238 research outputs found
The Spatial Heterogeneity between Japanese Encephalitis Incidence Distribution and Environmental Variables in Nepal
- Author
- A Bhattachan
- Ajit Rayamajhi
- AM Ellis
- BD Lindenbach
- Benjamin J. Cowling
- Cyril Caminade
- D Gregory
- Daniel E. Impoinvil
- DG Kleinbaum
- DWS Wong
- EA Gould
- EE Richards
- G Wang
- Geeta Shakya
- GR Pant
- GR Pant
- I Vythilingam
- J Partridge
- J Shaman
- J Shaman
- JB Gingrich
- JG Olson
- JN Hanna
- L Anselin
- M Kulldorff
- M Mogi
- M Takahashi
- Matthew Baylis
- MC Wimberly
- MD Ward
- MD Zimmerman
- P Bi
- P Masuoka
- PK Das
- Ram Padarath Bichha
- RF Darsie Jr
- RF Darsie Jr
- RF Darsie Jr
- RJ Hijmans
- RJ Marshall
- S Openshaw
- SD Pant
- SM Hsu
- T Solomon
- T Umenai
- TF Wierzba
- TJ Henrich
- Tom Solomon
- TP Endy
- US Murty
- W Liu
- W. William Schluter
- WJ Landesman
- WK Reisen
- Publication venue
- Public Library of Science
- Publication date
- 21/07/2011
- Field of study
To identify potential environmental drivers of Japanese Encephalitis virus (JE) transmission in Nepal, we conducted an ecological study to determine the spatial association between 2005 Nepal JE incidence, and climate, agricultural, and land-cover variables at district level.District-level data on JE cases were examined using Local Indicators of Spatial Association (LISA) analysis to identify spatial clusters from 2004 to 2008 and 2005 data was used to fit a spatial lag regression model with climate, agriculture and land-cover variables.Prior to 2006, there was a single large cluster of JE cases located in the Far-West and Mid-West terai regions of Nepal. After 2005, the distribution of JE cases in Nepal shifted with clusters found in the central hill areas. JE incidence during the 2005 epidemic had a stronger association with May mean monthly temperature and April mean monthly total precipitation compared to mean annual temperature and precipitation. A parsimonious spatial lag regression model revealed, 1) a significant negative relationship between JE incidence and April precipitation, 2) a significant positive relationship between JE incidence and percentage of irrigated land 3) a non-significant negative relationship between JE incidence and percentage of grassland cover, and 4) a unimodal non-significant relationship between JE Incidence and pig-to-human ratio.JE cases clustered in the terai prior to 2006 where it seemed to shift to the Kathmandu region in subsequent years. The spatial pattern of JE cases during the 2005 epidemic in Nepal was significantly associated with low precipitation and the percentage of irrigated land. Despite the availability of an effective vaccine, it is still important to understand environmental drivers of JEV transmission since the enzootic cycle of JEV transmission is not likely to be totally interrupted. Understanding the spatial dynamics of JE risk factors may be useful in providing important information to the Nepal immunization program
Search for Kaluza-Klein Graviton Emission in ppˉ Collisions at s=1.8 TeV using the Missing Energy Signature
- Author
- Acosta D
- Affolder T
- Akimoto H
- Albrow MG
- Ambrose D
- Amidei D
- Anikeev K
- Antos J
- Apollinari G
- Arisawa T
- Artikov A
- Asakawa T
- Ashmanskas W
- Azfar F
- Azzi-Bacchetta P
- Bacchetta N
- Bachacou H
- Badgett W
- Bailey S
- Barbaro-Galtieri A
- Barnes VE
- Barnett BA
- Baroiant S
- Barone M
- Bauer G
- Bedeschi F
- Behari S
- Belforte S
- Bell WH
- Bellettini G
- Bellinger J
- Benjamin D
- Bensinger J
- Beretvas A
- Berryhill J
- Bhatti A
- Binkley M
- Bisello D
- Bishai M
- Blair RE
