Which patellofemoral joint imaging features are associated with patellofemoral pain? Systematic review and meta-analysis

Objectives: To review the association between patellofemoral joint (PFJ) imaging features and patellofemoral pain (PFP). Design: A systematic review of the literature from AMED, CiNAHL, Cochrane Central Register of Controlled Trials (CENTRAL), MEDLINE, PEDro, EMBASE and SPORTDiscus was undertaken from their inception to September 2014. Studies were eligible if they used magnetic resonance imaging (MRI), computed tomography (CT), ultrasound (US) or x-ray (XR) to compare PFJ features between a PFP group and an asymptomatic control group in people < 45 years of age. A pooled meta-analysis was conducted and data was interpreted using a best evidence synthesis. Results: Forty studies (all moderate to high quality) describing 1,043 people with PFP and 839 controls were included. Two features were deemed to have a large standardised mean difference (SMD) based on meta-analysis: an increased MRI bisect offset at 0° knee flexion under load (0.99; 95% CI: 0.49, 1.49) and an increased CT congruence angle at 15° knee flexion, both under load (1.40 95% CI: 0.04, 2.76) and without load (1.24; 95% CI: 0.37,2.12). A medium SMD was identified for MRI patella tilt and patellofemoral contact area. Limited evidence was found to support the association of other imaging features with PFP. A sensitivity analysis showed an increase in the SMD for patella bisect offset at 0° knee flexion (1.91; 95% CI: 1.31,2.52) and patella tilt at 0° knee flexion (0.99; 95% CI: 0.47,1.52) under full weight bearing. Conclusion: Certain PFJ imaging features were associated with PFP. Future interventional strategies may be targeted at these features

Do structural changes (eg, collagen/matrix) explain the response to therapeutic exercises in tendinopathy: A systematic review

Background: Previous reviews have highlighted the benefit of loaded therapeutic exercise in the treatment of tendinopathy. Changes in observable structural outcomes have been suggested as a possible explanation for this response to therapeutic exercise. However, the mechanism for the efficacy of therapeutic exercise remains unclear. Objective: To systematically review the relationship between the observable structural change and clinical outcomes following therapeutic exercise. Data sources: An electronic search of AMED, CiNAHL, Cochrane Central Register of Controlled Trials (CENTRAL), MEDLINE, PEDro and SPORTDiscus was undertaken from their inception to June 2012. Study eligibility criteria: Any study design that incorporated observable structural outcomes and clinical outcomes when assessing the effect of therapeutic exercise on participants with tendinopathy. Study appraisal and synthesis methods: Included studies were appraised for risk of bias using the tool developed by the Cochrane Back Review Group. Due to heterogeneity of studies, a qualitative synthesis was undertaken. Results: Twenty articles describing 625 patients were included. Overall, there is a strong evidence to refute any observable structural change as an explanation for the response to therapeutic exercise when treated by eccentric exercise training. Moderate evidence does exist to support the response of heavy-slow resistance training (HSR). Conclusions and implications of key findings: The available literature does not support observable structural change as an explanation for the response of therapeutic exercise except for some support from HSR. Future research should focus on indentifying other explanations including neural, biochemical and myogenic changes. Registration: Number Registered with PROSPERO, registration number CRD42011001638. Copyright Article author (or their employer) 2012

An updated tribal classification of Lamiaceae based on plastome phylogenomics

Background: A robust molecular phylogeny is fundamental for developing a stable classification and providing a solid framework to understand patterns of diversification, historical biogeography, and character evolution. As the sixth largest angiosperm family, Lamiaceae, or the mint family, consitutes a major source of aromatic oil, wood, ornamentals, and culinary and medicinal herbs, making it an exceptionally important group ecologically, ethnobotanically, and floristically. The lack of a reliable phylogenetic framework for this family has thus far hindered broad-scale biogeographic studies and our comprehension of diversification. Although significant progress has been made towards clarifying Lamiaceae relationships during the past three decades, the resolution of a phylogenetic backbone at the tribal level has remained one of the greatest challenges due to limited availability of genetic data. Results: We performed phylogenetic analyses of Lamiaceae to infer relationships at the tribal level using 79 protein-coding plastid genes from 175 accessions representing 170 taxa, 79 genera, and all 12 subfamilies. Both maximum likelihood and Bayesian analyses yielded a more robust phylogenetic hypothesis relative to previous studies and supported the monophyly of all 12 subfamilies, and a classification for 22 tribes, three of which are newly recognized in this study. As a consequence, we propose an updated phylogenetically informed tribal classification for Lamiaceae that is supplemented with a detailed summary of taxonomic history, generic and species diversity, morphology, synapomorphies, and distribution for each subfamily and tribe. Conclusions: Increased taxon sampling conjoined with phylogenetic analyses based on plastome sequences has provided robust support at both deep and shallow nodes and offers new insights into the phylogenetic relationships among tribes and subfamilies of Lamiaceae. This robust phylogenetic backbone of Lamiaceae will serve as a framework for future studies on mint classification, biogeography, character evolution, and diversification. Graphical abstract: [Figure not available: see fulltext.]. © 2021, The Author(s).Ten Thousand Talent Plans for Young Top-notch Talents of Yunnan Province: YNWR-QNBJ-2018-279National Science Foundation, NSF: TUBITAK-BIDEB 2219, DEB-1655611RG19-172019FI009This study was in part supported by Yunnan Fundamental Research Projects (Grant No. 2019FI009) and “Ten Thousand Talents Program of Yunnan” (Grant No. YNWR-QNBJ-2018-279) awarded to CLX, the CAS “Light of West China” program to CLX and YPC, the Australian Biological Resources Study National Taxonomy Research Grant Program (Grant No. RG19-17) awarded to TCW, CLX, and BL, NSF DEB-1655611 awarded to BTD, and the Postdoctoral Research Program (TUBITAK-BIDEB 2219) awarded to FC

