Nasalisation - overdo or necessity. A retrospective study

Surgical treatment of nasal polyposis has been successfully treated with functional endoscopic sinus surgery (FESS) or nasalisation – a more radical approach involving removal of the bony lamellae and mucosa of the ethmoid labyrinth, sphenoidotomy, frontotomy, middle turbinectomy and an antrostomy. This study observed the results of 794 surgeries performed by a single surgeon in the period from January 2012 to December 2022 and compared the success of those two methods. The study observed 594 FESS patients and 130 nasalisation patients. In the nasalisation group, 40 patients had unilateral nasalisation, while the remaining 90 had bilateral nasalisation. The patients in both groups were controlled preoperatively as well as 1, 3 and 6 months after surgery. The patients where nasalisation was performed on average had a worse starting point (more intense congestion symptoms). The surgeon discussed their subjective opinion on nasal breathing improvement before and after the treatment as well as endoscopic findings and compared it at each timepoint. The results show that the patients undergoing nasalisation procedure had better results when compared to FESS group. This study indicates that when a more radical tissue removal is performed (nasalisation), the nasal function is improved compared to the more conservative treatment method (FESS)

Nasalisation - overdo or necessity. A retrospective study

Surgical treatment of nasal polyposis has been successfully treated with functional endoscopic sinus surgery (FESS) or nasalisation – a more radical approach involving removal of the bony lamellae and mucosa of the ethmoid labyrinth, sphenoidotomy, frontotomy, middle turbinectomy and an antrostomy. This study observed the results of 794 surgeries performed by a single surgeon in the period from January 2012 to December 2022 and compared the success of those two methods. The study observed 594 FESS patients and 130 nasalisation patients. In the nasalisation group, 40 patients had unilateral nasalisation, while the remaining 90 had bilateral nasalisation. The patients in both groups were controlled preoperatively as well as 1, 3 and 6 months after surgery. The patients where nasalisation was performed on average had a worse starting point (more intense congestion symptoms). The surgeon discussed their subjective opinion on nasal breathing improvement before and after the treatment as well as endoscopic findings and compared it at each timepoint. The results show that the patients undergoing nasalisation procedure had better results when compared to FESS group. This study indicates that when a more radical tissue removal is performed (nasalisation), the nasal function is improved compared to the more conservative treatment method (FESS)

An assessment of the levels of phthalate esters and metals in the Muledane open dump, Thohoyandou, Limpopo Province, South Africa

<p>Abstract</p> <p>Background</p> <p>This work reports the determination of the levels of phthalate esters (dimethyl phthalate (DMP), diethyl phthalate (DEP), dibutyl phthalate (DBP), diethyl hexyl phthalate (DEHP)) and metals (lead, cadmium, manganese, zinc, iron, calcium) in composite soil samples. The soil samples were collected randomly within the Muledane open dump, Thohoyandou, Limpopo province, South Africa. Control samples were collected about 200 m away from the open dump. The phthalate esters were separated and determined by capillary gas chromatography with a flame ionization detector, whilst the metals were determined by atomic absorption spectrophotometry.</p> <p>Results</p> <p>Open dump values for the phthalate esters and metals to be generally higher in comparison to control samples for DMP, DEP, DBP and DEHP – the mean values calculated were 0.31 ± 0.12, 0.21 ± 0.05, 0.30 ± 0.07, and 0.03 ± 0.01 mg/kg, respectively, for the open dump soil samples. Nonetheless, the mean open dump values for lead, cadmium, manganese, zinc, iron and calcium were 0.07 ± 0.04, 0.003 ± 0.001, 5.02 ± 1.92, 0.31 ± 0.02, 11.62 ± 9.48 and 0.12 ± 0.13 mg/kg, respectively. The results were compared statistically.</p> <p>Conclusion</p> <p>Our results revealed that the discarding of wastes into the open dump is a potential source of soil contamination in the immediate vicinity and beyond, <it>via </it>dispersal. Increased levels of phthalate esters and metals in the soil pose a risk to public health, plants and animals. Sustained monitoring of these contaminants is recommended, in addition to upgrading the facility to a landfill.</p

