17 research outputs found
Survival analysis of time to SARS-CoV-2 PCR negativisation to optimise PCR prescription in health workers: the Henares COVID-19 healthcare workers cohort study.
Objectives Reverse transcriptase PCR (RT-PCR) is considered the gold standard in diagnosing COVID-19. Infected healthcare workers do not go back to work until RT-PCR has demonstrated that the virus is no longer present in the upper respiratory tract. The aim of this study is to determine the most efficient time to perform RT-PCR prior to healthcare workersâ reincorporation.
Materials and methods This is a cohort study of healthcare workers with RT-PCR-confirmed COVID-19. Data were collected using the medical charts of healthcare workers and completed with a telephone interview. Kaplan-Meier curves were used to determine the influence of several variables on the time to RT-PCR negativisation. The impact of the variables on survival was assessed using the Breslow test. A Cox regression model was developed including the associated variables.
Results 159 subjects with a positive RT-PCR out of 374 workers with suspected COVID-19 were included. The median time to negativisation was 25 days from symptom onset (IQR 20â35 days). Presence of IgG, dyspnoea, cough and throat pain were associated with significant longer time to negativisation. Cox logistic regression was used to adjust for confounding variables. Only dyspnoea and cough remained in the model as significant determinants of prolonged negativisation time. Adjusted HRs were 0.68 (0.48â096) for dyspnoea and 0.61 (0.42â0.88) for dry cough.
Conclusions RT-PCR during the first 3 weeks leads to a high percentage of positive results. In the presence of respiratory symptoms, negativisation took nearly 1 week more. Those who developed antibodies needed longer time to negativisate.pre-print396 K
Clonal chromosomal mosaicism and loss of chromosome Y in elderly men increase vulnerability for SARS-CoV-2
The pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2, COVID-19) had an estimated overall case fatality ratio of 1.38% (pre-vaccination), being 53% higher in males and increasing exponentially with age. Among 9578 individuals diagnosed with COVID-19 in the SCOURGE study, we found 133 cases (1.42%) with detectable clonal mosaicism for chromosome alterations (mCA) and 226 males (5.08%) with acquired loss of chromosome Y (LOY). Individuals with clonal mosaic events (mCA and/or LOY) showed a 54% increase in the risk of COVID-19 lethality. LOY is associated with transcriptomic biomarkers of immune dysfunction, pro-coagulation activity and cardiovascular risk. Interferon-induced genes involved in the initial immune response to SARS-CoV-2 are also down-regulated in LOY. Thus, mCA and LOY underlie at least part of the sex-biased severity and mortality of COVID-19 in aging patients. Given its potential therapeutic and prognostic relevance, evaluation of clonal mosaicism should be implemented as biomarker of COVID-19 severity in elderly people. Among 9578 individuals diagnosed with COVID-19 in the SCOURGE study, individuals with clonal mosaic events (clonal mosaicism for chromosome alterations and/or loss of chromosome Y) showed an increased risk of COVID-19 lethality
Evolving trends in the management of acute appendicitis during COVID-19 waves. The ACIE appy II study
Background: In 2020, ACIE Appy study showed that COVID-19 pandemic heavily affected the management of patients with acute appendicitis (AA) worldwide, with an increased rate of non-operative management (NOM) strategies and a trend toward open surgery due to concern of virus transmission by laparoscopy and controversial recommendations on this issue. The aim of this study was to survey again the same group of surgeons to assess if any difference in management attitudes of AA had occurred in the later stages of the outbreak.
Methods: From August 15 to September 30, 2021, an online questionnaire was sent to all 709 participants of the ACIE Appy study. The questionnaire included questions on personal protective equipment (PPE), local policies and screening for SARS-CoV-2 infection, NOM, surgical approach and disease presentations in 2021. The results were compared with the results from the previous study.
Results: A total of 476 answers were collected (response rate 67.1%). Screening policies were significatively improved with most patients screened regardless of symptoms (89.5% vs. 37.4%) with PCR and antigenic test as the preferred test (74.1% vs. 26.3%). More patients tested positive before surgery and commercial systems were the preferred ones to filter smoke plumes during laparoscopy. Laparoscopic appendicectomy was the first option in the treatment of AA, with a declined use of NOM.
