132 research outputs found
Antimicrobial Edible Films and Coatings for Meat and Meat Products Preservation
Animal origin foods are widely distributed and consumed around the world due to their high nutrients availability but may also provide a suitable environment for growth of pathogenic and spoilage microorganisms. Nowadays consumers demand high quality food with an extended shelf life without chemical additives. Edible films and coatings (EFC) added with natural antimicrobials are a promising preservation technology for raw and processed meats because they provide good barrier against spoilage and pathogenic microorganisms. This review gathers updated research reported over the last ten years related to antimicrobial EFC applied to meat and meat products. In addition, the films gas barrier properties contribute to extended shelf life because physicochemical changes, such as color, texture, and moisture, may be significantly minimized. The effectiveness showed by different types of antimicrobial EFC depends on meat source, polymer used, film barrier properties, target microorganism, antimicrobial substance properties, and storage conditions. The perspective of this technology includes tailoring of coating procedures to meet industry requirements and shelf life increase of meat and meat products to ensure quality and safety without changes in sensory characteristics
Confirmation of the Double Charm Baryon Xi_cc+ via its Decay to p D+ K-
We observes a signal for the double charm baryon Xi_cc+ in the charged decay
mode Xi_cc+ -> p D+ K- to complement the previously reported decay Xi_cc+ ->
Lambda_c K- pi+ in data from SELEX, the charm hadro-production experiment
(E781) at Fermilab. In this new decay mode we observe an excess of 5.62 events
over an expected background estimated by event mixing to be 1.38+/-0.13 events.
The Poisson probability that a background fluctuation can produce the apparent
signal is less than 6.4E-4. The observed mass of this state is
(3518+/-3)MeV/c^2, consistent with the published result. Averaging the two
results gives a mass of (3518.7+/-1.7)MeV/c^2. The observation of this new weak
decay mode confirms the previous SELEX suggestion that this state is a double
charm baryon. The relative branching ratio Gamma(Xi_cc+ -> pD+K-)/Gamma(Xi_cc+
-> Lambda_c K- pi+) = 0.36+/-0.21.Comment: 11 pages, 6 included eps figures. v2 includes improved statistical
method to determine significance of observation. Submitted to PL
First observation of a narrow charm-strange meson DsJ(2632) -> Ds eta and D0 K+
We report the first observation of a charm-strange meson DsJ(2632) at a mass
of 2632.6+/-1.6 MeV/c^2 in data from SELEX, the charm hadro-production
experiment E781 at Fermilab. This state is seen in two decay modes, Ds eta and
D0 K+. In the Ds eta decay mode we observe an excess of 49.3 events with a
significance of 7.2sigma at a mass of 2635.9+/-2.9 MeV/c^2. There is a
corresponding peak of 14 events with a significance of 5.3sigma at 2631.5+/-1.9
MeV/c^2 in the decay mode D0 K+. The decay width of this state is <17 MeV/c^2
at 90% confidence level. The relative branching ratio Gamma(D0K+)/Gamma(Dseta)
is 0.16+/-0.06. The mechanism which keeps this state narrow is unclear. Its
decay pattern is also unusual, being dominated by the Ds eta decay mode.Comment: 5 pages, 3 included eps figures. v2 as accepted for publication by
PR
An Enriched European Eel Transcriptome Sheds Light upon Host-Pathogen Interactions with Vibrio vulnificus
Infectious diseases are one of the principal bottlenecks for the European eel recovery. The aim of this study was to develop a new molecular tool to be used in host-pathogen interaction experiments in the eel. To this end, we first stimulated adult eels with different pathogen-associated molecular patterns (PAMPs), extracted RNA from the immune-related tissues and sequenced the transcriptome. We obtained more than 2 x 10(6) reads that were assembled and annotated into 45,067 new descriptions with a notable representation of novel transcripts related with pathogen recognition, signal transduction and the immune response. Then, we designed a DNA-microarray that was used to analyze the early immune response against Vibrio vulnificus, a septicemic pathogen that uses the gills as the portal of entry into the blood, as well as the role of the main toxin of this species (RtxA13) on this early interaction. The gill transcriptomic profiles obtained after bath infecting eels with the wild type strain or with a mutant deficient in rtxA13 were analyzed and compared. Results demonstrate that eels react rapidly and locally against the pathogen and that this immune-response is rtxA13-dependent as transcripts related with cell destruction were highly up-regulated only in the gills from eels infected with the wild-type strain. Furthermore, significant differences in the immune response against the wild type and the mutant strain also suggest that host survival after V. vulnificus infection could depend on an efficient local phagocytic activity. Finally, we also found evidence of the presence of an interbranchial lymphoid tissue in European eel gills although further experiments will be necessary to identify such tissue
