Apropa't a la ciencia

Presentamos una propuesta didáctica que permite contextualizar la ciencia en la sociedad: el taller ¿Cómo será la ciencia del futuro? realizado durante la exposición “Apropa’t a la ciència”, realizada en el Palau Robert de Barcelona entre abril y junio del 2007. El taller promueve la creatividad y la reflexión sobre la actividad científica, así como el debate sobre la relación entre la ciencia y la sociedad, mediante la discusión de noticias que sean portada de periódico en el año 2060, creadas por grupos de estudiantes después de su visita a la exposición. Analizamos la percepción social de ciencia, la inclusión de aspectos sociales y los temas les resultan más atractivos a partir de sus producciones e ideas previas. Simultáneamente nos interesa indagar la existencia o no de diferencias atribuibles al género en las visiones del alumnado

Hydrodynamic Characterization of the Polyodon spathula

Among the various functions of the paddlefish rostrum, it is also believed to serve as a stabilizer to counteract the downward force that would otherwise occur during the process of filter feeding. From its unique shape, it is hypothesized that the paddlefish rostrum serves to generate a substantial amount of lift that naturally occurs as the rostrum is elevated at the same time the fish opens its mouth. The present, numerical study is an attempt to quantify the amount of lift (and drag) that is generated by the rostrum of a juvenile paddlefish. Additionally, this data is compared with other hydrofoils. The results suggest that the paddlefish rostrum does indeed produce substantial lift at certain angles of attack. In fact, the results indicate that the amount of lift is comparable to that produced by a symmetric foil (NACA 0012)

Hierarchical Spatial Organization of Geographical Networks

In this work we propose the use of a hirarchical extension of the polygonality index as a means to characterize and model geographical networks: each node is associated with the spatial position of the nodes, while the edges of the network are defined by progressive connectivity adjacencies. Through the analysis of such networks, while relating its topological and geometrical properties, it is possible to obtain important indications about the development dynamics of the networks under analysis. The potential of the methodology is illustrated with respect to synthetic geographical networks.Comment: 3 page, 3 figures. A wokring manuscript: suggestions welcome

The Enactment of Professional Learning Policies: Performativity and Multiple Ontologies

While teacher learning has become a locus of school reform across many international settings, there is relatively little examination of the idiosyncratic ways in which policy discourses on teacher learning are enacted in schools. In this paper, we aim to investigate how these policy discourses are translated and configured into practices and thus, enacted into concrete realities. Using the conceptual notion of multiple ontologies proposed by Mol (1999; 2004), we argue that teacher learning is actualized in a multiplicity of socio-material entanglements, not as a single reality, but as a multiplicity of realities that coexist, simultaneously, in the mesh of assemblages that we call “school”. In this study, we describe and trace how particular socio-material configurations of teacher learning produce concrete realities of practice that mobilize and generate specific networked effects. We conclude that the postulation of multiple ontologies of teacher learning prompts a shift in how policy makers could conceive of and develop strategies aimed at transforming teaching practices

Transversalitat i coeducació a l'àrea de Física i Química en l'ESO : la classificació dels elements químics

Amb esta comunicació es posa de manifest que a l’any 2009 encara cal eixir al pas de les visions deformades de la ciència que ofereixen gran part dels materials curriculars. Planteja una proposta didàctica per a - contribuir a llevar les visions deformades que, de la ciència té el nostre alumnat: descontextualitzada, individualista i elitista, empiro-inductivista i ateòrica, rígida, algorítmica i infalible, aproblemàtica i ahistòrica, exclusivament analítica, visió acumulativa i de creixement lineal (GIL PÉREZ, Daniel; et al 2001). - tenir una imatge menys distorsionada de la realitat relacionant la ciència amb la societat, la tecnologia i el medi ambient des de la perspectiva de gènere. - donar una imatge més ajustada de la ciència que la que presenten la majoria de llibres de text

Comparative analysis of the biosimilar and innovative G-CSF modulated pathways on umbilical cord blood–derived mononuclear cells

