1,176 research outputs found

    Heritage branding orientation: The case of Ach. Brito and the dynamics between corporate and product heritage brands

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    The notion of heritage branding orientation is introduced and explicated. Heritage branding orientation is designated as embracing both product and corporate brands and differs from corporate heritage brand orientation which has an explicit corporate focus. Empirical insights are drawn from an in-depth and longitudinal case study of Ach. Brito, a celebrated Portuguese manufacturer of soaps and toiletries. This study shows how, by the pursuance of a strategy derived from a heritage branding orientation Ach. Brito – after a prolonged period of decline – achieved a dramatic strategic turnaround. The findings reveal how institutional heritage can be a strategic resource via its adoption and activation at both the product and corporate levels. Moreover, the study showed how the bi-lateral interplay between product and corporate brand levels can be mutually reinforcing. In instrumental terms, the study shows how heritage can be activated and articulated in different ways. For instance, it can re-position both product and/or corporate brands; it can be meaningfully informed by product brand heritage and shape corporate heritage; and can be of strategic importance to both medium-sized and small enterprises

    The negotiating strategies determining coitus in stable heterosexual relationships

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    Heterosexual behaviour is a complex subject and one which is aggravated by confounding variables. Few studies have investigated the way in which one variable, namely coitus, is initiated and negotiated in stable marital relationships. As the HIV/AIDS pandemic spreads in sub-Saharan Africa, the subject of marital coitus becomes of increasing concern. This study tests a methodology of semi-structured interviews and diary-keeping techniques to investigate how the activity is initiated and negotiated. A research team monitored the study and evaluated the research techniques. The study concluded that the HIV/AIDS pandemic is affecting the initiation and negotiation of coitus between marital partners and that the partners wish to renegotiate the relationship, but the mechanisms for renegotiation are not at present available

    The meaning and challenge of voluntary counselling and testing (VCT) for counsellors: report of the Kenya Association of Professional Counsellors (KAPC) conference for sub-Saharan Africa

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    A large number of voluntary counselling and testing (VCT) sites are being opened in sub-Saharan Africa. The services provided by these sites are playing an increasingly important role in the prevention of HIV/AIDS. The sites offer many possibilities and it is crucial that they provide the optimum services for clients. Counselling is an integral part of these services, yet it receives little attention. Counsellors need to be consulted if the optimum services are to be provided, but they are rarely consulted for their professional opinion. Accordingly, the Kenya Association of Professional Counsellors (KAPC) organised a 3-day conference in September 2002 to provide counsellors, drawn from the sub-Saharan region, with a forum to identify VCT-related issues and discuss their implications. The main aim of the conference was for counsellors to arrive at a consensual position regarding HIV/AIDS and what improvements they thought could be made for the VCT services to clients. The counsellors identified the issues that they considered important and this paper presents those issues together with recommendations regarding improvements. Key words:Voluntary counselling and testing (VCT), conference report, sub-Saharan Africa. Les sens et le défi de la consultation et du dépistage volontaires (VCT) auprès des conseillers: le rapport de la conférence sur l'Afrique subsaharienne de l'Association de Conseillers Professionnels du Kenya (KAPC) RÉSUMÉ Un grand nombre de sites de consultation et de dépistage volontaires (VCT) sont mis en place en Afrique subsaharienne. Les services pourvus dans ces sites jouent un rôle encore plus important dans la prévention du VIH/SIDA. Les sites offrent beaucoup de possibilités et il est crucial qu'ils pourvoient des services les meilleurs aux clients. La consultation psychologique fait partie intégrante de ces services, malgré qu'elle reçoit très peu d'attention. Les conseillers psychologiques doivent être consultés si on veut optimiser les services fournis. Malheureusement, ils sont rarement consultés pour leur opinion professionnelle. En conséquence, l'Association des Conseillers Professionnels du Kenya (KAPC) a organisé une conférence sur 3 jours, en septembre 2002, afin de donner aux conseillers, venus de la région subsaharienne, un forum à l'intérieur duquel ils peuvent identifier les problèmes et discuter leurs implications. Le but principal de cette conférence était de permettre les conseillers à se mettre d'accord sur le VIH/SIDA d'une manière unanime et de proposer une amélioration de services de VCT mis à disposition des clients. Les conseillers ont identifié des problèmes considérés primordiaux. Cette communication présente ces problèmes et les recommandations liées aux améliorations proposées. Mots clés : Consultation et dépistage volontaires (VCT), rapport de conférence, Afrique subsaharienne. Sahara J Vol.1(3) 2004: 175-18

