7 research outputs found
Career paths of recipients of a master\u27s degree in health communication: understanding employment opportunities, responsibilities, and choices
A growing number of institutions offer a master\u27s degree in health communication to prepare individuals for applied work in the field, but there is very little literature on the career paths graduates pursue. The current study reports the results of a national survey that targeted the alumni of five institutions that offer the degree. Of the 522 total graduates to whom the survey was sent, 398 responded (76.2% response rate). Results show that the degree recipients have found employment in a wide variety of organizations across the country, including jobs within very prestigious organizations, such as the National Cancer Institute. Common job titles include manager, coordinator, communication associate/specialist, and program/project director. The most common job responsibilities include research activities, the development of health communication materials, project/program management, communication management, and social media/website management. The results also include stories of graduates across programs that illustrate details of career paths. The discussion of the findings addresses implications for career preparation, curriculum development, and advising
Neuron-Targeted Caveolin-1 Promotes Ultrastructural and Functional Hippocampal Synaptic Plasticity
A delicate interneuronal communication between pre- and postsynaptic membranes is critical for synaptic plasticity and the formation of memory. Evidence shows that membrane/lipid rafts (MLRs), plasma membrane microdomains enriched in cholesterol and sphingolipids, organize presynaptic proteins and postsynaptic receptors necessary for synaptic formation and signaling. MLRs establish a cell polarity that facilitates transduction of extracellular cues to the intracellular environment. Here we show that neuron-targeted overexpression of an MLR protein, caveolin-1 (SynCav1), in the adult mouse hippocampus increased the number of presynaptic vesicles per bouton, total excitatory type I glutamatergic synapses, number of same-dendrite multiple-synapse boutons, increased myelination, increased long-term potentiation, and increased MLR-localized N-methyl-d-aspartate receptor subunits (GluN1, GluN2A, and GluN2B). Immunogold electron microscopy revealed that Cav-1 localizes to both the pre- and postsynaptic membrane regions as well as in the synaptic cleft. These findings, which are consistent with a significant increase in ultrastructural and functional synaptic plasticity, provide a fundamental framework that underlies previously demonstrated improvements in learning and memory in adult and aged mice by SynCav1. Such observations suggest that Cav-1 and MLRs alter basic aspects of synapse biology that could serve as potential therapeutic targets to promote neuroplasticity and combat neurodegeneration in a number of neurological disorders