grown for 12 h in the absence of L. gasseri. Qualitative analysis for biofilm formation utilized micro-CT (µ-CT) and cryogenic scanning electron microscopy (Cryo-SEM).ResultsSamples collected from the media control had expected growth of both organisms after 12 h of incubation. Samples collected from VDM broth were similar to media control at the end of the 12-h study. Total S. aureus cell density on MC following sonication/rinsing was minimal. Results when using a monoculture of S. aureus demonstrated that there was a significant growth of the organism in the media control and broth as well as the sonicated cups indicating that the presence of L. gasseri was important for controlling growth and adherence of S. aureus. Few rod-shaped bacteria (L. gasseri) and cocci (S. aureus) could be identified on the MCs when grown in a dual species culture inoculum and no biofilm was noted via µ-CT and cryo-SEM. Additionally, efforts to model and understand the validity of the current labeled recommendations for MC cleaning in-between uses are supported.DiscussionThe data support continued safe use of the Tampax® cup when used and maintained as recommended

The last animal: cosmopolitanism in The Last Man

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Impacts of urban drainage systems on stormwater hydrology: Rocky Branch Watershed, Columbia, South Carolina

[[abstract]]Abstract Increases in impervious surfaces and land-use changes associated with urbanization have long been the focus of urban hydrological research. However, studies and calculations that consider impervious surfaces alone do not encompass all factors that influence urban hydrologic response, as alternative urban structures may have a substantial effect on stormflow. This study examines several descriptors to improve estimations of hydrologic impacts of urbanization in small watersheds. Configurations of drainage densities that include storm sewers were computed for the highly urbanized Rocky Branch Watershed. Storm sewer configurations resulted in an approximate tripling of the drainage density. In addition, rainfall and stormflow data were analyzed to compare the hydrologic response of two subcatchments with varying percentages of impervious areas and drainage densities. The subcatchment with a higher percentage of impervious area produced significantly (p < .01) higher runoff volumes with an average runoff coefficient of 0.446, while the subcatchment with higher storm sewer densities displayed significantly shorter lag times of 9 min. In this case, the percentage of impervious area increased the volume of runoff but, storm sewer densities accelerated hydrologic responses, suggesting that hydrologically relevant metrics should be considered to accurate assess flood risk alternatives.[[sponsorship]]McCormick Taylor, Inc., Grant/Award Number: 13540‐16‐41674; Office of the Vice President for Research, University of South Carolina, Grant/Award Number: 13540‐16‐41303[[notice]]補正完

New molecular methods to assess biodiversity. Potentials and pitfalls of DNA metabarcoding: a workshop report

This report presents the outcome of the joint work of PhD students and senior researchers working with DNA-based biodiversity assessment approaches with the goal to facilitate others the access to definitions and explanations about novel DNA-based methods. The work was performed during a PhD course (SLU PNS0169) at the Swedish University of Agricultural Sciences (SLU) in Uppsala, Sweden. The course was co-organized by the EU COST research network DNAqua-Net and the SLU Research Schools Focus on Soils and Water (FoSW) and Ecology - basics and applications. DNAqua-Net (COST Action CA15219, 2016-2020) is a network connecting researchers, water managers, politicians and other stakeholders with the aim to develop new genetic tools for bioassessment of aquatic ecosystems in Europe and beyond. The PhD course offered a comprehensive overview of the paradigm shift from traditional morphology-based species identification to novel identification approaches based on molecular markers. We covered the use of molecular tools in both basic research and applied use with a focus on aquatic ecosystem assessment, from species collection to the use of diversity in environmental legislation. The focus of the course was on DNA (meta)barcoding and aquatic organisms. The knowledge gained was shared with the general public by creating Wikipedia pages and through this collaborative Open Access publication, co-authored by all course participants

Deliberative and epistemic approaches to democracy

Deliberative and epistemic approaches to democracy are two important dimensions of contemporary democratic theory. This chapter studies these dimensions in the emerging ecosystem of civic and political participation tools, and appraises their collective value in a new distinct concept: linked democracy. Linked democracy is the distributed, technology-supported collective decision-making process, where data, information and knowledge are connected and shared by citizens online. Innovation and learning are two key elements of Athenian democracies which can be facilitated by the new digital technologies, and a cross-disciplinary research involving computational scientists and democratic theorists can lead to new theoretical insights of democracy

Intracranial and subcortical volumes in adolescents with early‐onset psychosis: A multisite mega‐analysis from the ENIGMA consortium

Early‐onset psychosis disorders are serious mental disorders arising before the age of 18 years. Here, we investigate the largest neuroimaging dataset, to date, of patients with early‐onset psychosis and healthy controls for differences in intracranial and subcortical brain volumes. The sample included 263 patients with early‐onset psychosis (mean age: 16.4 ± 1.4 years, mean illness duration: 1.5 ± 1.4 years, 39.2% female) and 359 healthy controls (mean age: 15.9 ± 1.7 years, 45.4% female) with magnetic resonance imaging data, pooled from 11 clinical cohorts. Patients were diagnosed with early‐onset schizophrenia (n = 183), affective psychosis (n = 39), or other psychotic disorders (n = 41). We used linear mixed‐effects models to investigate differences in intracranial and subcortical volumes across the patient sample, diagnostic subgroup and antipsychotic medication, relative to controls. We observed significantly lower intracranial (Cohen's d = −0.39) and hippocampal (d = −0.25) volumes, and higher caudate (d = 0.25) and pallidum (d = 0.24) volumes in patients relative to controls. Intracranial volume was lower in both early‐onset schizophrenia (d = −0.34) and affective psychosis (d = −0.42), and early‐onset schizophrenia showed lower hippocampal (d = −0.24) and higher pallidum (d = 0.29) volumes. Patients who were currently treated with antipsychotic medication (n = 193) had significantly lower intracranial volume (d = −0.42). The findings demonstrate a similar pattern of brain alterations in early‐onset psychosis as previously reported in adult psychosis, but with notably low intracranial volume. The low intracranial volume suggests disrupted neurodevelopment in adolescent early‐onset psychosis