Vigilancia Epidemiológica y la atención primaria en salud Post-Pandemia del Covid-19 en la Población vulnerable del Cantón Jipijapa

Ecuador has undertaken important reforms in search of universality and equity, however, the system remains fragmented and does not guarantee universal access. Epidemiological Surveillance and post-pandemic Primary Health Care (PHC) in the most vulnerable population of the Jipijapa Canton are essential elements for health regulatory entities. The canton, guided by the Ministry of Public Health and other public and private non-governmental sectors and civil society, as a new model of integrated health care system. This research aims to describe the results obtained in the intervention of the project of linkage with society such as "Epidemiological Surveillance and Primary Health Care (APS) post-pandemic in the most vulnerable population of the Jipijapa Canton", the research was not Experimental, the descriptive, field method was used, applying an information collection instrument to 4066 homes in the urban and rural parishes of the Jipijapa canton, with the active intervention of sixth semester nursing students and teachers from the Southern State University. of Manabí, keeping ethical and methodological characteristics of rigor, with the purpose of minimizing or destroying the reservoirs of the reproduction of vector diseases in different areas of the canton.Ecuador ha emprendido importantes reformas en búsqueda de la universalidad y equidad, sin embargo, el sistema continúa fragmentado y no garantiza el acceso universal. La Vigilancia Epidemiológica y la Atención Primaria en Salud (APS) post-pandemia en la población más vulnerable del Cantón Jipijapa, son elementos esenciales para los entes reguladores de salud. El cantón, guiado por Ministerio de Salud Pública y otros sectores públicos y privados no gubernamentales y la sociedad civil, como un nuevo modelo de sistema de atención sanitario integrado. Esta investigacion tiene con objetivo describir los resultados obtenidos en la intervención del proyecto de vinculación con la sociedad como es ¨Vigilancia Epidemiológica y la Atención Primaria en Salud (APS) post-pandemia en la población más vulnerable del Cantón Jipijapa¨, La investigación fue no experimental, se utilizó el método descriptivo, de campo, aplicando un instrumento de recolección de información a 4066 viviendas de las parroquias urbanas y rurales del cantón Jipijapa, con la intervención activa de estudiantes de enfermería del sexto semestre y docentes de la Universidad Estatal del Sur de Manabí, guardando características éticas y metodológicas de rigor, con la finalidad de minimizar o destruir los reservorios de la reproducción de enfermedades vectoriales en diferentes áreas del cantón

A GIS-supported Multidisciplinary Database for the Management of UNESCO Global Geoparks: the Courel Mountains Geopark (Spain)

[Abstract] The management of a UNESCO Global Geopark (UGGp) requires a vast wealth of miscellaneous scientific knowledge that can be successfully organised using a Geographical Information System (GIS). This paper presents a pragmatic GIS database to assist in the suitable governance of the Courel Mountains UGGp (2017) in Northwest Spain. The database is structured in 66 coverages compiled from public sources and previous works or produced through traditional mapping (combining fieldwork and photointerpretation) and GIS tools. The acquired data was later homogenised and validated by a multidisciplinary team and archived in independent coverages. Forty thematic maps illustrate the broad range of cartographic information included in the GIS database. Among them, 25 basic maps provide an overview of the UGGp and 15 new maps focus on crosscutting and technical issues. All maps illustrate the huge potential of GIS to create new resources combining coverages and adapting the legend according to their purpose and audience. The database facilitates the suitable publishing of consistent outputs (e.g., brochures, books, panels, webpages, web serves), as well as the elaboration of technical data to assist the park management. The database furnishes information on the design of education actions, touristic routes, activities and Geopark facilities. The GIS database is also a supportive tool for scientific research and provides the necessary knowledge to conduct geoconservation actions based on land use, geological hazards and the occurrence of natural and cultural heritages. Altogether, the GIS database constitutes a powerful instrument for policy-making, facilitating the identification and evaluation of alternative strategy plans.This work was developed in the framework of the Scientific Program of the Courel Mountains UGGp with the cooperation of tourism agents (A.M. Arza and A. López), roofing slate quarries (Pizarras de Villarbacú, Pizarras de Quiroga) and local people (M. Reinosa, G. Díaz, O. Álvarez). We are deeply grateful to J.R. Martínez Catalán (Universidad de Salamanca), A. Pérez-Alberti and J. Guitián (both from Universidade de Santiago de Compostela), J.R. Gutiérrez-Marco (ICOG, Universidad Complutense de Madrid/CSIC), J. Vegas (IGME-CSIC), L. González-Menéndez (IGME-CSIC), J.M. García Queijeiro (Universidade de Vigo), L. Santos and A. Grandal-D’Anglade (both from Universidade da Coruña) for their assistance supplying information involved in the database. We thank also E. de Boer for proofreading the article. DB is grant holder of Plan Andaluz de Investigación, Desarrollo e Innovación 2021, funded by Junta de Andalucí

Design of a GIS-database for the management of the Courel Mountains UNESCO Global Geopark (Spain)

X Congreso Geológico de España, 5-7 Julio 2021, Vitoria - GasteizSe ha desarrollado una base de datos en un sistema de información geográfica (SIG) para la gestión del Geoparque Mundial de la UNESCO Montañas do Courel (NO de España). El SIG incluye 66 capas de información topográfica, geológica, minera, biológica, arqueológica y etnográfica, que pueden ser combinadas entre sí para elaborar mapas temáticos adaptados a la finalidad y al usuario. Los mapas generados son empleados en actividades de divulgación, en el diseño de cartografías técnicas de apoyo a los gestores del Geoparque, en el desarrollo de estudios científicos y en acciones de geoconservació