Biosimilars of granulocyte colony-stimulating factor (G-CSF) have been routinely introduced into clinical practice. However, not functional genomics characterization has been performed yet in comparison with the innovator G-CSF. This study aimed to evaluate the transcriptomic changes in an in vitro model of umbilical cord blood cells (UBC) exposed to G-CSF for the identification of their modulated pathways. Umbilical cord blood cells–derived mononuclear cells (MNCs) were treated with biosimilar and innovator G-CSF for further gene expression profiling analysis using a microarray-based platform. Comparative analysis of biosimilar and innovator G-CSF gene expression signatures allowed us to identify the most commonly modulated pathways by both drugs. In brief, we observed predominantly upmodulation of transcripts related to PI3K-Akt, NF-kappaB, and tumor necrosis factor (TNF) signaling pathways as well as transcripts related to negative regulation of apoptotic process among others. In addition, hematopoietic colony-forming cell assays corroborate the G-CSF phenotypic effects over UBC-derived MNCs. In conclusion, our study suggests that G-CSF impacts UBC-derived cells through the modulation of several signaling pathways associated with cell survival, migration, and proliferation. The concordance observed between biosimilar and innovator G-CSF emphasizes their similarity in regards to their specificity and biological responses.Fil: Ávila Portillo, Luz Mabel. Universidad Nacional de Colombia; Colombia. Stem Medicina Regenerativa/CryoHoldco; Colombia. Hospital Militar Central. Unidad de Investigación; ColombiaFil: Aristizabal, F.. Universidad Nacional de Colombia; ColombiaFil: Perdomo, S.. Universidad El Bosque. Facultad de Odontología; ColombiaFil: Riveros, A.. Stem Medicina Regenerativa/CryoHoldco; ColombiaFil: Ospino, B.. Stem Medicina Regenerativa/CryoHoldco; ColombiaFil: Avila, J. P.. Stem Medicina Regenerativa/CryoHoldco; ColombiaFil: Butti, M.. Universidad Nacional de La Plata. Facultad de Ciencias Médicas. Centro de Investigaciones Inmunológicas Básicas y Aplicadas; Argentina. Provincia de Buenos Aires. Gobernación. Comisión de Investigaciones Científicas; ArgentinaFil: Abba, Martín Carlos. Universidad Nacional de La Plata. Facultad de Ciencias Médicas. Centro de Investigaciones Inmunológicas Básicas y Aplicadas; Argentina. Provincia de Buenos Aires. Gobernación. Comisión de Investigaciones Científicas; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata; Argentin

Transversalitat i coeducació a l'àrea de Física i Química en l'ESO : la classificació dels elements químics

Amb esta comunicació es posa de manifest que a l'any 2009 encara cal eixir al pas de les visions deformades de la ciència que ofereixen gran part dels materials curriculars. Planteja una proposta didàctica per a - contribuir a llevar les visions deformades que, de la ciència té el nostre alumnat: descontextualitzada, individualista i elitista, empiro-inductivista i ateòrica, rígida, algorítmica i infalible, aproblemàtica i ahistòrica, exclusivament analítica, visió acumulativa i de creixement lineal (GIL PÉREZ, Daniel; et al 2001). - tenir una imatge menys distorsionada de la realitat relacionant la ciència amb la societat, la tecnologia i el medi ambient des de la perspectiva de gènere. - donar una imatge més ajustada de la ciència que la que presenten la majoria de llibres de text

Identifying factors associated with sedentary time after stroke. Secondary analysis of pooled data from nine primary studies.

<p><b>Background</b>: High levels of sedentary time increases the risk of cardiovascular disease, including recurrent stroke.</p> <p><b>Objective</b>: This study aimed to identify factors associated with high sedentary time in community-dwelling people with stroke.</p> <p><b>Methods</b>: For this data pooling study, authors of published and ongoing trials that collected sedentary time data, using the activPAL monitor, in community-dwelling people with stroke were invited to contribute their raw data. The data was reprocessed, algorithms were created to identify sleep-wake time and determine the percentage of waking hours spent sedentary. We explored demographic and stroke-related factors associated with total sedentary time and time in uninterrupted sedentary bouts using unique, both univariable and multivariable, regression analyses.</p> <p><b>Results</b>: The 274 included participants were from Australia, Canada, and the United Kingdom, and spent, on average, 69% (SD 12.4) of their waking hours sedentary. Of the demographic and stroke-related factors, slower walking speeds were significantly and independently associated with a higher percentage of waking hours spent sedentary (p = 0.001) and uninterrupted sedentary bouts of <i>>30</i> and <i>>60 min</i> (p = 0.001 and p = 0.004, respectively). Regression models explained 11–19% of the variance in total sedentary time and time in prolonged sedentary bouts.</p> <p><b>Conclusion</b>: We found that variability in sedentary time of people with stroke was largely unaccounted for by demographic and stroke-related variables. Behavioral and environmental factors are likely to play an important role in sedentary behavior after stroke. Further work is required to develop and test effective interventions to address sedentary behavior after stroke.</p