- Blocker C
- Bloom K
- Blumenfeld B
- Blusk SR
- Bocci A
- Bodek A
- Bolla G
- Bolshov A
- Bonushkin Y
- Bortoletto D
- Boudreau J
- Brandl A
- Bromberg C
- Brozovic M
- Brubaker E
- Bruner N
- Budagov J
- Budd HS
- Burkett K
- Busetto G
- Byrum KL
- Cabrera S
- Calafiura P
- Campbell M
- Carithers W
- Carlsmith D
- Carlson J
- Caskey W
- Castro A
- Cauz D
- Cecco SD
- Cerri A
- Cerrito L
- Chan AW
- Chang PS
- Chang PT
- Chapman J
- Chen C
- Chen YC
- Cheng MT
- Chertok M
- Chiarelli G
- Chirikov-Zorin I
- Chlachidze G
- Chlebana F
- Christofek L
- Chu ML
- Chung JY
- Chung WH
- Chung YS
- Ciobanu CI
- Clark AG
- Coca M
- Connolly A
- Convery M
- Conway J
- Cordelli M
- Cranshaw J
- Culbertson R
- D'Auria S
- D'Onofrio M
- da Costa JG
- Dagenhart D
- de Barbaro P
- de Troconiz JF
- de Troconiz JF
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- Dell'Orso M
- Demers S
- Demortier L
- Deninno M
- Denis RS
- Derwent PF
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- Dionisi C
- Dittmann JR
- Dominguez A
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- Dorigo T
- Eddy N
- Einsweiler K
- Engels E
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- Errede D
- Errede S
- Eusebi R
- Fan Q
- Farrington S
- Feild RG
- Fernandez JP
- Ferretti C
- Field RD
- Fiori I
- Flaugher B
- Flores-Castillo LR
- Foster GW
- Franklin M
- Freeman J
- Friedman J
- Fukui Y
- Furic I
- Galeotti S
- Gallas A
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- Garfinkel AF
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- Publication venue
- 'American Physical Society (APS)'
- Publication date
- 01/01/2004
- Field of study
We report on a search for direct Kaluza-Klein graviton production in a data
sample of 84 pb−1 of \ppb collisions at s = 1.8 TeV, recorded
by the Collider Detector at Fermilab. We investigate the final state of large
missing transverse energy and one or two high energy jets. We compare the data
with the predictions from a 3+1+n-dimensional Kaluza-Klein scenario in which
gravity becomes strong at the TeV scale. At 95% confidence level (C.L.) for
n=2, 4, and 6 we exclude an effective Planck scale below 1.0, 0.77, and 0.71
TeV, respectively.Comment: Submitted to PRL, 7 pages 4 figures/Revision includes 5 figure
Measurement of the average time-integrated mixing probability of b-flavored hadrons produced at the Tevatron
- Author
- Acosta D
- Affolder T
- Akimoto H
- Albrow MG
- Ambrose D
- Amidei D
- Anikeev K
- Antos J
- Apollinari G
- Arisawa T
- Artikov A
- Asakawa T
- Ashmanskas W
- Azfar F
- Azzi-Bacchetta P
- Bacchetta N
- Bachacou H
- Badgett W
- Bailey S
- Barbaro-Galtieri A
- Barnes VE
- Barnett BA
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- Zucchelli Spatra AK
- Zucchelli Sychev D
- Zucchelli SZetti F
- Publication venue
- 'American Physical Society (APS)'
- Publication date
- 08/09/2003
- Field of study
We have measured the number of like-sign (LS) and opposite-sign (OS) lepton
pairs arising from double semileptonic decays of b and bˉ-hadrons,
pair-produced at the Fermilab Tevatron collider. The data samples were
collected with the Collider Detector at Fermilab (CDF) during the 1992-1995
collider run by triggering on the existence of μμ and eμ candidates
in an event. The observed ratio of LS to OS dileptons leads to a measurement of
the average time-integrated mixing probability of all produced b-flavored
hadrons which decay weakly, χˉ=0.152±0.007 (stat.) ±0.011
(syst.), that is significantly larger than the world average χˉ=0.118±0.005.Comment: 47 pages, 10 figures, 15 tables Submitted to Phys. Rev.
