18 research outputs found

    Antibrowning and antimicrobial effects of onion essential oil to preserve the quality of cut potatoes

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    This study evaluated the effect of onion essential oil (OEO) (0, 0.5, 2.5, and 5 mg ml−1) on microbial growth, browning decay, and sensorial appealing of cut potatoes stored for 15 days at 4 °C. Dipropyl disulphide and dipropyl trisulphide were the main constituents identified in OEO, and its application at a dose of 0.5 mg mlt-1 was the most effective to prevent browning (38.5% inhibition respect to control) during storage, inhibiting PPO activity (39% respect to control) after the treatment. The higher the added OEO concentration the lower microbial growth of the treated product was, achieving a reduction of 1.27 log CFU g−1 for the 5 mg ml−1 treatment. The odour and flavour appealing of cut potatoes were well received by the panelists after 10 days of storage. Therefore, the use of OEO in cut potatoes has a potential as antimicrobial and antibrowning agent

    Evolution of Phenolic Content, Antioxidant Capacity and Phenolic Profile during Cold Pre-fermentative Maceration and Subsequent Fermentation of Cabernet Sauvignon Red Wine

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    The phenolic compound profile and content of red wines are modified during the maceration-fermentation process by several factors that alter the extractability of the compounds and by reactions that phenolic compounds undergo, and can be directly related to the quality of the final wine and its beneficial effects on the consumer. The aim of this study was to determine the change in phenolic content and profile during cold pre-fermentative maceration and fermentation without the removal of grape pomace. Total phenolics,flavonoids, anthocyanins, tannins and antioxidant capacity were determined by spectrophotometric methods, and the phenolic profile was determined by HPLC-MS on each day of the maceration-fermentation process. The results showed a variation in the content of phenolic compounds and antioxidant activity over time, but the final phenolic content showed no significative difference compared with the initial content (1 268 mg GAE/L and 1 115 mg GAE/L respectively). The phenolic profile showed that flavonoids were theprincipal compounds in wine and that they increased at the end of the winemaking. Condensed tannins also increased during fermentation, while anthocyanins and some phenolic acids decreased at the end of the process. The final content of phenolic compounds was similar to the initial one, but there was a change in the different fractions of phenolic compounds at the end of fermentation

    Risk profiles and one-year outcomes of patients with newly diagnosed atrial fibrillation in India: Insights from the GARFIELD-AF Registry.

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    BACKGROUND: The Global Anticoagulant Registry in the FIELD-Atrial Fibrillation (GARFIELD-AF) is an ongoing prospective noninterventional registry, which is providing important information on the baseline characteristics, treatment patterns, and 1-year outcomes in patients with newly diagnosed non-valvular atrial fibrillation (NVAF). This report describes data from Indian patients recruited in this registry. METHODS AND RESULTS: A total of 52,014 patients with newly diagnosed AF were enrolled globally; of these, 1388 patients were recruited from 26 sites within India (2012-2016). In India, the mean age was 65.8 years at diagnosis of NVAF. Hypertension was the most prevalent risk factor for AF, present in 68.5% of patients from India and in 76.3% of patients globally (P < 0.001). Diabetes and coronary artery disease (CAD) were prevalent in 36.2% and 28.1% of patients as compared with global prevalence of 22.2% and 21.6%, respectively (P < 0.001 for both). Antiplatelet therapy was the most common antithrombotic treatment in India. With increasing stroke risk, however, patients were more likely to receive oral anticoagulant therapy [mainly vitamin K antagonist (VKA)], but average international normalized ratio (INR) was lower among Indian patients [median INR value 1.6 (interquartile range {IQR}: 1.3-2.3) versus 2.3 (IQR 1.8-2.8) (P < 0.001)]. Compared with other countries, patients from India had markedly higher rates of all-cause mortality [7.68 per 100 person-years (95% confidence interval 6.32-9.35) vs 4.34 (4.16-4.53), P < 0.0001], while rates of stroke/systemic embolism and major bleeding were lower after 1 year of follow-up. CONCLUSION: Compared to previously published registries from India, the GARFIELD-AF registry describes clinical profiles and outcomes in Indian patients with AF of a different etiology. The registry data show that compared to the rest of the world, Indian AF patients are younger in age and have more diabetes and CAD. Patients with a higher stroke risk are more likely to receive anticoagulation therapy with VKA but are underdosed compared with the global average in the GARFIELD-AF. CLINICAL TRIAL REGISTRATION-URL: http://www.clinicaltrials.gov. Unique identifier: NCT01090362

    Effect of phenolic compounds on the growth of selected probiotic and pathogenic bacteria

