Thermal imprinting modifies adult stress and innate immune responsiveness in the teleost sea bream

The impact of thermal imprinting on the plasticity of the hypothalamic-pituitary-interrenal (HPI) axis and stress response in an adult ectotherm, the gilthead sea bream (Sparus aurata, L.), during its development was assessed. Fish were reared under 4 thermal regimes, and the resulting adults exposed to acute confinement stress and plasma cortisol levels and genes of the HPI axis were monitored. Changes in immune function, a common result of stress, were also evaluated using histomorphometric measurements of melanomacrophages centers (MMCs) in the head kidney and by monitoring macrophage-related transcripts. Thermal history significantly modified the HPI responsiveness in adult sea bream when eggs and larvae were reared at a higher than optimal temperature (HT, 22 degrees C), and they had a reduced amplitude in their cortisol response and significantly upregulated pituitary pomc and head kidney star transcripts. Additionally, after an acute stress challenge, immune function was modified and the head kidney of adult fish reared during development at high temperatures (HT and LHT, 18-22 degrees C) had a decreased number of MMCs and a significant downregulation of dopachrome tautomerase. Thermal imprinting during development influenced adult sea bream physiology and increased plasma levels of glucose and sodium even in the absence of an acute stress in fish reared under a high-low thermal regime (HLT, 22-18 degrees C). Overall, the results demonstrate that temperature during early development influences the adult HPI axis and immune function in a teleost fish.project Lifecycle EU-FP7 [222719]FCT- Foundation for Science and Technology [CCMAR/Multi/04326/2013]info:eu-repo/semantics/publishedVersio

Síndrome uña-rótula

Presentamos el estudio de 3 casos afectos de un síndrome "uña-rótula", con historia familiar positiva en uno de ellos. Este síndrome es un transtorno hereditario de transmisión autosómica dominante, caracterizado por displasia ungueal y de articulacione s y formación de una s excrecencia s óseas características a nive l del ilíaco (cuernos ilíacos). El síndrome completo se define por los cambios esqueléticos asociados a una nefropatía. Describimos las anomalías clínico-radiográficas de tres paciente s y realizamos una revisión de la literatura sobre esta displasia poco frecuente.The author s showed thre e patients affected by "nail patella" syndrome with positive familiar history in one case. The "nail patella" syndrome is an autosomal dominant condition, characterized by nail and joint dysplasia and extra bone formation at the os ilium. The complet e syndrome is characterized by a serie s of skeletal disorders and specific nephropathy. This article reports the clinical and roentgenographi c findings of three patients and the results of the study of their families. A review of the literature is done

Pumping seawater from coastal aquifers for supplying desalination plants

The lack of water in the coastal areas demands an onerous search for an appropriate solution. One solution is that of water transfer from areas of surplus, but this is itself problematical. Technological developments have introduced the possibility of utilizing desalinated seawater as a drinking water source at a competitive price. Abstraction from coastal aquifers that are connected to the sea appears to be the cheapest means of supply. However, pumping poses some problems due to the corrosiveness of seawater. These problems include the difficulties of choosing suitable sites for the abstractions, drilling method, casing, filter pack, as well as the design of a monitoring system to assess aquifer behaviour as a result of the generally high exploitation rate. The 31 boreholes that have been drilled in the Andarax Delta near the city of Almeria are cited as an example of a real application

Efecto de dosis de acido polimaleico en la estabilidad estructural de suelos salinos.

Se estudió el efecto de distintas dosis de ácido polimaleico sobre la estabilidad estructural de tres tipos de suelos salinos. Se separaron los agregados naturales que pasaron por el tamiz de 4,00 mm y quedaron retenidos en el tamiz de 2,00 mm, se aplicaron dosis de ácido polimaleico de 0,5, 10 y 15 L/ha sobre los agregados. Cada 30 dias se determinó la distribución de agregados estables y el porcentage de arcilla dispersa en agua. Para los tres tipos de suelos las dosis más elevadas presentaron un mayor aumento del diámetro medio ponderado de los agregados y mayor reducción del porcentaje de arcilla dispersa en agua

Roturas agudas de L.C.A. de la rodilla: refuerzo con cordón RD.S

Se presenta la técnica de reconstrucción en las roturas agudas del L.C.A. mediante reparación con cordón de P.D.S., así como los criterios seguidos por los autores ante las roturas agudas de dicho ligamento. Expone una casuística de 24 intervenciones, con un seguimiento de 1.5 años, sin haber encontrado complicaciones destacables y con un 75% de Muy Buenos Resultados y un 25% de Buenos Resultados.The technique used in the repair of acute rupture of the ACL with a band of PDS, together with the criteria followed by our department in such cases both acute are decribed. The describe 24 operations performed by them, with a follow-up of 1.5 years, with no major complications, 75% excellent results and 25% good results

Artroplastia de rodilla: nuestra experiencia

Se presenta una casuística de 209 prótesis tricompartimentales de deslizamiento respetando el LCP, de las que 52 fueron PCA y 150 AGC, cementadas y sin cementar y 7 ICLH, implantadas desde 1980 a 1990, con un seguimiento medio de 4.5 años, obteniendo un 40% de Muy Buenos Resultados, un 51% de Buenos Resultados, 5% Regulares y 4% de Malos. No se encontraron diferencias significativas entre cementadas y sin cementar. Se presentaron complicaciones en 9,56% de los casos. Se expone la técnica quirúrgica así como las conclusiones prácticas de nuestra experiencia.A series of 209 prosthesis with three sliding compartiments retaining the PCL are presented, of these 52 were PCA and 150 AGC, with or without cement, and 7 ICLH, implanted between 1980 and 1990, with and average follow-up of 4.5 years. The results wer e 40% very good, 51% good, 5% fair and 4% poor. No singnificant difference was seen between those cemented and cementlers. Complications occurred in 9.56% of theese patients. The surgical technique used and practical conclusions drown, are described