28 research outputs found
The impact of talent management practices on employee retention: The moderator effect of leader-member exchange and role modeling
Organizations are undergoing serious difficulties to retain talent. Authors argue that Talent Management (TM) practices create beneficial outcomes for individuals and organizations. However, there is no research on the leadersâ role in the functioning of these practices. This study examines how LMX and role modeling influence the impact that TM practices have on employeesâ trust in their organizations and retention. The analysis of two questionnaires (Nt1=175; Nt2=107) indicated that TM only reduced turnover intentions, via an increase in trust in the organization, when role modeling was high and not when it was low. Therefore, we can say that leaders are crucial in the TM context, and in sustaining a competitive advantage for organizations
PrĂĄticas artĂsticas no ensino bĂĄsico e secundĂĄrio
A educação pela arte faz-se atravĂ©s dos seus materiais, da sua operação, da transformação das matĂ©rias em ideias novas, em novas coisas. No seu sucesso estĂĄ implicada uma literacia, uma capacidade interpretativa, ou crĂtica, sobre a semiosfera cada vez mais povoada, saturada de mensagens parasitĂĄrias. A educação implica uma leitura do mundo (Paulo Freire), que se projeta na interpretação de todas as camadas de expressĂŁo contemporĂąnea, muitas vezes massificada, por vezes ainda identitĂĄria e significativa. Fala-se aqui de valorizar a identidade, exercer a pedagogia da diferença atravĂ©s de uma capacidade problematizadora. No seu contexto, podem exercer-se pedagogias que exploram a visĂŁo crĂtica do artista em interação com a escola, o artista em residĂȘncia, no movimento A/ R/ Tography. Ou tambĂ©m exercer-se uma pedagogia triangular, centrando a arte, o contexto, a produção e a sua leitura como uma metodologia (Ana Mae Barbosa). O contexto contemporĂąneo Ă© pĂłs digital, os conteĂșdos nĂŁo pesam nos suportes, e transmitem-se por âdentes azuisâ ou redes com muitos Gs (G de Geração sem peso que sucede ao peso da aceleração gravĂtica). Neste campo pode delinear-se uma metodologia que alicerça o projeto ancorado nos estudos crĂticos sobre Cultura Visual (Fernando HernĂĄndez). Digamos que as prĂĄticas pedagĂłgicas se cruzam em diversas direçÔes, tacteando eficĂĄcias, expressĂ”es, capacidades, inovação. O contexto Ă© cada vez mais voraz: a pele da cultura gosta de massagens (Kerkhove; McLuhan). A MatĂ©ria-Prima de que se fala nesta revista Ă© aquela que devolve ao seu lugar um ponto crĂtico da pĂłs modernidade: o do significante. Os sintagmas sĂŁo sempre processos, e neles se formam as subjectividades, ou seja, as identidades: no desenrolar do ser, onde se produz verdadeiramente o sentido, bem junto do aqui-e-agora onde estĂĄ a MatĂ©ria-Prima (Foucault).info:eu-repo/semantics/publishedVersio
SĂndrome do coração PĂłs-feriado: pacientes acometidos por arritmia cardĂaca em detrimento do consumo exagerado de ĂĄlcool: Post Holiday coração Syndrome: patients suffered by cardiac arrhythmia to the detriment of exaggerated alcohol consumption
INTRODUĂĂO: O ĂĄlcool Ă© conhecido por beneficiar o sistema cardiovascular com a ativação do sistema fibrinolĂtico, redução da agregação de plaquetas e aperfeiçoamento do perfil lipĂdico, entre outros mecanismos, quando consumido em doses moderadas. Todavia, seu uso de maneira abusiva culmina em patologias graves que podem evoluir para a morte, como a hipertensĂŁo arterial, a cardiomiopatia alcoĂłlica, a arritmia cardĂaca e atĂ© a âSĂndrome do Coração PĂłs Feriadoâ ou do inglĂȘs, âHoliday Heart Syndromeâ. OBJETIVOS: O presente estudo tem como objetivo delinear sobre a SĂndrome do Coração PĂłs Feriado, transpassando por suas caracterĂsticas clĂnicas, repercussĂ”es eletrofisiolĂłgicas, diagnĂłstico e manejo terapĂȘutico. MATERIAIS E MĂTODOS: Dessa forma, o presente trabalho realizou uma revisĂŁo sistemĂĄtica qualitativa, realizado no perĂodo entre julho e agosto