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    Fruit extracts from different tissues (pulp, seed and peel) have shown antimicrobial and prebiotic activities related to their phenolic profile, although structure-specific evaluations have not been reported yet. The effect of five phenolic compounds (catechin and gallic, vanillic, ferulic and protocatechuic acids) identified in different fruits, particularly in mango, was evaluated on the growth of two probiotic (Lactobacillus rhamnosusGG ATCC 53103 and Lactobacillus acidophilusNRRLB 4495) and two pathogenic (Escherichia coli 0157:H7 ATCC 43890 and Salmonella enterica serovar Typhimurium ATCC 14028) bacteria. The minimal inhibitory concentration (MIC) and minimal bactericidal concentration (MBC) of phenolic acids ranged from 15–20 mmol l−1 and 20–30 mmol l−1 against E. coli and S. Typhimurium, respectively. For catechin, the MIC and MBC were 35 mmol l−1 and >35 mmol l−1 against E. coli and S. Typhimurium, respectively. The presence of catechin and gallic, protocatechuic and vanillic acids in MRS broth without dextrose allowed the growth of lactobacilli. Catechin combined with protocatechuic or vanillic acid mildly allowed the growth of both probiotics. In conclusion, phenolic compounds can selectively inhibit the growth of pathogenic bacteria without affecting the viability of probiotics. Significance and Impact of the Study: This study provides relevant information about the effects of phenolic compounds commonly present in fruit and vegetables on the growth of probiotic and pathogenic bacteria. The compounds selectively allowed the growth of probiotic lactobacilli (Lactobacillus rhamnosus GG and Lactobacillus acidophilus) and inhibited pathogenic bacteria (Escherichia coli and Salmonella Typhimurium) at the same concentration (20 mmol l−1). These findings can contribute to the formulation of nutraceutical products, such as synbiotics, that can restore or maintain an optimal composition of human microbiota, potentially improving the overall health of the consumer.Fil: Pacheco Ordaz, R.. Centro de Investigacion En Alimentacion y Desarrollo; MéxicoFil: Wall Medrano, A.. Centro de Investigacion En Alimentacion y Desarrollo; México. Universidad Autonoma de Ciudad Juarez; MéxicoFil: Goñi, María Gabriela. Centro de Investigacion En Alimentacion y Desarrollo; México. Universidad Nacional de Mar del Plata. Facultad de Ingeniería; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Mar del Plata; ArgentinaFil: Ramos Clamont Montfort, G.. Centro de Investigacion En Alimentacion y Desarrollo; MéxicoFil: Ayala Zavala, J.F.. Centro de Investigacion En Alimentacion y Desarrollo; MéxicoFil: González Aguilar, G.A.. Centro de Investigacion En Alimentacion y Desarrollo; Méxic

    Controlled release of antifungal volatiles of thyme essential oil from ?-cyclodextrin capsules

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    Thyme essential oil (TO) is a good antimicrobial agent, however, its high volatility and reactivity limits its application as food preservative. ?-cyclodextrin (?-CD) is able to encapsulate organic molecules, forming host-guest complexes with hydrophobic and volatile molecules such as TO constituents, controlling volatility and reactivity. In addition, controlled released of the ?-CD trapped compounds could be possible by exposing the capsules to high relative humidity (RH). With this in mind, the controlled release of antifungal volatiles throughout exposure of TO:?-CD capsules to high relative humidity was studied. Thymol (TOL) was the major constituent of TO, detected by gas chromatography before and after encapsulation. Capsules of the 8:92 ratio (TO:?-CD) showed the highest TOL content. Hydrogen bonds and hydrophobic interactions were detected between the oil constituent and ?-CD by IR and 1H NMR spectroscopy. During moisture sorption, the TO capsules showed a lower water uptake compared with free ?-CD. Similar behavior was observed during water desorption. In all cases, a hysteresis process was observed when comparing sorption and desorption isotherms. At high RH, TOL is displaced and almost 76% is released to the headspace. The growth of Alternaria alternata was inhibited significantly by the addition and exposure to TO:?-CD as measured by both the agar dilution and the headspace method, respectively. Therefore, the encapsulation of antifungal volatile compounds as TO in ?-CD, could be an alternative to control the release of natural antimicrobials that can be of interest to the agricultural area. � Springer Science+Business Media B.V. 2010

    Effect of ripening on physico-chemical properties and bioactive compounds in papaya pulp, skin and seeds

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    47-59Byproducts generated by the food industry represent an alternative to obtain functional ingredients. Byproducts of tropical fruits, such as papaya skin and seeds, represent a source of bioactive compounds (BC), which could change during fruit ripening. Effect of ripening stage (RS) on BC content and antioxidant properties of edible pulp, skin and seeds of papaya cv. Maradol was determined. Papaya skin showed significantly higher ascorbic acid (~250 mg AAE/100 g) content than seeds (~20 mg/100 g), while pulp had the highest values (~600 mg/100 g). However, papaya skin presented higher total phenolic content (~560 mg GAE/100 g) and flavonoids (~1000 mg QE/100 g) than pulp and seeds. Also, papaya skin showed the highest values followed by pulp and seeds with TEAC, FRAP and DPPH. Papaya skin had higher carotenoids and α-tocopherol (~1500 µg/100 g and ~4000 µg/100 g, respectively) content than pulp and seeds. BC content in each byproduct varied in all RS. Therefore, among the papaya byproducts, skin represents a good source of BC with good antioxidant properties, which may be used to extract them for its incorporation in functional foods depending on RS
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