The representation of women who have sex with women (WSW) in sexual health promotion in England: a frame analysis

Women who have sex with women (WSW) are a marginalised group. WSW are assumed to be at low risk of sexually transmitted infections (STIs). However, they have similar rates of STIs to women who have sex exclusively with men. A lack of accurate and relevant sexual health information for WSW has been identified and highlighted as a barrier to good sexual health in this group. This study aims to explore how WSW and their STI risk are represented in sexual health promotion in England. Methods: Organisations that produced sexual health promotion campaigns or policy were identified using a three-step Google search. Up to three materials from each campaign were chosen for analysis alongside policy documents. Frame analysis was used to identify and develop a thematic framework that identified common themes and assumptions in the data. Results: 5 policy documents and 42 campaign materials were analysed (n=47). Nine frames were identified and used to discuss the two overarching themes that emerged from these: over-representation of the penis and under-representation of WSW and their relevant sexual practices. Discussion: This study suggests an androcentric and heteronormative framing of sexual health promotion, resulting in the erasure of WSW. Erasure perpetuates false narratives of low STI risk and symbolically annihilates this group, a form of symbolic violence. To address this issue, I suggest empowering WSW by acknowledging this erasure and developing new sexual health campaigns and policy with the participation of this group

Multimodal imaging of thyroid cancer

Purpose of review Thyroid cancer is the most common endocrine cancer in adults with rising incidence. Challenges in imaging thyroid cancer are twofold: distinguishing thyroid cancer from benign thyroid nodules, which occur in 50% of the population over 50 years; and correct staging of thyroid cancer to facilitate appropriate radical surgery in a single session. The clinical management of thyroid cancer patients has been covered in detail by the 2015 guidelines of the American Thyroid Association (ATA). The purpose of this review is to state the principles underlying optimal multimodal imaging of thyroid cancer and aid clinicians in avoiding important pitfalls. Recent findings Recent additions to the literature include assessment of ultrasound-based scoring systems to improve selection of nodules for fine needle biopsy (FNB) and the evaluation of new radioactive tracers for imaging thyroid cancer. Summary The mainstay of diagnosing thyroid cancer is thyroid ultrasound with ultrasound-guided FNB. Contrast-enhanced computed tomography and PET with [18F]-fluorodeoxyglucose (FDG) and MRI are reserved for advanced and/or recurrent cases of differentiated thyroid cancer and anaplastic thyroid cancer, while [18F]FDOPA and [68Ga]DOTATOC are the preferred tracers for medullary thyroid cancer.publishedVersio

Perjanjian AATHP (ASEAN Agreement on Transboundary Haze Pollution) Dalam Menanggapi Isu Kabut Asap Lintas Batas di Asia Tenggara Pasca Indonesia Meratifikasi Perjanjian Tahun 2014

Tujuan diadakannya atau dibentuknya AATHP ini adalah untuk menanggulangi polusi asap agar tidak menyebar keluar batas wilayah suatu negara negara. Indonesia meratifikasi AATHP pada 16 September 2014 dengan Undang-Undang Nomor 26 Tahun 2014 tentang Pengesahan ASEAN Agreement On Transboundary Haze Pollution dan menjadi negara terakhir yang meratifikasi AATHP. Instrumen ratifikasinya sendiri baru diserahkan ke sekretariat ASEAN pada 20 Januari 2015. Indonesia akhirnya meratifikasi persetujuan tersebut sebagai bentuk keseriusan penanganan pencemaran asap lintas batas akibat dari karhutla yang terjadi di wilayah Indonesia. Setelah proses ratifikasi AATHP, langkah selanjutnya yang harus diambil oleh pemerintah Indonesia adalah dengan melakukan implementasi perjanjian internasional tersebut

Pretherapeutic 124I dosimetry reliably predicts intratherapeutic blood kinetics of 131I in patients with differentiated thyroid carcinoma receiving high therapeutic activities

Item does not contain fulltextAIM: The aim of this study was to assess the agreement between predicted blood uptake values using I and actually measured I blood uptake values (reference) in patients with differentiated thyroid carcinoma receiving largely high therapeutic activities. PATIENTS AND METHODS: Fourteen patients were analyzed retrospectively, who underwent a series of both pretherapeutic and intratherapeutic blood sampling using median I activities of 23 MBq and median therapy I activities of 10 GBq. Data of five blood samples from each patient were analyzed. Lin's concordance correlation coefficient analysis was carried out to assess the kinetic agreement. The time-integrated I activity coefficient (TIAC) for the blood compartment and the effective I clearance time (ECT), expressed as effective I half-life on the basis of a monoexponential model, were ascertained. For each patient, the (intrapatient) percentage differences between pretherapeutic and intratherapeutic TIACs and ECTs were calculated. The (interpatient) difference in TIACs and ECTs between pretherapy and intratherapy groups was evaluated using the Mann-Whitney U-test. RESULTS: Lin's concordance correlation coefficient was at least 0.97, indicating substantial kinetic agreement between pretherapeutic and intratherapeutic radioiodine kinetics. The mean (median)+/-SD (range) of the absolute percentage difference was 9% (11%)+/-7% (0.33-20%) for the TIAC and 11% (10%)+/-10% (0-23%) for the ECT. A slightly higher median TIAC was observed in intratherapy (2.8 vs. 3.3 h), but this was not statistically significant (P=0.15), whereas no remarkable ECT difference (P=0.62) was found. CONCLUSION: The pretherapeutic blood kinetics derived from diagnostic I activities provides a reliable estimation of the intratherapeutic I blood kinetics in patients receiving largely high therapy activities, showing its potential for radioiodine treatment planning

The Impact of Somatostatin Receptor-Directed PET/CT on the Management of Patients with Neuroendocrine Tumor: A Systematic Review and Meta-Analysis

Somatostatin receptor (SSTR) imaging is widely used for guiding the management of neuroendocrine tumor (NET) patients. (68)Ga-DOTATATE approval by the U.S. Food and Drug Administration has triggered widespread clinical interest in SSTR PET/CT throughout the United States. Here, we performed a systematic review and meta-analysis to evaluate the impact of SSTR PET/CT on the management of patients with NETs. Methods: A comprehensive literature search was performed using The National Center for Biotechnology Information PubMed online database, applying the following key words: "management" AND "PET" AND "neuroendocrine". Fourteen of 190 studies were deemed suitable based on the following inclusion criteria: original research, cohort study, number of patients 10 or more, and reported change in management after SSTR PET/CT. Change in management across studies was determined by a random-effects model. Results: A total of 1,561 patients were included. Overall, change in management occurred in 44% (range, 16%-71%) of NET patients after SSTR PET/CT. In 4 of 14 studies, SSTR PET/CT was performed after an (111)In-Octreotide scan. In this subgroup, additional information by SSTR PET/CT led to a change in management in 39% (range, 16%-71%) of patients. Seven of 14 studies differentiated between inter- and intramodality changes, with most changes being intermodality (77%; intramodality, 23%). Conclusion: The management was changed in more than one third of patients undergoing SSTR PET/CT even when performed after an (111)In-Octreotide scan. Intermodality changes were 3 times more likely than intramodality changes, underlining the clinical impact of SSTR PET/CT

Monitoring reaction speeds of polymerizable resins under UV radiation

Translated from French (Composites 1988 v. 28(3) p. 180-185)Available from British Library Document Supply Centre- DSC:9022.0601(BISI-EM-Trans--285)T / BLDSC - British Library Document Supply CentreSIGLEGBUnited Kingdo