70 research outputs found

    A training monitoring system for cyclist based on wireless sensor networks

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    This paper presents a training monitoring system for cyclist that is based on the technology of wireless sensor networks (WSNs). A stable and reliable wireless cyclist monitoring system is vital to establish a smart and efficient sports management program. A training monitoring system has been developed and tested in a real cyclist training environment in a velodrome. The system is designed is such a way that the packet loss rate is minimum. Using TelG mote as the basis, customized sensor nodes that function as a forwarder node and the relay nodes are developed to form the WSN. This WSN is linked to the cloud network on the Internet. The cloud network is then established and end users application for data accessing is designed. Several experiments have been conducted in a real scenario in a velodrome to measure the reliability of the system architecture. It is shown from the experiments that the proposed system is reliable even when the cyclist is moving at a high speed. The packet loss is less than 2% which does not give a huge impact to the data transmission

    Batch study on COD and ammonia nitrogen removal using granular activated carbon and cockle shells

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    Landfills generate leachate that contains elevated concentration of contaminants and is hazardous to human health and the ecosystem. In this study, the mixture of granular activated carbon and cockle shells was investigated for remediation of COD and ammonia from stabilized landfill leachate. All adsorbent media were sieved to a particle size between 2.00 and 3.35 mm. The optimum mixing ratio, shaking speed, shaking time, pH, and dosage were determined. Characterization results show that the leachate had a high concentration of COD (1763 mg/L), ammonia nitrogen (573 mg/L), and BOD5/COD ratio (0.09). The optimum mixing ratio of granular activated carbon and cockle shells was 20:20, shaking speed 150 rpm, pH level 6, shaking time 120 min, and dosage 32 g. The adsorption isotherm analysis reveals that the Langmuir isotherm yielded the best fit to experimental data as compared with the Freundlich isotherm. The media produce encouraging results and can be used as a good and economical adsorbent

    Perception of Subject Matter Experts (SMEs) on various curation and preservation techniques for the development of natural history gallery in Malaysia: a qualitative study

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    Preserving animal’s body or part of the animals have become an important and wellknown conservation medium to ensure that the future generations are still able to enjoy the biodiversity and all the incredible species that live within it. This paper aims to present a qualitative study on perception and preference of subject matter experts (SMEs) on various curation and preservation methods that is suitable for certain animals for the development of Natural History Gallery. Interview with the SMEs were done by using semi-structured questionnaire and prior to this, permission were gained from the respondents by signing the Informed Consent Form (ICF). The findings suggest that the preservation methods of specimens ultimately depend on the purpose of specimens collected, either to be preserved as research specimens or exhibition specimens. The information gained form this study will be valuable as directive for the development of natural history gallery in Malaysia

    Is Malaysia’s banded langur, Presbytis femoralis femoralis, actually Presbytis neglectus neglectus? Taxonomic revision with new insights on the radiation history of the Presbytis species group in Southeast Asia

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    The disjunct distribution of Presbytis femoralis subspecies across Sumatra (P. f. percura), southern (P. f. femoralis) and northern (P. f. robinsoni) Peninsular Malaysia marks the unique vicariance events in the Sunda Shelf. However, the taxonomic positions and evolutionary history of P. f. femoralis are unresolved after decades of research. To elucidate this evolutionary history, we analyzed 501 base pairs of the mitochondrial HVSI gene from 25 individuals representing Malaysia’s banded langur, with the addition of 29 sequences of Asian Presbytis from Genbank. Our results revealed closer affinity of P. f. femoralis to P. m. mitrata and P. m. sumatrana while maintaining the monophyletic state of P. f. femoralis as compared to P. f. robinsoni. Two central theses were inferred from the results; (1) P. f. femoralis does not belong in the same species classification as P. f. robinsoni, and (2) P. f. femoralis is the basal lineage of the Presbytis in Peninsular Malaysia. Proving the first hypothesis through genetic analysis, we reassigned P. f. femoralis of Malaysia to Presbytis neglectus (Schlegel’s banded langur) (Schlegel in Revue Methodique, Museum d’Histoire Naturelle des Pays-Bas 7:1, 1876) following the International Code of Zoological Nomenclature (article 23.3). The ancestors of P. neglectus are hypothesized to have reached southern Peninsular Malaysia during the Pleistocene and survived in refugium along the western coast. Consequently, they radiated upward, forming P. f. robinsoni and P. siamensis resulting in the highly allopatric distribution in Peninsular Malaysia. This study has successfully resolved the taxonomic position of P. neglectus in Peninsular Malaysia while providing an alternative biogeographic theory for the Asian Presbytis

    ARIA-EAACI statement on asthma and COVID-19 (June 2, 2020)

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    ARIA-EAACI care pathways for allergen immunotherapy in respiratory allergy

