Hepatoprotective effect and GC-MS analysis of traditionally used Boswellia sacra oleo gum resin (Frankincense) extract in

Background: The water extract of oleo-gum-resin of Boswellia sacra Fleuckiger (Burseraceae) is used in the treatment of liver problems in the Middle East and Arab-African countries. The present study was carried out to evaluate its effect on liver injury induced by carbon tetrachloride in acute and chronic liver injury models.Materials and Methods: The Boswellia sacra extract was administered at doses of 2 ml/kg and 5 ml/kg. Silymarin, a known hepato-protective agent was used as standard. The extract was subjected to GC-MS analysis to determine the presence of various phyto-constituents.Results: The Boswellia sacra extract at tested doses of 2 ml/kg and 5 ml/kg significantly reduced the elevated serum levels of biomarkers in liver damage. The hepatoprotective effect was supported by changes in histopathology. The GC-MS analysis of the extract revealed the presence of several phyto-constituents that included menthol, 3-cyclohexen-1-ol and octanoic acid.Conclusion: The water extract oleo-gum-resin of Boswellia sacra possesses hepatoprotective activity, as claimed by traditional healers within the Middle East and Arab-African countries.Key words: Boswellia sacra, hepatoprotective, carbon tetrachloride, frankincense, liver damage

Cost/Benefit Evaluation Of Sulaibiya Wastewater Treatment Plant In Kuwait

In May 2001, the Government of Kuwait awarded a build, operate and transfer (BOT) contract to a local company to finance, design, build and operate an advanced wastewater treatment plant (WWTP) at Sulaibiya. The contract has a 30-year life, comprising 30 months of design and build and 27.5 years of operation and management. The total project cost was K.D. 116 million (US 442 million). The Sulaibiya plant currently treats up to 375 million imperial gallons.  It is designed for extension to 600 million imperial gallons and is the first of its kind to be built in the Middle East.  It is the largest in the world to use ultrafiltration (UF) and reverse osmosis (RO) for water purification. Ultrafiltration will remove all suspended solids and will provide a substantial reduction in micro biological activities. The main obstacle against the use of ultrafiltration membranes for WWTP has always been the higher operating cost of ultrafiltration. Up until now, this higher cost has prevented implementation of UF in all plants. A new membrane has been designed with the aim of tailoring it toward lowest total cost of ownership. Typical operating conditions have been used to quantify the following parameters for a potential large scale wastewater treatment system (UF + RO): amortization of investment in UF membranes and equipment; operating costs of the UF system; reduction in operating costs of the RO, when being compared against a conventional treatment system; and the increased output of the RO plant due to higher availability and shorter construction time. The total cost of ownership of a UF based RO plant has been determined (expressed in US/m3 of water produced). Taking all factors into account, the total cost of ownership of a dual membrane WWTP (UF + RO) will be 2–7% lower than the total cost of ownership of on conventional retreatment plant

Public Perceptions On Water Reuse Options: The Case Of Sulaibiya Wastewater Treatment Plant In Kuwait

The main sources of water in Kuwait are seawater desalination and groundwater. Reclaimed wastewater effluent could be an additional water source. Its use would reduce the volumes of recycled water being disposed of to the environment and it could reduce the demand for fresh water supplies. The results of a questionnaire survey of more than 1,500 random households residing in 64 districts in Metropolitan Kuwait are presented. The frequency distribution of the education level, knowledge of wastewater reuse, age, nationality and gender of the sample population are presented. In addition, we have presented the results of a survey of attitudes amongst residents of their willingness to use reclaimed water for a variety of purposes. The research analyzes the costs and benefits of using reclaimed water. The study concludes with useful recommendations for both the authorities and the citizens of Kuwait

Water And Other Drinks Consumption Evaluation In Kuwait

The problem of securing and gaining reliable water supplies has been an issue of great importance to the people of Kuwait, ever since the earliest days of settlement in the region. The main objective of this paper is to analyze the Kuwaitis' attitudes concerning water and other drinks consumption. A simple, yet structured questionnaire, which provides the data base for the study was designed, presented, and employed in a person-survey of a random sample of 2,500 individuals residing in the six governorates of Kuwait. The frequency distribution of the type of water (tap, filter and/or bottled), number of classes of water, number of classes of other drinks, and other socio-economic characteristics of the sample population are presented. Results show that although an overwhelming majority of Kuwaitis know that drinking water is health enhancing, most do not drink as much per day as they should. Results also show that people in Kuwait consume a lot of dehydrating drinks. More importantly, this research establishes a baseline of information about public opinion, knowledge, and behavior regarding drinking water and other drinks, so that the impact of public education programs, in particular, may be assessed and measured in the future

