Explicating sex differences in marketing managers\u27 egoist versus utilitarian ethical orientations: The effects of the enactment of agentic versus communal social roles

This study examines the issue of sex differences in ethical orientations and suggests that the enactment of social roles and the associated use of information processing strategies influence the presence of sex differences in managers\u27 ethical orientations. Managers\u27 ethical judgments and intentions to use punishments or rewards to encourage ethical behavior are the two dependent variables in the study. A 3 (prime: gender-role, work-role, no role) by 4 (ethical condition: positive egoist/positive utilitarian, positive egoist/negative utilitarian, negative egoist/positive utilitarian, and negative egoist/negative utilitarian) experimental design was applied in the efforts to answer the main research question: What is the role of a subject\u27s sex in the explanation of their ethical orientation? This design entailed the gathering of data from a probabilistic sample of 4000 U.S. managers. Two thousand of these managers were accounting and human resource managers and two thousand were sales and marketing managers. Furthermore, each group of managers was composed of 1000 males and 1000 females. The effective response rate for the survey was 11.2%. The results of this research show that the influence of a subject\u27s sex on their ethical orientation is most evident when a gender-role prime is present. When a gender role prime was not present, sex differences in ethical judgment and intention to punish or reward subordinate behavior were not significant. Furthermore, when subjects were exposed to a work role prime, those that occupied similar work roles did not differ in their ethical judgments and intentions based on their sex. Subjects that differed in their work roles, however, differed significantly in their ethical orientations. This suggests that a subject\u27s ethical orientation is dependent on the social role they are enacting and because individuals generally enact multiple social roles, their ethical orientation is not inherent. The teleology evaluation in this study was separated into egoist, or individual consequences, and utilitarian, or organizational consequences, so that the separate effects of these components on subjects\u27 ethical judgments and intentions could be studied under the separate prune conditions. It was also found that the egoist component of the teleology evaluation, along with the ethical judgment variable, were the main predictors of intentions for subjects enacting agentic work roles. In contrast, the utilitarian variable and the ethical judgment variable were the main predictors of intentions for subjects enacting communal work roles. These findings lend credence to the effort to separate the teleology evaluation in the H-V model of ethics

A Case of Appendiceal Adenocarcinoma with Clinical Benefit from FOLFOX and Bevacizumab

A 44-year-old woman presented with lower abdominal pain and bilateral ovarian masses on ultrasound. Exploratory laparotomy revealed extensive peritoneal and intra-abdominal disease and an abnormal appendix. Bilateral salpingo-oophorectomy, infracolic omentectomy, ileocolic resection and primary anastomosis were performed. Final pathology revealed a primary appendiceal adenocarcinoma, poorly differentiated, of signet ring cell type. CT scan postoperatively revealed gross residual disease. The patient was treated with FOLFOX chemotherapy combined with bevacizumab. Repeat CT scan showed a decrease in residual disease and the patient clinically improved. After her treatment has been continued for 13 months, she remains clinically well and her CT scan shows sustained disease stability. Disseminated appendiceal carcinoma is generally considered to be refractory to 5-FU-based chemotherapy and, to our knowledge, this is the first reported case of a patient with appendiceal adenocarcinoma demonstrating clinical benefit and sustained stability of disease with combination chemotherapy plus bevacizumab

Quantification of mutant huntingtin protein in cerebrospinal fluid from Huntington's disease patients.

Quantification of disease-associated proteins in the cerebrospinal fluid (CSF) has been critical for the study and treatment of several neurodegenerative disorders; however, mutant huntingtin protein (mHTT), the cause of Huntington's disease (HD), is at very low levels in CSF and, to our knowledge, has never been measured previously