de 2022, atravĂ©s de artigos das bases de dados Biblioteca Virtual em SaĂșde (BVS) e United States National Library of Medicine (PubMed). RESULTADOS E DISCUSSĂO: A interação do ĂĄlcool no organismo estĂĄ diretamente relacionada com o sistema nervoso autĂŽnomo do indivĂduo, gerando um estado de desequilĂbrio autonĂŽmico, assim hĂĄ alteraçÔes elĂ©tricas, como acrĂ©scimo da frequĂȘncia cardĂaca, gerando um estado de taquicardia. A principal patologia encontrada em questĂŁo foi a taquicardia sinusal, sendo um tipo de arritmia e por conseguinte, notou-se a presença da fibrilação atrial, sendo o excesso no consumo de etanol Ă© causador de aproximadamente 67% dos casos de emergĂȘncias desta Ășltima enfermidade. CONCLUSĂO: Portanto, com base na literatura analisada, observou-se que a ingestĂŁo alcoĂłlica aguda age retardando o sistema de condução cardĂaco, atua no encurtamento do perĂodo refratĂĄrio e o aumento da atividade simpĂĄtica, alĂ©m de aumentar os nĂveis de catecolaminas circulantes. Por fim, tambĂ©m se evidenciou uma associação entre ĂĄlcool e fatores de risco, principalmente hipertensĂŁo e obesidade e essas patologias aumentam os episĂłdios de fibrilação atrial
ATLANTIC EPIPHYTES: a data set of vascular and non-vascular epiphyte plants and lichens from the Atlantic Forest
Epiphytes are hyper-diverse and one of the frequently undervalued life forms in plant surveys and biodiversity inventories. Epiphytes of the Atlantic Forest, one of the most endangered ecosystems in the world, have high endemism and radiated recently in the Pliocene. We aimed to (1) compile an extensive Atlantic Forest data set on vascular, non-vascular plants (including hemiepiphytes), and lichen epiphyte species occurrence and abundance; (2) describe the epiphyte distribution in the Atlantic Forest, in order to indicate future sampling efforts. Our work presents the first epiphyte data set with information on abundance and occurrence of epiphyte phorophyte species. All data compiled here come from three main sources provided by the authors: published sources (comprising peer-reviewed articles, books, and theses), unpublished data, and herbarium data. We compiled a data set composed of 2,095 species, from 89,270 holo/hemiepiphyte records, in the Atlantic Forest of Brazil, Argentina, Paraguay, and Uruguay, recorded from 1824 to early 2018. Most of the records were from qualitative data (occurrence only, 88%), well distributed throughout the Atlantic Forest. For quantitative records, the most common sampling method was individual trees (71%), followed by plot sampling (19%), and transect sampling (10%). Angiosperms (81%) were the most frequently registered group, and Bromeliaceae and Orchidaceae were the families with the greatest number of records (27,272 and 21,945, respectively). Ferns and Lycophytes presented fewer records than Angiosperms, and Polypodiaceae were the most recorded family, and more concentrated in the Southern and Southeastern regions. Data on non-vascular plants and lichens were scarce, with a few disjunct records concentrated in the Northeastern region of the Atlantic Forest. For all non-vascular plant records, Lejeuneaceae, a family of liverworts, was the most recorded family. We hope that our effort to organize scattered epiphyte data help advance the knowledge of epiphyte ecology, as well as our understanding of macroecological and biogeographical patterns in the Atlantic Forest. No copyright restrictions are associated with the data set. Please cite this Ecology Data Paper if the data are used in publication and teaching events. © 2019 The Authors. Ecology © 2019 The Ecological Society of Americ
COVID-19 symptoms at hospital admission vary with age and sex: results from the ISARIC prospective multinational observational study
Background:
The ISARIC prospective multinational observational study is the largest cohort of hospitalized patients with COVID-19. We present relationships of age, sex, and nationality to presenting symptoms.