White dwarfs in Galactic plane

Item does not contain fulltextHere, we use the primary detections of the VPHAS+ data release 2 (DR2) (Drew et al., 2014, Cat. II/341), accessible through the ESO Science Archive. It delivers PSF magnitudes, expressed in the Vega system, for 24 per cent of the survey area. We acquired optical spectroscopy for 17 white dwarf candidates on 2014 April 28-30 with the visual and near-UV FOcal Reducer and low dispersion Spectrograph (FORS2), mounted on the Very Large Telescope (VLT) UT1 (Antu)

UVEX sources spectroscopic follow-up

Item does not contain fulltextWe present the results of the first spectroscopic follow-up of 132 optically blue ultraviolet (UV)-excess sources selected from the UV-Excess Survey of the Northern Galactic Plane (UVEX). The UV-excess spectra are classified into different populations and grids of model spectra are fitted to determine spectral types, temperatures, surface gravities and reddening. From this initial spectroscopic follow-up 95 per cent of the UV-excess candidates turn out to be genuine UV-excess sources such as white dwarfs, white dwarf binaries, subdwarf types O and B, emission-line stars and quasi stellar objects. The remaining sources are classified as slightly reddened main-sequence stars with spectral types later than A0V. The fraction of DA white dwarfs is 47 per cent with reddening smaller than E(B-V)≤0.7mag. Relations between the different populations and their UVEX photometry, Galactic latitude and reddening are shown. A larger fraction of UVEX white dwarfs is found at magnitudes fainter than g>17 and Galactic latitude smaller than |b|<4 compared to main-sequence stars, blue horizontal branch stars and subdwarfsnul

UVEX sources spectroscopic follow-up

We present the results of the first spectroscopic follow-up of 132 optically blue ultraviolet (UV)-excess sources selected from the UV-Excess Survey of the Northern Galactic Plane (UVEX). The UV-excess spectra are classified into different populations and grids of model spectra are fitted to determine spectral types, temperatures, surface gravities and reddening. From this initial spectroscopic follow-up 95 per cent of the UV-excess candidates turn out to be genuine UV-excess sources such as white dwarfs, white dwarf binaries, subdwarf types O and B, emission-line stars and quasi stellar objects. The remaining sources are classified as slightly reddened main-sequence stars with spectral types later than A0V. The fraction of DA white dwarfs is 47 per cent with reddening smaller than E(B-V)≤0.7mag. Relations between the different populations and their UVEX photometry, Galactic latitude and reddening are shown. A larger fraction of UVEX white dwarfs is found at magnitudes fainter than g>17 and Galactic latitude smaller than |b|<4 compared to main-sequence stars, blue horizontal branch stars and subdwarf

A planetary nebula around Nova V458 Vulpeculae undergoing flash ionization

Original article can be found at: http://www.iop.org/EJ/journal/apjl Copyright American Astronomical Society [Full text of this article is not available in the UHRA]Peer reviewe

INITIAL DATA RELEASE OF THEKEPLER-INT SURVEY

This paper describes the first data release of the Kepler-INT Survey (KIS), that covers a 116 deg2 region of the Cygnus and Lyra constellations. The Kepler field is the target of the most intensive search for transiting planets to date. Despite the fact that the Kepler mission provides superior time series photometry, with an enormous impact on all areas of stellar variability, its field lacks optical photometry complete to the confusion limit of the Kepler instrument necessary for selecting various classes of targets. For this reason, we follow the observing strategy and data reduction method used in the IPHAS and UVEX galactic plane surveys in order to produce a deep optical survey of the Kepler field. This initial release concerns data taken between May and August 2011, using the Isaac Newton Telescope on the island of La Palma. Four broadband filters were used, U, g, r, i, as well as one narrowband one, Halpha, reaching down to a 10-sigma limit of around 20th mag in the Vega system. Observations covering around 50 deg2, thus about half of the field, passed our quality control thresholds and constitute this first data release. We derive a global photometric calibration by placing the KIS magnitudes as close as possible to the Kepler Input Catalog (KIC) photometry. The initial data release catalogue containing around 6 million sources from all the good photometric fields is available for download from the KIS webpage, as well as via MAST.Comment: 10 pages, 7 figures - Accepted for publication in the Astronomical Journa