Resistencia de Phytophthora Infestans (Montagne) de Bary a Metalaxil, en Cultivo de Papas en el Norte de Chile

The objective of this study was to determine the sensitivity to metalaxyl of two populations of Phytophthora infestans (Montagne) de Bary, affecting potato (Solanum tuberosum L.) crops in the IV and V Regions of Chile. A total of 254 isolates were studied in vitro and in vivo which were initially classified as sensitive or resistant according to their growth on Rye B media amended with 10 mg L-1 metalaxyl. CE 50 (effective concentration) values were estimated for each isolate from a regression curve of relative colony growth expressed in Probit unit versus six metalaxyl concentrations (0, 150, 250, 350, 450 and 550 mg L-1). The results of both years showed that all P. infestans isolates collected were resistant to metalaxyl. The CE 50 values for the isolates collected during 1999 in the IV Region ranged between 243 and 687 mg L-1 of metalaxyl, 9.6% of the isolates showed CE 50 values under 300 mg L-1. The CE 50 values for the isolates collected in the V Region showed values between 233 to 633 mg L-1 of metalaxyl, and 10.1% of the isolates showed CE 50 values lower than 300 mg L-1 of metalaxyl. All the isolates collected during 2000 were resistant to metalaxyl in both regions, 89.6 and 78.1% of the isolates collected in the IV and V region showed CE 50 values higher than 350 mg L-1 of metalaxyl respectively. The result of the metalaxyl sensitivity bioassay performed in a representative number of isolates showed similar results to the in vitro assay. This is the first report of resistance to metalaxyl in Chile.Con el objeto de determinar la sensibilidad a metalaxil de dos poblaciones de Phytophthora infestans (Montagne) de Bary, en cultivos de papa (Solanum tuberosum L.) en diferentes localidades de la IV y V Regi\uf3n de Chile, se estudiaron mediante ensayos in vitro e in vivo 254 aislamientos, los cuales inicialmente fueron calificado como sensibles o resistentes de acuerdo a su crecimiento sobre agar centeno B y 10 mg L-1 de metalaxil. Su concentraci\uf3n efectiva media (CE 50), fue estimada mediante un modelo de regresi\uf3n lineal entre el logaritmo de seis concentraciones de metalaxil (0, 150, 250, 350, 450 y 550 mg L-1) y porcentaje de inhibici\uf3n transformado a unidades Probit. Los resultados de ambas temporadas demostraron que la totalidad de los aislamientos de P. infestans fueron resistentes a metalaxil. Aislamientos colectados en la IV Regi\uf3n durante 1999 presentaron variaciones de CE 50 entre 243 y 687 mg L-1 de metalaxil, 9,6% de ellos prresent\uf3 CE 50 inferior a 300 mg L-1 de metalaxil. Aislamientos colectados en la V Regi\uf3n variaron su CE 50 entre 233 y 633 mg L-1 de metalaxil y solamente 10,1% de ellos present\uf3 CE 50 inferior a 300 mg L-1 de metalaxil. La totalidad de los aislamientos colectados en la temporada 2000 fueron resistentes al fungicida, 89,6 y 78,1% de los colectados en la IV y V Regi\uf3n respectivamente, presentaron CE 50 superiores a 350 mg L-1 de metalaxil. Los resultados del bioensayo fueron consistentes con el trabajo in vitro

ARTICULAR PAIN IS CORRELATED WITH ULTRASOUND POWER DOPPLER FINDINGS?

Universidade Federal de São Paulo, Div Rheumatol, São Paulo, BrazilUniversidade Federal de São Paulo, Div Radiol, São Paulo, BrazilUniv Politecn Marche, Div Rheumatol, Jesi, ItalyUniversidade Federal de São Paulo, Div Rheumatol, São Paulo, BrazilUniversidade Federal de São Paulo, Div Radiol, São Paulo, BrazilWeb of Scienc