A common genetic network underlies substance use disorders and disruptive or externalizing disorders
- Author
- A Hinney
- AF Martinez
- AM White
- American Psychiatric Association
- AW Bergen
- Benjamin D. Solomon
- BM Neale
- BR Horner
- BS Molina
- BSG Molina
- BZ Yang
- BZ Yang
- C Johnson
- CM Szobot
- DA Pineda
- EJ Khantzian
- ER Martin
- ES Ercan
- F Ducci
- FX Castellanos
- G Poelmans
- GR Uhl
- GR Uhl
- GR Uhl
- GR Uhl
- GR Uhl
- HC Stanescu
- J Biederman
- J Elia
- J Gelernter
- JC Long
- JD Palacio
- JM Anaya
- Jorge I. Vélez
- L DeMilio
- LM Karkowski
- M Arcos-Burgos
- M Arcos-Burgos
- M Arcos-Burgos
- M Arcos-Burgos
- M Jain
- M Jain
- M Ribases
- M Ribases
- Mauricio Arcos-Burgos
- Maximilian Muenke
- MD Li
- MT Acosta
- MT Acosta
- MT Tsuang
- O Bukstein
- QR Liu
- RA Chambers
- RA Spritz
- S Kuperman
- S Visser
- SP David
- T Reich
- TE Wilens
- TE Wilens
- WE Pelham
- WR True
- Y Jin
- Publication venue
- Springer-Verlag
- Publication date
- 01/01/2012
- Field of study
Here we summarize evidence obtained by our group during the last two decades, and contrasted it with a review of related data from the available literature to show that behavioral syndromes involving attention deficit/hyperactivity disorder (ADHD), externalizing disorders, and substance-use disorder (SUD) share similar signs and symptoms (i.e., have a biological basis as common syndromes), physiopathological and psychopathological mechanisms, and genetic factors. Furthermore, we will show that the same genetic variants harbored in different genes are associated with different syndromes and that non-linear interactions between genetic variants (epistasis) best explain phenotype severity, long-term outcome, and response to treatment. These data have been depicted in our studies by extended pedigrees, where ADHD, externalizing symptoms, and SUD segregate and co-segregate. Finally, we applied here a new formal network analysis using the set of significantly replicated genes that have been shown to be either associated and/or linked to ADHD, disruptive behaviors, and SUD in order to detect significantly enriched gene categories for protein and genetic interactions, pathways, co-expression, co-localization, and protein domain similarity. We found that networks related to pathways involved in axon guidance, regulation of synaptic transmission, and regulation of transmission of nerve impulse are overrepresented. In summary, we provide compiled evidence of complex networks of genotypes underlying a wide phenotype that involves SUD and externalizing disorders
Measurement of the tt¯tt¯ production cross section in pp collisions at √s=13 TeV with the ATLAS detector
- Author
- Aad G
- Abbott B
- Abbott DC
- Abed Abud A
- Abeling K
- Abhayasinghe DK
- Abidi SH
- Abramowicz H
- Abreu H
- Abulaiti Y
- Abusleme Hoffman AC
- Acharya BS
- Achkar B
- Adam Bourdarios C
- Adam L
- Adamczyk L
- Adamek L
- Adelman J
- Adiguzel A
- Adorni S
- Adye T
- Affolder AA
- Afik Y
- Agapopoulou C
- Agaras MN
- Agarwala J
- Aggarwal A
- Agheorghiesei C
- Aguilar-Saavedra JA
- Ahmad A
- Ahmadov F
- Ahmed WS
- Ai X
- Aielli G
- Akatsuka S
- Akbiyik M
- Akimov AV
- Al Khoury K
- Alberghi GL
- Albert J
- Alconada Verzini MJ
- Alderweireldt S
- Aleksa M
- Aleksandrov IN
- Alexa C
- Alexopoulos T
- Alfonsi A
- Alfonsi F
- Alhroob M
- Ali B
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- Zhemchugov A
- Zheng Z
- Zhong D
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- Zhukov K
- Zhulanov V
- Zieminska D
- Zimine NI
- Zimmermann S
- Ziolkowski M
- Zoccoli A
- Zoch K
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- Zwalinski L
- Åkesson TPA
- Öncel ÖO
- Ženiš T
- Živković L
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 16/11/2021
- Field of study
A measurement of four-top-quark production using proton-proton collision data at a centre-of-mass energy of 13 TeV collected by the ATLAS detector at the Large Hadron Collider corresponding to an integrated luminosity of 139 fb−1 is presented. Events are selected if they contain a single lepton (electron or muon) or an opposite-sign lepton pair, in association with multiple jets. The events are categorised according to the number of jets and how likely these are to contain b-hadrons. A multivariate technique is then used to discriminate between signal and background events. The measured four-top-quark production cross section is found to be 26+17−15 fb, with a corresponding observed (expected) significance of 1.9 (1.0) standard deviations over the background-only hypothesis. The result is combined with the previous measurement performed by the ATLAS Collaboration in the multilepton final state. The combined four-top-quark production cross section is measured to be 24+7−6 fb, with a corresponding observed (expected) signal significance of 4.7 (2.6) standard deviations over the background-only predictions. It is consistent within 2.0 standard deviations with the Standard Model expectation of 12.0 ± 2.4 fb
