9 research outputs found
An ultrasonic frequency sweep interferometer for liquids at high temperature: 1. Acoustic model
Full text linkPeer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/95075/1/jgrb14010.pd
Neurophysiological Approaches to the Diagnosis and Correction of Vestibular Impairments in Migraine and Epilepsy
No full textNuclear envelope structural proteins facilitate nuclear shape changes accompanying embryonic differentiation and fidelity of gene expression
No full textNanomedicines for dysfunctional macrophage-associated diseases
No full textMacrophages play vital functions in host inflammatory reaction, tissue repair, homeostasis and immunity. Dysfunctional macrophages have significant pathophysiological impacts on diseases such as cancer, inflammatory diseases (rheumatoid arthritis and inflammatory bowel disease), metabolic diseases (atherosclerosis, diabetes and obesity) and major infections like human immunodeficiency virus. In view of this common etiology in these diseases, targeting the recruitment, activation and regulation of dysfunctional macrophages represents a promising therapeutic strategy. With the advancement of nanotechnology, development of nanomedicines to efficiently target dysfunctional macrophages can strengthen the effectiveness of therapeutics and improve clinical outcomes. This review discusses the specific roles of dysfunctional macrophages in various diseases and summarizes the latest advances in nanomedicine-based therapeutics and theranostics for treating diseases associated with dysfunctional macrophages
Nuclear peripheral chromatin-lamin B1 interaction is required for global integrity of chromatin architecture and dynamics in human cells
No full text
