The cultural politics of human rights and neoliberalism

Do human rights offer the potential to challenge neo-liberalism? I argue that rather than understanding human rights as ideology, as obscuring or legitimating neo-liberalism, it is more productive to see both human rights and neo-liberalism as hegemonic projects. In this article I explore convergences and divergences between dominant discourses and practices of human rights and neo-liberalism around key ideas ‘the state’, ‘the individual’ and ‘the nation’, to clear a space for appreciation of the cultural politics of human rights: divergences in constructions of responsibility and hierarchies of value of concrete individuals offer openings for challenging ideas and practices of neo-liberalism through campaigns for human rights

Finishing the euchromatic sequence of the human genome

The sequence of the human genome encodes the genetic instructions for human physiology, as well as rich information about human evolution. In 2001, the International Human Genome Sequencing Consortium reported a draft sequence of the euchromatic portion of the human genome. Since then, the international collaboration has worked to convert this draft into a genome sequence with high accuracy and nearly complete coverage. Here, we report the result of this finishing process. The current genome sequence (Build 35) contains 2.85 billion nucleotides interrupted by only 341 gaps. It covers ∼99% of the euchromatic genome and is accurate to an error rate of ∼1 event per 100,000 bases. Many of the remaining euchromatic gaps are associated with segmental duplications and will require focused work with new methods. The near-complete sequence, the first for a vertebrate, greatly improves the precision of biological analyses of the human genome including studies of gene number, birth and death. Notably, the human enome seems to encode only 20,000-25,000 protein-coding genes. The genome sequence reported here should serve as a firm foundation for biomedical research in the decades ahead

A Portrait of an Integrating School: Equity High

This research study seeks to understand how a former Afrikaans medium school, named after a prominent president of the apartheid era and steeped within the proud traditions and customs of the Afrikaans culture, went against the grain to become a shining beacon of democracy in South Africa. Utilising the methodology of portraiture this research study draws attention to the outstanding qualities of this school, Equity High, studying excellence rather than pathology. Three major research findings emanated from this study: first, a transitory leader that is committed to humanistic principles and norms can effect positive educational change; second, if change attempts are to be successful, individuals and groups must find meaning concerning what should change as well as how to go about it; and third, a school climate that promotes cultural interconnectedness and cultural interdependency can foster a sense of belonging and a feeling at home for all students at school

Prenatal and childhood traffic-related air pollution exposure and childhood executive function and behavior

BACKGROUND: Traffic-related air pollution exposure may influence brain development and function and thus be related to neurobehavioral problems in children, but little is known about windows of susceptibility. AIMS: Examine associations of gestational and childhood exposure to traffic-related pollution with executive function and behavior problems in children. METHODS: We studied associations of pre- and postnatal pollution exposures with neurobehavioral outcomes in 1,212 children in the Project Viva pre-birth cohort followed to mid-childhood (median age 7.7 years). Parents and classroom teachers completed the Behavior Rating Inventory of Executive Function (BRIEF), and the Strengths and Difficulties Questionnaire (SDQ). Using validated spatiotemporal models, we estimated exposure to black carbon (BC) and fine particulate matter (PM(2.5)) in the third trimester of pregnancy, from birth to 3 years, from birth to 6 years, and in the year before behavioral ratings. We also measured residential distance to major roadways and near-residence traffic density at birth and in mid-childhood. We estimated associations of BC, PM(2.5), and other traffic exposure measures with BRIEF and SDQ scores, adjusted for potential confounders. RESULTS: Higher childhood BC exposure was associated with higher teacher-rated BRIEF Behavioral Regulation Index (BRI) scores, indicating greater problems: 1.0 points (95% confidence interval (CI): 0.0, 2.1) per interquartile range (IQR) increase in birth-age 6 BC, and 1.7 points (95% CI: 0.6, 2.8) for BC in the year prior to behavioral ratings. Mid-childhood residential traffic density was also associated with BRI score (0.6, 95% CI: 0.1, 1.1). Birth-age 3 BC was not associated with BRIEF or SDQ scores. Third trimester BC exposure was not associated with teacher-rated BRI scores (−0.2, 95% CI: −1.1, 0.8), and predicted lower scores (fewer problems) on the BRIEF Metacognition Index (−1.2, 95% CI: −2.2, −0.2) and SDQ total difficulties (−0.9, 95% CI: −1.4, −0.4). PM(2.5) exposure was associated with teacher-rated BRIEF and SDQ scores in minimally adjusted models but associations attenuated with covariate adjustment. None of the parent-rated outcomes suggested adverse effects of greater pollution exposure at any time point. CONCLUSIONS: Children with higher mid-childhood exposure to BC and greater near-residence traffic density in mid-childhood had greater problems with behavioral regulation as assessed by classroom teachers, but not as assessed by parents. Prenatal and early childhood exposure to traffic-related pollution did not predict greater executive function or behavior problems; third trimester BC was associated with lower scores (representing fewer problems) on measures of metacognition and behavioral problems