Methods:
International, prospective observational study of 60â109 hospitalized symptomatic patients with laboratory-confirmed COVID-19 recruited from 43 countries between 30 January and 3 August 2020. Logistic regression was performed to evaluate relationships of age and sex to published COVID-19 case definitions and the most commonly reported symptoms.
Results:
âTypicalâ symptoms of fever (69%), cough (68%) and shortness of breath (66%) were the most commonly reported. 92% of patients experienced at least one of these. Prevalence of typical symptoms was greatest in 30- to 60-year-olds (respectively 80, 79, 69%; at least one 95%). They were reported less frequently in children (â€â18 years: 69, 48, 23; 85%), older adults (â„â70 years: 61, 62, 65; 90%), and women (66, 66, 64; 90%; vs. men 71, 70, 67; 93%, each Pâ<â0.001). The most common atypical presentations under 60 years of age were nausea and vomiting and abdominal pain, and over 60 years was confusion. Regression models showed significant differences in symptoms with sex, age and country.
Interpretation:
This international collaboration has allowed us to report reliable symptom data from the largest cohort of patients admitted to hospital with COVID-19. Adults over 60 and children admitted to hospital with COVID-19 are less likely to present with typical symptoms. Nausea and vomiting are common atypical presentations under 30 years. Confusion is a frequent atypical presentation of COVID-19 in adults over 60 years. Women are less likely to experience typical symptoms than men
Raising awareness of new psychoactive substances: chemical analysis and in vitro toxicity screening of âlegal highâ packages containing synthetic cathinones
The worldâs status quo on recreational drugs has dramatically changed in recent years due to the rapid emergence of new psychoactive substances (NPS), represented by new narcotic or psychotropic drugs, in pure form or in preparation, which are not controlled by international conventions, but that may pose a public health threat com-
parable with that posed by substances listed in these conventions. These NPS, also known as âlegal highsâ or âsmartdrugsâ, are typically sold via Internet or âsmartshopsâ as legal alternatives to controlled substances, being announced as âbath saltsâ and âplant feedersâ and is often sought after for consumption especially among young people. Although NPS have the biased reputation of being safe, the vast majority has hitherto not been tested and several fatal cases have been reported, namely for synthetic cathinones, with pathological patterns comparable with amphetamines. Additionally, the unprecedented speed of appearance and distribution of the NPS worldwide brings technical difficulties in the development of analytical procedures and risk
assessment in real time. In this study, 27 products commercialized as âplant feedersâ were chemically characterized by gas chromatographyâmass spectrometry and nuclear magnetic resonance spectroscopy. It was also evaluated, for the first time, the in vitro hepatotoxic effects of individual synthetic cathinones, namely methylone, pentedrone, 4-methylethcathinone (4-MEC) and 3,4-methylenedioxypyrovalerone (MDPV). Two commercial mixtures (âBloomâ and âBlowâ) containing mainly cathinone derivatives were also tested, and 3,4-methylenedioxymethamphetamine (MDMA) was used as the reference drug. The study allowed the identification of 19 compounds, showing that synthetic cathinones are the main active compounds present in these products. Qualitative and quantitative variability was found in products sold with the same trade name in matching or different âsmartshopsâ. In the toxicity studies performed in primary cultured rat hepatocytes, pentedrone and MDPV proved to be the most potent individual agents, with EC50 values of 0.664 and 0.742 mM, respectively, followed by MDMA (EC50 = 0.754 mM). 4-MEC and methylone were the least potent substances, with EC50 values significantly higher (1.29 and 1.18 mM, respectively; p < 0.05 vs. MDMA). âBloomâ and âBlowâ showed hepatotoxic effects similar to MDMA (EC50 = 0.788 and 0.870 mM,
