7,188 research outputs found
Kernel arquitecture for CAD/CAM in shipbuilding enviroments
The capabilities of complex software products such as CAD/CAM systems are strongly supported by basic information technologies related with data management, visualization, communication, geometry modeling and others related with the development process. These basic information technologies are involved in a continuous evolution process, but over recent years this evolution has been dramatic. The main reason for this has been that new hardware capabilities (including graphic cards) are available at very low cost, but also a contributing factor has been the evolution of the prices of basic software. To take advantage of these new features, the existing CAD/CAM systems must undergo a complete and drastic redesign. This process is complicated but strategic for the future evolution of a system. There are several examples in the market of how a bad decision has lead to a cul-de-sac (both technically and commercially). This paper describes what the authors consider are the basic architectural components of a kernel for a CAD/CAM system oriented to shipbuilding. The proposed solution is a combination of in-house developed frameworks together with commercial products that are accepted as standard components. The proportion of in-house frameworks within this combination of products is a key factor, especially when considering CAD/CAM systems oriented to shipbuilding. General-purpose CAD/CAM systems are mainly oriented to the mechanical CAD market. For this reason several basic products exist devoted to geometry modelling in this context. But these basic products are not well suited to deal with the very specific geometry modelling requirements of a CAD/CAM system oriented to shipbuilding. The complexity of the ship model, the different model requirements through its short and changing life cycle and the many different disciplines involved in the process are reasons for this inadequacy. Apart from these basic frameworks, specific shipbuilding frameworks are also required. This second layer is built over the basic technology components mentioned above. This paper describes in detail the technological frameworks which have been used to develop the latest FORAN version.Postprint (published version
Improving the surface finish of concave and convex surfaces using a ball burnishing process
The ball burnishing process is done to improve the surface finish of workpieces that have been previously machined. In this article we present
the results of tests performed with this process that was applied to workpieces with a convex or concave surface of two different materials:
aluminum A92017 and steel G10380. An experiment to do the tests was designed. The results of measurements of surface roughness are presented
in this paper as well. These results are compared to those measured in the workpieces before being burnished. After that conclusions are drawn
about the improvement of surface roughness applied to the workpieces through the ball burnishing process. The main innovation of this paper is
that we work with concave and convex geometries. We also obtain a table of recomended parameter values for the process
Las Musas y la Inspiración del poeta: a propósito de «El Parnaso» de Nicolas Poussin, Museo del Prado.
Sin resume
IPSC differentiation into ependymal progenitors to treat ventricular damage during hydrocephalus
Introduction: During both obstructive congenital hydrocephalus and post-hemorrhagic hydrocephalus additional pathological events are intimately associated with their ethiology: a) a detrimental inflammatory response; b) severe damage of the underlying periventricular nervous tissue, including white matter, and c). Therapeutic approaches have been directed to overcome a) and b), however recovery of damaged neuroepithelium/ependyma is, in our present, an important therapeutic gap.
Methods: Human and mouse induced pluripotent stem cells (iPSC) have been artificially differented into ependymal progenitors. Intracerebroventricular (ICV) injections of iPCS are performed ex vivo and in vivo in the damaged ventricular wall. Their integration and differentiation has been studied by immunohistochemistry and histopathological analysis.
Results: Mice and human ependymal progenitors are able to integrate and differentiate into ependyma in damaged ventricular wall. Stage of ependymal differentiation by the time of the injection defined different degrees of integration.
Conclusions: IPSC appear to be a good ependymal progenitor source with no ethical controversy associated.RyC 2014-16980
Universidad de Málaga. Campus de Excelencia Internacional Andalucía Tec
Negation with participles
Source at https://www.linguisticanalysis.com/.Languages differ with respect to the possibility of introducing a
negative operator between an auxiliary verb and a participle inside
aspectual periphrases; whereas Lithuanian perfect forms allow
negation in that position, Spanish rejects it. The goal of this paper
is to offer an analysis of this contrast, which contributes to our understanding of low negation in the clausal domain. We propose that
when negation follows an auxiliary verb, it is merged in a Polarity
Phrase placed below AspP within the event domain. This low negation gives rise to an inhibited event reading, which expresses that the
subject refrains himself from initiating the event. We argue that the
possibility of introducing a negative operator between a participle
and an auxiliary is conditional upon the hierarchical level in which
the relevant participle is formed. We show that in Spanish, this verbal
form is built above Asp and as a result, low negation would intervene
between the verbal stem and the participial morphology. On the
contrary, in Lithuanian, participles are formed in the event domain,
below AspP. Low negation can, thus, be added without breaking the
internal make up of the participle
Los primeros modelos europeos de industrialización farmacéutica: bases para su caracterización
Las pautas que definen el proceso de industrialización en Europa no son uniformes; sus diferencias hunden sus raíces, como acertadamente señaló el sociólogo alemán Max Weber a comienzos del siglo XX1, en el ‘espíritu del capitalismo’ que define a los pueblos del centro y norte de Europa, frente al talante ‘tradicionalista’ de los europeos del Mediterráneo; no es éste el lugar en el que discutir la importancia de las ideas protestantes en el desarrollo de la ‘revolución agraria’ ni el impacto de ésta en la ‘revolución industrial’ que habría de iniciarse en la Inglaterra del siglo XVIII2; pero es indudable la diferente mentalidad -y la distinta renta per capita- con que los países del centro y norte de Europa, la ‘Europa protestante’, abordan la ‘revolución industrial’ frente a los territorios bañados por el Mediterráneo, integrados éstos en el concepto que Max Weber definió como la ‘Europa católica’.
La génesis de la industria farmacéutica europea no es ajena a esta situación de conjunto; si bien en ella, junto a los factores sociales, económicos o políticos definidores de cualquier otra actividad industrial, deben considerarse también otros, científicos y tecnológicos, que le son característicos. El desarrollo de la industria farmacéutica no parece poder explicarse sólo en términos socio-económicos, en él los aspectos estrictamente técnicos, como la aparición de los principios activos de síntesis y semi-síntesis o el desarrollo de nuevas formas farmacéuticas, más adaptables a los requerimientos de elaboración al por mayor exigidos por la nueva industria del medicamento, cobran una singular importancia; en nuestra opinión, se convierten en agentes decisivos de la evolución de este sector industrial y ofrecen elementos suficientes para proponer, basándose exclusivamente en ellos, una tipificación del proceso de industrialización
Real Academia Médica matritense y expediciones botánicas ilustradas. Una conexión farmaco-terapéutica
Con este trabajo se pretende realizar un estudio de la repercusión que tuvieron las expediciones botánicas ilustradas en las discusiones de carácter farmacológico suscitadas en el seno de la Real Academia de Medicina de Madrid. Las aportaciones al conocimiento de la naturaleza vegetal americana, desde el punto de vista fármaceterapéutico, vinieron, principalmente, de la mano de los integrantes de la "Oficina de la Flora Americana", José Pavón y, sobre todo, Hipólito Ruiz. Las contribuciones a este campo realizadas por otros expedicionarios fueron más escasas, prácticamente reducidas a los estudios de los botánicos desplazados a Nueva España : Vicente Cervantes, Martín Sessé y José Mariano Mociño
Carex elata All. ssp elata, new for Algarve in the lower Guadiana basin
Carex elata All. ssp elata novedad para el Algarve en la cuenca del rio Guadian
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