Juicio cambiario

El juicio cambiario, es uno de los procesos especiales existentes, junto con el proceso monitorio, que han sido creados por el legislador en materia del derecho procesal civil, con el objetivo de poder obtener una tutela jurisdiccional frente a los derechos de crédito. Todos estos derechos de crédito, se incorporan en varios de los documentos cambiarios que existen: letras de cambio, cheques, pagarés y son regulados en la Ley de Enjuiciamiento Civil de 7 de enero del 2000, así como por la Ley Cambiaria y del Cheque de 16 de julio de 1985. Son muy importantes, porque son títulos y documentos, que a día de hoy se necesitan para poder llevar a cabo transacciones y relaciones dentro del ámbito comercial, amparando sobre todo al acreedor cambiario, otorgándole una situación procesal privilegiada, con varios trámites a su alcance, como son: la admisión de la demanda sucinta, emisión de un requerimiento judicial de pago, orden inmediata de embargo de los bienes del deudor y si éste, se opone en tiempo y forma a ese requerimiento, el poder de emitir un auto por el que se despacha en su contra una ejecución. Así, de este modo, con este tipo de proceso civil y de materia cambiaria, que se encuadra dentro de los denominados procesos especiales, se consigue poder hacer efectivos los derechos de crédito del acreedor, que puedan constar en uno de los tres títulos cambiarios existentes.The exchange trial is one of the existing special processes, together with the payment order process, which have been created by the legislator in the field of civil procedural law, with the aim of obtaining a jurisdictional protection against credit rights. All these credit rights are incorporated in several of the existing exchange documents: bills of exchange, checks and promissory notes and are regulated thanks to the new Civil Procedure Law, as well as by the Exchange and Check Law. They are very important, because they are titles and documents, which nowadays are needed on a daily basis to be able to carry out transactions and relations within the commercial sphere, protecting above all the exchange creditor, granting him a privileged procedural situation, with several procedures within his reach, such as: the admission of the brief claim, the issuance of an injunction for payment, an immediate order of seizure of the debtor's assets and if the debtor opposes in due time and form to such injunction, the power to issue a writ of execution against the debtor. This, in this way, with these various procedures, this type of civil process and of exchange matter, they manage to make effective the credit rights of the creditor, which may be stated in one of the three existing exchange instruments.Departamento de Derecho Constitucional, Procesal y Eclesiástico del EstadoGrado en Derech

Facciones, linajes y conflictos urbanos en la Europa bajomedieval. Modelos y análisis a partir de Castilla y Toscana

Urban conflicts are a main historiographical field which study has been often conditioned by prejudices and misconceptions that prevented an appropriate knowledge of the development and consequences of their social, political, anthropological and cultural manifestations. In Italian cities, the so-called weigh of the political values from the Ancient world that would have been transferred to the Western civilization, has burdened our perception of the historical reality. Particularly regarding conflicts: an aspect that did not fit the ideal political virtues of the Italian comune. In the Castilian case, the main problem is the excessive political prominence attributed to royal power and its institutional and legal system, an approach that was reinforced in the 80’s when it was linked to the origins of the «Modern State». These perspectives have limited the study of urban conflicts in a complex political society that also managed the control of violence. The article proves that, by putting aside some of the mentioned perspectives, it is possible to achieve new findings regarding conflicts, social behavior in urban history

Programa neuropsicológico para estimular las funciones cognitivas en adultos mayores víctimas de violencia psicológica, Chiclayo 2022

