Participatory Cultural Heritage Protection

Dünyada olduğu gibi ülkemizde de kurumsal sosyal sorumluluk çalışmaları kapsamında yürütülen, “sponsorluk uygulamaları”, “yap işlet devret”, “restore et işlet devret”, “kar ortaklığı” gibi kamu-yerel-sivil-özel işbirliğini destekleyen faaliyetlerin, kültürel mirasın sürdürülebilir anlayışla (evrensel koruma ilkeleri temelinde) korunmasına yönelik uygulamalarda anahtar görev görebileceği değerlendirilmektedir. Bu uygulamalar sayesinde korunması gerekli kültür varlıkları ve alanlarının, kamu kaynakları dışındaki kaynaklarla da ihya edilmesiyle bu evrensel değerlerin gelecek kuşaklara bırakılması sağlanabilir. Bu bağlamda, sivil mimarlık örnekleri, anıtsal yapılar ve kentsel sit alanlarında gerçekleştirilebilen bu uygulamaların daha sistemli hale getirilmesinin yanı sıra, ülkemizin arkeolojik alanlarında da kullanılabilir bir yöntem olarak geliştirilmesi bu çalışmanın temel hedefi ni oluşturmaktadır. Çalışmada ülkemizdeki mevcut yasal düzenlemeler tartışılırken, uluslararası ölçekte katılımcı süreçler ve kültür varlıklarının fonksiyonel kullanımlarıyla ilgili bazı tespitlere yer verilecek, bir taraftan da korumada katılımcı süreçlerin gerekliliği tartışılacaktır. Ülkemizdeki kültürel mirasın korunmasında bir “kültürel miras politikası” nın varlığının önemi ve gereğinin yanı sıra, nasıl ve hangi kriterleri gözeten bir politika olması gerektiği de ortaya konulacaktı

Comparative study of annealing and gold dopant effect on DC sputtered vanadium oxide films for bolometer applications

Vanadium oxide (VOx) thin film has been widely used for IR detectors and it is one of the promising materials for THz detectors due to its high temperature coefficient of resistance (TCR) values. VOx films with proper TCR values have also high resistance and it restricts bolometer performance especially for uncooled bolometers. To overcome this problem, deposition at elevated temperatures or annealing approach has been accepted and used but gold co-deposition approach has been proposed recently. In this study, vanadium oxide films were fabricated on high resistivity silicon substrates by reactive direct current magnetron sputtering in different O2/Ar atmosphere at room temperature. We investigated influence of oxygen partial pressure during deposition process and fabricated VOx thin films with sufficient TCR values for bolometer applications. In order to decrease resistivity of the deposited films, post annealing and gold doping approaches were performed separately. Effect of both post annealing process and gold doping process on structural and electrical properties of VOx thin films deposited at room temperature were investigated and detailed comparison between these methods were presented. We obtained the best possible approach to obtain optimum conditions for the highly reproducible VOx thin films which have the best resistivity and suitable TCR value for bolometer applications.TUBITAK (Scientific and Technological Research Council of Turkey); 115F54

The Effect of Obturator Nerve Blockade on Oncological Outcomes of Patients with Lateral Wall Localized Non-Muscle Invasive Bladder Cancer

Objective:To investigate the effect of obturator nerve blockade on oncological outcomes of patients with a diagnosis of lateral wall localized non-muscle invasive bladder cancer.Materials and Methods:One hundred six patients diagnosed with lateral wall localized non-invasive bladder cancer were evaluated between January 2015 and March 2020 in this retrospective, cross-sectional observational study. The patients were divided into two groups: patients receiving only spinal anesthesia and those receiving spinal anesthesia combined with ultrasound-guided obturator nerve blockade. Oncological outcomes of the groups were compared statistically.Results:We observed recurrent tumors in 25 patients (45.5%) in Group 1 and 11 patients (21.6%) in Group 2. Additionally, we observed tumor progression in eight patients (14.5%) in Group 1 and two patients (3.9%) in Group 2. We observed statistical significance in differences between groups regarding tumor size, recurrence rate, adequate muscle tissue sampling, ability for complete resection, and persistent obturator reflex. The efficacy rate of obturator blockade was 92.1% in Group 2. One-year recurrence-free survival (RFS) was 98.0% and 5-year RFS was 23.5% for Group 1, while for Group 2, they were 97.4% and 57.2%, respectively.Conclusion:The obturator reflex is a common and challenging reflex that may cause major complications and result in unintended consequences, such as incomplete resection or tumor recurrence with transurethral resection of bladder tumors. In this study, we demonstrated that combining spinal anesthesia with obturator nerve blockade for lateral wall localized non-muscle invasive bladder cancer may prevent tumor recurrence and reduce peroperative complications

