Multipactor radiation analysis within a waveguide region based on a frequency-domain representation of the dynamics of charged particles

A technique for the accurate computation of the electromagnetic fields radiated by a charged particle moving within a parallel-plate waveguide is presented. Based on a transformation of the time-varying current density of the particle into a time-harmonic current density, this technique allows the evaluation of the radiated electromagnetic fields both in the frequency and time domains, as well as in the near- and far-field regions. For this purpose, several accelerated versions of the parallel-plate Green’s function in the frequency domain have been considered. The theory has been successfully applied to the multipactor discharge occurring within a two metal-plates region. The proposed formulation has been tested with a particle-in-cell code based on the finite- difference time-domain method, obtaining good agreement.The authors would like to thank ESA/ESTEC for having funded this research activity through the Contract “RF Breakdown in Multicarrier Systems” ͑Contract No. 19918/06/NL/GLC͒

Dataset of the sperm proteome of stallions with different motility

This paper provides a detailed set of data on how the stal-lion sperm proteome differs among stallions with different sperm motilities, although within normal ranges. Findings distinguish proteins that may help to identify stallions of su-perior sperm motility. Sperm proteins were analyzed using a UHPLC/MS/MS system comprising of an Agilent 1290 in-finity series UHPLC coupled to an Agilent 6550 Q-TOF mass spectrometer (Agilent Technologies, Santa Clara, CA, USA). These data can be used to disclose potential targets to iden-tify good sperm samples and to study specific pathways in-volved in the regulation of sperm motility. This data article is linked to the paper "Proteins involved in mitochondrial metabolic functions and fertilization predominate in stallions with better motility Journal of Proteomics 247:104335 doi: 10.1016/j.jprot.2021.104335".(c) 2022 The Author(s). Published by Elsevier Inc.This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/

Quantitative trait loci for resistance to trichostrongylid infection in Spanish Churra sheep

This is an Open Access article distributed under the terms of the Creative Commons Attribution Licens

Clinical infections by herpesviruses in patients treated with valproic acid: A nested case-control study in the Spanish Primary Care Database, BIFAP

The objective of this study is to evaluate the risk of clinical infections by herpesviruses in patients exposed to valproic acid (VPA).We performed a case-control study nested in a primary cohort selected from the Spanish primary care population-based research database BIFAP (Base de datos para la Investigación Farmacoepidemiológica en Atención Primaria) over the period 2001–2015. The events of interest were those diseases caused by any herpesviruses known to infect humans. For each case, up to 10 controls per case matched by age, gender, and calendar date were randomly selected. A conditional logistic regression was used to compute adjusted odds ratios (OR) and their 95% confidence intervals (95% CI). Current use of VPA was associated with a trend towards a reduced risk of clinical infections by herpesviruses as compared with non-users (OR 0.84; CI 95% 0.7–1.0; p = 0.057). Among current users, a trend to a decreased risk with treatment durations longer than 90 days was also observed. The results show a trend to a reduced risk of clinical infection by herpesviruses in patients exposed to VPA. These results are consistent with those in vitro studies showing that, in cultured cells, VPA can inhibit the production of the infectious progeny of herpesviruses. This study also shows the efficient use of electronic healthcare records for clinical exploratory research studie

An analytical model to evaluate the radiated power spectrum of a multipactor discharge in a parallel-plate region

This paper is aimed at studying the electromagnetic radiation pattern of a multipactor discharge occurring in a parallel-plate waveguide. The proposed method is based on the Fourier expansion of the multipactor current in terms of timeharmonic currents radiating in the parallel-plate region. Classical radiation theory combined with the frequency domain Green’s function of the problem allows the calculation of both the electric and the magnetic radiated fields. A novel analytical formula for the total radiated power of each multipactor harmonic has been derived. This formula is suitable for predicting multipactor with the third-harmonic technique. The proposed formulation has been successfully tested with a particle-in-cell code

La protección de los derechos fundamentales de las personas LGTBI

Producción CientíficaEl presente volumen, realizado en el marco del Proyecto estatal "España ante Europa: retos nacionales en materia de derechos fundamentales" (DER2016-75993-P), se articula en torno a dos partes bien diferenciadas. En la primera se examina la protección de los derechos fundamentales de las personas LGTBI en perspectiva internacional y comparada. Comprende un estudio de Ignacio Álvarez Rodríguez sobre el papel desempeñado por la ONU a este respecto; otro de José Díaz Lafuente acerca de los avances habidos en el seno de la UE en este terreno; y un tercero sobre el Consejo de Europa, a cargo de Francisco Ruiz-Risueño Montoya, en el que se disecciona críticamente la muy relevante jurisprudencia del Tribunal Europeo de Derechos Humanos recaída sobre la materia. Esta primera parte se completa con un estudio comparado de Anna Lorenzetti sobre la situación jurídica de las personas LGTBI en diversos Estados europeos. En la segunda parte de la obra se analizan temas específicos que presentan especial interés para el colectivo LGTBI. María Díaz Crego aborda la discriminación por orientación sexual; Miguel Ángel Presno Libera se ocupa del discurso del odio contra las minorías sexuales: Pilar Benavente examina el registro y la filiación de parejas LGTBI; Francisco Javier Matia Portilla se pregunta si sería conveniente regular la gestación subrogada en nuestro país; y finalmente Antonio Arroyo Gil concluye con una reflexión jurídica sobre la intersexualidad.Departamento de Derecho Constitucional, Procesal y Eclesiástico del EstadoMinisterio de Economía, Industria y Competitividad (DER2016-75993-P