Conclusion: Management of AA has improved in the last waves of pandemic. Increased evidence regarding SARS-COV-2 infection along with a timely healthcare systems response has been translated into tailored attitudes and a better care for patients with AA worldwide
Outcomes from elective colorectal cancer surgery during the SARS-CoV-2 pandemic
This study aimed to describe the change in surgical practice and the impact of SARS-CoV-2 on mortality after surgical resection of colorectal cancer during the initial phases of the SARS-CoV-2 pandemic
Aprendizajes y prĂĄcticas educativas en las actuales condiciones de Ă©poca: COVID-19
âEsta obra colectiva es el resultado de una convocatoria a docentes, investigadores y profesionales del campo pedagĂłgico a visibilizar procesos investigativos y prĂĄcticas educativas situadas en el marco de COVI-19. La misma se inscribe en el trabajo llevado a cabo por el equipo de InvestigaciĂłn responsable del Proyecto âSentidos y significados acerca de aprender en las actuales condiciones de Ă©poca: un estudio con docentes y estudiantes de la educaciĂłn secundarias en la ciudad de CĂłrdobaâ de la Facultad de FilosofĂa y Humanidades. Universidad Nacional de CĂłrdoba.
El momento excepcional que estamos atravesando, pero que tambiĂ©n nos atraviesa, ha modificado la percepciĂłn temporal a punto tal que habitamos un tiempo acelerado y angustiante que nos exige la producciĂłn de conocimiento provisorio. La presente publicaciĂłn surge como un espacio para detenernos a documentar lo que nos acontece y, a su vez, como oportunidad para atesorar y resguardar las experiencias educativas que hemos construido, inventado y reinventando en este contexto. En ella encontrarĂĄn pluralidad de voces acerca de enseñar y aprender durante la pandemia. Este texto es una pausa para reflexionar sobre el hacer y las prĂĄcticas educativas por venirâ.Fil: Beltramino, Lucia (comp.). Universidad Nacional de CĂłrdoba. Facultad de FilosofĂa y Humanidades. Escuela de ArchivologĂa; Argentina
Proyecto, investigación e innovación en urbanismo, arquitectura y diseño industrial
Actas de congresoLas VII Jornadas de InvestigaciĂłn âEncuentro y ReflexiĂłnâ y I Jornadas de InvestigaciĂłn de becarios y doctorandos. Proyecto, investigaciĂłn e innovaciĂłn en Urbanismo, Arquitectura y Diseño Industrial se centraron en cuatro ejes: el proyecto; la dimensiĂłn tecnolĂłgica y la gestiĂłn; la dimensiĂłn social y cultural y la enseñanza en Arquitectura, Urbanismo y Diseño Industrial, sustentados en las lĂneas prioritarias de investigaciĂłn definidas epistemolĂłgicamente en el Consejo Asesor de Ciencia y TecnologĂa de esta Universidad Nacional de CĂłrdoba.
Con el objetivo de afianzar continuidad, formaciĂłn y transferencia de mĂ©todos, metodologĂa y recursos se incorporĂł becarios y doctorandos de los Institutos de investigaciĂłn.
La ComisiĂłn Honoraria la integraron las tres Secretarias de InvestigaciĂłn de la Facultad, arquitectas Marta Polo, quien fundĂł y MarĂa del Carmen Franchello y Nora GutiĂ©rrez Crespo quienes continuaron la tradiciĂłn de la buena prĂĄctica del debate en la cotidianeidad de la propia Facultad.