Measurements of W+W−+ ≥ 1 jet production cross-sections in pp collisions at s = 13 TeV with the ATLAS detector
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- Zemaityte G
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- Zhao Y
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- Zhemchugov A
- Zheng Z
- Zhong D
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- Zhukov K
- Zhulanov V
- Zieminska D
- Zimine NI
- Zimmermann S
- Zinonos Z
- Ziolkowski M
- Zoccoli A
- Zoch K
- Zorbas TG
- Zou R
- Zou W
- Zwalinski L
- Åkesson TPA
- Öncel ÖO
- Ženiš T
- Živković L
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/06/2021
- Field of study
Fiducial and differential cross-section measurements of W+W− production in
association with at least one hadronic jet are presented. These measurements are sensitive
to the properties of electroweak-boson self-interactions and provide a test of perturbative
quantum chromodynamics and the electroweak theory. The analysis is performed using
proton-proton collision data collected at p
s = 13TeV with the ATLAS experiment, corresponding
to an integrated luminosity of 139 fb−1. Events are selected with exactly one oppositely
charged electron-muon pair and at least one hadronic jet with a transverse momentum
of pT > 30 GeV and a pseudorapidity of |�| < 4.5. After subtracting the background
contributions and correcting for detector effects, the jet-inclusive W+W−+ � 1 jet fiducial
cross-section and W+W−+ jets differential cross-sections with respect to several kinematic
variables are measured. These measurements include leptonic quantities, such as the lepton
transverse momenta and the transverse mass of the W+W− system, as well as jet-related
observables such as the leading jet transverse momentum and the jet multiplicity. Limits on
anomalous triple-gauge-boson couplings are obtained in a phase space where interference
between the Standard Model amplitude and the anomalous amplitude is enhanced
Measurement of the energy asymmetry in t(t)over-barj production at 13 TeV with the ATLAS experiment and interpretation in the SMEFT framework
- Author
- Aad G
- Abbott B
- Abbott DC
- Abeling K
- Abhayasinghe DK
- Abidi SH
- Aboulhorma A
- Abramowicz H
- Abreu H
- Abud A Abed
- Abulaiti Y
- Abusleme Hoffman AC
- Acharya BS
- Achkar B
- Adam L
- Adamczyk L
- Adamek L
- Addepalli S
- Adelman J
- Adiguzel A
- Adorni S
- Adye T
- Affolder AA
- Afik Y
- Agapopoulou C
- Agaras MN
- Agarwala J
- Aggarwal A
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- Aguilar-Saavedra JA
- Ahmad A
- Ahmadov F
- Ahmed WS
- Ai X
- Aielli G
- Aizenberg I
- Akatsuka S
- Akbiyik M
- Akesson TPA
- Akimov A
- Al Khoury K
- Alberghi GL
- Albert J
- Albicocco P
- Alconada Verzini MJ
- Alderweireldt S
- Aleksa M
- Aleksandrov IN
- Alexa C
- Alexopoulos T
- Alfonsi A
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- Zagazeta LF Gutierrez
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- Zhang Z
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- Zhemchugov A
- Zheng Z
- Zhong D
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- Zormpa O
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- Publication venue
- 'Springer Fachmedien Wiesbaden GmbH'
- Publication date
- 28/04/2022
- Field of study
A measurement of the energy asymmetry in jet-associated top-quark pair production is presented using 139fb−1
139
fb
-
1
of data collected by the ATLAS detector at the Large Hadron Collider during pp collisions at s=13TeV
s
=
13
TeV
. The observable measures the different probability of top and antitop quarks to have the higher energy as a function of the jet scattering angle with respect to the beam axis. The energy asymmetry is measured in the semileptonic ttˉ
t
t
¯
decay channel, and the hadronically decaying top quark must have transverse momentum above 350GeV
350
GeV
. The results are corrected for detector effects to particle level in three bins of the scattering angle of the associated jet. The measurement agrees with the SM prediction at next-to-leading-order accuracy in quantum chromodynamics in all three bins. In the bin with the largest expected asymmetry, where the jet is emitted perpendicular to the beam, the energy asymmetry is measured to be −0.043±0.020
-
0.043
±
0.020
, in agreement with the SM prediction of −0.037±0.003
-
0.037
±
0.003
. Interpreting this result in the framework of the Standard Model effective field theory (SMEFT), it is shown that the energy asymmetry is sensitive to the top-quark chirality in four-quark operators and is therefore a valuable new observable in global SMEFT fits
