999 research outputs found
Complexity biomechanics: a case study of dragonfly wing design from constituting composite material to higher structural levels.
Presenting a novel framework for sustainable and regenerative design and development is a fundamental future need. Here we argue that a new framework, referred to as complexity biomechanics, which can be used for holistic analysis and understanding of natural mechanical systems, is key to fulfilling this need. We also present a roadmap for the design and development of intelligent and complex engineering materials, mechanisms, structures, systems, and processes capable of automatic adaptation and self-organization in response to ever-changing environments. We apply complexity biomechanics to elucidate how the different structural components of a complex biological system as dragonfly wings, from ultrastructure of the cuticle, the constituting bio-composite material of the wing, to higher structural levels, collaboratively contribute to the functionality of the entire wing system. This framework not only proposes a paradigm shift in understanding and drawing inspiration from natural systems but also holds potential applications in various domains, including materials science and engineering, biomechanics, biomimetics, bionics, and engineering biology. [Abstract copyright: © 2024 The Author(s).
Beam test calibration of the balloon-borne imaging calorimeter for the CREAM experiment
CREAM (Cosmic Ray Energetics And Mass) is a multi-flight balloon mission
designed to collect direct data on the elemental composition and individual
energy spectra of cosmic rays. Two instrument suites have been built to be
flown alternately on a yearly base. The tungsten/Sci-Fi imaging calorimeter for
the second flight, scheduled for December 2005, was calibrated with electron
and proton beams at CERN. A calibration procedure based on the study of the
longitudinal shower profile is described and preliminary results of the beam
test are presented.Comment: 4 pages, 4 figures. To be published in the Proceedings of 29th
International Cosmic Ray Conference (ICRC 2005), Pune, India, August 3-10,
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Next generation sequencing has lower sequence coverage and poorer SNP-detection capability in the regulatory regions
The rapid development of next generation sequencing (NGS) technology provides a new chance to extend the scale and resolution of genomic research. How to efficiently map millions of short reads to the reference genome and how to make accurate SNP calls are two major challenges in taking full advantage of NGS. In this article, we reviewed the current software tools for mapping and SNP calling, and evaluated their performance on samples from The Cancer Genome Atlas (TCGA) project. We found that BWA and Bowtie are better than the other alignment tools in comprehensive performance for Illumina platform, while NovoalignCS showed the best overall performance for SOLiD. Furthermore, we showed that next-generation sequencing platform has significantly lower coverage and poorer SNP-calling performance in the CpG islands, promoter and 5′-UTR regions of the genome. NGS experiments targeting for these regions should have higher sequencing depth than the normal genomic region
Search for Neutral Higgs Bosons of the Minimal Supersymmetric Standard Model in e+e- Interactions at \sqrt{s} = 189 GeV
A search for the lightest neutral scalar and neutral pseudoscalar Higgs
bosons in the Minimal Supersymmetric Standard Model is performed using 176.4
pb^-1 of integrated luminosity collected by L3 at a center-of-mass energy of
189 GeV. No signal is observed, and the data are consistent with the expected
Standard Model background. Lower limits on the masses of the lightest neutral
scalar and pseudoscalar Higgs bosons are given as a function of tan(beta).
Lower mass limits for tan(beta)>1 are set at the 95% confidence level to be m_h
> 77.1 GeV and m_A > 77.1 GeV
Search for Anomalous Couplings in the Higgs Sector at LEP
Anomalous couplings of the Higgs boson are searched for through the processes
e^+ e^- -> H gamma, e^+ e^- -> e^+ e^- H and e^+ e^- -> HZ. The mass range 70
GeV < m_H < 190 GeV is explored using 602 pb^-1 of integrated luminosity
collected with the L3 detector at LEP at centre-of-mass energies
sqrt(s)=189-209 GeV. The Higgs decay channels H -> ffbar, H -> gamma gamma, H
-> Z\gamma and H -> WW^(*) are considered and no evidence is found for
anomalous Higgs production or decay. Limits on the anomalous couplings d, db,
Delta(g1z), Delta(kappa_gamma) and xi^2 are derived as well as limits on the H
-> gamma gamma and H -> Z gamma decay rates
Measurement of W Polarisation at LEP
The three different helicity states of W bosons produced in the reaction e+
e- -> W+ W- -> l nu q q~ at LEP are studied using leptonic and hadronic W
decays. Data at centre-of-mass energies \sqrt s = 183-209 GeV are used to
measure the polarisation of W bosons, and its dependence on the W boson
production angle. The fraction of longitudinally polarised W bosons is measured
to be 0.218 \pm 0.027 \pm 0.016 where the first uncertainty is statistical and
the second systematic, in agreement with the Standard Model expectation
Study of the e+e- -> Ze+e- process at LEP
The cross section of the process e+e- -> Ze+e is measured with 0.7fb^-1 of
data collected with the L3 detector at LEP. Decays of the Z boson into quarks
and muons are considered at centre-of-mass energies ranging from 183GeV up to
209GeV. The measurements are found to agree with Standard Model predictions,
achieving a precision of about 10% for the hadronic channel
Search for Extra Dimensions in Boson and Fermion Pair Production in e+e- Interactions at LEP
Extra spatial dimensions are proposed by recent theories that postulate the
scale of gravity to be of the same order as the electroweak scale. A sizeable
interaction between gravitons and Standard Model particles is then predicted.
Effects of these new interactions in boson and fermion pair production are
searched for in the data sample collected at centre-of-mass energies above the
Z pole by the L3 detector at LEP. In addition, the direct production of a
graviton associated with a Z boson is investigated. No statistically
significant hints for the existence of these effects are found and lower limits
in excess of 1 TeV are derived on the scale of this new theory of gravity
Measurement of Bose-Einstein Correlations in e+e- -> W+W- at root(s)=189GeV
We investigate Bose-Einstein correlations (BEC) in W-pair production at
root(s)=189GeV using the L3 detector at LEP. We observe BEC between particles
from a single W decay in good agreement with those from a light-quark Z decay
sample. We investigate their possible existence between particles coming from
different W's. No evidence for such inter-W BEC is found
Search for Charged Higgs Bosons at LEP
A search for pair-produced charged Higgs bosons is performed with the L3
detector at LEP using data collected at centre-of-mass energies between 189 and
209GeV, corresponding to an integrated luminosity of 629.4/pb. Decays into a
charm and a strange quark or into a tau lepton and its neutrino are considered.
No significant excess is observed and lower limits on the mass of the charged
Higgs boson are derived at the 95% confidence level. They vary from 76.5 to
82.7GeV, as a function of the H->tv branching ratio
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