Validity and reliability of the assessment tool for Asthma (ATA) questionnaire: the ATA study

OBJECTIVES: A multicenter trial was designed to validate the “Assessment Tools for Asthma (ATA)” questionnaire, a newly developed questionnaire, which evaluates both asthma control and risk factors associated with asthma control with a single instrument. MATERIALS AND METHODS: This cross-sectional study involved 810 cases from 14 clinics in 9 Turkish cities. The ATA questionnaire and Asthma Control Test (ACT) were administered. The Visual Analog Scale (VAS) was used to evaluate the control status of 100 randomized cases. ATA is an eight-item physician-administered questionnaire. It comprises the following two sections-ATA1, assesses symptomatic control criteria, and the remaining section, queries the flre-up of asthma, control of comorbidities, treatment adherence, and inhaler technique. RESULTS: The mean scores for ATA1, ATA total, VAS, and ACT were 24.7±14.8, 53.8±19, 7.1±3, and 18.8±5.5, respectively. According to the ATA questionnaire, among all patients, 34.3% had controlled, 18.8% had partly controlled, and 46.9% had uncontrolled asthma. Furthermore, 16.6% patients had flre-ups between visits, 96.4% patients had uncontrolled comorbidity, 17% patients had irregular asthma treatment, and only 8.4% patients used the incorrect inhaler technique. The ATA questionnaire showed internal consistency (Cronbach’s alpha coeffiient=0.683). ACT, ATA1, and two specialists’ evaluations using VAS correlated strongly with the ATA total scores (Spearman correlation coeffiient (r) values: 0.776, 0.783, and 0.909, respectively; p-values: p<0.001, p<0.001, and p<0.001, respectively). According to Receiver Operating Characteristic analysis, the cut-off value of ATA was 50 (sensitivity=84.4%, specifiity=82.40%). CONCLUSION: The validated ATA questionnaire may be a practical tool for physicians in asthma management

Kuran kursunda patlama

Diyanet İşleri Başkanlığı'nın son 10 yıldaki çalışmalarına ilişkin hazırladığı raporda her yıl ortalama 4.5 milyon dini kitap basıldığı, sayıları 400'e yaklaşan imam hatip liselerinde 280 binden fazla öğrencinin okuduğu belirlendi. Bu sayı, ortaöğrenim öğrencilerinin sekizde biri

Effects of levosimendan administered after reperfusion in experimental intestinal ischemia reperfusion model