Flamingo Vol. IX N 6

McDonald, George. Cover. Picture. 0 Ohio State Sun Dial. Untitled. Prose. 1. Arizona Kittykat. Untitled. Prose. 1. Sour Owl. Untitled. Prose. 3. Dartmouth Jack O\u27Lantern. Untitled. Prose. 2. Brown Jug. Untitled. Prose. 3. Illinois Siren. Untitled. Prose. 3. Kitty-Kat. Untitled. Prose. 3. Ohio State Sun Dial. Untitled. Prose. 4. Wabash Caveman. Untitled. Prose. 4. Anonymous. Untitled. Prose. 4. McDonald, George. Untitled. Picture. 8. Anonymous. Flamingo Gripes and Groans . Prose. 9. Smrcina, Orville. Untitled. Picture. 10. Anonymous. A Little Vow For Leap Year . Prose. 10. Kline, I.D. Gwendolyn Strikes Out, or, Set \u27Em Up In The Other Alley . Prose. 10. Smrcina, Orville. Untitled. Picture. 11. Anonymous. Untitled. Prose. 11. Anonymous. Untitled. Prose. 12. Anonymous. Literal Young lady . Prose. 12. Anonymous. Four-Legged Cops . Prose. 12. Anonymous. Our Leap year Poem . Prose. 13. Anonymous. The Co-Ed Thorn . Prose. 13. Anonymous. Untitled. Prose. 13. McDonald, George. Untitled. Picture. 13. Anonymous. A Bird in the Hand is Worth About Ten on the Newsstand . Prose. 15. Anonymous. I Kidnapped And Murdered Her So I Could Go To College. Prose. 18. Smith, Reed. A Photo For The Visual Minded . Picture. 16. Anonymous. Untitled. Prose. 16. Anonymous. More Photos For The Visual-Minded . Prose. 16. Anonymous. Co-Eds Obtain long-Sought Privilege: A Clever Plot Unfolded . Prose. 16. Anonymous. Candy . Prose. 16. Anonymous. Introducing-Miss 1928 . Prose. 17. Jester. Untitled Prose. 18. Lord Jeff. Untitled Prose. 18. Whirlwind. Untitled Prose. 18. Sniper. Untitled Prose. 18. Purple Parrot. Untitled Prose. 18. Minnesota Ski-U-Mah. Untitled. Prose. 18. Siren. Untitled. Prose. 18. Mink. Untitled. Prose. 18. Gargoyle. Untitled. Prose. 18. Center Colonel. Untitled. Prose. 18. Sun Dial. Untitled. Prose. 18. Anonymous. It\u27s A-Rainin\u27 Tonight . Prose. 19. Anonymous. Untitled. Prose. 19. Anonymous. The Passionate Plumber, or, Is It Cold Enough Out to Wear a Cane? . Prose. 19. McDonald, George. Untitled. Picture. 19. Anonymous. Untitled. Prose. 20. Bibby, Eugenia. The Separation of Hans and Feet Part III . Prose. 20. Smrcina, Orville. Untitled. Picture. 20. Anonymous. Untitled. Prose. 21. Anonymous. Le Quarantine Ballade . Poem. 20. Anonymous. L\u27envoi . Poem. 20. Anonymous. Book Nook . Prose. 22. Anonymous. Untitled. Prose. 23. Anonymous. Age Wisdom . Prose. 23. Brown Jug. Wrecked Romance . Prose. 24. Anonymous. Untitled. Prose. 24. Satyr. Untitled Prose. 24. Lord Jeff. Untitled Prose. 25. Mink. Have You Heard This One? Prose. 27. California Pelican. Subject to Change . Prose. 28. Yale Record. Logical . Prose. 28. Minnesota. Untitled. Prose. 28. Western Reserve Red Cat. Wotta Sight! . Prose. 29. Texas Ranger. Untitled. Prose. 29. Sniper. Untitled. Prose. 29. Anonymous. Mon Dieu . Poem. 31. Anonymous. Untitled. Poem. 31. College Humor. Untitled. Prose. 31. Kitty-Kat. Untitled. Prose. 32. Anonymous. Untitled. Prose. 32. The Old Maid. Untitled. Poem. 32

Art is Not Research. Research is not Art.

Art is not Research. Research is not Art. is a multimedia, multi-site participatory installation by a collective of artists and researchers from Calgary, Toronto, and Lancaster; it is informed by these contexts. It reflects the tensions between how "participants"are treated in participatory art and interaction research. It offers a framework through which we can explore how epistemologies might evolve in a blending between Art and Research. Visitors download the paper to read, critically reflect on the relationship between art and research, and experientially engage with the material through a series of creative prompts. A performance variation of the piece will be performed in-person and online through the ACM SIGCHI Conference on Human Factors in Computing Systems alt.chi track

Time contracts and temporal precision declines when the mind wanders

Our perception of time varies considerably from moment to moment but how this variability relates to endogenous fluctuations in attentional states remains poorly understood. Here we tested the hypothesis that perceptual decoupling during mind wandering would distort interval timing. In two studies with different visual interval timing paradigms, we found that mind wandering states were characterized by underestimation of intervals and a decline in temporal discrimination. Further analyses suggested that temporal contraction during mind wandering, but not a decline in temporal discrimination, could be attributed in part to attentional lapses. These results highlight the role of transient fluctuations in attentional states in intra-individual variability in time perception and have implications for the behavioral markers, and costs and benefits, of mind wandering

