Response to: 'On the approach for determining association between changes in marital quality and cardiovascular disease risk factors' by MM Pike

No abstract available

Referential focus moderates depression-linked attentional avoidance of positive information.

While there is consensus that depression is associated with a memory bias characterized by reduced retrieval of positive information that is restricted to information that had been self-referentially processed, there is less agreement concerning whether depression is characterized by an attention bias involving reduced attention to positive information. However, unlike memory research, previous attention research has not systematically examined the potential role of referential processing focus. The present study tested the hypothesis that evidence of depression-linked attentional avoidance of positive information would be more readily obtained following the self-referential processing of such information. We assessed attentional responding to positive information (and also to negative information) using a dot-probe procedure, after this information had been processed either in a self-referential or other-referential manner. The findings lend support to the hypothesis under scrutiny. Participants scoring high in depression score exhibited reduced attention to positive information compared to those scoring low in depression score, but only when this information had been processed in a self-referential manner. These findings may shed light on the mechanisms that underpin attentional selectivity in depression, while potentially also helping to account for inconsistencies in previous literature

Changes in marital quality over 6 years and its association with cardiovascular disease risk factors in men: findings from the ALSPAC prospective cohort study

Background: Marital relationship quality has been suggested to have independent effects on cardiovascular health outcomes. This study investigates the association between changes in marital relationship quality and cardiovascular disease (CVD) risk factors in men. Methods: We used data from The Avon Longitudinal Study of Parents and Children, a prospective birth cohort study (Bristol, UK). Our baseline sample was restricted to married study fathers with baseline relationship and covariate data (n=2496). We restricted final analysis (n=620) to those with complete outcome, exposure and covariate data, who were married and confirmed the study child’s father at 6.4 years and 18.8 years after baseline. Relationship quality was measured at baseline and 6.4 years and operationalised as consistently good, improving, deteriorating or consistently poor relationship. We measured CVD risk factors of blood pressure, resting heart rate, body mass index, lipid profile and fasting glucose at 18.8 years after baseline. Results: Improving relationships were associated with lower levels of low-density lipoprotein (−0.25 mmol/L, 95% CI −0.46 to −0.03) and relative reduction of body mass index (−1.07 kg/m2, 95% CI −1.73 to −0.42) compared with consistently good relationships, adjusting for confounders. Weaker associations were found between improving relationships and total cholesterol (−0.24 mmol/L, 95% CI −0.48 to 0.00) and diastolic blood pressure (−2.24 mm Hg, 95% CI −4.59 to +0.11). Deteriorating relationships were associated with worsening diastolic blood pressure (+2.74 mm Hg, 95% CI 0.50 to 4.98). Conclusions: Improvement and deterioration of longitudinal relationship quality appears associated with respectively positive and negative associations with a range of CVD risk factors

Different measures of auditory and visual stroop interference and their relationship to speech intelligibility in noise

Inhibition – the ability to suppress goal-irrelevant information – is thought to be an important cognitive skill in many situations, including speech-in-noise (SiN) perception. One way to measure inhibition is by means of Stroop tasks, in which one stimulus dimension must be named while a second, more prepotent dimension is ignored. The to-be-ignored dimension may be relevant or irrelevant to the target dimension, and the inhibition measure – Stroop interference (SI) – is calculated as the reaction time difference between the relevant and irrelevant conditions. Both SiN perception and inhibition are suggested to worsen with age, yet attempts to connect age-related declines in these two abilities have produced mixed results. We suggest that the inconsistencies between studies may be due to methodological issues surrounding the use of Stroop tasks. First, the relationship between SI and SiN perception may differ depending on the modality of the Stroop task; second, the traditional SI measure may not account for generalized slowing or sensory declines, and thus may not provide a pure interference measure. We investigated both claims in a group of 50 older adults, who performed two Stroop tasks (visual and auditory) and two SiN perception tasks. For each Stroop task, we calculated interference scores using both the traditional difference measure and methods designed to address its various problems, and compared the ability of these different scoring methods to predict SiN performance, alone and in combination with hearing ability. Results from the two Stroop tasks were uncorrelated and had different relationships to SiN perception. Changing the scoring method altered the nature of the predictive relationship between Stroop scores and SiN perception, which was additionally influenced by hearing ability. These findings raise questions about the extent to which different Stroop tasks and/or scoring methods measure the same aspect of cognition. They also highlight the importance of considering additional variables such as hearing ability when analysing cognitive variables

Learning to play 3 x 3 games : neural networks as bounded-rational players

We present a neural network methodology for learning game-playing rules in general. Existing research suggests learning to find a Nash equilibrium in a new game is too difficult a task for a neural network, but says little about what it will do instead. We observe that a neural network trained to find Nash equilibria in a known subset of games, will use self-taught rules developed endogenously when facing new games. These rules are close to payoff dominance and its best response. Our findings are consistent with existing experimental results, both in terms of subject's methodology and success rates

Identification of Genomic Variants Causing Variation in Quantitative Traits: A Review

publishedVersio

The elusive theory of everything

We applaud Baumert and colleagues’ ambitious idea to integrate personality processes, structure, and development into a single general theory with the aim of fully explaining people’s behavior across situations. However, we argue that building a general theory of human behavior, similarly to a Theory of Everything, may not only be less feasible, but also less meaningful, than it appears at first sight