Amaç: Barsak arteriyel kan akımının kısmen veya tamamen tıkanması sonrası intestinal iskemi; kan akımının yeniden sağlanması ile reperfüzyon ortaya çıkmaktadır. İntestinal iskemi reperfüzyon (İİR) hasarı çoklu organ yetersizliğine ve ölüme neden olabilir. Bu çalışmanın amacı İİR hasarı üzerine reperfüzyon sonrası uygulanan levosimendanın etkisinin araştırılmasıdır. Gereç ve Yöntem: DEÜTF Hayvan Deneyleri Yerel Etik Kurulu onayı alındıktan sonra ağırlıkları 250-300 g arasında değişen 21 adet erkek Albino Wistar rat her birinde 7'şer denek olacak şekilde 3 gruba ayrılmıştır. Tüm gruplara arter ve ven kateterizasyonundan sonra laparatomi uygulanmış, süperiyor mezenter arter (SMA) diseke edilmiş, Sham grubuna başka bir işlem yapılmamıştır. İntestinal iskemi reperfüzyon grubunda SMA 60 dk klemplenerek iskemi oluşturulmuş ve klemp açılarak 120 dk reperfüzyon için beklenmiştir. İntestinal iskemi reperfüzyon + Levosimendan (İİR+L) grubunda İİR grubundaki işlemler aynen tekrarlanmıştır, reperfüzyon sonunda 10 dk 12 µg.kg-1 yükleme dozunu takiben 50 dk 0,2 µg.kg-1.dk-1 levosimendan infüzyonu uygulanmıştır. Ratların 10 dakika stabilizasyon süresi sonunda, iskeminin 15, 30, 60. dk'sında, reperfüzyonun 15, 30, 60, 120. dk'sında, levosimendan yükleme dozunun sonunda ve infüzyon sonlandığında ölçülen ortalama arteriyel basınçları (OAB) kaydedilmiştir. Deney sonunda alınan ileum örneklerindeki reperfüzyon hasarının derecesi, biyokimyasal olarak doku malonildialdehit (MDA) düzeyi ölçümü ile; histopatolojik olarak Chiu skoru ile değerlendirilmiştir. İstatistiksel değerlendirmede p< 0.05 anlamlı kabul edilmiştir. Bulgular: Reperfüzyon periyodunun 30. dk OAB değerleri, İİR ve İİR+L gruplarında sham grubuna oranla düşük bulunmuştur. İİR ve İİR+L gruplarında bazale göre reperfüzyonun 15, 30 ve 60. dk değerlerinde azalma izlenmiştir. Grupların doku MDA düzeyleri arasında fark saptanmamıştır. Sham grubunun Chiu skorlarının İİR ve İİR+L grubundan düşük, İİR grubunun ise İİR+L grubuna oranla yüksek olduğu saptanmıştır. Sonuç: İntestinal İR sonrası uygulanan levosimendan infüzyonu OAB'de azalmaya neden olmamış, ince barsak hasarını azaltmış ancak lipid peroksidasyonunu etkilediği gösterilememiştir. Klinik olarak yarar sağlayabilecek bu uygulamanın deneysel olarak ayrıntılandırılması kanaatine varılmıştır. Objectıve: By partial or total occlusion of intestinal arterial blood flow intestinal ischemia; with the blood re-flow reperfusion occurs. Intestinal ischemia reperfusion (IIR) injury can cause multiple organ failure and death. The aim of this study is to investigate the effect of levosimendan administered after reperfusion on IIR injury. Material and Method: After the approval of Local Ethics Committee for Animal Researches of Medical School of Dokuz Eylul University, 21 male Albino Wistar rats weighing 250-300 g were divided into 3 groups, each consisting of 7 subjects. Laparatomy was applied to all groups after arterial and venous catheterisation; superior mesenteric artery (SMA) was dissected. Nothing else was applied to sham group. In IIR group SMA was clamped for 60 min. to cause ischemia and declamped for 120 min. to cause reperfusion. In IIR+L group after clamping of SMA for 60 min. and declamping for 120 min., at the end of the reperfusion following intravenous 12 μg.kg-1 of levosimendan loading dose for 10 min., 0,2 μg.kg-1. h-1 infusion was administered for 50 min. The measured values of mean arterial pressures (MAP) were recorded at 10 minutes after stabilisation of rats; 15th, 30th, 60th minutes of ischemia period; 15th, 30th, 60th, 120th minutes of reperfusion; after levosimendan bolus and at the end of the infusion. The grade of reperfusion injury in ileum samples collected after experiment was evaluated biochemically by tissue malondialdehyde (MDA) measurement; histopathologically by Chiu score. p< 0.05 was accepted as statistically significant. Results: MAP values at the 30th min. of reperfusion period were lower in IIR and IIR+L groups than Sham group. In IIR and IIR+L groups the values at 15th, 30th and 60th min. of reperfusion were decreased compared to basal values. Group's tissue MDA levels was not any difference among groups. Chiu scores of Sham group were lower than IIR and IIR+L groups, whereas Chiu scores of IIR group were determined higher than IIR+L group. Conclusion: Levosimendan infusion administered after intestinal IR did not cause decrease on MAP, reduced intestinal injury however, it can not be shown to affect lipid peroxidation. It is concluded that, this treatment which can be clinically beneficial should be elaborated experimentally

Determination of Anthropometric Measurements that may be Associated with Difficult Intubation in Children

Aim: Difficult tracheal intubation is a fundamental cause of perioperative morbidity and mortality. The frequency of difficult intubation is thought to be higher in the pediatric age group due to the different anatomical and physiological structures, and it may not be easy to detect this beforehand. Anthropometric measurements were evaluated before the elective operation and the relationship of some parameters with difficult intubation. Material and Method: This prospective cross-sectional study was conducted on 90 pediatric patients aged 2-14 who underwent elective surgery under general anesthesia. All patients’ age, gender, height, weight, body surface area (BSA), and body mass index (BMI) records were recorded before the operation. Mallampati scoring, head and neck circumference, thyromental distance measurements, and head circumference/neck circumference ratio were performed. Cormack-Lehane (CL) scoring and endotracheal intubation were applied during direct laryngoscopy of the operated patients. Children with easy intubation (CL grade 1 and 2) group 1; children who underwent difficult intubation (CL grade 3 and 4) were defined as group 2. Results: There was no significant relationship between Groups I and II in terms of age, height and weight values. There was no significant relationship between the two groups with BSA and thyromental distance measurements. Mallampati scores were found to be grades 3 and 4 (3.3%) in three of the 90 patients, and CL scores of 3 and 4 (4.4%) in four patients. A significant correlation was found between Mallampati scoring and CL scoring. A statistically significant difference was found between the two groups regarding head/neck ratios and BMI. Conclusion: In our study, head circumference/neck circumference ratio and BMI were found to be helpful while predicting difficult intubation in children with normal physical characteristics, 2-14 years of age, who underwent elective surgery. Our findings can be supported by further studies that will be planned and include more patients