La presente investigación tuvo como finalidad determinar en qué medida el programa neuropsicológico estimula las funciones cognitivas en adultos mayores víctimas de violencia psicológica, Chiclayo 2022. La investigación tuvo un carácter cuantitativo, con un diseño pre experimental. Estuvo dirigida a la población adulta mayor víctimas de violencia psicológica. La muestra de estudio estuvo conformada por 25 adultos mayores del CAM Chiclayo. Las técnicas que se utilizaron fueron la entrevista, la encuesta y los instrumentos aplicados fueron la Escala de maltrato psicológico en el adulto mayor (EMAPSI) y el otro instrumento fue la adaptación peruana del Minimental State Examination (MMSE). A través del presente estudio se logró el diseño de un programa titulado “Estimulación Neuropsicológica en adultos mayores”, la cual consta de 20 sesiones. Luego se validaron las sesiones del programa a través del criterio de tres jueces expertos, donde se obtuvo un V de Aiken general de .99, reflejando que el programa es aplicable. Luego de la aplicación del programa, teniendo en cuenta los resultados de pre y post test se llegó a las siguientes conclusiones, la aplicación del programa logró una mejora significativa en las personas adultas mayores víctimas de violencia psicológica

Redefining the Common Causes of Social Struggles: An Examination of the Antinomies of Value, Labor and Subsumption

In the global contemporary political context, diverse social struggles are being alienated from each other to the point that the illusion of capitalism as the only possible socio-economic system is blurring all horizons of social change. In this article, we will aim to redefine the common causes of social struggles, by demonstrating their intersectionality and interdependence. In order to do so, we will engage with a number of concepts from Marx’s philosophy. In the introduction, we will examine the notion of value, claiming that Marx’s value theory is not simply a labor theory of value, but that it rather reflects the parallax structure of production and circulation, crystallized in the ultimate value-form of money. Having obtained these preliminary insights, we will go back to the phenomenon of labor in capitalism, to reinterpret, in the first section of the article, the Marxian distinction between productive and unproductive labor. From this will follow the first concrete examples of the intersectionality of social struggles against the abstraction of capital: namely, showing that gender and racial struggles have certain common causes, rooted in the Gramscian hegemony. In the second section, we will examine the distinction that Marx establishes between the formal and the real subsumption. The latter, we will claim, is decisive for understanding how capital structures the quasi-totality of our social relations. Following an interpretation of Maren Ade’s film Toni Erdmann, we will propose some possible means of intersectional struggle against real subsumption, that will find their theoretical backing in the concept of subversive universals. The concluding remarks will address the nuclear logic of the distribution and accumulation of capital, a symptom that survives throughout history preserved and driven by the omnipresence of ideology, and stress again implicitly the importance of common struggle in the unfreezing of emergence of a new revolutionary subject

The Cinematic Daydream as a Tool of Political Emancipation: Plus-de-Jouir, Aufhebung and the Parallax

In this research, we will start by expo- sing the paradox of ‘surplus enjoyment’ (the Lacanian plus-de-jouir), showing that its parallax structure of lack and excess is also applicable to the pheno- menon of (surplus) repression. Linking his concept with the Hegelian Aufhebung, understood as a ‘failed negation of negation’ or a ‘negation of negation’ as failure, we will focus in detail on the central example illustrating our theoretical positions, which is Iciar Bollain’s film Tambien la Lluvia (Even the Rain). In analyzing its narrative structures that address the neocolonial reality, we will tend to approach indirectly, by reading the medium of cinematic narration, the ‘neocolonial question.

Ascenso de los discursos de extrema derecha en Chile: una aproximación desde la teoría crítica