respectively), with cathinones present in these mixtures contributing additively to the overall toxicological effect. Our results show a miscellany of psychoactive compounds present in âlegal highâ products with evident hepatotoxic effects. These data contribute to increase the awareness on the real composition of âlegal highâ packages and unveil the health risks posed by NPS.info:eu-repo/semantics/publishedVersio
Alunos da educação båsica visitam à universidade: instrumento para a aprendizagem da educação ambiental na extensão
In this work, we demonstrate the importance of activities given in university extension capable of promoting the learning of citizenship and environmental education. We emphasize, as well, two visits of 180 students of 6th student grade of a public school to the Faculty of Agricultural Sciences and Veterinary - FCAV - UNESP, which were generating such learning. We analyze the representations of agriculture and nature of these students generated and their interrelationships to carry out these inspections and the practice of environmental education. The dialogue and reflection on the importance of activities of this nature - able to bring the university and the community - have made the members of this extension project realized the possible connection between teaching, research and extension. This experience forms part of the extension project "Environmental Education, Agriculture and Food Security in Basic Education" (Cultivaeco Project) that is supported by Proex since 2009, with the acquisition of resources and scholarships.Neste trabalho, demonstramos a importĂąncia de atividades dadas na extensĂŁo universitĂĄria capazes de promover a aprendizagem da cidadania e da educação ambiental. Destacamos, assim, duas visitas de 180 estudantes de 6ÂȘ. sĂ©rie de uma escola pĂșblica Ă Faculdade de CiĂȘncias AgrĂĄrias e VeterinĂĄrias â FCAV â UNESP, as quais foram geradoras dessa aprendizagem. Analisamos as representaçÔes de agricultura e natureza desses estudantes geradas e suas inter-relaçÔes com a realização dessas visitas e a prĂĄtica da educação ambiental. O diĂĄlogo e a reflexĂŁo sobre a importĂąncia de atividades dessa natureza â capazes de aproximar a universidade e a comunidade â fizeram com que os integrantes desse projeto de extensĂŁo percebessem a possĂvel articulação entre o ensino, a pesquisa e a extensĂŁo. Essa experiĂȘncia se insere no projeto de extensĂŁo âEducação Ambiental, Agricultura e Segurança Alimentar na Educação BĂĄsicaâ (Projeto Cultivaeco) que tem o apoio da Proex desde 2009, com a obtenção de recursos e bolsas
Prospecting in silico antibacterial activity of a peptide from trypsin inhibitor isolated from tamarind seed
AbstractBacterial infections have become a global concern, stimulating the growing demand for natural and biologically safe therapeutic agents with antibacterial action. This study was evaluated the genotoxicity of the trypsin inhibitor isolated from tamarind seeds (TTI) and the antibacterial effect of TTI theoric model, number 56, and conformation number 287 (TTIp 56/287) and derived peptides in silico. TTI (0.3 and 0.6âmg.mLâ1) did not cause genotoxicity in cells (pâ>â0.05). In silico, a greater interaction of TTIp 56/287 with the Gram-positive membrane (GP) was observed, with an interaction potential energy (IPE) of â1094.97âkcal.molâ1. In the TTIp 56/287-GP interaction, the Arginine, Threonine (Thr), and Lysine residues presented lower IPE. In molecular dynamics (MD), Peptidotrychyme59 (TVSQTPIDIPIGLPVR) showed an IPE of â518.08âkcal.molâ1 with the membrane of GP bacteria, and the Thr and Arginine residues showed the greater IPE. The results highlight new perspectives on TTI and its derived peptides antibacterial activity
Bullying: desafĂos para a convivencia Ă©tica no combate ao assedio
Este artigo registra parte dos resultados de uma atividade de extensĂŁo universitĂĄria realizada junto a trabalhadores na educação e saĂșde do municĂpio de HumaitĂĄ, sul do Estado do Amazonas, onde foram realizadas atividades de reflexĂŁo-ação acerca da convivĂȘncia Ă©tica e democrĂĄtica. EstĂĄ organizado em duas partes: a primeira destaca aspectos conceituais e filosĂłficos acerca do tema; a segunda parte apresenta os resultados da intervenção em contextos da educação e da saĂșde