Los textos que conforman las VII Jornadas son los avances y resultados de las investigaciones realizadas en el bienio 2016-2018.Fil: Novello, MarĂa Alejandra. Universidad Nacional de CĂłrdoba. Facultad de Arquitectura, Urbanismo y Diseño; ArgentinaFil: Repiso, Luciana. Universidad Nacional de CĂłrdoba. Facultad de Arquitectura, Urbanismo y Diseño; ArgentinaFil: Mir, Guillermo. Universidad Nacional de CĂłrdoba. Facultad de Arquitectura, Urbanismo y Diseño; ArgentinaFil: Brizuela, Natalia. Universidad Nacional de CĂłrdoba. Facultad de Arquitectura, Urbanismo y Diseño; ArgentinaFil: Herrera, Fernanda. Universidad Nacional de CĂłrdoba. Facultad de Arquitectura, Urbanismo y Diseño; ArgentinaFil: PerĂes, Lucas. Universidad Nacional de CĂłrdoba. Facultad de Arquitectura, Urbanismo y Diseño; ArgentinaFil: Romo, Claudia. Universidad Nacional de CĂłrdoba. Facultad de Arquitectura, Urbanismo y Diseño; ArgentinaFil: Gordillo, Natalia. Universidad Nacional de CĂłrdoba. Facultad de Arquitectura, Urbanismo y Diseño; ArgentinaFil: Andrade, Elena Beatriz. Universidad Nacional de CĂłrdoba. Facultad de Arquitectura, Urbanismo y Diseño; Argentin
I Congresso Ibero-Americano de Bibliotecas Escolares
Actas de la primera ediciĂłn del I Congreso Iberoamericano de Bibliotecas Escolares, CIBES 2015, organizado por la Universidad Carlos III de Madrid (España), la Universidad Estatal Paulista (Brasil) y el Ayuntamiento de Getafe (España). Celebrado: 21 - 23 de octubre de 2015 en la Universidad Estatal Paulista (MarĂlia) y 26 - 28 de octubre de 2015 en la Universidad Carlos III de Madrid (Getafe)Universidad Carlos III de Madrid (España)Universidad Estatal Paulista (Brasil)Ayuntamiento de Getafe (España)Dimensiones y visiones de la biblioteca escolar en una EducaciĂłn por competencias: la
necesidad de una polĂtica estratĂ©gica / Miguel Ăngel Marzal. -- Getafe ciudad educadora,
lectora y escritora: Bibliotecas escolares / Lourdes Muñoz Santiuste. -- Presente y
futuro: biblioteca escolar-CREA y proyectos interdisciplinares / Rosa PiquĂn. -- Cultura
en informaciĂłn: un reto esencial de la biblioteca escolar / MĂłnica BarĂł. -- Bibliotecas
escolares de Galicia: un mundo de oportunidades a favor de la EducaciĂłn / Cristina Novoa.
-- 10 años de la Red de Bibliotecas Escolares de Extremadura (REBEX) / Casildo MacĂas
Pereira. -- Biblioteca Escolar y uso Ă©tico de la informaciĂłn para una Cultura de Paz / Ana
Barrero TĂscar. -- DinamizaciĂłn de la Biblioteca Escolar Plumita durante el curso escolar
2014/15 / MarĂa Antonia Cano Cañada. -- Experiencia de la creaciĂłn de una biblioteca
escolar / Susana Santos MartĂn. -- Grupo cooperativo Bibliotecas escolares en Red-Albacete
/ José Manuel Garrido Argandoña y Eva Leal Scasso. -- La BCREA "Juan Leiva". El fomento de
la lectura desde la web social / Andrés Pulido Villar. -- Proceso de implantación de una
herramienta de autoevaluaciĂłn en la red de bibliotecas escolares de Extremadura (REBEX) /
Casildo MacĂas Pereira. -- La biblioteca escolar: abriendo fronteras / Lorena VerĂłnica
Cabrera Orellana. -- O programa RBE e a avaliaçao das bibliotecas escolares: melhoria,
desenvolvimiento e innovaçao / Elsa Conde. -- Profesional de BiblioteconomĂa y
DocumentaciĂłn: esencial en la plantilla de la escuela / Pilar del Campo Puerta. -- Una
mirada activa al proceso educativo desde la biblioteca escolar / MarĂa JesĂșs Fontela
FernĂĄndez . -- Con otra mirada "La ilustraciĂłn como vehĂculo de comunicaciĂłn y aprendizaje
en las bibliotecas escolares" / Pablo Jurado SĂĄnchez-GalĂĄn. -- Fingertips. Recriar a
biblioteca escolar na sala de aula / Rui Alfonso Mateus. -- Hablemos de libros. CĂłmo
transformar una clase de literatura en una comunidad de interpretaciĂłn de textos /
Francisco CĂ©sar DĂaz Rey. -- InclusiĂłn social de familias inmigrantes a travĂ©s de un
programa de aprendizaje de la lengua castellana / Ana Carmen Tolino FernĂĄndez-Henarejos.
