60 research outputs found

    Neki podaci o sojeničkim naseljima u Bihaćkom polju

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    Neki podaci o sojeničkim naseljima u Bihaćkom polju

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    Krčana - naselje mlađeg željeznog doba u selu Trnovi u sjeverozapadnoj Bosni

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    Novootkriveni lokalitet Krčana dao je pretežno keramički materijal, najvećim dijelom nastao na autohtoni način, ali se pojavljuju i fragmenti karakteristične latenske keramike izrađeni na lončarskom kolu. Na osnovu geografskog položaja i komparacije s materijalom nađenim na lokalitetima u današnjoj Hrvatskoj (Kirin-grad, Turska kosa i dr.) naselje je pripisano Kolapijanima posljednjih stoljeća prije Krista; naznačene su one karakteristike kulture ovoga plemena za koje je istraživanje Krčane pružilo dovoljno elemenata

    The quantified self: what counts in the neoliberal workplace

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    Implementation of quantified self technologies in workplaces relies on the ontological premise of Cartesian dualism with mind dominant over body. Contributing to debates in new materialism, we demonstrate that workers are now being asked to measure our own productivity and health and wellbeing in art-houses and warehouses alike in both the global north and south. Workers experience intensified precarity, austerity, intense competition for jobs, and anxieties about the replacement of labour-power with robots and other machines as well as, ourselves replaceable, other humans. Workers have internalized the imperative to perform, a subjectification process as we become observing, entrepreneurial subjects and observed, objectified labouring bodies. Thinking through the implications of the use of wearable technologies in workplaces, this article shows that these technologies introduce a heightened Taylorist influence on precarious working bodies within neoliberal workplaces

    Strike, occupy, transform! Students, subjectivity and struggle

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    This article uses student activism to explore the way in which activists are challenging the student as consumer model through a series of experiments that blend pedagogy and protest. Specifically, I suggest that Higher Education is increasingly becoming an arena of the postpolitical, and I argue that one of the ways this student-consumer subjectivity is being (re)produced is through a series of ‘depoliticisation machines’ operating within the university. This article goes on to claim that in order to counter this, some of those resisting the neoliberalisation of higher education have been creating political-pedagogical experiments that act as ‘repoliticisation machines’, and that these experiments countered student-consumer subjectification through the creation of new radical forms of subjectivity. This paper provides an example of this activity through the work of a group called the Really Open University and its experiments at blending, protest, pedagogy and propaganda

    ‘The smell of the place’: Managerialist culture in contemporary UK business schools

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    © 2014 Taylor & Francis. By introducing an intentionally provocative critique of managerialist regimes which typify contemporary UK business school culture, we argue that current business school management practices generate a climate of mistrust and alienation amongst academics. Such a climate is not conducive to a reformative agenda that business schools should be pursuing if they are to improve staff morale and the educational environment. Drawing on Ghoshal’s ‘smell of the place’ metaphor to structure this argument, we court deliberate irony and paradox. Rather than draw on heterodox theory to inform our critique we, instead, turn relatively mainstream management and organization theory against itself. Our argument is that even when examined through orthodox lenses, managerialist practices are found wanting and contradict the precepts of much mainstream normative theory

    Incorporating radiomics into clinical trials: expert consensus on considerations for data-driven compared to biologically-driven quantitative biomarkers

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    Existing Quantitative Imaging Biomarkers (QIBs) are associated with known biological tissue characteristics and follow a well-understood path of technical, biological and clinical validation before incorporation into clinical trials. In radiomics, novel data-driven processes extract numerous visually imperceptible statistical features from the imaging data with no a priori assumptions on their correlation with biological processes. The selection of relevant features (radiomic signature) and incorporation into clinical trials therefore requires additional considerations to ensure meaningful imaging endpoints. Also, the number of radiomic features tested means that power calculations would result in sample sizes impossible to achieve within clinical trials. This article examines how the process of standardising and validating data-driven imaging biomarkers differs from those based on biological associations. Radiomic signatures are best developed initially on datasets that represent diversity of acquisition protocols as well as diversity of disease and of normal findings, rather than within clinical trials with standardised and optimised protocols as this would risk the selection of radiomic features being linked to the imaging process rather than the pathology. Normalisation through discretisation and feature harmonisation are essential pre-processing steps. Biological correlation may be performed after the technical and clinical validity of a radiomic signature is established, but is not mandatory. Feature selection may be part of discovery within a radiomics-specific trial or represent exploratory endpoints within an established trial; a previously validated radiomic signature may even be used as a primary/secondary endpoint, particularly if associations are demonstrated with specific biological processes and pathways being targeted within clinical trials

    SPINART study : validation of the extended magnetic resonance imaging scale for evaluation of joint status in adult patients with severe haemophilia A using baseline data

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    Introduction: Most previous joint imaging scales for haemophilia have focused on earlier disease stages observed in younger patients. Aim: We sought to demonstrate that the 45-item extended magnetic resonance imaging (eMRI) scale is a valid instrument for measuring joint status in adults with severe haemophilia A. Methods: Six scale categories (effusion/haemarthrosis, synovial hypertrophy, hemosiderin, erosion, subchondral cysts and cartilage loss) in two domains (soft tissue [range = 0–9] and osteochondral [range = 0–36]) were evaluated for each joint. eMRI scores were derived using baseline data from a randomized, controlled, parallel-group clinical trial (SPINART). Quantitative analysis of linearity included assessments of the relationship between scores derived from the eMRI scale vs. the 17-point International Prophylaxis Study Group (IPSG) MRI scale and Colorado Adult Joint Assessment Scale (CAJAS). Results: Patient eMRI scores correlated with age (r = 0.58), consistent with the expectation of arthropathy progression and more severe joint changes in older patients. eMRI scores demonstrated excellent between-reader agreement for overall patient score (intraclass correlation coefficient [ICC] = 0.88) and outstanding agreement for knee evaluations (ICC = 0.95). There was a strong linear relationship of the eMRI score with the CAJAS (r = 0.7). Adding individual bone evaluations for each joint increased the sensitivity of the instrument to detect change at low scores. There was minimal ceiling effect (5% maximum scores for all evaluated joints) compared with the IPSG MRI scale (20%). Internal reliability was good (overall Cronbach's alpha = 0.75). Conclusions: Overall, the eMRI scale represents a valid and reliable measure of joint status in adolescents and adults with severe haemophilia A
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