    Trypanosoma brucei gambiense group 1 is distinguished by a unique amino acid substitution in the HpHb receptor implicated in human serum resistance

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    Trypanosoma brucei rhodesiense (Tbr) and T. b. gambiense (Tbg), causative agents of Human African Trypanosomiasis (sleeping sickness) in Africa, have evolved alternative mechanisms of resisting the activity of trypanosome lytic factors (TLFs), components of innate immunity in human serum that protect against infection by other African trypanosomes. In Tbr, lytic activity is suppressed by the Tbr-specific serum-resistance associated (SRA) protein. The mechanism in Tbg is less well understood but has been hypothesized to involve altered activity and expression of haptoglobin haemoglobin receptor (HpHbR). HpHbR has been shown to facilitate internalization of TLF-1 in T.b. brucei (Tbb), a member of the T. brucei species complex that is susceptible to human serum. By evaluating the genetic variability of HpHbR in a comprehensive geographical and taxonomic context, we show that a single substitution that replaces leucine with serine at position 210 is conserved in the most widespread form of Tbg (Tbg group 1) and not found in related taxa, which are either human serum susceptible (Tbb) or known to resist lysis via an alternative mechanism (Tbr and Tbg group 2). We hypothesize that this single substitution contributes to reduced uptake of TLF and thus may play a key role in conferring serum resistance to Tbg group 1. In contrast, similarity in HpHbR sequence among isolates of Tbg group 2 and Tbb/Tbr provides further evidence that human serum resistance in Tbg group 2 is likely independent of HpHbR functio

    Absorção e distribuição do fósforo no algodoeiro em variedade resistente e suscetível a "murcha do algodoeiro"

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    In order to find out the effects of "wilding desease" on the absorption and distribution of phosphorus, cotton plants of the varieties IAC-12 (susceptible) and IAC - RM4 (susceptible) were cultivated in nutrient solution containing phosphorus, without phosphorus, incolulated or not by Fusarium Oxysporum f. vasinfactum. Soon as the plants presented disease symptoms they were transfered to nutrient solution containing 32P . The plants remained in the so ution during 48 hours. Determination of the phosphorus activity was carried out on the different parts of the plants. The presence of the fungus affected the distribution of phosphorus in both varities. The susceptible variety (IAC - RM4) affected by the desease showed a 45% reduction in the capacity of phosphorus absorption.Com objetivo de aquilatar a influência da "Murcha do algodoeiro" na absorção e distribuição do fósforo em var. suscetível e resistente, os autores cultivaram plantas de Gossypium hirsutum L. variedades IAC-12 e IAC-RM4 em solução nutritiva contendo fósforo, inoculados ou não com Fusarium oxysporum f. vasinfectum. Uma vez evidenciados os sintomas de "Murcha", as plantas foram expostas durante 48 horas a uma solução contendo fósforo marcado (32P). As amostras após conveniente tratamento foram expostas a um sistema de detecção e contagem (Geiger-Muller). Foram montados radioautógrafos. Os autores constataram que a presença do Fusarium afeta a distribuição do fósforo em ambas as variedades. A variedade suscetível (IAC-RM4) inoculada com o fungo perde a capacidade de absorver o fósforo em cêrca de 45%

    Demographic drivers of decline and recovery in an Afro-Palaearctic migratory bird population

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    Across Europe, rapid population declines are ongoing in many Afro-Palaearctic migratory bird species, but the development of appropriate conservation actions across such large migratory ranges is severely constrained by lack of understanding of the demographic drivers of these declines. By constructing regional integrated population models (IPMs) for one of the suite of migratory species that is declining in the south-east of Britain but increasing in the north-west, we show that, while annual population growth rates in both regions vary with adult survival, the divergent regional trajectories are primarily a consequence of differences in productivity. Between 1994 and 2012, annual survival and productivity rates ranged over similar levels in both regions, but high productivity rates were rarer in the declining south-east population and never coincided with high survival rates. By contrast, population growth in the north-west was fuelled by several years in which higher productivity coincided with high survival rates. Simulated population trajectories suggest that realistic improvements in productivity could have reversed the decline (i.e. recovery of the population index to ≥ 1) in the south-east. Consequently, actions to improve productivity on European breeding grounds are likely to be a more fruitful and achievable means of reversing migrant declines than actions to improve survival on breeding, passage or sub-Saharan wintering grounds