-- O desenvolvimento de atividades de mediação de leitura em biblioteca escolar: o caso da
biblioteca da Escola Sesc de Ensino MĂ©dio / Vagner Amaro. -- La biblioteca escolar.
Proceso de enseñanza-aprendizaje de padres a hijos / Ana Carmen Tolino Fernåndez-
Henarejos. -- Leo con y para los demĂĄs / Ismael FernĂĄndez FernĂĄndez, Ana MarĂa Moreno
Vicente y Ana Beatriz Vicente PĂ©rez. -- Nanas y arrullo. PoesĂa a la deriva / Bernardo
Fuentes Navarrete y Carlos GarcĂa-Romeral PĂ©rez. -- GestiĂłn y evaluaciĂłn de servicios
bibliotecarios para personas con dislexia: una biblioteca escolar inclusiva desde una
perspectiva internacional / Carmen Jorge GarcĂa-Reyes. -- Sueños lectores compartidos
hechos realidad: la biblioteca escolar del C.E.I.P-S.E.S-A.A âLA PAZâ de Albacete / Ana
Rosa Cabañero Tobarra, Juan Manuel HerrĂĄez, Eva Leal Scasso, MarĂa MarĂn SĂĄnchez, Ana
BelĂ©n Medrano MartĂnez y MarĂa JosĂ© Nortes RuipĂ©rez. -- El programa biblioteca escuela en
Civican. La literatura como elemento motivador para la alfabetizaciĂłn informacional /
Villar Arellano Yanguas. -- La competencia digital en el diseño curricular: desde la
biblioteca al aula / Felicidad Campal GarcĂa. -- O deselvomimento da pesquisa escolar por
meio da competĂȘncia em informaçao / Luciane de FĂĄtima Cavalcante Beckman y Marta Leandro
da Mata. -- Proyecto escolar de investigación documental "Te pillé leyendo" / José Manuel
Garrido Argandoña. -- Aprender com a Biblioteca Escolar: formar para as literacias / Paula
Correia y Isabel Mendinhos. -- SucediĂł en el siglo XX / MarĂa Antonia Becerra MontalbĂĄn,
Ăngel BernabĂ© Muñoz y SofĂa Vaz Romero. -- El Club de lectura en la nube / BelĂ©n Benito
BlĂĄzquez y Ana OrdĂĄs GarcĂa. -- Promover a leitura e a escrita na era digital:
prĂĄcticas nas bibliotecas escolares / MarĂa Raquel Ramos. -- A biblioteca escolar e o
desafĂo da interculturalidade: o projeto Ser + cidadao / MarĂa da Conceição TomĂ©. --
Cuando la competencia digital encontrĂł a la alfabetizaciĂłn informacional o Mucho ruido y
pocas nueces / Felicidad Campal GarcĂa. -- Hora de ler, un programa para el fomento de la
lectura en contexto educativo / Cristina Novoa. -- HĂĄbitos de lectura para las
competencias en informaciĂłn y alfabetizaciĂłn en informaciĂłn en bibliotecas escolares de
Puerto Rico / Karen Denise Centeno Casillas. -- Repositorios digitales en las bibliotecas
escolares andaluzas: situaciĂłn, modelos y herramientas para su creaciĂłn / Dolores Olmos
Olmos y Andrés Pulido Villar. -- Trabajando las competencias clave con las aventuras de
Mozarito en Extremadura / MarĂa Teresa Carballosa GonzĂĄlez y MarĂa Esther Nieto Vidal. --
AnĂĄlisis de modelos de evaluaciĂłn de la web de la biblioteca escolar / RaĂșl Cremades
