Warum die Direkte Demokratie den Anstieg der Staatsquote in der Schweiz nicht verhindern konnte

Diese Arbeit dokumentiert und analysiert den Anstieg der Staatsausgaben und der Defizite in den 90er Jahren. Die unmittelbaren Ursachen des Anstiegs sind bekannt: höhere Ausgaben für die Altersvorsorge und andere Bereiche der sozialen Sicherheit sowie Kostensteigerungen im Gesundheitswesen machen den Löwenanteil des Anstiegs aus. Polit-ökonomisch sind die Ursachen dagegen nicht klar. Nach den Resultaten der wissenschaftlichen Literatur sollte die direkte Demokratie bremsend auf das Wachstum von Ausgaben und Defiziten wirken. Wir überprüfen die empirische Evidenz und finden, dass Unterschiede im Ausmass der direkten Demokratie in den Kantonen keinerlei Einfluss auf das Wachstum der kantonalen Staatsausgaben oder auf die Staatsdefizite hatten. Wir untersuchen deshalb auch die Determinanten des Niveaus der kantonalen Ausgaben und finden, dass der Einfluss der direkten Demokratie wenig robust ist

Food For Thought: Nutrition Education and Nutrient Delivery at Two Local Elementary Schools

I designed a 20 minute powerpoint presentation and delivered it to healthcare providers in the area. - Discussed the growing problem of obesity, and new federal regulations designed to curb it - Summarized data gathered in interviews at both schools - Compared schools to each other - Suggested changes that each school could make in the future - Offered suggestions for changes in office practices and office collaboration with schools, for PCP\u27s in the areahttps://scholarworks.uvm.edu/fmclerk/1009/thumbnail.jp

Efficient minimization of multipole electrostatic potentials in torsion space

The development of models of macromolecular electrostatics capable of delivering improved fidelity to quantum mechanical calculations is an active field of research in computational chemistry. Most molecular force field development takes place in the context of models with full Cartesian coordinate degrees of freedom. Nevertheless, a number of macromolecular modeling programs use a reduced set of conformational variables limited to rotatable bonds. Efficient algorithms for minimizing the energies of macromolecular systems with torsional degrees of freedom have been developed with the assumption that all atom-atom interaction potentials are isotropic. We describe novel modifications to address the anisotropy of higher order multipole terms while retaining the efficiency of these approaches. In addition, we present a treatment for obtaining derivatives of atom-centered tensors with respect to torsional degrees of freedom. We apply these results to enable minimization of the Amoeba multipole electrostatics potential in a system with torsional degrees of freedom, and validate the correctness of the gradients by comparison to finite difference approximations. In the interest of enabling a complete model of electrostatics with implicit treatment of solvent-mediated effects, we also derive expressions for the derivative of solvent accessible surface area with respect to torsional degrees of freedom

Metformin, Sulfonylureas, or Other Antidiabetes Drugs and the Risk of Lactic Acidosis or Hypoglycemia

OBJECTIVE: Lactic acidosis has been associated with use of metformin. Hypoglycemia is a major concern using sulfonylureas. The aim of this study was to compare the risk of lactic acidosis and hypoglycemia among patients with type 2 diabetes using oral antidiabetes drugs. RESEARCH DESIGN AND METHODS: This study is a nested case-control analysis using the U.K.-based General Practice Research Database to identify patients with type 2 diabetes who used oral antidiabetes drugs. Within the study population, all incident cases of lactic acidosis and hypoglycemia were identified, and hypoglycemia case subjects were matched to up to four control patients based on age, sex, practice, and calendar time. RESULTS: Among the study population of 50,048 type 2 diabetic subjects, six cases of lactic acidosis during current use of oral antidiabetes drugs were identified, yielding a crude incidence rate of 3.3 cases per 100,000 person-years among metformin users and 4.8 cases per 100,000 person-years among users of sulfonylureas. Relevant comorbidities known as risk factors for lactic acidosis could be identified in all case subjects. A total of 2,025 case subjects with hypoglycemia and 7,278 matched control subjects were identified. Use of sulfonylureas was associated with a materially elevated risk of hypoglycemia. The adjusted odds ratio for current use of sulfonylureas was 2.79 (95% CI 2.23–3.50) compared with current metformin use. CONCLUSIONS: Lactic acidosis during current use of oral antidiabetes drugs was very rare and was associated with concurrent comorbidity. Hypoglycemic episodes were substantially more common among sulfonylurea users than among users of metformin.Merck SA, Lyon, Franc