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    A concept for integrated care pathways for atopic dermatitis-A GA2 LEN ADCARE initiative

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    INTRODUCTION: The integrated care pathways for atopic dermatitis (AD-ICPs) aim to bridge the gap between existing AD treatment evidence-based guidelines and expert opinion based on daily practice by offering a structured multidisciplinary plan for patient management of AD. ICPs have the potential to enhance guideline recommendations by combining interventions and aspects from different guidelines, integrating quality assurance, and describing co-ordination of care. Most importantly, patients can enter the ICPs at any level depending on AD severity, resources available in their country, and economic factors such as differences in insurance reimbursement systems. METHODS: The GA2 LEN ADCARE network and partners as well as all stakeholders, abbreviated as the AD-ICPs working group, were involved in the discussion and preparation of the AD ICPs during a series of subgroup workshops and meetings in years 2020 and 2021, after which the document was circulated within all GAL2 EN ADCARE centres. RESULTS: The AD-ICPs outline the diagnostic procedures, possible co-morbidities, different available treatment options including differential approaches for the pediatric population, and the role of the pharmacists and other stakeholders, as well as remaining unmet needs in the management of AD. CONCLUSION: The AD-ICPs provide a multidisciplinary plan for improved diagnosis, treatment, and patient feedback in AD management, as well as addressing critical unmet needs, including improved access to care, training specialists, implementation of educational programs, assessment on the impact of climate change, and fostering a personalised treatment approach. By focusing on these key areas, the initiative aims to pave the way for a brighter future in the management of AD

    Is diet partly responsible for differences in COVID-19 death rates between and within countries?

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    Correction: Volume: 10 Issue: 1 Article Number: 44 DOI: 10.1186/s13601-020-00351-w Published: OCT 26 2020Reported COVID-19 deaths in Germany are relatively low as compared to many European countries. Among the several explanations proposed, an early and large testing of the population was put forward. Most current debates on COVID-19 focus on the differences among countries, but little attention has been given to regional differences and diet. The low-death rate European countries (e.g. Austria, Baltic States, Czech Republic, Finland, Norway, Poland, Slovakia) have used different quarantine and/or confinement times and methods and none have performed as many early tests as Germany. Among other factors that may be significant are the dietary habits. It seems that some foods largely used in these countries may reduce angiotensin-converting enzyme activity or are anti-oxidants. Among the many possible areas of research, it might be important to understand diet and angiotensin-converting enzyme-2 (ACE2) levels in populations with different COVID-19 death rates since dietary interventions may be of great benefit.Peer reviewe

    Twelve-month observational study of children with cancer in 41 countries during the COVID-19 pandemic

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    Introduction Childhood cancer is a leading cause of death. It is unclear whether the COVID-19 pandemic has impacted childhood cancer mortality. In this study, we aimed to establish all-cause mortality rates for childhood cancers during the COVID-19 pandemic and determine the factors associated with mortality. Methods Prospective cohort study in 109 institutions in 41 countries. Inclusion criteria: children <18 years who were newly diagnosed with or undergoing active treatment for acute lymphoblastic leukaemia, non-Hodgkin's lymphoma, Hodgkin lymphoma, retinoblastoma, Wilms tumour, glioma, osteosarcoma, Ewing sarcoma, rhabdomyosarcoma, medulloblastoma and neuroblastoma. Of 2327 cases, 2118 patients were included in the study. The primary outcome measure was all-cause mortality at 30 days, 90 days and 12 months. Results All-cause mortality was 3.4% (n=71/2084) at 30-day follow-up, 5.7% (n=113/1969) at 90-day follow-up and 13.0% (n=206/1581) at 12-month follow-up. The median time from diagnosis to multidisciplinary team (MDT) plan was longest in low-income countries (7 days, IQR 3-11). Multivariable analysis revealed several factors associated with 12-month mortality, including low-income (OR 6.99 (95% CI 2.49 to 19.68); p<0.001), lower middle income (OR 3.32 (95% CI 1.96 to 5.61); p<0.001) and upper middle income (OR 3.49 (95% CI 2.02 to 6.03); p<0.001) country status and chemotherapy (OR 0.55 (95% CI 0.36 to 0.86); p=0.008) and immunotherapy (OR 0.27 (95% CI 0.08 to 0.91); p=0.035) within 30 days from MDT plan. Multivariable analysis revealed laboratory-confirmed SARS-CoV-2 infection (OR 5.33 (95% CI 1.19 to 23.84); p=0.029) was associated with 30-day mortality. Conclusions Children with cancer are more likely to die within 30 days if infected with SARS-CoV-2. However, timely treatment reduced odds of death. This report provides crucial information to balance the benefits of providing anticancer therapy against the risks of SARS-CoV-2 infection in children with cancer
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