GarcĂa. -- EmociĂłnate con las historias: El bosque de las emociones e historias con mucho
teatro / Esther Luis PĂ©rez y Ana MarĂa Peromingo FernĂĄndez. -- Biblioteca escolar de
innovaciĂłn y continuaciĂłn / E. MarĂa Guerrero Palacios y Silvia Mora RamĂrez. -- Uso de
estĂĄndares y licencias para la creaciĂłn y difusiĂłn de contenidos en las bibliotecas
escolares / José Luis Barreiro Cebey. -- La biblioteca escolar digital móvil / Javier
FernĂĄndez Delgado. -- Uso de aplicaciones mĂłviles para el desarrollo de
la competencia lingĂŒĂstica. Proyecto Hansel App Gretel / Dolores Olmos Olmos. -- A memĂłria
e a mediação segundo Vigotski / Leda Maria AraĂșjo, Patricia Celia Santana, Sueli Bortolin
y Leticia Gorri Molina. -- Bibliotecas escolares como tema de estudo dos alunos de
graduação em blioteconomia do Instituto de Ensino Superior da FUNLEC: estado da arte /
Tiago Pereira Nocera y Rodrigo Pereira. -- AçÔes de mediação da leitura e da informação
em bibliotecas escolares: um olhar sobre as bibliotecas dos Colégios de Aplicação /
Tatyanne Christina Gonçalves Ferreira Valdez y Alberto Calil JĂșnior. -- Mediação
pedagĂłgica numa biblioteca de escola pĂșblica em Londrina / Rovilson JosĂ© da Silva, Teba
Silva Yllana y Sueli Bortolin. -- Utilização de categorias por cores em sistema de
biblioteca voltado ao pĂșblico infanto-juvenil / Liliana Giusti Serra. -- Atividades de
ensino dos atos de leitura com crianças em risco social / Adriana Naomi Fukushima da Silva
y Dagoberto Buim Arena. -- Biblioteca escolar: espaço de significados entre
alunos, professores e bibliotecĂĄrios / Rodrigo Barbosa Paulo, Marisa Xavier, Helen Castro
Casarin y Creuza Barbaroto. -- A Biblioteca Escolar no Contexto da Legislação e
do Processo Educativo / Eliane Lourdes da Silva Moro, Francisca Rosaline Leite Mota y
Raimundo Martins de Lima. -- O jornal impresso como fonte de informação: a importùncia da
formação de leitores crĂticos / Mariana PĂcaro Cerigatto. -- Bibliotecas escolares no
estado do Rio Grande do Sul: a trajetĂłria de realização dos fĂłruns gaĂșchos pela melhoria
das bibliotecas escolares / Eliane Lourdes da Silva Moro y Lizandra Brasil Estabel. -- O
acesso Ă informação dos usuĂĄrios surdos na biblioteca escolar / AndrĂ© LuĂs OnĂłrio
Coneglian y Mayara Melo Santana. -- Aprendizagem coletiva de bibliotecĂĄrios e a
competĂȘncia de pesquisa dos docentes: o caso do Instituto Federal do EspĂrito Santo /
Maristela Almeida Mercandeli Rodrigues y Beatriz Quiroz Villardi. -- Biblioteca escolar:
atores, parĂąmetros e competĂȘncias / Mavi Galante Mancera DallÂŽAcqua Carvalho y Claudio
Marcondes de Castro Filho. -- Estratégias de aprendizagem de escrita no
Ensino Fundamental II / Ărika Christina Kohle. -- BebĂȘs e livros: leitura nas bebetecas.
