Prevention and early detection of prostate cancer

This Review was sponsored and funded by the International Society of Cancer Prevention (ISCaP), the European Association of Urology (EAU), the National Cancer Institute, USA (NCI) (grant number 1R13CA171707-01), Prostate Cancer UK, Cancer Research UK (CRUK) (grant number C569/A16477), and the Association for International Cancer Research (AICR

Influence of clinical and neurocognitive factors in psychosocial functioning after a first episode non-affective psychosis: differences between males and females

BackgroundDeficits in psychosocial functioning are present in the early stages of psychosis. Several factors, such as premorbid adjustment, neurocognitive performance, and cognitive reserve (CR), potentially influence functionality. Sex differences are observed in individuals with psychosis in multiple domains. Nonetheless, few studies have explored the predictive factors of poor functioning according to sex in first-episode psychosis (FEP). This study aimed to explore sex differences, examine changes, and identify predictors of functioning according to sex after onset.Materials and methodsThe initial sample comprised 588 individuals. However, only adults with non-affective FEP (n = 247, 161 males and 86 females) and healthy controls (n = 224, 142 males and 82 females) were included. A comprehensive assessment including functional, neuropsychological, and clinical scales was performed at baseline and at 2-year follow-up. A linear regression model was used to determine the predictors of functioning at 2-year follow-up.ResultsFEP improved their functionality at follow-up (67.4% of both males and females). In males, longer duration of untreated psychosis (β = 0.328, p = 0.003) and worse premorbid adjustment (β = 0.256, p = 0.023) were associated with impaired functioning at 2-year follow-up, while in females processing speed (β = 0.403, p = 0.003), executive function (β = 0.299, p = 0.020) and CR (β = −0.307, p = 0.012) were significantly associated with functioning.ConclusionOur data indicate that predictors of functioning at 2-year follow-up in the FEP group differ according to sex. Therefore, treatment and preventative efforts may be adjusted taking sex into account. Males may benefit from functional remediation at early stages. Conversely, in females, early interventions centered on CR enhancement and cognitive rehabilitation may be recommended

Trattato Della Pittura Di Lionardo Da Vinci: Memorie storiche su la vita, gli studj, e le opere di Lionardo da Vinci

book; engravin

Nuova scelta d'opuscoli interessanti sulle scienze e sulle arti : tratti dagli atti delle Accademie, e dalle altre collezioni filosofiche e letterarie, dalle opere più recenti inglesi, tedesche, francesi, latine, e italiane, e dà manoscritti originali e inediti

da Carlo AmorettiForts. v.: Opuscoli scelti sulle scienze e sulle art

Viaggio da Milano ai tre laghi Maggiore, di Lugano e di Como e ne' monti che li circondano

di Carlo Amorett

Viaggio da Milano ai tre laghi Maggiore, di Lugano e di Como

[Carlo Amoretti]Verfasser gemäss 2. Aufl. v. 1801: Carlo Amorett

Kiri Michele Vincenzo Giacinto Malacarnele

Amoretti, Carlo, 1741-1816, itaalia õpetlane, Biblioteca Ambrosiana raamatukoguhoidjaMalacarne, Michele Vincenzo Giacinto, 1744-1816, itaalia meedik, anatoomia- ja kirurgiaprofesso

Primer viaje alrrededor del mundo

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