La crisis y la pedagogía económica

La crisis y la pedagogía económic

Die Determinanten des Wirtschaftswachstums in den OECD Ländern

Diese Arbeit untersucht die Determinanten des Wirtschaftswachstums in OECD-Ländern für die Periode von 1960 bis 2000. Die geschätzten Wachstumsregressionen ergeben dabei mit überraschender Deutlichkeit, dass das Wachstum der Staatsquote eine wichtige negative und die grössere Offenheit eine wichtige positive Rolle spielten. Wir verwenden die geschätzte Gleichung zu einer Analyse des Wachstums der Schweiz und einiger anderer Länder.Für die Schweiz ist dabei eine vollständige Erklärung des Einbruchs der 90er Jahre nicht möglich. Allgemein zeigt sich, dass extreme Veränderungen - wie diejenige von Irland auf der positiven und der Schweiz auf der negativen Seite - von den Regressionen nur teilweise erklärt werden können

Double Λ\Lambda Hypernuclei and the Nuclear Medium Effective ΛΛ\Lambda\Lambda Interaction

We fit the $^1 S_0 \Lambda\Lambda$ interaction in the nuclear medium to the masses of the experimentally known double-$\Lambda$ hypernuclei: $^{\phantom{6}6}_{\Lambda\Lambda}$He, $^{10}_{\Lambda\Lambda}$Be and $^{13}_{\Lambda\Lambda}$B. We derive this effective interaction from OBE J\"ulich $\Lambda\Lambda$-type potentials and using both Hartree-Fock and variational approaches. We find that the inclusion of $\Lambda\Lambda$ correlations in the variational scheme leads to significant differences and a better understanding of the dynamical features of the system. We investigate the sensitivity of the binding energies and the mesonic decay widths of the above double-$\Lambda$ hypernuclei to the $\omega \Lambda\Lambda$ coupling and the form factor at the $\sigma \Lambda\Lambda$ vertex. We also use this effective interaction to predict binding energies and pionic decay widths of heavier double-$\Lambda$ hypernuclei, not discovered yet. Finally, we discard the existence of $^1 S_0$ $\Lambda\Lambda$ bound states provided the $\Lambda\Lambda-\Xi N$ coupling can be neglected.Comment: 49 pages, LaTeX + 8 ps-figure file

Microscopic calculations of Λ single-particle energies

A binding energy data for total baryon number A ≤ 208 and for Λ angular momenta ℓΛ ≤ 3 are analyzed in terms of phenomenological (but generally consistent with meson-exchange) ΛN and ΛNN potentials. The Fermi hypernetted chain technique is used to calculate the expectation values for the Λ binding to nuclear matter. Accurate effective ΛN and ΛNN potentials are obtained which are folded with the core-nucleus nucleon densities to calculate the Λ single-particle potential UΛ (r). We use a dispersive ANN potential but also include an explicit ρ dependence to allow for reduced repulsion in the surface, and the best fits have a large ρ dependence giving consistency with the variational Monte Carlo calculations for 5ΛHe. The exchange fraction of the ΛN space-exchange potential is found to be 0.2-0.3 corresponding to m*Λ ≃ (0.74 - 0.82)mΛ. Charge-symmetry breaking is found to be significant for heavy hypernuclei with a large neutron excess, with a strength consistent with that obtained from the A = 4 hypernuclei

Mycobacterium avium resists exposure to the acidic conditions of the stomach

Organisms of the Mycobacterium avium complex are common pathogens in immunosuppressed patients such as individuals with AIDS. There is evidence that in AIDS patients, the main route for M. avium infection is the gastrointestinal tract. The stomach is a formidable barrier to pathogens and the ability to resist exposure to pH lower than 3 has been shown to be a virulence determinant of enteric pathogens. Incubation of three clinical isolates of M. avium under acidic pH revealed resistance of M. avium grown both to the exponential and stationary phase at pH 2.2 for 2 h. Inhibition of protein synthesis had no effect on the acid tolerance. When the duration of the incubation at pH 2.2 was extended to 24 h, bacteria grown to the stationary phase had a significantly greater tolerance to acid than exponential phase bacteria. M. avium incubated with acid in the presence of water was significantly more resistant to pH 2.2 than M. avium in the presence of buffer. Pre-adaptation in water prior to exposure to acidic conditions was also associated with increased resistance to pH 2.2. Isoosmolarity of Hank's balanced salt solution appears to be responsible for the impaired resistance to acid between 2 and 24 h of incubation. These findings indicate that M. avium is naturally tolerant to pH<3 and that pre-adaptation under conditions similar to the conditions where M. avium is found in the environment results in increased acid resistanc