Kenia Adriana de Aquino Modesto Silva, Juliane Francischeti Martins Motoyama y Renata
Junqueira de Souza. -- Pråticas alternativas para organização de acervos nos espaços de
leitura em ambientes escolares / Luciana Souza Gracioso, Ariovaldo Alves,
DĂ©bora Nascimento, Suelen Redondo, Tainara Torika Kiri de Castro, Elizabete Angelon y
Eduardo Barbosa. -- ReflexÔes sobre a modelagem e criação de uma Rede Virtual de Leitores
para Bibliotecas Escolares / Carla Floriana Martins y Raoni Guerra RajĂŁo. -- Biblioteca
escolar: espaço de formação leitora? / Silvana Ferreira de Souza Balsan y Renata
Junqueira de Souza. -- âSe a Biblioteca Escolar Ă© minha mĂŁe, o Google Ă© meu paiâ:
representaçÔes da relação entre Biblioteca Escolar e Google no imaginårio de
alunos do ensino técnico / Adriana Bogliolo Sirihal-Duarte, Maria L. Amorim Antunes y
Raquel Miranda Vilela Paiva. -- Desafios e propostas para a universalização das
bibliotecas escolares no Brasil e na Espanha / Rodrigo Pereira, Daniela Spudeit y Fernanda
de Sales. -- Bibliotecårio educador: possibilidades de atuação no contexto da biblioteca
escolar / André Carlos da Silva, Valéria Martin Valls y Mariana de Paula Silva. -- Uma ONG
para Bibliotecas Escolares : estratégia para ampliar a igualdade e capacidade de acesso
e uso da informação e educação escolar de qualidade / Suelen Camilo Ferreira y Luciana de
Souza Gracioso. -- O aluno com deficĂȘncia: o papel do bibliotecĂĄrio na disponibilidade de
recursos acessĂveis na biblioteca escolar / Adriano de Sales Coelho, Rosilene de Melo
Oliveira y Marcos Pastana Santos. -- Biblioteca digital virtual e o uso do tablete: uma
possibilidade de construção de novas pråticas de leitura na escola / Barbara Cibelli da
Silva Monteagudo y Dagoberto Buim Arena. -- A importùncia da biblioteca na educação de
crianças de 0 a 3 anos / Yngrid Karolline Mendonça Costa y Cyntia Graziella Guizelim
SimÔes Girotto. -- Comportamento Informacional de adolescentes: a relação com bibliotecas
e escolas / Nelson Sebastian Silva-Jerez y Helen de Castro S. Casarin
Reducing the environmental impact of surgery on a global scale: systematic review and co-prioritization with healthcare workers in 132 countries
Abstract
Background
Healthcare cannot achieve net-zero carbon without addressing operating theatres. The aim of this study was to prioritize feasible interventions to reduce the environmental impact of operating theatres.
Methods
This study adopted a four-phase Delphi consensus co-prioritization methodology. In phase 1, a systematic review of published interventions and global consultation of perioperative healthcare professionals were used to longlist interventions. In phase 2, iterative thematic analysis consolidated comparable interventions into a shortlist. In phase 3, the shortlist was co-prioritized based on patient and clinician views on acceptability, feasibility, and safety. In phase 4, ranked lists of interventions were presented by their relevance to high-income countries and lowâmiddle-income countries.
Results
In phase 1, 43 interventions were identified, which had low uptake in practice according to 3042 professionals globally. In phase 2, a shortlist of 15 intervention domains was generated. In phase 3, interventions were deemed acceptable for more than 90 per cent of patients except for reducing general anaesthesia (84 per cent) and re-sterilization of âsingle-useâ consumables (86 per cent). In phase 4, the top three shortlisted interventions for high-income countries were: introducing recycling; reducing use of anaesthetic gases; and appropriate clinical waste processing. In phase 4, the top three shortlisted interventions for lowâmiddle-income countries were: introducing reusable surgical devices; reducing use of consumables; and reducing the use of general anaesthesia.
Conclusion
This is a step toward environmentally sustainable operating environments with actionable interventions applicable to both highâ and lowâmiddleâincome countries
Unprecedented increase of West Nile virus neuroinvasive disease, Spain, summer 2020.
Cases of West Nile neuroinvasive disease (WNND) in Spain increased in summer 2020. Here we report on this increase and the local, regional and national public health measures taken in response. We analysed data from regional surveillance networks and the National Epidemiological Surveillance Network, both for human and animal West Nile virus (WNV) infection. During the 2020 season, a total of 77 human cases of WNV infection (median age 65 years; 60% males) were detected in the south-west of Spain; 72 (94%) of these cases developed WNND, presenting as meningoencephalitis, seven of which were fatal. In the previous two decades, only six human cases of WNND were detected in Spain. Reduced activities for vector control this season, together with other factors, might have contributed to the massive increase. Public health measures including vector control, campaigns to raise awareness among physicians and the general population, and interventions to ensure the safety of donations of blood products, organs, cells and tissues were effective to reduce transmission. Going forward, maintenance of vector control activities and an update of the vector-borne diseases response plan in Spain is needed.S