Imaging and Recording Subventricular Zone Progenitor Cells in Live Tissue of Postnatal Mice

The subventricular zone (SVZ) is one of two regions where neurogenesis persists in the postnatal brain. The SVZ, located along the lateral ventricle, is the largest neurogenic zone in the brain that contains multiple cell populations including astrocyte-like cells and neuroblasts. Neuroblasts migrate in chains to the olfactory bulb where they differentiate into interneurons. Here, we discuss the experimental approaches to record the electrophysiology of these cells and image their migration and calcium activity in acute slices. Although these techniques were in place for studying glial cells and neurons in mature networks, the SVZ raises new challenges due to the unique properties of SVZ cells, the cellular diversity, and the architecture of the region. We emphasize different methods, such as the use of transgenic mice and in vivo electroporation that permit identification of the different SVZ cell populations for patch clamp recording or imaging. Electroporation also permits genetic labeling of cells using fluorescent reporter mice and modification of the system using either RNA interference technology or floxed mice. In this review, we aim to provide conceptual and technical details of the approaches to perform electrophysiological and imaging studies of SVZ cells

Stereoelectronic control of photophysics:red and yellow axial and equatorial anomers of a rhenium-quinoline complex

A novel quinoline-substituted pyrimidine ligand forms two different coloured complexes upon reaction with Re(CO)(5)Br. These compounds display distinct photophysical properties that are dictated by their stereochemistry

Quantum-inspired feature and parameter optimization of evolving spiking neural networks with a case study from ecological modelling

The paper introduces a framework and implementation of an integrated connectionist system, where the features and the parameters of an evolving spiking neural network are optimised together using a quantum representation of the features and a quantum inspired evolutionary algorithm for optimisation. The proposed model is applied on ecological data modeling problem demonstrating a significantly better classification accuracy than traditional neural network approaches and a more appropriate feature subset selected from a larger initial number of features. Results are compared to a naive Bayesian classifier

Pour une socio-histoire de la reconnaissance en maladie professionnelle : fondements historiques et dynamiques de la réparation des cancers liés au travail

L'indemnisation des maladies professionnelles est régie par des principes restrictifs établis il y a plus d'une centaine d'années, issus du compromis de 1898 sur les accidents du travail : réparation automatique et forfaitaire en contrepartie de l'absence de responsabilité de l'employé et de l'immunité de l'employeur. La force des rapports sociaux antagoniques et inégaux qui marquèrent la construction de la législation des risques professionnels en régit encore de nos jours tant sa mise en application que son évolution, entraînant retard et restrictions dans la connaissance et la prévention des maladies professionnelles. Les cancers liés au travail, qui souffrent chroniquement de sous-reconnaissance en maladie professionnelle, sont amplement concernés par ce phénomène. Ce rapport rappelle les logiques sur lesquelles s'est construit le principe restrictif de l'indemnisation des pathologies professionnelles, puis, comment, la réparation des cancers liés au travail s'est inscrite dans ce contexte

A comparative study of two processes for indoor vocs treatment: biofiltration vs. hybrid system (biological process+adsorption)

Biofiltration technology and the hybrid system combining biofiltration and adsorption (onto activated carbon) were compared as possible methods to treat indoor air pollution. Toluene and p-xylene at ppb concentration levels (2-45 and 1-33 ppb, respectively) were chosen as characteristic indoor pollutants for this study. An organic material was used as packing material for the biofiltration stage and its acclimation was carried out for 100 days at higher concentrations. Even at low empty bed residence time (EBRTs) and concentrations, toluene removal efficiency reached 100% and p-xylene showed an increasing trend in their removal efficiency over the time. The assessment of by-products and particles generation by the biofilter and the hybrid systems was taken into account. Acetone and acetic acid were identified as by-products of the biofilter. Particle emissions in the range of 0.03 to 10 µm were recorded for both systems which suggest the necessity of using a particle filter at the end of the process chain. Please click Additional Files below to see the full abstract