Considering the political and social contingency at the international level nowadays, but with respect to the Chilean reality, we have proposed to interpret the rise of extreme right-wing and neo-fascist discourses. To address this problem, some guidelines of psychoanalytic thought applied to the field of culture were used, which from an early date addressed the problem of interpreting sociocultural phenomena, recognizing a relationship of imbrication and continuity between the conditions of culture, the social functioning, and the ways in which these phenomena find a place of embodiment in the experience of the subject. Within this framework of interpretation, we have opted for the validity of the concepts elaborated by authors linked to critical theory, with special emphasis on the ideas established by Reich, Adorno, and Benjamin, based on their receptions of Freudian theory.Tomando en consideración la contingencia político-social actual, a nivel internacional, pero en particular respecto de la realidad chilena, nos hemos propuesto interpretar el ascenso de los discursos de extrema derecha y neofascistas. Para abordar tal problemática se recurrió a algunos lineamientos del pensamiento psicoanalítico aplicado al campo de la cultura, el cual abordó desde temprana data el problema de la interpretación de fenómenos socioculturales, dando cuenta de una relación de imbricación y continuidad entre las condiciones de la cultura, el funcionamiento social y los modos en que estos fenómenos encuentran un lugar de encarnación en la experiencia del sujeto. Dentro de este marco de interpretación hemos apostado por la vigencia de los conceptos elaborados por autores vinculados a la teoría crítica, con especial énfasis en las ideas que Reich, Adorno y Benjamin establecieron a partir de sus particulares recepciones de la teoría freudiana

The transcription factor LEF1 interacts with NFIX and switches isoforms during adult hippocampal neural stem cell quiescence

Stem cells in adult mammalian tissues are held in a reversible resting state, known as quiescence, for prolonged periods of time. Recent studies have greatly increased our understanding of the epigenetic and transcriptional landscapes that underlie stem cell quiescence. However, the transcription factor code that actively maintains the quiescence program remains poorly defined. Similarly, alternative splicing events affecting transcription factors in stem cell quiescence have been overlooked. Here we show that the transcription factor T-cell factor/lymphoid enhancer factor LEF1, a central player in canonical beta-catenin-dependent Wnt signalling, undergoes alternative splicing and switches isoforms in quiescent neural stem cells. We found that active beta-catenin and its partner LEF1 accumulated in quiescent hippocampal neural stem and progenitor cell (Q-NSPC) cultures. Accordingly, Q-NSPCs showed enhanced TCF/LEF1-driven transcription and a basal Wnt activity that conferred a functional advantage to the cultured cells in a Wnt-dependent assay. At a mechanistic level, we found a fine regulation of Lef1 gene expression. The coordinate upregulation of Lef1 transcription and retention of alternative spliced exon 6 (E6) led to the accumulation of a full-length protein isoform (LEF1-FL) that displayed increased stability in the quiescent state. Prospectively isolated GLAST + cells from the postnatal hippocampus also underwent E6 retention at the time quiescence is established in vivo. Interestingly, LEF1 motif was enriched in quiescence-associated enhancers of genes upregulated in Q-NSPCs and quiescence-related NFIX transcription factor motifs flanked the LEF1 binding sites. We further show that LEF1 interacts with NFIX and identify putative LEF1/NFIX targets. Together, our results uncover an unexpected role for LEF1 in gene regulation in quiescent NSPCs, and highlight alternative splicing as a post-transcriptional regulatory mechanism in the transition from stem cell activation to quiescence.Peer reviewe

