Mortalidad bovina en la altillanura del Vichada

Recoge en forma resumida, los aspectos más relevantes encontrados por los autores, en una investigación realizada en la altillanura del Vichada, entre Santa Rosalia y Puerto Carreño, en hatos con ganadería bovina extensiva-extractiva, denominada: diagnóstico y alternativas de control al problema de la mortalidad bovina en un área del Vichada. Los predios estudiados se ubicaron a un máximo de 10 km del río Meta, se tomarón muestras de suelos como también de forraje de sabana nativa, adicionalmente muestras de sangre de la población bovina. Los resultados mostraron suelos con altos contenidos de Al intercambiable, Fe y Mn, fuertemente ácidos y con bajos contenidos de P, K y Ca. El contenido promedio foliar de N estuvo entre 0.74 y 0.94 por ciento equivalente a un valor de 4.68 y 5.88 por ciento de proteína cruda. El porcentaje de Ca, P y Mg fué de 0.19 y 0.15 por ciento en materia seca, los elementos que presentaron amplia variabilidad fueron B, Fe, K, Mn, P y Cu. Los valores medios de proteína cruda, fibra detergente netro de degradabilidad insitu de la materia seca fueron 5.28 , 62 y 46 por ciento. El decrecimiento paulatino de las concentraciones de minerales en forrajes se sabana, manejadas bajo quema, es notorio a medida que aumenta la edad del rebrote. Los valores de química sérica y hematología muestran alta variación en fósforo sérico, hierro, globulina, hemoglobina corpuscular media y glóbulos blancos lo que manifiesta una leucopenia posiblemente ocasionada por recirculación de poblaciones virales, hematozoos, subnutrición o agentes inmunodepresores. Esta investigación contribuye a entender la situación como de origen multicausal, donde la subnutrición continuada, es quizá la causa principal que predispone un mayor riesgo de enfermedad, lento desarrollo corporal, ineficiencia reproductiva y mortalidadGanadería bovin

Prevalencia de Trypanosoma vivax en bovinos de Villavicencio por pruebas parasitológicas directas y por inmunofluorescencia indirecta.

Para determinar la prevalencia de tripanosomiasis bovina en Villavicencio, Colombia, empleando la técnica indirecta de anticuerpos fluorescentes, a manera de comparación se utilizaron los métodos parasitológicos directos. Se examinaron 500 bovinos mayores de un año en 50 fincas escogidas al azar. Se encontraron 47 reactores positivos o una prevalencia real entre 6.8 y 9.4 por ciento, utilizando la prueba de inmunofluorescencia indirecta. No se encontraron animales positivos al emplear los métodos parasitológicos directos (preparación en fresco, frotis delgado, gota gruesa, centrifugación en tubo capilar o técnica de Woo). Lo anterior indica la ausencia de correlación entre los procedimientos utilizados. Se comprueba que los métodos parasitológicos directos son solo de ayuda en los casos que cursan con parasitemias detectables. Se puede afirmar que el Tripanosoma vivax es endémico en esta región tropical de Colombia, destacándose la importancia de la tripanosomiasis como enfermedad inmunodepresora y los posibles efectos que puede tener sobre los programas de vacunación que se realicen en los bovinos de esta zona. Los reactores positivos pueden ser reservorios potenciales de tripanosomas, los cuales podrían transmitirse dada la presencia de algunos insectos vectoresGanado de leche-Ganadería lech

Global variations in diabetes mellitus based on fasting glucose and haemogloblin A1c

Fasting plasma glucose (FPG) and haemoglobin A1c (HbA1c) are both used to diagnose diabetes, but may identify different people as having diabetes. We used data from 117 population-based studies and quantified, in different world regions, the prevalence of diagnosed diabetes, and whether those who were previously undiagnosed and detected as having diabetes in survey screening had elevated FPG, HbA1c, or both. We developed prediction equations for estimating the probability that a person without previously diagnosed diabetes, and at a specific level of FPG, had elevated HbA1c, and vice versa. The age-standardised proportion of diabetes that was previously undiagnosed, and detected in survey screening, ranged from 30% in the high-income western region to 66% in south Asia. Among those with screen-detected diabetes with either test, the agestandardised proportion who had elevated levels of both FPG and HbA1c was 29-39% across regions; the remainder had discordant elevation of FPG or HbA1c. In most low- and middle-income regions, isolated elevated HbA1c more common than isolated elevated FPG. In these regions, the use of FPG alone may delay diabetes diagnosis and underestimate diabetes prevalence. Our prediction equations help allocate finite resources for measuring HbA1c to reduce the global gap in diabetes diagnosis and surveillance.peer-reviewe

Global variation in diabetes diagnosis and prevalence based on fasting glucose and hemoglobin A1c