Hippocampal CA3 Transcriptome Signature Correlates with Initial Precipitating Injury in Refractory Mesial Temporal Lobe Epilepsy
Background: Prolonged febrile seizures constitute an initial precipitating injury (IPI) commonly associated with refractory mesial temporal lobe epilepsy (RMTLE). in order to investigate IPI influence on the transcriptional phenotype underlying RMTLE we comparatively analyzed the transcriptomic signatures of CA3 explants surgically obtained from RMTLE patients with (FS) or without (NFS) febrile seizure history. Texture analyses on MRI images of dentate gyrus were conducted in a subset of surgically removed sclerotic hippocampi for identifying IPI-associated histo-radiological alterations.Methodology/Principal Findings: DNA microarray analysis revealed that CA3 global gene expression differed significantly between FS and NFS subgroups. An integrative functional genomics methodology was used for characterizing the relations between GO biological processes themes and constructing transcriptional interaction networks defining the FS and NFS transcriptomic signatures and its major gene-gene links (hubs). Co-expression network analysis showed that: i) CA3 transcriptomic profiles differ according to the IPI; ii) FS distinctive hubs are mostly linked to glutamatergic signalization while NFS hubs predominantly involve GABAergic pathways and neurotransmission modulation. Both networks have relevant hubs related to nervous system development, what is consistent with cell genesis activity in the hippocampus of RMTLE patients. Moreover, two candidate genes for therapeutic targeting came out from this analysis: SSTR1, a relevant common hub in febrile and afebrile transcriptomes, and CHRM3, due to its putative role in epilepsy susceptibility development. MRI texture analysis allowed an overall accuracy of 90% for pixels correctly classified as belonging to FS or NFS groups. Histological examination revealed that granule cell loss was significantly higher in FS hippocampi.Conclusions/Significance: CA3 transcriptional signatures and dentate gyrus morphology fairly correlate with IPI in RMTLE, indicating that FS-RMTLE represents a distinct phenotype. These findings may shed light on the molecular mechanisms underlying refractory epilepsy phenotypes and contribute to the discovery of novel specific drug targets for therapeutic interventions
The transverse momentum dependence of charged kaon Bose-Einstein correlations in the SELEX experiment
CNPQ - CONSELHO NACIONAL DE DESENVOLVIMENTO CIENTÍFICO E TECNOLÓGICOFAPESP - FUNDAÇÃO DE AMPARO À PESQUISA DO ESTADO DE SÃO PAULOWe report the measurement of the one-dimensional charged kaon correlation functions using 600GeV/c σ-, π- and 540GeV/c p beams from the SELEX (E781) experiment at the Fermilab Tevatron. K±K± correlation functions are studied for three transverse pair momentum, kT, ranges and parameterized by a Gaussian form. The emission source radii, R, and the correlation strength, λ, are extracted. The analysis shows a decrease of the source radii with increasing kaon transverse pair momentum for all beam types. © 2015 The Authors.We report the measurement of the one-dimensional charged kaon correlation functions using 600GeV/c σ-, π- and 540GeV/c p beams from the SELEX (E781) experiment at the Fermilab Tevatron. K±K± correlation functions are studied for three transverse pair momentum, kT, ranges and parameterized by a Gaussian form. The emission source radii, R, and the correlation strength, λ, are extracted. The analysis shows a decrease of the source radii with increasing kaon transverse pair momentum for all beam types.753458464CNPQ - CONSELHO NACIONAL DE DESENVOLVIMENTO CIENTÍFICO E TECNOLÓGICOFAPESP - FUNDAÇÃO DE AMPARO À PESQUISA DO ESTADO DE SÃO PAULOCNPQ - CONSELHO NACIONAL DE DESENVOLVIMENTO CIENTÍFICO E TECNOLÓGICOFAPESP - FUNDAÇÃO DE AMPARO À PESQUISA DO ESTADO DE SÃO PAULOSem informaçãoSem informaçãoRuss, J.S., Akchurin, N., Andreev, V.A., First charm hadroproduction results from SELEX (1998) ICHEP'98 Proc. Int. Conf. on High Energy Physics II, p. 1259. , arxiv:hep-ex/9812031Goldhaber, G., Fowler, W.B., Goldhaber, S., Hoang, T.F., Kalogeropoulos, T.E., Powell, W.M., Pion-pion correlations in antiproton annihilation events (1959) Phys. Rev. 