    Preventing “a virological Hiroshima”: Cold War press coverage of biological weapons disarmament

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    This article examines representations of biological weapons during a crucial period in the recent history of this form of warfare. The study draws on a corpus of newspaper articles from the US New York Times and the UK Times and Guardian written around the time of the negotiation period of the 1972 Biological Weapons Convention, the international treaty banning this form of warfare. We argue that a conventional discourse can be found wherein biological weapons are portrayed as morally offensive, yet highly effective and militarily attractive. Interwoven with this discourse, however, is a secondary register which depicts biological weapons as ineffective, unpredictable and of questionable value for the military. We finish with a somewhat more speculative consideration of the significance of these discourses by asking what might have been at stake when journalists and other writers deployed such differing representations of biological warfare

    Excess of cardiovascular mortality among node-negative breast cancer patients irradiated for inner-quadrant tumors

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    Background: Radiotherapy of the left breast is associated with higher cardiovascular mortality linked to cardiotoxic effect of irradiation. Radiotherapy of inner quadrants can be associated with greater heart irradiation, but no study has evaluated the effect of inner-quadrant irradiation on cardiovascular mortality. Patients and methods: We identified 1245 women, the majority with breast-conserving surgery, irradiated for primary node-negative breast cancer from 1980 to 2004 registered at the Geneva Cancer Registry. We compared breast cancer-specific and cardiovascular mortality between inner-quadrant (n = 393) versus outer-quadrant tumors (n = 852) by multivariate Cox regression analysis. Results: After a mean follow-up of 7.7 years, 28 women died of cardiovascular disease and 91 of breast cancer. Patients with inner-quadrant tumors had a more than doubled risk of cardiovascular mortality compared with patients with outer-quadrant tumors (adjusted hazard ratio 2.5; 95% confidence interval 1.1-5.4). Risk was particularly increased in the period with higher boost irradiation. Patients with left-sided breast cancer had no excess of cardiovascular mortality compared with patients with right-sided tumors. Conclusions: Radiotherapy of inner-quadrant breast cancer is associated with an important increase of cardiovascular mortality, a possible result of higher irradiation of the heart. For patients with inner-quadrant tumors, the heart should be radioprotecte

    Incorporating fine-scale environmental heterogeneity into broad-extent models

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    A key aim of ecology is to understand the drivers of ecological patterns, so that we can accurately predict the effects of global environmental change. However, in many cases, predictors are measured at a finer resolution than the ecological response. We therefore require data aggregation methods that avoid loss of information on fine-grain heterogeneity. We present a data aggregation method that, unlike current approaches, reduces the loss of information on fine-grain spatial structure in environmental heterogeneity for use with coarse-grain ecological datasets. Our method contains three steps: (a) define analysis scales (predictor grain, response grain, scale-of-effect); (b) use a moving window to calculate a measure of variability in environment (predictor grain) at the process-relevant scale (scale-of-effect); and (c) aggregate the moving window calculations to the coarsest resolution (response grain). We show the theoretical basis for our method using simulated landscapes and the practical utility with a case study. Our method is available as the grainchanger r package. The simulations show that information about spatial structure is captured that would have been lost using a direct aggregation approach, and that our method is particularly useful in landscapes with spatial autocorrelation in the environmental predictor variable (e.g. fragmented landscapes) and when the scale-of-effect is small relative to the response grain. We use our data aggregation method to find the appropriate scale-of-effect of land cover diversity on Eurasian jay Garrulus glandarius abundance in the UK. We then model the interactive effect of land cover heterogeneity and temperature on G. glandarius abundance. Our method enables us quantify this interaction despite the different scales at which these factors influence G. glandarius abundance. Our data aggregation method allows us to integrate variables that act at varying scales into one model with limited loss of information, which has wide applicability for spatial analyses beyond the specific ecological context considered here. Key ecological applications include being able to estimate the interactive effect of drivers that vary at different scales (such as climate and land cover), and to systematically examine the scale dependence of the effects of environmental heterogeneity in combination with the effects of climate change on biodiversity
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