Cellular sheddases are induced by Merkel Cell Polyomavirus Small Tumour Antigen to mediate cell dissociation and invasiveness

Merkel cell carcinoma (MCC) is an aggressive skin cancer with a high propensity for recurrence and metastasis. Merkel cell polyomavirus (MCPyV) is recognised as the causative factor in the majority of MCC cases. The MCPyV small tumour antigen (ST) is considered to be the main viral transforming factor, however potential mechanisms linking ST expression to the highly metastatic nature of MCC are yet to be fully elucidated. Metastasis is a complex process, with several discrete steps required for the formation of secondary tumour sites. One essential trait that underpins the ability of cancer cells to metastasise is how they interact with adjoining tumour cells and the surrounding extracellular matrix. Here we demonstrate that MCPyV ST expression disrupts the integrity of cell-cell junctions, thereby enhancing cell dissociation and implicate the cellular sheddases, A disintegrin and metalloproteinase (ADAM) 10 and 17 proteins in this process. Inhibition of ADAM 10 and 17 activity reduced MCPyV ST-induced cell dissociation and motility, attributing their function as critical to the MCPyV-induced metastatic processes. Consistent with these data, we confirm that ADAM 10 and 17 are upregulated in MCPyV-positive primary MCC tumours. These novel findings implicate cellular sheddases as key host cell factors contributing to virus-mediated cellular transformation and metastasis. Notably, ADAM protein expression may be a novel biomarker of MCC prognosis and given the current interest in cellular sheddase inhibitors for cancer therapeutics, it highlights ADAM 10 and 17 activity as a novel opportunity for targeted interventions for disseminated MCC

Assessing sulfate reduction and methane cycling in a high salinity pore water system in the northern Gulf of Mexico

This paper is not subject to U.S. copyright. The definitive version was published in Marine and Petroleum Geology 25 (2008): 942-951, doi:10.1016/j.marpetgeo.2008.01.016.Pore waters extracted from 18 piston cores obtained on and near a salt-cored bathymetric high in Keathley Canyon lease block 151 in the northern Gulf of Mexico contain elevated concentrations of chloride (up to 838 mM) and have pore water chemical concentration profiles that exhibit extensive departures (concavity) from steady-state (linear) diffusive equilibrium with depth. Minimum δ13C dissolved inorganic carbon (DIC) values of −55.9‰ to −64.8‰ at the sulfate–methane transition (SMT) strongly suggest active anaerobic oxidation of methane (AOM) throughout the study region. However, the nonlinear pore water chemistry-depth profiles make it impossible to determine the vertical extent of active AOM or the potential role of alternate sulfate reduction pathways. Here we utilize the conservative (non-reactive) nature of dissolved chloride to differentiate the effects of biogeochemical activity (e.g., AOM and/or organoclastic sulfate reduction) relative to physical mixing in high salinity Keathley Canyon sediments. In most cases, the DIC and sulfate concentrations in pore waters are consistent with a conservative mixing model that uses chloride concentrations at the seafloor and the SMT as endmembers. Conservative mixing of pore water constituents implies that an undetermined physical process is primarily responsible for the nonlinearity of the pore water-depth profiles. In limited cases where the sulfate and DIC concentrations deviated from conservative mixing between the seafloor and SMT, the δ13C-DIC mixing diagrams suggest that the excess DIC is produced from a 13C-depleted source that could only be accounted for by microbial methane, the dominant form of methane identified during this study. We conclude that AOM is the most prevalent sink for sulfate and that it occurs primarily at the SMT at this Keathley Canyon site.This work was supported by DOE’s National Energy Technology Laboratory, the Office of Naval Research, and the Naval Research Laboratory. J.W.P was supported by a USGS Mendenhall Postdoctoral Research Fellowship Program during preparation of this manuscript

Social preferences, accountability, and wage bargaining

We assess the extent of preferences for employment in a collective wage bargaining situation with heterogeneous workers. We vary the size of the union and introduce a treatment mechanism transforming the voting game into an individual allocation task. Our results show that highly productive workers do not take employment of low productive workers into account when making wage proposals, regardless of whether insiders determine the wage or all workers. The level of pro-social preferences is small in the voting game, while it increases as the game is transformed into an individual allocation task. We interpret this as an accountability effect