Brentuximab vedotin in the treatment of cutaneous T-cell lymphomas: Data from the Spanish Primary Cutaneous Lymphoma Registry

[Background] Brentuximab vedotin (BV) has been approved for CD30-expressing cutaneous T-cell lymphoma (CTCL) after at least one previous systemic treatment. However, real clinical practice is still limited.[Objectives] To evaluate the response and tolerance of BV in a cohort of patients with CTCL.[Methods] We analysed CTCL patients treated with BV from the Spanish Primary Cutaneous Lymphoma Registry (RELCP).[Results] Sixty-seven patients were included. There were 26 females and the mean age at diagnosis was 59 years. Forty-eight were mycosis fungoides (MF), 7 Sézary syndrome (SS) and 12 CD30+ lymphoproliferative disorders (CD30 LPD). Mean follow-up was 18 months. Thirty patients (45%) showed at least 10% of CD30+ cells among the total lymphocytic infiltrate. The median number of BV infusions received was 7. The overall response rate (ORR) was 67% (63% in MF, 71% in SS and 84% in CD30 LPD). Ten of 14 patients with folliculotropic MF (FMF) achieved complete or partial response (ORR 71%). The median time to response was 2.8 months. During follow-up, 36 cases (54%) experienced cutaneous relapse or progression. The median progression free survival (PFS) was 10.3 months. The most frequent adverse event was peripheral neuropathy (PN) (57%), in most patients (85%), grades 1 or 2.[Conclusions] These results confirm the efficacy and safety of BV in patients with advanced-stage MF, and CD30 LPD. In addition, patients with FMF and SS also showed a favourable response. Our data suggest that BV retreatment is effective in a proportion of cases.The Spanish Primary Cutaneous Lymphoma Registry (RELCP) is promoted by the Fundación Piel Sana Academia Española de Dermatología y Venereología, which received an unrestricted grant support from Kyowa Kirin.Peer reviewe

Cirugía oncológica: Nuevos enfoques en la resección de tumores

Introduction: Oncologic surgery is a recent denomination for a millenary practice. The emergence of hospitals dedicated to cancer management led to the creation of oncologic surgery departments and the separation of the general surgeon to the specialized cancer surgeon, defining the formation of this new specialty. Development: The development addresses the background and evolution of oncologic surgery, explains the various advances in pediatric tumors and current practical applications of minimally invasive surgery, as well as breast cancer, in the elderly, head and neck. Concluding with future lines of research with respect to the subject matter addressed in the article . Conclusions: Oncologic surgery has evolved substantially by applying innovative strategies that improve results and quality of life. Research continues, ethics and multidisciplinary collaboration are crucial to advance in the treatment of cancer.Introducción: La cirugía oncológica es una denominación reciente para una práctica milenaria. La aparición de hospitales dedicados al manejo del cáncer llevó a la creación de departamentos de cirugía oncológica y la separación del cirujano general hacia el cirujano especializado en cáncer, definiendo la formación de esta nueva especialidad   Desarrollo: El desarrollo aborda los antecedentes y evolución de la cirugía oncológica, se explica los diferentes avances en tumores pediátrico y las aplicaciones practica actuales de la cirugía mínimamente invasiva .Además se aborda el cáncer de mama , en el adulto mayor , cabeza y cuello. Concluyendo con las futuras líneas de investigación con respecto a la temática abordada en el artículo .   Conclusiones: La Cirugía Oncológica ha evolucionado sustancialmente aplicando estrategias innovadoras que mejoran resultados y calidad de vida. Las investigaciones continúan, la ética y la colaboración multidisciplinaria son cruciales para avanzar en el tratamiento del cáncer

Brentuximab vedotin in the treatment of cutaneous T-cell lymphomas: data from the Spanish primary cutaneous lymphoma registry

Background: Brentuximab vedotin (BV) has been approved for CD30-expressing cutaneous T-cell lymphoma (CTCL) after at least one previous systemic treatment. However, real clinical practice is still limited. Objectives: To evaluate the response and tolerance of BV in a cohort of patients with CTCL. Methods: We analysed CTCL patients treated with BV from the Spanish Primary Cutaneous Lymphoma Registry (RELCP). Results: Sixty-seven patients were included. There were 26 females and the mean age at diagnosis was 59 years. Forty-eight were mycosis fungoides (MF), 7 Sézary syndrome (SS) and 12 CD30+ lymphoproliferative disorders (CD30 LPD). Mean follow-up was 18 months. Thirty patients (45%) showed at least 10% of CD30+ cells among the total lymphocytic infiltrate. The median number of BV infusions received was 7. The overall response rate (ORR) was 67% (63% in MF, 71% in SS and 84% in CD30 LPD). Ten of 14 patients with folliculotropic MF (FMF) achieved complete or partial response (ORR 71%). The median time to response was 2.8 months. During follow-up, 36 cases (54%) experienced cutaneous relapse or progression. The median progression free survival (PFS) was 10.3 months. The most frequent adverse event was peripheral neuropathy (PN) (57%), in most patients (85%), grades 1 or 2. Conclusions: These results confirm the efficacy and safety of BV in patients with advanced-stage MF, and CD30 LPD. In addition, patients with FMF and SS also showed a favourable response. Our data suggest that BV retreatment is effective in a proportion of cases