Effects of environmental pollutants on the reproduction and welfare of ruminants

Anthropogenic pollutants comprise a wide range of synthetic organic compounds and heavy metals, which are dispersed throughout the environment, usually at low concentrations. Exposure of ruminants, as for all other animals, is unavoidable and while the levels of exposure to most chemicals are usually too low to induce any physiological effects, combinations of pollutants can act additively or synergistically to perturb multiple physiological systems at all ages but particularly in the developing foetus. In sheep, organs affected by pollutant exposure include the ovary, testis, hypothalamus and pituitary gland and bone. Reported effects of exposure include changes in organ weight and gross structure, histology and gene and protein expression but these changes are not reflected in changes in reproductive performance under the conditions tested. These results illustrate the complexity of the effects of endocrine disrupting compounds on the reproductive axis, which make it difficult to extrapolate between, or even within, species. Effects of pollutant exposure on the thyroid gland, immune, cardiovascular and obesogenic systems have not been shown explicitly, in ruminants, but work on other species suggests that these systems can also be perturbed. It is concluded that exposure to a mixture of anthropogenic pollutants has significant effects on a wide variety of physiological systems, including the reproductive system. Although this physiological insult has not yet been shown to lead to a reduction in ruminant gross performance, there are already reports indicating that anthropogenic pollutant exposure can compromise several physiological systems and may pose a significant threat to both reproductive performance and welfare in the longer term. At present, many potential mechanisms of action for individual chemicals have been identified but knowledge of factors affecting the rate of tissue exposure and of the effects of combinations of chemicals on physiological systems is poor. Nevertheless, both are vital for the identification of risks to animal productivity and welfare

Therapeutic interventions for parents with personality disorder

PO su prožimajući, nefleksibilni i stalni oblici ponašanja koji uzrokuju značajnu subjektivnu trpnju ili poremećaj u funkcioniranju. Kada pacijenti postanu roditelji, ti poremećaji utječu na njihovo roditeljstvo i mogu imati štetne učinke na njihovu djecu. Podaci dobiveni na uzorku osoba koje se liječi izvanbolnički govore da je 37% osoba s PO ostvarilo roditeljstvo. Postoji dovoljno dokaza da se PO mogu liječiti odgovarajućim tretmanom jer je pružanje pomoći i usluga od ključne važnosti ne samo za roditelje osobno, već i za njihovu djecu. Postoji nekoliko strukturiranih oblika ovakve psihoterapije usmjerene na odnos roditelj-dijete, od kojih je najvažniji Gledajte, čekajte i čudite se, te Zračni projekt. Gledajte, čekajte i čudite se intervencija uključuje 12-14 terapijskih susreta u periodu od 5 mjeseci. Terapeut poziva majku da prati dijete u igranju s igračkama, a zatim razgovara s majkom o aktivnostima koje je započelo dijete, te o djetetovom ponašanju tijekom seanse igranja. Zračni projekt druga je terapijska intervencija koja potiče sigurnost djece, podučavajući roditelje s PO da razumiju i ispunjavaju potrebe svoje djece, razvijajući krizne planove i učeći opće roditeljske vještine poput postavljanja pravila i ograničenja za djecu. U Hrvatskoj postoje službe koje se bave liječenjem osoba oboljelih od PO, ali one trenutno ne nude specifične intervencije za roditelje s PO. Motivirani roditelji koji imaju uvid u svoje potešoće i žele unaprijediti svoje roditeljstvo i odnos s djecom, te roditelji kojima su dijete ili djeca oduzeti, a odlučuju se imati još djece ciljne su skupine kojima bi imalo smisla ponuditi navedene intervencije.Personality disorders are pervasive, inflexible and ongoing behaviors that receive significant suffering or functional impairment. When patients become parents, these disorders affect their parenthood and can have adverse effects on their children. Data from an outpatient sample of adult mental health indicate that 37% of people with personality disorders have achieved parenting. There is ample evidence that personality disorders can be treated with proper therapy because it has provided assistance and service of important help for parents and their children. There are several codified examples of parent-child therapeutic interventions. The most important are: Watch, Wait and Wonder and Project Air. The Watch, Wait and Wonder intervention includes 12-14 sessions of therapy over a period of 5 months. The therapist encourages the mother to accompany the child in playing with the toys and than discusses with the mother the activity that the child started. Project Air is another therapeutic intervention that promotes child safety, thus teaching parents with personality disorders to understand and meet their children's needs, develop crisis plans and general parenting skills like setting rules and limits for children. There are services in Croatia that deal with the treatment of people with personality disorders, but currently does not offer special interventions for parents with personality disorders. The target groups of parents to provide these interventions are: motivated parents who have insight into their difficulties and want to improve their parent-child relationship and parents whose child or children are taken away, but desire to have more children