International audienceAbstract Fasting plasma glucose (FPG) and hemoglobin A1c (HbA1c) are both used to diagnose diabetes, but these measurements can identify different people as having diabetes. We used data from 117 population-based studies and quantified, in different world regions, the prevalence of diagnosed diabetes, and whether those who were previously undiagnosed and detected as having diabetes in survey screening, had elevated FPG, HbA1c or both. We developed prediction equations for estimating the probability that a person without previously diagnosed diabetes, and at a specific level of FPG, had elevated HbA1c, and vice versa. The age-standardized proportion of diabetes that was previously undiagnosed and detected in survey screening ranged from 30% in the high-income western region to 66% in south Asia. Among those with screen-detected diabetes with either test, the age-standardized proportion who had elevated levels of both FPG and HbA1c was 29–39% across regions; the remainder had discordant elevation of FPG or HbA1c. In most low- and middle-income regions, isolated elevated HbA1c was more common than isolated elevated FPG. In these regions, the use of FPG alone may delay diabetes diagnosis and underestimate diabetes prevalence. Our prediction equations help allocate finite resources for measuring HbA1c to reduce the global shortfall in diabetes diagnosis and surveillance

Global variation in diabetes diagnosis and prevalence based on fasting glucose and hemoglobin A1c

: Fasting plasma glucose (FPG) and hemoglobin A1c (HbA1c) are both used to diagnose diabetes, but these measurements can identify different people as having diabetes. We used data from 117 population-based studies and quantified, in different world regions, the prevalence of diagnosed diabetes, and whether those who were previously undiagnosed and detected as having diabetes in survey screening, had elevated FPG, HbA1c or both. We developed prediction equations for estimating the probability that a person without previously diagnosed diabetes, and at a specific level of FPG, had elevated HbA1c, and vice versa. The age-standardized proportion of diabetes that was previously undiagnosed and detected in survey screening ranged from 30% in the high-income western region to 66% in south Asia. Among those with screen-detected diabetes with either test, the age-standardized proportion who had elevated levels of both FPG and HbA1c was 29-39% across regions; the remainder had discordant elevation of FPG or HbA1c. In most low- and middle-income regions, isolated elevated HbA1c was more common than isolated elevated FPG. In these regions, the use of FPG alone may delay diabetes diagnosis and underestimate diabetes prevalence. Our prediction equations help allocate finite resources for measuring HbA1c to reduce the global shortfall in diabetes diagnosis and surveillance

Diminishing benefits of urban living for children and adolescents’ growth and development

Optimal growth and development in childhood and adolescence is crucial for lifelong health and well-being1–6. Here we used data from 2,325 population-based studies, with measurements of height and weight from 71 million participants, to report the height and body-mass index (BMI) of children and adolescents aged 5–19 years on the basis of rural and urban place of residence in 200 countries and territories from 1990 to 2020. In 1990, children and adolescents residing in cities were taller than their rural counterparts in all but a few high-income countries. By 2020, the urban height advantage became smaller in most countries, and in many high-income western countries it reversed into a small urban-based disadvantage. The exception was for boys in most countries in sub-Saharan Africa and in some countries in Oceania, south Asia and the region of central Asia, Middle East and north Africa. In these countries, successive cohorts of boys from rural places either did not gain height or possibly became shorter, and hence fell further behind their urban peers. The difference between the age-standardized mean BMI of children in urban and rural areas was <1.1 kg m–2 in the vast majority of countries. Within this small range, BMI increased slightly more in cities than in rural areas, except in south Asia, sub-Saharan Africa and some countries in central and eastern Europe. Our results show that in much of the world, the growth and developmental advantages of living in cities have diminished in the twenty-first century, whereas in much of sub-Saharan Africa they have amplified

Effects of hospital facilities on patient outcomes after cancer surgery: an international, prospective, observational study

© 2022 The Author(s). Published by Elsevier Ltd. This is an Open Access article under the CC BY 4.0 licenseBackground: Early death after cancer surgery is higher in low-income and middle-income countries (LMICs) compared with in high-income countries, yet the impact of facility characteristics on early postoperative outcomes is unknown. The aim of this study was to examine the association between hospital infrastructure, resource availability, and processes on early outcomes after cancer surgery worldwide. Methods: A multimethods analysis was performed as part of the GlobalSurg 3 study—a multicentre, international, prospective cohort study of patients who had surgery for breast, colorectal, or gastric cancer. The primary outcomes were 30-day mortality and 30-day major complication rates. Potentially beneficial hospital facilities were identified by variable selection to select those associated with 30-day mortality. Adjusted outcomes were determined using generalised estimating equations to account for patient characteristics and country-income group, with population stratification by hospital. Findings: Between April 1, 2018, and April 23, 2019, facility-level data were collected for 9685 patients across 238 hospitals in 66 countries (91 hospitals in 20 high-income countries; 57 hospitals in 19 upper-middle-income countries; and 90 hospitals in 27 low-income to lower-middle-income countries). The availability of five hospital facilities was inversely associated with mortality: ultrasound, CT scanner, critical care unit, opioid analgesia, and oncologist. After adjustment for case-mix and country income group, hospitals with three or fewer of these facilities (62 hospitals, 1294 patients) had higher mortality compared with those with four or five (adjusted odds ratio [OR] 3·85 [95% CI 2·58–5·75]; p<0·0001), with excess mortality predominantly explained by a limited capacity to rescue following the development of major complications (63·0% vs 82·7%; OR 0·35 [0·23–0·53]; p<0·0001). Across LMICs, improvements in hospital facilities would prevent one to three deaths for every 100 patients undergoing surgery for cancer. Interpretation: Hospitals with higher levels of infrastructure and resources have better outcomes after cancer surgery, independent of country income. Without urgent strengthening of hospital infrastructure and resources, the reductions in cancer-associated mortality associated with improved access will not be realised. Funding: National Institute for Health and Care Research