La integración del conocimiento sobre la Cordillera Cantábrica: hacia un observatorio inter-autonómico del cambio global

Producción CientíficaLa Cordillera Cantábrica presenta una serie de singularidades que le convierten en un excelente enclave para el seguimiento de los efectos del cambio global. Este estudio analiza la necesidad de generar un observatorio inter-autonómico del cambio global, que permitiría integrar el conocimiento actual sobre estas montañas y determinar las prioridades en la generación de nuevo conocimiento. Para cumplir este objetivo, se presentan dos aproximaciones complementarias. La primera consiste en la revisión de la literatura científica publicada sobre la Cordillera Cantábrica y su comparación con otros enclaves geográficos de la Península Ibérica. La segunda consiste en la síntesis de información de un seminario titulado “La Cordillera Cantábrica como Centinela de los Efectos del Cambio Global”, celebrado en Santander en agosto de 2015. El análisis bibliográfico muestra que el número de publicaciones científicas sobre la Cordillera Cantábrica es similar al de otros enclaves geográficos de la Península Ibérica, pero con menor riqueza de disciplinas. La producción científica está dominada por los centros de investigación más próximos y tiene una alta participación internacional. Las conclusiones del seminario evidencian que este sistema es un candidato ideal para el seguimiento de los efectos del cambio global sobre multitud de elementos biofísicos. Se considera que la generación de un seminario permanente, junto con la consolidación de las redes de seguimiento actuales, la coordinación de nuevos trabajos, y la mejora de la comunicación entre administraciones y comunidad científico-técnica son elementos esenciales en la futura generación de un observatorio del cambio global en la Cordillera Cantábrica

Statement of the Spanish Interdisciplinary Cardiovascular Prevention Committee (CEIPC ) on the 2012 European Cardiovascular Prevention Guidelines

Las guías europeas de prevención cardiovascular contemplan dos sistemas de evaluación de la evidencia (SEC y GRADE) y recomiendan combinar las estrategias poblacional y de alto riesgo, interviniendo en todas las etapas de la vida, con la dieta como piedra angular de la prevención. La valoración del RCV incorpora los niveles de HDL y los factores psicosociales, una categoría de muy alto riesgo y el concepto edad-riesgo. Se recomienda e luso de métodos cognitivo-conductuales (entrevistamotivadora, intervenciones psicológicas), aplicados por profesionales sanitarios, con la participación de familiares de los pacientes, para contrarrestar el estrés psicosocial y reducir el RCV mediante dietas saludables, entrenamiento físico, abandono del tabaco y cumplimiento terapéutico. También se requieren medidas de salud pública, como la prohibición de fumar en lugares públicos o eliminar los ácidos grasos trans de la cadena alimentaria. Otras novedades consisten en desestimar el tratamiento antiagregante en prevención primaria y la recomendación de mantener la PA dentro del rango13-139/80-85 mmHg en pacientes diabéticos o con RCV alto. Se destaca el bajo cumplimiento terapéutico observado, porque influye en el pronóstico de los pacientes y en los costes sanitarios. Para mejorar la prevención cardiovascular se precisa una verdadera alianza entre políticos, administraciones, asociaciones científicas y profesionales de la salud, fundaciones de salud, asociaciones de consumidores, pacientes y sus familias, que impulse las estrategias poblacional e individual, mediante el uso de toda la evidencia científica disponible, desde ensayos clínicos hasta estudios observacionales y modelo matemáticos para evaluar intervenciones a nivel poblacional, incluyendo análisis de coste-efectividadBased on the two main frameworks for evaluating scientific evidence—SEC and GRADE—European cardiovascular prevention guidelines recommend interventions across all life stages using a combination of population-based and high-risk strategies with diet as the cornerstone of prevention. The evaluation of cardiovascular risk (CVR) incorporates HDL level and psycho-social factors, a very high risk category, and the concept of age-risk. They also recommend cognitive-behavioural methods (e.g.,motivational interviewing, psychological interventions, led by health professionals and with the participation of the patient’s family, to counterbalance psychosocial stress and reduce CVR through the institution of positive habits such as a healthy diet, physical activity, smoking cessation, and adherence to treatment. Additionally, public health interventions—such as smoking ban in public areas or the elimination of trans fatty acids from the food chain—are also essential. Other innovations include abandoning antiplatelet therapy in primary prevention and the recommendation of maintaining blood pressure (BP) within the1 30-139/80-85 mmHg range in diabetic patients and individuals with high CVR. Finally ,due to the significant impact on patient progress and medical costs, special emphasisis given to the low therapeutic adherence levels observed . In sum ,improving cardiovascular prevention requires a true partnership among the political class, public administrations, scientific and professional associations, health foundations, consumer associations, patients and their families. Such partnership would promote population-based and individual strategies by taking advantage o the broad spectrum of scientific evidence available, from clinical trials to observational studies and mathematical models to evaluate population-based interventions, including cost-effectiveness analyse

Altered brain rhythms and functional network disruptions involved in patients with generalized fixation-off epilepsy

Fixation-off sensitivity (FOS) denotes the forms of epilepsy elicited by elimination of fixation. FOS-IGE patients are rare cases [1]. In a previous work [2] we showed that two FOS-IGE patients had different altered EEG rhythms when closing eyes; only beta band was altered in patient 1 while theta, alpha and beta were altered in patient 2. In the present work, we explain the relationship between the altered brain rhythms in these patients and the disruption in functional brain networks