Therapeutic interventions for parents with personality disorder

PO su prožimajući, nefleksibilni i stalni oblici ponašanja koji uzrokuju značajnu subjektivnu trpnju ili poremećaj u funkcioniranju. Kada pacijenti postanu roditelji, ti poremećaji utječu na njihovo roditeljstvo i mogu imati štetne učinke na njihovu djecu. Podaci dobiveni na uzorku osoba koje se liječi izvanbolnički govore da je 37% osoba s PO ostvarilo roditeljstvo. Postoji dovoljno dokaza da se PO mogu liječiti odgovarajućim tretmanom jer je pružanje pomoći i usluga od ključne važnosti ne samo za roditelje osobno, već i za njihovu djecu. Postoji nekoliko strukturiranih oblika ovakve psihoterapije usmjerene na odnos roditelj-dijete, od kojih je najvažniji Gledajte, čekajte i čudite se, te Zračni projekt. Gledajte, čekajte i čudite se intervencija uključuje 12-14 terapijskih susreta u periodu od 5 mjeseci. Terapeut poziva majku da prati dijete u igranju s igračkama, a zatim razgovara s majkom o aktivnostima koje je započelo dijete, te o djetetovom ponašanju tijekom seanse igranja. Zračni projekt druga je terapijska intervencija koja potiče sigurnost djece, podučavajući roditelje s PO da razumiju i ispunjavaju potrebe svoje djece, razvijajući krizne planove i učeći opće roditeljske vještine poput postavljanja pravila i ograničenja za djecu. U Hrvatskoj postoje službe koje se bave liječenjem osoba oboljelih od PO, ali one trenutno ne nude specifične intervencije za roditelje s PO. Motivirani roditelji koji imaju uvid u svoje potešoće i žele unaprijediti svoje roditeljstvo i odnos s djecom, te roditelji kojima su dijete ili djeca oduzeti, a odlučuju se imati još djece ciljne su skupine kojima bi imalo smisla ponuditi navedene intervencije.Personality disorders are pervasive, inflexible and ongoing behaviors that receive significant suffering or functional impairment. When patients become parents, these disorders affect their parenthood and can have adverse effects on their children. Data from an outpatient sample of adult mental health indicate that 37% of people with personality disorders have achieved parenting. There is ample evidence that personality disorders can be treated with proper therapy because it has provided assistance and service of important help for parents and their children. There are several codified examples of parent-child therapeutic interventions. The most important are: Watch, Wait and Wonder and Project Air. The Watch, Wait and Wonder intervention includes 12-14 sessions of therapy over a period of 5 months. The therapist encourages the mother to accompany the child in playing with the toys and than discusses with the mother the activity that the child started. Project Air is another therapeutic intervention that promotes child safety, thus teaching parents with personality disorders to understand and meet their children's needs, develop crisis plans and general parenting skills like setting rules and limits for children. There are services in Croatia that deal with the treatment of people with personality disorders, but currently does not offer special interventions for parents with personality disorders. The target groups of parents to provide these interventions are: motivated parents who have insight into their difficulties and want to improve their parent-child relationship and parents whose child or children are taken away, but desire to have more children