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D, 48, pp. 1931-1942Csorgo, T., Kittel, W., Metzger, W.J., Novák, T., Parametrization of Bose-Einstein correlations and reconstruction of the space-time evolution of pion production in e+e- annihilation (2008) Phys. Lett. B, 663, pp. 214-216. , arxiv:0803.3528Bialas, A., Kucharczyk, M., Palka, H., Zalewski, K., Mass dependence of HBT correlations in e+e- annihilation (2000) Phys. Rev. D, 62. , arxiv:hep-ph/0006290Alexander, G., Open questions related to Bose-Einstein correlations in e+e- → hadrons (2004) Acta Phys. Pol. B, 35, pp. 69-76. , arxiv:hep-ph/0311114Alexander, G., Mass and transverse mass effects on the hadron emitter size (2001) Phys. Lett. B, 506, pp. 45-51. , arxiv:hep-ph/0101319The authors are indebted to the staff of Fermi National Accelerator Laboratory and for invaluable technical support from the staffs of collaborating institutions. This project was supported in part by Bundesministerium für Bildung, Wissenschaft, Forschung und Technologie, Consejo Nacional de Ciencia y Tecnología (CONACyT), Conselho Nacional de Desenvolvimento Científico e Tecnológico, Fondo de Apoyo a la Investigación (UASLP), Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP), the Israel Science Foundation founded by the Israel Academy of Sciences and Humanities, Istituto Nazionale di Fisica Nucleare (INFN), the International Science Foundation (ISF), the National Science Foundation, NATO, the Russian Academy of Sciences, the Russian Ministry of Science and Technology, the Russian Foundation for Basic Research (research project No. 11-02-01302-a), the Secretaría de Educación Pública (Mexico), the Turkish Scientific and Technological Research Board (TÜBİTAK), and the U.S. Department of Energy. We thank ITEP and National Research Nuclear University MEPhI (Moscow Engineering Physics Institute) for providing computing powers and support for data analysis and simulations. The authors also would like to thank Prof. Michael Lisa and Prof. Richard Lednický for helpful comments and fruitful discussions
First Observation of the Cabibbo-suppressed Decays Xi_c+ -> Sigma+ pi- pi+ and Xi_c+ -> Sigma- pi+ pi+ and Measurement of their Branching Ratios
We report the first observation of two Cabibbo-suppressed decay modes, Xi_c+
-> Sigma+ pi- pi+ and Xi_c+ -> Sigma- pi+ pi+. We observe 59+/-14 over a
background of 87, and 22+/-8 over a background of 13 events, respectively, for
the signals. The data were accumulated using the SELEX spectrometer during the
1996-1997 fixed target run at Fermilab, chiefly from a 600GeV/c Sigma- beam.
The branching ratios of the decays relative to the Cabibbo--favored Xi_c+ ->
Xi- pi+ pi+ are measured to be B(Xi_c+ -> Sigma+ pi- pi+)/B(Xi_c+ -> Xi- pi+
pi+) = 0.48+/-0.20, and B(Xi_c+ -> Sigma- pi+ pi+)/B(Xi_c+ -> Xi- pi+ pi+) =
0.18+/-0.09, respectively. We also report branching ratios for the same decay
modes of the Lambda_c+ relative to Lambda_c+ -> p K- pi+.Comment: 15 pages, 5 figures, version 2 as accepted in PL
Marine Biodiversity in the Caribbean: Regional Estimates and Distribution Patterns
This paper provides an analysis of the distribution patterns of marine biodiversity and summarizes the major activities of the Census of Marine Life program in the Caribbean region. The coastal Caribbean region is a large marine ecosystem (LME) characterized by coral reefs, mangroves, and seagrasses, but including other environments, such as sandy beaches and rocky shores. These tropical ecosystems incorporate a high diversity of associated flora and fauna, and the nations that border the Caribbean collectively encompass a major global marine biodiversity hot spot. We analyze the state of knowledge of marine biodiversity based on the geographic distribution of georeferenced species records and regional taxonomic lists. A total of 12,046 marine species are reported in this paper for the Caribbean region. These include representatives from 31 animal phyla, two plant phyla, one group of Chromista, and three groups of Protoctista. Sampling effort has been greatest in shallow, nearshore waters, where there is relatively good coverage of species records; offshore and deep environments have been less studied. Additionally, we found that the currently accepted classification of marine ecoregions of the Caribbean did not apply for the benthic distributions of five relatively well known taxonomic groups. Coastal species richness tends to concentrate along the Antillean arc (Cuba to the southernmost Antilles) and the northern coast of South America (Venezuela – Colombia), while no pattern can be observed in the deep sea with the available data. Several factors make it impossible to determine the extent to which these distribution patterns accurately reflect the true situation for marine biodiversity in general: (1) highly localized concentrations of collecting effort and a lack of collecting in many areas and ecosystems, (2) high variability among collecting methods, (3) limited taxonomic expertise for many groups, and (4) differing levels of activity in the study of different taxa
Epidemiología de la enfermedad de Chagas en el municipio Andrés Eloy Blanco, Lara, Venezuela: infestación triatomínica y seroprevalencia en humanos
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