Maximum Likelihood Analysis of Clusters of Ultra-High Energy Cosmic Rays

We present a numerical code designed to conduct a likelihood analysis for clusters of nucleons above 10**19 eV originating from discrete astrophysical sources such as powerful radio galaxies, gamma-ray bursts or topological defects. The code simulates the propagation of nucleons in a large-scale magnetic field and constructs the likelihood of a given observed event cluster as a function of the average time delay due to deflection in the magnetic field, the source activity time scale, the total fluence of the source, and the power law index of the particle injection spectrum. Other parameters such as the coherence length and the power spectrum of the magnetic field are also considered. We apply it to the three pairs of events above 4X10**19 eV recently reported by the Akeno Giant Air Shower Array (AGASA) experiment, assuming that these pairs were caused by nucleon primaries which originated from a common source. Although current data are too sparse to fully constrain each of the parameters considered, and/or to discriminate models of the origin of ultra-high energy cosmic rays, several tendencies are indicated. If the clustering suggested by AGASA is real, next generation experiments with their increased exposure should detect more than 10 particles per source over a few years and our method will put strong constraints on both the large-scale magnetic field parameters and the nature of these sources.Comment: 11 latex pages, 8 postscript figures included, uses revtex.sty in two-column format and epsf.sty. Submitted to Physical Review

Natural Inflation: Particle Physics Models, Power Law Spectra for Large Scale Structure, and Constraints from COBE

A pseudo-Nambu-Goldstone boson, with a potential of the form $V(\phi) = \Lambda^4[1 \pm \cos(\phi/f)], naturally gives rise to inflation if$f \sim M_{Pl}$and$\Lambda \sim M_{GUT}$. We show how this can arise in technicolor-like and superstring models, and work out an explicit string example in the context of multiple gaugino condensation models. We study the cosmology of this model in detail, and find that sufficient reheating to ensure that baryogenesis can take place requires$f > 0.3 M_{Pl}$. The primordial density fluctuation spectrum generated is a non-scale-invariant power law,$P(k) \propto k^{n_s}$, with$n_s \simeq 1 - (M^2_{Pl}/8\pi f^2)$, leading to more power on large length scales than the$n_s = 1$Harrison-Zeldovich spectrum. The standard CDM model with$0 \la n_s \la 0.6-0.7$could in principle explain the large-scale clustering observed in the APM and IRAS galaxy surveys as well as large-scale flows, but the COBE microwave anisotropy implies such low amplitudes (or high bias factors,$b>2$) for these CDM models that galaxy formation occurs too late to be viable; combining COBE with sufficiently early galaxy formation or the large-scale flows leads to$n_s >0.6$, or$f > 0.3 M_{Pl}$as well. For extended and power law inflation models, this constraint is even tighter,$n_s > 0.7$; combined with other bounds on large bubbles in extended inflation, this leaves little room for most extended models.Comment: 42 pages, (12 figures not included but available from the authors

Refined Metallicity Indices for M Dwarfs Using the SLoWPoKES Catalog of Wide, Low-mass Binaries

We report the results from spectroscopic observations of 113 ultra-wide, low-mass binary systems, composed largely of M0--M3 dwarfs, from the SLoWPoKES catalog of common proper motion pairs identified in the Sloan Digital Sky Survey. Radial velocities of each binary member were used to confirm that they are co-moving and, consequently, to further validate the high fidelity of the SLoWPoKES catalog. Ten stars appear to be spectroscopic binaries based on broad or split spectral features, supporting previous findings that wide binaries are likely to be hierarchical systems. We measured the H{\alpha} equivalent width of the stars in our sample and found that components of 81% of the observed pairs has similar H{\alpha} levels. The difference in H{\alpha} equivalent width amongst components with similar masses was smaller than the range of H{\alpha} variability for individual objects. We confirm that the Lepine et al. {\zeta}(CaH2+CaH3, TiO5) index traces iso-metallicity loci for most of our sample of M dwarfs. However, we find a small systematic bias in {\zeta}, especially in the early-type M dwarfs. We use our sample to recalibrate the definition of {\zeta}. While representing a small change in the definition, the new {\zeta} is a significantly better predictor of iso-metallicity for the higher mass M dwarfs.Comment: Accepted for publication in AJ, 10 page