A DISCRETE EVENT SIMULATION (DES) BASED APPROACH TO MAXIMIZE THE PATIENT THROUGHPUT IN OUTPATIENT CLINIC

The healthcare system is a complex system which exhibits conditions of uncertainty, ambiguity emergence that incurs incoming patient congestion. Discrete event simulation (FlexSim) is considered as a viable decision support tool in analyzing a system for improvement. Using a data-driven discrete event simulation approach, this paper portrays a comprehensive analysis to maximize the number of patients in an on-campus clinic, located at Mississippi State University. The outcome of the analysis of current system exhibits that deploying a few nurse practitioners results in bottlenecks which decreases the systems’ throughput substantially due to the overall longer patients’ waiting time.  Access to the laboratory is characterized through multi-server queuing network, arrival process is followed discrete distributions, and batch sizes and arrival times are stochastic in nature. In an effort to plummet inpatient congestion at the outpatient clinic, by using empirically calibrated simulation model, we will figure out the best balance between the number of the lab technician and incoming patient during working hour. An analysis of optimal solutions is demonstrated, which is followed by recommendation and avenues for future research

HEPATOPROTECTIVE EFFECT AND GC-MS ANALYSIS OF TRADITIONALLY USED BOSWELLIA SACRA OLEO GUM RESIN (FRANKINCENSE) EXTRACT IN RATS

Background: The water extract of oleo-gum-resin of Boswellia sacra Fleuckiger (Burseraceae) is used in the treatment of liver problems in the Middle East and Arab-African countries. The present study was carried out to evaluate its effect on liver injury induced by carbon tetrachloride in acute and chronic liver injury models. Materials and Methods: The Boswellia sacra extract was administered at doses of 2 ml/kg and 5 ml/kg. Silymarin, a known hepato-protective agent was used as standard. The extract was subjected to GC-MS analysis to determine the presence of various phyto-constituents. Results: The Boswellia sacra extract at tested doses of 2 ml/kg and 5 ml/kg significantly reduced the elevated serum levels of biomarkers in liver damage. The hepatoprotective effect was supported by changes in histopathology. The GC-MS analysis of the extract revealed the presence of several phyto-constituents that included menthol, 3-cyclohexen-1-ol and octanoic acid. Conclusion: The water extract oleo-gum-resin of Boswellia sacra possesses hepatoprotective activity, as claimed by traditional healers within the Middle East and Arab-African countries

Assessment of health-care waste management in a humanitarian crisis: a case study of the Gaza Strip

Health-care waste management requires technical, financial and human resources, and it is a challenge for low- and middle income countries, while it is often neglected in protracted crisis or emergency situations. Indeed, when health, safety, security or wellbeing of a community is threatened, solid waste management usually receives limited attention. Using the Gaza Strip as the case study region, this manuscript reports on health-care waste management within the context of a humanitarian crisis. The study employed a range of methods including content analyses of policies and legislation, audits of waste arisings, field visits, stakeholder interviews and evaluation of treatment systems. The study estimated a production from clinics and hospitals of 683 kg/day of hazardous waste in the Gaza Strip, while the total health-care waste production was 3357 kg/day. A number of challenges was identified including lack of clear definitions and regulations, limited accurate data on which to base decisions and strategies and poor coordination amongst key stakeholders. Hazardous and non-hazardous waste was partially segregated and treatment facilities hardly used, and 75% of the hazardous waste was left untreated. Recommendations for mitigating these challenges posed to patients, staff and the community in general are suggested. The outputs are particularly useful to support decision makers, and re-organize the system according to reliable data and sound assumptions. The methodology can be replicated in other humanitarian settings, also to other waste flows, and other sectors of environmental sanitation

Optimal design of water treatment processes

Predicted water shortages assign water treatment a leading role in improving water resources management. One of the main challenges associated with the processes remains early stage design of techno-economically optimised purification. This work addresses the current gap by undertaking a whole-system approach of flowsheet synthesis for the production of water at desired purity at minimum overall cost. The optimisation problem was formulated as a mixed-integer non-linear programming model. Two case studies were presented which incorporated the most common commercial technologies and the major pollution indicators, such as chemical oxygen demand, dissolved organic carbon, total suspended solids and total dissolved solids. The results were analysed and compared to existing guidelines in order to examine the applicability of the proposed approach

Improving girls’ perception of computer science as a viable career option through game playing and design: Lessons from a systematic literature review

The objective of exposing girls to Computer Science as a career option has led to research directed towards gaming activities for girls. These activities include both game play and game design. Research about gaming activities for increasing girls’ interest in computer science has gained much attention over the past few years and has resulted in a number of contributions. We follow up with an overview of the status of research through a Systematic Literature Review. We investigate the relation between the various game playing or designing activities and their impact on girls’ perception of Computer Science as a career choice. We further present the design consideration for the games and related activities to potentially improve the perception of girls towards a Computer Science career. The applied method is a Systematic Literature Review through which we investigate which contributions were made, which knowledge areas were most explored, and which research facets have been used. We identify 25 papers to distill a common understanding of the state-of-the-art. Specifically, we investigate the effects that the game play/design activities had on girls’ perception about Computer Science; and what are the key design factors to be kept in mind while designing a serious game to improve girls’ perception about Computer Science. The results of this systematic literature review show that game playing or designing could indeed improve how girls perceive having a career in CS. The key aspects that such activities require are personalizing, opportunity for collaboration and the presence of a female lead characterThis work has been done during the tenure of an ERCIM Alain Bensoussan fellowshi