Influence of the seabed on surface noise intensity vector in shallow water

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Evaluation of VCAM-1 and ICAM-1 concentration and values of global tests concerning the coagulation system of patients suffering from subarachnoid haemorrage

Introduction The term ‘subarachnoid haemorrhage’ (SAH) stands for bleeding into the subarachnoid space, regardless of its source. It may be of primary character when the source of bleeding is situated within the subarachnoid space. Subarachnoid haemorrhage is often described as spontaneous bleeding, mainly in order to differentiate it from post-traumatic bleeding. Objective The aim of the study was to evaluate the concentration of ICAM-1 and VCAM-1 in the blood of patients in the early phase following subarachnoid haemorrhage in terms of searching for markers useful in subarachnoid bleeding diagnostics and monitoring a patient’s clinical state. Material and Methods The study comprised 85 patients (47 women, 38 men), aged 29–81 (average 53±12 years), suffering from subarachnoid haemorrhage. The control group comprised 45 healthy people selected according to gender and age corresponding with the experimental group. Results The study revealed that the concentration of ICAM-1 and VCAM-1 was significantly higher in patients suffering from subarachnoid haemorrhage. Additionally, the concentration of fibrinogen decreased, aPTT was shorter and the concentration of D-dimers increased. The studied parameters did not differ with respect to the age or gender of the patients. It was stated that according to the Hunt and Hess scale, the concentration of ICAM-1 was considerably higher in the group of patients in the most severe neurological state, compared to other patients. It was also observed that the concentration of fibrinogen was significantly higher, aPTT was shorter, and the concentration of D-dimers increased in the afore-mentioned group. Conclusions Evaluation of the concentration of adhesion molecules, as well as values of global tests concerning the coagulation system, may serve as a useful diagnostic tool for SAH

Urban warfare ecology: A study of water supply in Basrah

This article assesses the impact of armed conflict on the drinking water service of Basrah from 1978 to 2013 through an ‘urban warfare ecology’ lens in order to draw out the implications for relief programming and relevance to urban studies. It interprets an extensive range of unpublished literature through a frame that incorporates the accumulation of direct and indirect impacts upon the hardware, consumables and people upon which urban services rely. The analysis attributes a step-wise decline in service quality to the lack of water treatment chemicals, lack of spare parts, and, primarily, an extended ‘brain-drain’ of qualified water service staff. The service is found to have been vulnerable to dependence upon foreign parts and people, ‘vicious cycles’ of impact, and the politics of aid and of reconstruction. It follows that practitioners and donors eschew ideas of relief–rehabilitation–development (RRD) for an appreciation of the needs particular to complex urban warfare biospheres, where armed conflict and sanctions permeate all aspects of service provision through altered biological and social processes. The urban warfare ecology lens is found to be a useful complement to ‘infrastructural warfare’ research, suggesting the study of protracted armed conflict upon all aspects of urban life be both deepened technically and broadened to other cases

Balancing Innovation and Operation in Organizations:A Multiple Case Study on Ambidexterity

Background: Since quick change is one of the most distinguishing qualities of today's market, organizations must be able to cope with it and match markets by keeping up with new market trends and wants, as well as adapting to changes in market features. This can be achieved by pursuing both exploration and exploitation to ensure success in the short and long term. Since this is the case, it is vital that companies find the right balance between operation and innovation to be able to exploit present opportunities and explore future directions. Purpose: This research aims to study the role of ambidexterity in achieving the desired balance in different industries. Every organization is unique, and companies differ from each other in many ways such as; work system, organizational structure, work philosophy and size. This study discussed the issue of balancing innovation and operation, to evaluate the process of choosing the right ambidextrous approach to be followed by different organizations across different industries. Method: Multiple case study was used. Data collected had both primary and secondary sources where the primary sources were collected through semi-structured interviews and the secondary sources were archives and reports. Grounded analysis was used in the analysis process to conclude the theory. Conclusion: The research results showed that when organizations achieve ambidexterity by following one of the ambidexterity approaches, the choice of the right approach depends on certain factors on different levels that need to be considered, and the four tensions of ambidexterity differ from one approach to another. Hence, the tensions should be verified and handled in relevance to the followed ambidexterity approach

Antiphospholipid Antibody Induced by Nivolumab

Nivolumab is a monoclonal antibody against the programmed death protein 1 and is used for patients with advanced melanoma. It is associated with potentially immune-related adverse events, including disorders of the skin, GI tract, and the thyroid; these disorders were successfully treated with prednisone and infliximab. Other immunotherapeutic agents were observed to induce the formation of antiphospholipid antibody (APA) including α-interferon and interleukin-2. We present a case of APA development after the third dose of nivolumab in a 71-year-old male with advanced melanoma. The APA was detected after finding a prolonged aPTT; the lupus anticoagulant assay tested positive. The patient was treated with prednisone but, unfortunately, he expired a few days later