Peer navigation improves diagnostic follow-up after breast cancer screening among Korean American women: results of a randomized trial

To test an intervention to increase adherence to diagnostic follow-up tests among Asian American women. Korean American women who were referred for a diagnostic follow-up test (mainly diagnostic mammograms) and who had missed their follow-up appointment were eligible to participate in the study. Women from two clinics (n = 176) were randomly allocated to a usual care control arm or a peer navigator intervention arm. A 20-min telephone survey was administered to women in both study arms six months after they were identified to assess demographic and socio-economic characteristics and the primary outcome, self-reported completion of the recommended follow-up exam. Among women who completed the survey at six-month follow-up, self-reported completion of follow-up procedures was 97% in the intervention arm and 67% in the control arm (p < 0.001). Based on an intent-to-treat analysis of all women who were randomized and an assumption of no completion of follow-up exam for women with missing outcome data, self-reported completion of follow-up was 61% in the intervention arm and 46% in the usual care control arm (p < 0.069). Our results suggest that a peer navigator intervention to assist Korean American women to obtain follow-up diagnostic tests after an abnormal breast cancer screening test is efficacious

Dynamics and constraints of the dissipative Liouville cosmology

In this article we investigate the properties of the FLRW flat cosmological models in which the cosmic expansion of the Universe is affected by a dilaton dark energy (Liouville scenario). In particular, we perform a detailed study of these models in the light of the latest cosmological data, which serves to illustrate the phenomenological viability of the new dark energy paradigm as a serious alternative to the traditional scalar field approaches. By performing a joint likelihood analysis of the recent supernovae type Ia data (SNIa), the differential ages of passively evolving galaxies, and the Baryonic Acoustic Oscillations (BAOs) traced by the Sloan Digital Sky Survey (SDSS), we put tight constraints on the main cosmological parameters. Furthermore, we study the linear matter fluctuation field of the above Liouville cosmological models. In this framework, we compare the observed growth rate of clustering measured with those predicted by the current Liouville models. Performing a chi^2 statistical test we show that the Liouville cosmological model provides growth rates that match sufficiently well with the observed growth rate. To further test the viability of the models under study, we use the Press-Schechter formalism to derive their expected redshift distribution of cluster-size halos that will be provided by future X-ray and Sunyaev-Zeldovich cluster surveys. We find that the Hubble flow differences between the Liouville and the LambdaCDM models provide a significantly different halo redshift distribution, suggesting that the models can be observationally distinguished.Comment: 15 pages, 4 figures, 4 tables, matches version to appear in Astroparticle Physic

Identification, Replication, and Fine-Mapping of Loci Associated with Adult Height in Individuals of African Ancestry

Adult height is a classic polygenic trait of high heritability (h2 ∼0.8). More than 180 single nucleotide polymorphisms (SNPs), identified mostly in populations of European descent, are associated with height. These variants convey modest effects and explain ∼10% of the variance in height. Discovery efforts in other populations, while limited, have revealed loci for height not previously implicated in individuals of European ancestry. Here, we performed a meta-analysis of genome-wide association (GWA) results for adult height in 20,427 individuals of African ancestry with replication in up to 16,436 African Americans. We found two novel height loci (Xp22-rs12393627, P = 3.4×10−12 and 2p14-rs4315565, P = 1.2×10−8). As a group, height associations discovered in European-ancestry samples replicate in individuals of African ancestry (P = 1.7×10−4 for overall replication). Fine-mapping of the European height loci in African-ancestry individuals showed an enrichment of SNPs that are associated with expression of nearby genes when compared to the index European height SNPs (P<0.01). Our results highlight the utility of genetic studies in non-European populations to understand the etiology of complex human diseases and traits

A Meta-analysis of Multiple Myeloma Risk Regions in African and European Ancestry Populations Identifies Putatively Functional Loci

Genome-wide association studies (GWAS) in European populations have identified genetic risk variants associated with multiple myeloma (MM)