The effect of neutrophil lymphocyte ratio on mortality in patients followed in the intensive care unit with the diagnosis of ischemic stroke from the emergency department

The goal of this study was to determine if the neutrophil-lymphocyte ratio (NLR) predicts mortality in patients hospitalized in the intensive care unit (ICU) with an ischemic stroke. Between January 1 and December 31, 2021, 116 patients admitted to our emergency department with the diagnosis of ischemic stroke and hospitalized in the 3rd level ICU unit were included in the study and divided into two groups: patients who died (Group 1: n=62) and patients who survived (Group 2: n=54). Patients’ age, gender, presence of chronic diseases, Acute Physiology and Chronic Health Evaluation (APACHE) II score, and neutrophil count, lymphocyte count, and NLR were obtained by dividing these two numbers in the first complete blood count taken at the time of admission to the emergency department were collected and analyzed. While 54 (46.5%) patients were discharged from the ICU, 62 (53.4%) patients died. 60 (51.7%) of the patients were female. The average age of patients was 76.85±10.70. APACHE II score was found to be correlated with mortality (AUC 0.70, 95% CI (0.616-0.802) (p=0.01). When the APACHE II cut-off value was more than 13.5, it predicted mortality with 95% sensitivity and 85% specificity. The median NLR ratio of the patients was found to be 5.08 (0.38-35.16) in the survivors and 11.68 (1.38-113.00) in patients that died. NLR was lower in survivors (p=0.002). NLR may be a valuable marker in predicting mortality in stroke patients admitted to the ICU

İznik Nicaea Antik Kentinin Restorasyon Sürecinde Kullanılabilecek Bölgedeki Antik Ocakların Mermerlerinin Türleri, Malzeme Özellikleri ve Antik Kentteki Bazı Doğal Taş Materyallerin Kökenleri Üzerine Bir Ön Çalışma

İznik Nicaea Antik KentininRestorasyon Sürecinde Kullanılabilecek Bölgedeki Antik Ocakların MermerlerininTürleri, Malzeme Özellikleri&nbsp; ve Antik Kentteki Bazı Doğal Taş MateryallerinKökenleri Üzerine Bir Ön ÇalışmaTypes and Material Characteristics of Marblesof Regional Ancient Quarries used in the Restoration Process in İznik Nicaea and APreliminary Study on the Provenanceof Some Natural Stone Materials in the Ancient CityRamazan HACIMUSTAFAOĞLU, Aygün Ekin MERİÇ, Fatih Hakan KAYA, Hakan ELÇİ &nbsp;&nbsp;(1-4)Dokuz Eylül Üniversitesi Torbalı Meslek Yüksek Okulu Torbalı İzmir Türkiye (2-3) Dokuz Eylül Üniversitesi Edebiyat Fakültesi Arkeoloji Bölümü Tinaztepe Yerleşkesi İzmir Türkiye … ([email protected])</p

Innovation in measuring obese patients’ blood pressure: measurement with conical wrapping technique

TARAMAWOSWOS:000739843400011TARAMAPUBMEDTARAMASCOPUSIntroduction Accurate measurement of blood pressure (BP) is difficult in obese patients due to their upper arm shape and width. Errors made during BP measurement cause misdiagnosis or lead to wrong treatment. Method The data of this methodological study were collected from 40 patients who were 18 years old or above, with a BMI above 25 kg/m2, and who were followed up with radial catheter arterial pressure in adult intensive care and postoperative care units between March and December 2020. Results In total 55% of the participants were male with a mean age of 63.9 years, mean height of 165.7 cm, mean weight of 85.2 kg and mean BMI of 31.0 ± 2.1 kg/m2. Intra-arterial BP (IABP) measurement values were found to be correlated with conical wrapping technique and cylindrical wrapping technique (P < 0.001). As a result, a statistically significance was found between conical SBP and intra-arterial SBP (r = 0.921; P < 0.05) and conical DBP and intra-arterial DBP (r = 0.902; P < 0.05) Conclusion It was determined that the SBP and DBP results of the conical wrapping technique were closer to the results obtained by IABP measurements. For this reason, it is more appropriate to measure BP with conical wrapping technique in clinically obese patients