App Kumpa-compañeros de viaje

Kumpa es una aplicativo que facilita encontrar compañeros de viaje, dirigido a turistas nacionales jóvenes, que tienen dificultades para viajar con amigos o parejas y optan por viajar solos, tienen entre 18 y 45 años de edad, pertenecen al segmento B y C y residen en Lima Metropolitana. En el capítulo 2, el lector podrá saber en qué consisten los 3 servicios que ofrece esta app. Además, podrá conocer el perfil de los integrantes del equipo de trabajo. En el capítulo 3, se detallan las oportunidades encontradas en el mercado, donde si bien el cliente viaja solitariamente, prefiere viajar acompañados. Asimismo, se señala la estrategia genérica a aplicar, así como los objetivos estratégicos. En el capítulo 4, se expone como se diseñó la propuesta de valor utilizando el método Customer Development, Lean startup y Diseño de la propuesta de valor. En el capítulo 5 se explican las estrategias de marketing a utilizar, el perfil del cliente, el tamaño de la demanda y el porcentaje de mercado a lograr durante el primero año. En el capítulo 6, se podrá encontrar la localización de la oficina administrativa, las especificaciones técnicas de la app, el detalle de la inversión total. En el capítulo 7, se encontrarán las políticas de gestión, características de la empresa y presupuesto de recursos humanos. El capítulo 8 hace énfasis en la cuantificación de las acciones y estrategias, como éstas se traducen en una TIR económica de 70.09% y un Van Económico de S/ 146,434.86 soles.Kumpa is an application that makes it easy to find travel companions, aimed at young national tourists, who have difficulties traveling with friends or couples and choose to travel alone, are between 18 and 45 years of age, belong to segment B and C and reside in Metropolitan Lima. In chapter 2, the reader will be able to know what the 3 services offered by this app consist of. In addition, you will be able to know the profile of the members of the work team. In chapter 3, the opportunities found in the market are detailed, where although the client travels alone, he prefers to travel accompanied. Likewise, the generic strategy to be applied is indicated, as well as the strategic objectives. Chapter 4 shows how the value proposition was designed using the Customer Development method, Lean startup and Design of the value proposition. Chapter 5 explains the marketing strategies to be used, the customer profile, the size of the demand and the percentage of the market to be achieved during the first year. In chapter 6, you can find the location of the administrative office, the technical specifications of the app, the detail of the total investment. In chapter 7, management policies, company characteristics and human resources budget will be found. Chapter 8 emphasizes the quantification of actions and strategies, and how these translate into an economic IRR of 70.25% and an Economic Van of S/ 146,757 soles.Trabajo de investigació

Early detection of anthracycline- and trastuzumab-induced cardiotoxicity: value and optimal timing of serum biomarkers and echocardiographic parameters.

Aims To evaluate echocardiographic and biomarker changes during chemotherapy, assess their ability to early detect and predict cardiotoxicity and to define the best time for their evaluation. Methods and results Seventy-two women with breast cancer (52 ± 9.8 years) treated with anthracyclines (26 also with trastuzumab), were evaluated for 14 months (6 echocardiograms/12 laboratory tests). We analysed: high-sensitivity cardiac troponin T, NT-proBNP, global longitudinal strain (GLS), left ventricle end-systolic volume (LVESV), left ventricle end-diastolic volume (LVEDV), and left ventricular ejection fraction (LVEF). Cardiotoxicity was defined as a reduction in LVEF>10% compared with baseline with LVEF<53%. High-sensitivity troponin T levels rose gradually reaching a maximum peak at 96 ± 13 days after starting chemotherapy (P < 0.001) and 62.5% of patients presented increased values during treatment. NT-proBNP augmented after each anthracycline cycle (mean pre-cycle levels of 72 ± 68 pg/mL and post-cycle levels of 260 ± 187 pg/mL; P < 0.0001). Cardiotoxicity was detected in 9.7% of patients (mean onset at 5.2 months). In the group with cardiotoxicity, the LVESV was higher compared with those without cardiotoxicity (40 mL vs. 29.5 mL; P = 0.045) at 1 month post-anthracycline treatment and the decline in GLS was more pronounced ( 17.6% vs. 21.4%; P = 0.03). Trastuzumab did not alter serum biomarkers, but it was associated with an increase in LVESV and LVEDV (P < 0.05). While baseline LVEF was an independent predictor of later cardiotoxicity (P = 0.039), LVESV and GLS resulted to be early detectors of cardiotoxicity [odds ratio = 1.12 (1.02–1.24), odds ratio = 0.66 (0.44–0.92), P < 0.05] at 1 month post-anthracycline treatment. Neither high-sensitivity troponin T nor NT-proBNP was capable of predicting subsequent cardiotoxicity. Conclusions One month after completion of anthracycline treatment is the optimal time to detect cardiotoxicity by means of imaging parameters (LVESV and GSL) and to determine maximal troponin rise. Baseline LVEF was a predictor of later cardiotoxicity. Trastuzumab therapy does not affect troponin values hence imaging techniques are recommended to detect trastuzumab-induced cardiotoxicity.post-print3194 K