Inequity in cardiovascular care in the English National Health Service (NHS): a scoping review of the literature

There is a general understanding that socioeconomically disadvantaged people are also disadvantaged with respect to their access to NHS care. Insofar as considerable NHS funding has been targeted at deprived areas, it is important to better understand whether and why socioeconomic variations in access and utilisation exist. Exploring this question with reference to cardiovascular care, our aims were to synthesise and evaluate evidence relating to access to and/or use of English NHS services around (i) different points on the care pathway (i.e. presentation, primary management and specialist management) and (ii) different dimensions of inequality (socioeconomic, age- and gender-related, ethnic or geographical). Restricting our search period from 2004 to 2016, we were concerned to examine whether, compared to earlier research, there has been a change in the focus of research examining inequalities in cardiac care and whether the pro-rich bias reported in the late 1990s and early 2000s still applies today. We conducted a scoping study drawing on Arksey &amp; O'Malley's framework. A total of 174 studies were included in the review and appraised for methodological quality. Although, in the past decade, there has been a shift in research focus away from gender and age inequalities in access/use and towards socioeconomic status and ethnicity, evidence that deprived people are less likely to access and use cardiovascular care is very contradictory. Patterns of use appear to vary by ethnicity; South Asian populations enjoying higher access, black populations lower. By contrast, female gender and older age are consistently associated with inequity in cardiovascular care. The degree of geographical variation in access/use is also striking. Finally, evidence of inequality increases with stage on the care pathway, which may indicate that barriers to access arise from the way in which health professionals are adjudicating health needs rather than a failure to seek help in the first place.</p

The association between suicidal behavior, attentional control, and frontal asymmetry

It can be difficult to identify those at risk of suicide because suicidal thoughts are often internalized and not shared with others. Yet to prevent suicide attempts it is crucial to identify suicidal thoughts and actions at an early stage. Past studies have suggested that deficits in attentional control are associated with suicide, with the argument that individuals are unable to inhibit negative thoughts and direct resources away from negative information. The current study aimed to investigate the association of suicidal behavior with neurological and behavioral markers, measuring attentional bias and inhibition in two Stroop tasks. Fifty-four participants responded to the color of color words in a standard Stroop task and the color of positive, negative, and neutral words in an emotional Stroop task. Electroencephalographic (EEG) activity was recorded from frontal areas during each task and at resting. Participants were separated into a low-risk and high-risk group according to their self-20 reported suicidal behavior. Participants in the high-risk group showed slower response times in the color Stroop and reduced accuracy to incongruent trials, but faster response times in the emotional Stroop task. Response times to the word “suicide” were significantly slower for the high-risk group. This indicates an attentional bias towards specific negative stimuli and difficulties inhibiting information for those with high levels of suicidal behavior. In the emotional Stroop task the high-risk group showed reduced activity in leftward frontal areas, suggesting limitations in the ability to regulate emotional processing via the left frontal regions. The findings support the argument that deficits in attentional control are related to suicidal behavior. The research also suggests that under certain conditions frontal asymmetry may be associated with suicidal behavior

Investigating the dynamics of resilience and greenhouse gas performance of pastoral cattle systems in southern Ethiopia

Context: Pastoral and agro-pastoral (PAP) systems in East Africa face a range of challenges including increased climate variability. Various measures have been proposed to improve the resilience of pastoral/agro-pastoral (PAP) systems to drought. However, identifying the most effective measure for a given system and location is complicated, and tools are required to appraise measures on a consistent basis.Objective: This paper develops a model of a PAP system and uses it to assess the effects of four measures (Index-based livestock insurance, IBLI; Commercial destocking with an early warning system, EWS; Rangeland restoration, RR; Fodder planting, FP) on the resilience of the PAP system. It also quantifies the greenhouse gas (GHG) effects of the measures, thereby identifying potential trade-offs and synergies between the policy objectives of resilience and climate smart agriculture (CSA).Methods: A dynamic model of the Borena pastoral cattle system was developed to undertake the analysis. At its core is a herd model that calculates the changes in cattle population over time. Feed availability and drought occurrence affect fertility and mortality rates, which in turn determine the population and (meat and milk) production. A suite of indicators covering the three dimensions of CSA (increasing productivity, enhancing resilience and reducing GHG emissions) were developed, and used to compare the situation with and without measures.Results and discussions: Destocking with an early warning system provides the biggest increases (relative to the no measure situation) in production and profit, due to the way it changes the herd size and structure. It maintains a larger herd than any of the other measures, and a greater proportion of the herd are adult females. Fodder planting and rangeland restoration provide moderate increases in production and profit. Index-based livestock insurance provides a moderate increase in protein production, but has no effect on profit, as it is designed to reduce risk rather than increase productivity or profit, at least in the short term.All of the measures increase the total emissions relative to the no measure scenario. In terms of the three dimensions of climate-smart agriculture, IBLI leads to some improvements in productivity and resilience but leads to large increases in total emissions, and modest increases in emissions intensity (EI). EWS leads to large increases in productivity and resilience. However, it also leads to large increases in total emissions and a mixed effect on EI. FP and RR improve productivity and increase total emissions, while having little effect on EI or resilience.Significance: This paper illustrates the way in which systems dynamic model can be used to appraise measures designed to improve resilience. The result identify potential synergies and tensions between the goals of resilience and climate smart agriculture, and raises the question of whether fully climate-smart goals are viable in these systems