Association between vitamin D serum levels and clinical, laboratory, and parasitological parameters in patients with malaria from an endemic area of the Amazon

Marinha do Brasil. Centro de Instrução Almirante Braz de Aguiar. Belém, PA, Brasil / Universidade Federal do Pará. Núcleo de Medicina Tropical. Programa de Pós-Graduação em Doenças Tropicais. Belém, PA, Brasil.Universidade Federal do Pará. Núcleo de Medicina Tropical. Programa de Pós-Graduação em Doenças Tropicais. Belém, PA, Brasil.Ministério da Saúde. Secretaria de Vigilância em Saúde. Instituto Evandro Chagas. Laboratório de Ensaios Clínicos em Malária. Ananindeua, PA, Brasil / Universidade Estadual do Pará. Centro de Ciências Biológicas e da Saúde. Belém, PA, BrasilMinistério da Saúde. Secretaria de Vigilância em Saúde. Instituto Evandro Chagas. Laboratório de Ensaios Clínicos em Malária. Ananindeua, PA, Brasil / Universidade Federal do Pará. Centro Universitário do Estado do Pará. Belém, PA, BrasilUniversidade Estadual do Pará. Centro de Ciências Biológicas e da Saúde. Departamento de Saúde Integrada. Belém, PA, BrasilMinistério da Saúde. Secretaria de Vigilância em Saúde. Instituto Evandro Chagas. Ananindeua, PA, BrasilUniversidade Federal Fluminense. Programa de Pós-Graduação em Microbiologia e Parasitologia. Rio de Janeiro, RJ, Brasil.Universidade Federal de Viçosa. Programa de Pós-Graduação em Ciência da Nutrição. Viçosa, MG, BrasilEscola Superior da Amazônia. Pós-Graduação em Nutrição Esportiva e Estética. Belém, PA, BrasilBackground: Some studies have suggested the importance of vitamin D [25(OH)D] in malaria clinical practice. The prevalence of 25(OH)D deficiency in the Amazon population is not well known, and there are few studies in patients with malaria. This study aimed to evaluate 25(OH) D serum levels in patients with malaria and determine their relationships with epidemiological, clinical, laboratory, and parasitemia data. Methods: An analytical cross-sectional study of 123 patients with malaria and 122 individuals without malaria was performed in Itaituba, Pará, Brazil, from January 2018 to October 2019, by evaluating sociodemographic, clinical-epidemiological, parasitological, and laboratory data and adopting a 5% significance level. Parametric tests (Student's t-test), non-parametric tests (Mann-Whitney U), and Spearman’s correlation ([rs ], for non-parametric variables) were used according to the nature of the distribution of the variables. For the qualitative variables, Pearson's chi-square test, Fisher's exact test, and the G test were used. Spearman's correlation was used to compare the results of the 25(OH)D levels and blood counts performed among patients and the control group. Results: Malaria patients residing in a mining area had 25(OH)D serum levels that were significantly lower than those in the control group residing in the mining area, though both were within normal levels. Red blood cell counts had an inverse correlation with parasitemia (Plasmodium falciparum), and platelet levels had an inverse correlation with parasitemia (Plasmodium vivax). 25(OH)D deficiency was evidenced in Itaituba, in the state of Pará, which is an endemic area of malaria in the Amazon region

A revolução da Gabriela: o ano de 1977 em Portugal

Este trabalho apresenta os contextos da visionação, em 1977, da telenovela brasileira Gabriela, Cravo e Canela. Justifica-se a escolha do Corpus – dois diários (Diário de Notícias, Diário de Lisboa) e dois semanários (Expresso e O Jornal) explicitando-se as metodologias utilizadas na análise de imprensa. Faz-se o levantamento da agenda da telenovela Gabriela, Cravo e Canela nos quatro jornais seleccionados, confrontando-a com outra agenda, mais lata, da expansão e divulgação da indústria cultural brasileira em Portugal. Considera-se que o êxito desta telenovela antecipa a emergência de uma nova sociedade e estilos de vida, bem como uma outra imagem da mulher, centrados em novos valores, no consumo e nos media.This work describes the reception of the Brazilian telenovela Gabriela, Cravo e Canela in the year of 1977 in Portugal. The corpus is composed of two daily newspapers (Diário de Notícias, Diário de Lisboa) and two weekly papers (Expresso e O Jornal); The methods of analisys are presented. Afterwards the Agenda of the telenovela Gabriela... is identified in these newspapers and compared with the Agenda of Brasilian Cultural Industry in Portugal. The conclusion aims at a relation between the exhibition of the telenovela and the rise of a new society with new women’s models and life styles

Crystallization ages of Paleoproterozoic A-type granites of Carajás province, Amazon craton: Constraints from U-Pb geochronology of zircon and titanite

New U-Pb SHRIMP dating in zircon and titanite showed that the three large Paleoproterozoic A-type granite Suites and related granites from Carajás Province of the Amazon Craton (Brazil) were emplaced between 1880 Ma and 1857 Ma, with the main magmatic peak at 1880 Ma. Some particular ages not reported before have been identified: (i) ages of 1865 Ma to 1857 Ma in leucogranite facies of the Redenção and Bannach plutons, that are younger, were generated by independent magma pulses and are not cogenetic with the dominant ~1880 Ma old granites of the respective plutons; (ii) an age of 1732 ± 6 Ma obtained in the leucogranite facies of the Antônio Vicente pluton of the Velho Guilherme Suite that could represent a magmatic event in the Xingu Region not yet reported or, eventually, could correspond to an isolate hydrothermal event that allowed the growth of zircons. The more detailed geochronological data obtained in the Paleoproteozoic A-type granites of Carajás Province, added to the information available in the literature, demonstrate the relevance of the magmatic event at ~1880 Ma and indicate that the emplacement of those granites was done in about ~20 m.y. that means in a relatively short geological time. This 1880 Ma magmatic episode was also intense in other provinces of the Amazon Craton, where it is linked mostly to the formation of the Uatumã Silicic Large Igneous Province. This event was mostly extensional and isalso registered in several cratons worldwide demonstrating its relevance in the tectonic evolution of Proterozoic continents