Therapeutic interventions for parents with personality disorder

PO su prožimajući, nefleksibilni i stalni oblici ponašanja koji uzrokuju značajnu subjektivnu trpnju ili poremećaj u funkcioniranju. Kada pacijenti postanu roditelji, ti poremećaji utječu na njihovo roditeljstvo i mogu imati štetne učinke na njihovu djecu. Podaci dobiveni na uzorku osoba koje se liječi izvanbolnički govore da je 37% osoba s PO ostvarilo roditeljstvo. Postoji dovoljno dokaza da se PO mogu liječiti odgovarajućim tretmanom jer je pružanje pomoći i usluga od ključne važnosti ne samo za roditelje osobno, već i za njihovu djecu. Postoji nekoliko strukturiranih oblika ovakve psihoterapije usmjerene na odnos roditelj-dijete, od kojih je najvažniji Gledajte, čekajte i čudite se, te Zračni projekt. Gledajte, čekajte i čudite se intervencija uključuje 12-14 terapijskih susreta u periodu od 5 mjeseci. Terapeut poziva majku da prati dijete u igranju s igračkama, a zatim razgovara s majkom o aktivnostima koje je započelo dijete, te o djetetovom ponašanju tijekom seanse igranja. Zračni projekt druga je terapijska intervencija koja potiče sigurnost djece, podučavajući roditelje s PO da razumiju i ispunjavaju potrebe svoje djece, razvijajući krizne planove i učeći opće roditeljske vještine poput postavljanja pravila i ograničenja za djecu. U Hrvatskoj postoje službe koje se bave liječenjem osoba oboljelih od PO, ali one trenutno ne nude specifične intervencije za roditelje s PO. Motivirani roditelji koji imaju uvid u svoje potešoće i žele unaprijediti svoje roditeljstvo i odnos s djecom, te roditelji kojima su dijete ili djeca oduzeti, a odlučuju se imati još djece ciljne su skupine kojima bi imalo smisla ponuditi navedene intervencije.Personality disorders are pervasive, inflexible and ongoing behaviors that receive significant suffering or functional impairment. When patients become parents, these disorders affect their parenthood and can have adverse effects on their children. Data from an outpatient sample of adult mental health indicate that 37% of people with personality disorders have achieved parenting. There is ample evidence that personality disorders can be treated with proper therapy because it has provided assistance and service of important help for parents and their children. There are several codified examples of parent-child therapeutic interventions. The most important are: Watch, Wait and Wonder and Project Air. The Watch, Wait and Wonder intervention includes 12-14 sessions of therapy over a period of 5 months. The therapist encourages the mother to accompany the child in playing with the toys and than discusses with the mother the activity that the child started. Project Air is another therapeutic intervention that promotes child safety, thus teaching parents with personality disorders to understand and meet their children's needs, develop crisis plans and general parenting skills like setting rules and limits for children. There are services in Croatia that deal with the treatment of people with personality disorders, but currently does not offer special interventions for parents with personality disorders. The target groups of parents to provide these interventions are: motivated parents who have insight into their difficulties and want to improve their parent-child relationship and parents whose child or children are taken away, but desire to have more children

Slagalica nasljeđa : priručnik za opismenjavanje iz medicinske genetike

"Slagalica nasljeđa" - priručnik za opismenjavanje iz medicinske genetike ima tri namjene. Prije svega, on je edukativna slikovnica za studente, liječnike i pacijente, ali i druge zainteresirane pojedince jer su u njoj kroz ilustracije objašnjene osnove genetike čovjeka, kao i osnove medicinske genetike. Od toga kako prepoznati osobu s genetičkim poremećajem, kako nastaju i koje vrste genetičkih poremećaja postoje pa sve do toga na koji ih način možemo dijagnosticirati. Nadalje, nakon svake ilustracije na pojedinoj stranici nalaze se definicije 79 pojmova iz medicinske genetike koje čine tezaurus za studente, liječnike i pacijente koji se na bilo koji način susreću s genetičkim poremećajima. Naposljetku, ova knjiga sadrži i primjere rečenica u koje su ubačeni stručni pojmovi iz medicinske genetike, a koji su namijenjeni studentima prilikom savladavanja komunikacijskih vještina na kolegiju Medicinska genetika, ali i liječnicima prilikom informiranja svojih pacijenata o (mogućem) genetičkom poremećaju. Uz kreatoricu ideje i urednicu izdanja, doc. dr. sc. Ninu Perezu, autori izdanja su studenti šeste godine Integriranog preddiplomskog i diplomskog sveučilišnog studija Medicina i prof. dr. sc. Saša Ostojić

Slagalica nasljeđa : priručnik za opismenjavanje iz medicinske genetike

"Slagalica nasljeđa" - priručnik za opismenjavanje iz medicinske genetike ima tri namjene. Prije svega, on je edukativna slikovnica za studente, liječnike i pacijente, ali i druge zainteresirane pojedince jer su u njoj kroz ilustracije objašnjene osnove genetike čovjeka, kao i osnove medicinske genetike. Od toga kako prepoznati osobu s genetičkim poremećajem, kako nastaju i koje vrste genetičkih poremećaja postoje pa sve do toga na koji ih način možemo dijagnosticirati. Nadalje, nakon svake ilustracije na pojedinoj stranici nalaze se definicije 79 pojmova iz medicinske genetike koje čine tezaurus za studente, liječnike i pacijente koji se na bilo koji način susreću s genetičkim poremećajima. Naposljetku, ova knjiga sadrži i primjere rečenica u koje su ubačeni stručni pojmovi iz medicinske genetike, a koji su namijenjeni studentima prilikom savladavanja komunikacijskih vještina na kolegiju Medicinska genetika, ali i liječnicima prilikom informiranja svojih pacijenata o (mogućem) genetičkom poremećaju. Uz kreatoricu ideje i urednicu izdanja, doc. dr. sc. Ninu Perezu, autori izdanja su studenti šeste godine Integriranog preddiplomskog i diplomskog sveučilišnog studija Medicina i prof. dr. sc. Saša Ostojić