Determination of the parton distribution functions of the proton using diverse ATLAS data from pp collisions at √s = 7, 8 and 13 TeV
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- Zhemchugov A
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- Zimine NI
- Zimmermann S
- Zinsser J
- Ziolkowski M
- Zoccoli A
- Zoch K
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- Zwalinski L
- Åkesson TPA
- Öncel ÖO
- Ženiš T
- Živković L
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/01/2022
- Field of study
This paper presents an analysis at next-to-next-to-leading order in the theory of quantum chromodynamics for the determination of a new set of proton parton distribution functions using diverse measurements in pp collisions at \sqrt{s} = 7, 8 and 13 TeV, performed by the ATLAS experiment at the Large Hadron Collider, together with deep inelastic scattering data from ep collisions at the HERA collider. The ATLAS data sets considered are differential cross-section measurements of inclusive W^{±} and Z/gamma^{*} boson production, W^{±} and Z boson production in association with jets, t\bar{t} production, inclusive jet production and direct photon production. In the analysis, particular attention is paid to the correlation of systematic uncertainties within and between the various ATLAS data sets and to the impact of model, theoretical and parameterisation uncertainties. The resulting set of parton distribution functions is called ATLASpdf21
Modelling and computational improvements to the simulation of single vector-boson plus jet processes for the ATLAS experiment
- Author
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- Abbott B
- Abbott DC
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- Abhayasinghe DK
- Abidi SH
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- Zheng Z
- Zhong D
- Zhou B
- Zhou C
- Zhou H
- Zhou N
- Zhou Y
- Zhu C
- Zhu CG
- Zhu H
- Zhu HL
- Zhu J
- Zhu Y
- Zhuang X
- Zhukov K
- Zhulanov V
- Zieminska D
- Zimine NI
- Zimmermann S
- Zinsser J
- Ziolkowski M
- Zivkovic L
- Zoccoli A
- Zoch K
- Zorbas TG
- Zormpa O
- Zou W
- Zwalinski L
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/01/2022
- Field of study
This paper presents updated Monte Carlo configurations used to model the production of single electroweak vector bosons (W, Z/gamma*) in association with jets in proton-proton collisions for the ATLAS experiment at the Large Hadron Collider. Improvements pertaining to the electroweak input scheme, parton-shower splitting kernels and scale-setting scheme are shown for multi-jet merged configurations accurate to next-to-leading order in the strong and electroweak couplings. The computational resources required for these set-ups are assessed, and approximations are introduced resulting in a factor three reduction of the per-event CPU time without affecting the physics modelling performance. Continuous statistical enhancement techniques are introduced by ATLAS in order to populate low cross-section regions of phase space and are shown to match or exceed the generated effective luminosity. This, together with the lower per-event CPU time, results in a 50% reduction in the required computing resources compared to a legacy set-up previously used by the ATLAS collaboration. The set-ups described in this paper will be used for future ATLAS analyses and lay the foundation for the next generation of Monte Carlo predictions for single vector-boson plus jets production
Measurements of sensor radiation damage in the ATLAS inner detector using leakage currents
- Author
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- Publication venue
- IOP
- Publication date
- 01/01/2021
- Field of study
Non-ionizing energy loss causes bulk damage to the silicon sensors of the ATLAS pixel and strip detectors. This damage has important implications for data-taking operations, charged-particle track reconstruction, detector simulations, and physics analysis. This paper presents simulations and measurements of the leakage current in the ATLAS pixel detector and semiconductor tracker as a function of location in the detector and time, using data collected in Run 1 (2010–2012) and Run 2 (2015–2018) of the Large Hadron Collider. The extracted fluence shows a much stronger |z|-dependence in the innermost layers than is seen in simulation. Furthermore, the overall fluence on the second innermost layer is significantly higher than in simulation, with better agreement in layers at higher radii. These measurements are important for validating the simulation models and can be used in part to justify safety factors for future detector designs and interventions.publishedVersio
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